The road to mitochondrial gene transfer: Follow the middle lane

Molecular Therapy

Volumn 23, Issue 6, 2015, Pages 975-976

  Bredenoord, A L ^a   Hyun, I ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA;

DISEASE SEVERITY; DNA TRANSPOSITION; EDITORIAL; ENERGY YIELD; FERTILIZATION IN VITRO; GENE TRANSFER; HUMAN; MEDICAL RESEARCH; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL GENE; MITOCHONDRIAL GENE TRANSFER; MITOCHONDRIAL GENOME; MUTATIONAL ANALYSIS; RISK ASSESSMENT; RISK FACTOR; UNITED KINGDOM; UNITED STATES; GENETICS;

DNA, MITOCHONDRIAL; GENE TRANSFER TECHNIQUES; GENES, MITOCHONDRIAL; HUMANS;

EID: 84930169289     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.79     Document Type: Editorial

References (4)

1. Taylor, RW and Turnbull, DW (2005). Mitochondrial DNA mutations in human disease. Nat Rev Genet 6: 389-402
2. Bredenoord, AL, Pennings, G and De Wert, G (2008). Ooplasmic transfer and nuclear transfer to prevent mitochondrial DNA disorders: conceptual and normative issues. Hum Reprod Update 14: 669-678
3. Hyun, I (2014). Regulate embryos made for research. Nature 509: 27-28
4. Bredenoord, AL and Braude, P (2010). Ethics of mitochondrial gene replacement: from bench to bedside. BMJ 341: c6021