IL-21R signaling suppresses IL-17+ gamma delta T cell responses and production of IL-17 related cytokines in the lung at steady state and after influenza a virus infection

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Moser, Emily K ^a   Sun, Jie ^b   Kim, Taeg S ^a   Braciale, Thomas J ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; MESSENGER RNA;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CYTOKINE PRODUCTION; GAMMA DELTA T LYMPHOCYTE; HOST RESISTANCE; IMMUNOREGULATION; INFLUENZA A; INFLUENZA VIRUS A; KNOCKOUT MOUSE; LUNG LAVAGE; MOUSE; NONHUMAN; RESPIRATORY TRACT INFECTION; SIGNAL TRANSDUCTION; STEADY STATE; TH17 CELL; VIRAL CLEARANCE; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; C57BL MOUSE; CELL CULTURE; CHEMISTRY; FEMALE; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; INFLUENZA A VIRUS; LUNG; MALE; METABOLISM; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY;

INFLUENZA A VIRUS; MUS;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CYTOKINES; FEMALE; FLOW CYTOMETRY; INFLUENZA A VIRUS; INTERLEUKIN-17; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, INTERLEUKIN-21; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TH17 CELLS;

EID: 84930005080     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120169     Document Type: Article

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