Oral anticoagulation is frequently discontinued after ablation of paroxysmal atrial fibrillation despite previous stroke: data from the German Ablation Registry

Clinical Research in Cardiology

Volumn 104, Issue 6, 2015, Pages 463-470

  Nührich, Jana Mareike ^a   Kuck, Karl Heinz ^b   Andresen, Dietrich ^c   Steven, Daniel ^a   Spitzer, Stefan G ^d   Hoffmann, Ellen ^e   Schumacher, Burghard ^f   Eckardt, Lars ^g   Brachmann, Johannes ^h   Lewalter, Thorsten ⁱ   Hochadel, Matthias ^j   Senges, Jochen ^j   Willems, Stephan ^a   Hoffmann, Boris A ^a  

^a UNIVERSITY HEART CENTER HAMBURG   (Germany)

^b DEPARTMENT OF CARDIOLOGY   (Germany)

^c VIVANTES HOSPITAL   (Germany)

^d UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^e KLINIKUM BOGENHAUSEN   (Germany)

^f Westpfalz Klinikum GmbH   (Germany)

^g UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^h KLINIKUM COBURG   (Germany)

ⁱ Cardiovascular Surgery   (Germany)

^j Institute for Research in Myocardial Infarction   (Germany)

more..

Author keywords

Anticoagulation; Atrial fibrillation; Pulmonary vein isolation; Stroke; Thromboembolic complications

Indexed keywords

ACETYLSALICYLIC ACID; ANTIARRHYTHMIC AGENT; LOW MOLECULAR WEIGHT HEPARIN; ANTICOAGULANT AGENT;

ADULT; AGED; ANEURYSM; ANTICOAGULANT THERAPY; ARTICLE; BLEEDING; CATHETER ABLATION; CEREBROVASCULAR ACCIDENT; CHADS2 SCORE; COHORT ANALYSIS; COMPLETE HEART BLOCK; DRUG WITHDRAWAL; FEMALE; FIRST DEGREE ATRIOVENTRICULAR BLOCK; FOLLOW UP; GERMANY; HEART INFARCTION; HEART TAMPONADE; HIGH RISK PATIENT; HIGH RISK POPULATION; HUMAN; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OBSERVATIONAL STUDY; PAROXYSMAL ATRIAL FIBRILLATION; PRESCRIPTION; RECURRENT DISEASE; REPEAT PROCEDURE; SECOND DEGREE ATRIOVENTRICULAR BLOCK; SUDDEN CARDIAC DEATH; THROMBOEMBOLISM; TRANSIENT ISCHEMIC ATTACK; ATRIAL FIBRILLATION; CLINICAL TRIAL; COMPLICATION; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PROCEDURES; REGISTER; RISK; STROKE;

ADMINISTRATION, ORAL; AGED; ANTICOAGULANTS; ATRIAL FIBRILLATION; CATHETER ABLATION; FEMALE; FOLLOW-UP STUDIES; GERMANY; HUMANS; MALE; MIDDLE AGED; RECURRENCE; REGISTRIES; RISK; STROKE; THROMBOEMBOLISM;

EID: 84929966504     PISSN: 18610684     EISSN: 18610692     Source Type: Journal    
DOI: 10.1007/s00392-014-0804-1     Document Type: Article

References (18)

