Mitochondrial myopathy and comorbid major depressive disorder: Effectiveness of dTMS on gait and mood symptoms

General Hospital Psychiatry

Volumn 37, Issue 3, 2015, Pages 274.e7-274.e9

  Rapinesi, Chiara ^a,b   Janiri, Delfina ^a   Kotzalidis, Georgios D ^a   Serata, Daniele ^a,b   Del Casale, Antonio ^a,c   Scatena, Paola ^b   Dacquino, Claudia ^a   Gentile, Giovanna ^d   Manfredi, Giovanni ^a   Danese, Emanuela ^a   Raccah, Ruggero Nessim ^e   Brugnoli, Roberto ^a   Callovini, Gemma ^a   Ferri, Vittoria Rachele ^a   Ferracuti, Stefano ^a   Zangen, Abraham ^f   Simmaco, Maurizio ^d   Angeletti, Gloria ^a   Girardi, Paolo ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Villa Rosa   (Italy)

^c ONLUS Fondazione Padre Alberto Mileno   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e ATID Ltd Advanced Technology   (Italy)

^f BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Comorbidity; Deep transcranial magnetic stimulation (dTMS); Dorsolateral prefrontal cortex (DLPFC); Major depressive disorder; Mitochondrial myopathy

Indexed keywords

ALPRAZOLAM; ESCITALOPRAM; HALOPERIDOL; MIRTAZAPINE; NORDAZEPAM; PAROXETINE; RISPERIDONE; SULPIRIDE; VENLAFAXINE; ZOLPIDEM;

ACHILLES REFLEX; AGED; ANXIETY; APATHY; ARTICLE; AUDIOMETRY; BABINSKI REFLEX; CASE REPORT; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CLINICAL EFFECTIVENESS; COGNITION; COMORBIDITY; CRYING; DEEP TRANSCRANIAL MAGNETIC STIMULATION; DEPRESSION; DISEASE COURSE; DISEASE SEVERITY; DORSOLATERAL PREFRONTAL CORTEX; DRUG EFFICACY; DYSARTHRIA; DYSMETRIA; DYSPHAGIA; DYSPHONIA; ECHOCARDIOGRAPHY; ELECTROENCEPHALOGRAM; ELECTROMYOGRAPHY; EXECUTIVE FUNCTION; FAMILY HISTORY; FATIGUE; FEMALE; GAIT; GENETIC ANALYSIS; HAMILTON DEPRESSION RATING SCALE; HEARING IMPAIRMENT; HOSPITAL READMISSION; HUMAN; HUMAN TISSUE; LEUKOENCEPHALOPATHY; MAJOR DEPRESSION; MEDICAL HISTORY; MITOCHONDRIAL MYOPATHY; MITRAL VALVE PROLAPSE; MOOD DISORDER; MOTOR DYSFUNCTION; MUSCLE HYPERTONIA; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; NYSTAGMUS; PANIC; PERCEPTION DEAFNESS; PSYCHOSOCIAL WITHDRAWAL; PTOSIS; SUICIDAL IDEATION; SYNKINESIS; THETA RHYTHM; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT DURATION; TREMOR; VALVULAR HEART DISEASE; VISUAL DISORDER; COMPLICATION; DEPRESSIVE DISORDER, MAJOR; MITOCHONDRIAL MYOPATHIES; PHYSIOLOGY; PROCEDURES;

AGED; COMORBIDITY; DEPRESSIVE DISORDER, MAJOR; FEMALE; GAIT; HUMANS; MITOCHONDRIAL MYOPATHIES; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 84930181610     PISSN: 01638343     EISSN: 18737714     Source Type: Journal    
DOI: 10.1016/j.genhosppsych.2015.03.002     Document Type: Article

References (10)

1. Fattal O., Link J., Quinn K., Cohen B.H., Franco K. Psychiatric comorbidity in 36 adults with mitochondrial cytopathies. CNS Spectr 2007, 12:429-438.
2. Manji H., Kato T., Di Prospero N.A., Ness S., Beal M.F., Krams M., et al. Impaired mitochondrial function in psychiatric disorders. Nat Rev Neurosci 2012, 13:293-307.
3. Anglin R., Rosebush P., Mazurek M. Psychotropic medications and mitochondrial toxicity. Nat Rev Neurosci 2012, 13:650.
4. Lacey C.J., Salzberg M.R. Obsessive-compulsive disorder with mitochondrial disease. Psychosomatics 2008, 49:540-542.
5. Anglin R.E., Garside S.L., Tarnopolsky M.A., Mazurek M.F., Rosebush P.I. The psychiatric manifestations of mitochondrial disorders: a case and review of the literature. J Clin Psychiatry 2012, 73:506-512.
6. Anglin R.E., Rosebush P.I., Mazurek M.F. Treating psychiatric illness in patients with mitochondrial disorders. Psychosomatics 2010, 51:179.
7. Hroudová J., Fišar Z. In vitro inhibition of mitochondrial respiratory rate by antidepressants. Toxicol Lett 2012, 213:345-352.
8. Levkovitz Y., Harel E.V., Roth Y., Braw Y., Most D., Katz L.N., et al. Deep transcranial magnetic stimulation over the prefrontal cortex: evaluation of antidepressant and cognitive effects in depressive patients. Brain Stimul 2009, 2:188-200.
9. Valk J., van der Knaap M.S. Magnetic resonance of myelin, myelination, and myelin disorders. Chapter 24: Mitochondrial Leukoencephalopathy 1989, 130-136. Springer Verlag, Berlin.
10. de Sousa R.T., Uno M., Zanetti M.V., Shinjo S.M., Busatto G.F., Gattaz W.F., et al. Leukocyte mitochondrial DNA copy number in bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 2014, 48:32-35.