1. Wolf PA, Abbott RD, Kannel WB (1991) Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 22:983–988
2. Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De CR, De SJ, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH (2010) Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Europace 12:1360–1420
3. Ouyang F, Tilz R, Chun J, Schmidt B, Wissner E, Zerm T, Neven K, Kokturk B, Konstantinidou M, Metzner A, Fuernkranz A, Kuck KH (2010) Long-term results of catheter ablation in paroxysmal atrial fibrillation: lessons from a 5-year follow-up. Circulation 122:2368–2377
4. Calkins H, Reynolds MR, Spector P, Sondhi M, Xu Y, Martin A, Williams CJ, Sledge I (2009) Treatment of atrial fibrillation with antiarrhythmic drugs or radiofrequency ablation: two systematic literature reviews and meta-analyses. Circ Arrhythm Electrophysiol 2:349–361
5. Oral H, Chugh A, Ozaydin M, Good E, Fortino J, Sankaran S, Reich S, Igic P, Elmouchi D, Tschopp D, Wimmer A, Dey S, Crawford T, Pelosi F Jr, Jongnarangsin K, Bogun F, Morady F (2006) Risk of thromboembolic events after percutaneous left atrial radiofrequency ablation of atrial fibrillation. Circulation 114:759–765
6. Hunter RJ, McCready J, Diab I, Page SP, Finlay M, Richmond L, French A, Earley MJ, Sporton S, Jones M, Joseph JP, Bashir Y, Betts TR, Thomas G, Staniforth A, Lee G, Kistler P, Rajappan K, Chow A, Schilling RJ (2012) Maintenance of sinus rhythm with an ablation strategy in patients with atrial fibrillation is associated with a lower risk of stroke and death. Heart 98:48–53
7. Themistoclakis S, Corrado A, Marchlinski FE, Jais P, Zado E, Rossillo A, Di BL, Schweikert RA, Saliba WI, Horton R, Mohanty P, Patel D, Burkhardt DJ, Wazni OM, Bonso A, Callans DJ, Haissaguerre M, Raviele A, Natale A (2010) The risk of thromboembolism and need for oral anticoagulation after successful atrial fibrillation ablation. J Am Coll Cardiol 55:735–743
8. Guiot A, Jongnarangsin K, Chugh A, Suwanagool A, Latchamsetty R, Myles JD, Jiang Q, Crawford T, Good E, Pelosi F Jr, Bogun F, Morady F, Oral H (2012) Anticoagulant therapy and risk of cerebrovascular events after catheter ablation of atrial fibrillation in the elderly. J Cardiovasc Electrophysiol 23:36–43
9. Calkins H, Kuck KH, Cappato R, Brugada J, Camm AJ, Chen SA, Crijns HJ, Damiano RJ Jr, Davies DW, DiMarco J, Edgerton J, Ellenbogen K, Ezekowitz MD, Haines DE, Haissaguerre M, Hindricks G, Iesaka Y, Jackman W, Jalife J, Jais P, Kalman J, Keane D, Kim YH, Kirchhof P, Klein G, Kottkamp H, Kumagai K, Lindsay BD, Mansour M, Marchlinski FE, McCarthy PM, Mont JL, Morady F, Nademanee K, Nakagawa H, Natale A, Nattel S, Packer DL, Pappone C, Prystowsky E, Raviele A, Reddy V, Ruskin JN, Shemin RJ, Tsao HM, Wilber D (2012) 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design: a report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of Atrial Fibrillation. Developed in partnership with the European Heart Rhythm Association (EHRA), a registered branch of the European Society of Cardiology (ESC) and the European Cardiac Arrhythmia Society (ECAS); and in collaboration with the American College of Cardiology (ACC), American Heart Association (AHA), the Asia Pacific Heart Rhythm Society (APHRS), and the Society of Thoracic Surgeons (STS). Endorsed by the governing bodies of the American College of Cardiology Foundation, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, the Asia Pacific Heart Rhythm Society, and the Heart Rhythm Society. Heart Rhythm 9:632–696
10. Ouyang F, Bansch D, Ernst S, Schaumann A, Hachiya H, Chen M, Chun J, Falk P, Khanedani A, Antz M, Kuck KH (2004) Complete isolation of left atrium surrounding the pulmonary veins: new insights from the double-Lasso technique in paroxysmal atrial fibrillation. Circulation 110:2090–2096
11. Kornej J, Hindricks G, Kosiuk J, Arya A, Sommer P, Husser D, Rolf S, Richter S, Piorkowski C, Gaspar T, Lip GY, Bollmann A (2013) Renal dysfunction, stroke risk scores (CHADS2, CHA2DS2-VASc, and R2CHADS2), and the risk of thromboembolic events after catheter ablation of atrial fibrillation: the Leipzig Heart Center AF Ablation Registry. Circ Arrhythm Electrophysiol 6:868–874
12. Mardigyan V, Verma A, Birnie D, Guerra P, Redfearn D, Becker G, Champagne J, Sapp J, Gula L, Parkash R, Macle L, Crystal E, O’Hara G, Khaykin Y, Sturmer M, Veenhuyzen GD, Greiss I, Sarrazin JF, Mangat I, Novak P, Skanes A, Roux JF, Chauhan V, Hadjis T, Morillo CA, Essebag V (2013) Anticoagulation management pre- and post atrial fibrillation ablation: a survey of canadian centres. Can J Cardiol 29:219–223
13. Pisters R, Lane DA, Marin F, Camm AJ, Lip GY (2012) Stroke and thromboembolism in atrial fibrillation. Circ J 76:2289–2304
14. Lip GY (1995) Does atrial fibrillation confer a hypercoagulable state? Lancet 346:1313–1314
15. Chao TF, Ambrose K, Tsao HM, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Suenari K, Li CH, Hartono B, Chang HY, Wu TJ, Chen SA (2012) Relationship between the CHADS(2) score and risk of very late recurrences after catheter ablation of paroxysmal atrial fibrillation. Heart Rhythm 9:1185–1191
16. Chao TF, Lin YJ, Tsao HM, Tsai CF, Lin WS, Chang SL, Lo LW, Hu YF, Tuan TC, Suenari K, Li CH, Hartono B, Chang HY, Ambrose K, Wu TJ, Chen SA (2011) CHADS(2) and CHA(2)DS(2)-VASc scores in the prediction of clinical outcomes in patients with atrial fibrillation after catheter ablation. J Am Coll Cardiol 58:2380–2385
17. Bunch TJ, Crandall BG, Weiss JP, May HT, Bair TL, Osborn JS, Anderson JL, Muhlestein JB, Horne BD, Lappe DL, Day JD (2011) Patients treated with catheter ablation for atrial fibrillation have long-term rates of death, stroke, and dementia similar to patients without atrial fibrillation. J Cardiovasc Electrophysiol 22:839–845
18. Chao TF, Cheng CC, Lin WS, Tsao HM, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Suenari K, Li CH, Liu SH, Hartono B, Wu TJ, Chen SA (2011) Associations among the CHADS(2) score, atrial substrate properties, and outcome of catheter ablation in patients with paroxysmal atrial fibrillation. Heart Rhythm 8:1155–1159