메뉴 건너뛰기




Volumn 10, Issue 2, 2015, Pages 167-172

Milestones and Monitoring

Author keywords

BCR ABL; CML; RQ PCR; TK inhibitors

Indexed keywords

BCR ABL PROTEIN; MOLECULAR MARKER; PROTEIN TYROSINE KINASE INHIBITOR; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR; TUMOR MARKER;

EID: 84929943526     PISSN: 15588211     EISSN: 1558822X     Source Type: Journal    
DOI: 10.1007/s11899-015-0258-1     Document Type: Review
Times cited : (15)

References (38)
  • 1
    • 77957041355 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: a historical perspective
    • COI: 1:CAS:528:DC%2BC3cXht1SrurnI, PID: 20875546
    • Goldman JM. Chronic myeloid leukemia: a historical perspective. Semin Hematol. 2010;47:302–11.
    • (2010) Semin Hematol , vol.47 , pp. 302-311
    • Goldman, J.M.1
  • 2
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukemia—advances in biology and new approaches to treatment
    • COI: 1:CAS:528:DC%2BD3sXotVGgsLc%3D, PID: 14534339
    • Goldman JM, Melo JV. Chronic myeloid leukemia—advances in biology and new approaches to treatment. N Engl J Med. 2003;349:1451–64.
    • (2003) N Engl J Med , vol.349 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 3
    • 39049161669 scopus 로고    scopus 로고
    • Cytogenetic and molecular responses and outcome in chronic myelogenous leukemia: need for new response definitions?
    • PID: 18085610
    • Kantarjian H, O’Brien S, Shan J, et al. Cytogenetic and molecular responses and outcome in chronic myelogenous leukemia: need for new response definitions? Cancer. 2008;112:837–45.
    • (2008) Cancer , vol.112 , pp. 837-845
    • Kantarjian, H.1    O’Brien, S.2    Shan, J.3
  • 4
    • 58149396984 scopus 로고    scopus 로고
    • European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor
    • COI: 1:CAS:528:DC%2BD1cXhsVCltbzF, PID: 18716134
    • Marin D, Milojkovic D, Olavarria E, et al. European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor. Blood. 2008;112:4437–44.
    • (2008) Blood , vol.112 , pp. 4437-4444
    • Marin, D.1    Milojkovic, D.2    Olavarria, E.3
  • 5
    • 84881298446 scopus 로고    scopus 로고
    • European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013
    • Baccarani M, Deininger MW, Rosti G, et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood. 2013;122:872–84.
    • (2013) Blood , vol.122 , pp. 872-884
    • Baccarani, M.1    Deininger, M.W.2    Rosti, G.3
  • 7
    • 80055101170 scopus 로고    scopus 로고
    • Jabbour E, Kantarjian H, O’Brien S, et al. The achievement of an early complete cytogenetic response is a major determinant for outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors. Blood. 2011;118:4541–6. quiz 759. An important paper providing evidence for the opportunity to anticipate the expected timing of achievement of cytogenetic and molecular goals in optimal response evaluation.
    • Jabbour E, Kantarjian H, O’Brien S, et al. The achievement of an early complete cytogenetic response is a major determinant for outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors. Blood. 2011;118:4541–6. quiz 759. An important paper providing evidence for the opportunity to anticipate the expected timing of achievement of cytogenetic and molecular goals in optimal response evaluation.
  • 8
    • 84865864744 scopus 로고    scopus 로고
    • Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML)
    • Hanfstein B, Muller MC, Hehlmann R, et al. Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML). Leukemia. 2012.
    • (2012) Leukemia
    • Hanfstein, B.1    Muller, M.C.2    Hehlmann, R.3
  • 9
    • 84897574239 scopus 로고    scopus 로고
    • Deep molecular response is reached by the majority of patients treated with imatinib, predicts survival, and is achieved more quickly by optimized high-dose imatinib: results from the randomized CML-study IV
    • Hehlmann R, Muller MC, Lauseker M, et al. Deep molecular response is reached by the majority of patients treated with imatinib, predicts survival, and is achieved more quickly by optimized high-dose imatinib: results from the randomized CML-study IV. J Clin Oncol Off J Am Soc Clin Oncol. 2014;32:415–23.
    • (2014) J Clin Oncol Off J Am Soc Clin Oncol , vol.32 , pp. 415-423
    • Hehlmann, R.1    Muller, M.C.2    Lauseker, M.3
  • 10
    • 33745603988 scopus 로고    scopus 로고
    • Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
    • COI: 1:CAS:528:DC%2BD28XmsVOmt7Y%3D, PID: 16522812
    • Hughes T, Deininger M, Hochhaus A, et al. Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood. 2006;108:28–37.
    • (2006) Blood , vol.108 , pp. 28-37
    • Hughes, T.1    Deininger, M.2    Hochhaus, A.3
  • 11
    • 34548793961 scopus 로고    scopus 로고
    • An international study to standardize the detection and quantitation of BCR-ABL transcripts from stabilized peripheral blood preparations by quantitative RT-PCR
    • PID: 17606448
    • Muller MC, Saglio G, Lin F, et al. An international study to standardize the detection and quantitation of BCR-ABL transcripts from stabilized peripheral blood preparations by quantitative RT-PCR. Haematologica. 2007;92:970–3.
    • (2007) Haematologica , vol.92 , pp. 970-973
    • Muller, M.C.1    Saglio, G.2    Lin, F.3
  • 12
    • 84867405606 scopus 로고    scopus 로고
    • Standardized definitions of molecular response in chronic myeloid leukemia
    • COI: 1:CAS:528:DC%2BC38XhsFSgu7zL, PID: 22504141
    • Cross NC, White HE, Muller MC, Saglio G, Hochhaus A. Standardized definitions of molecular response in chronic myeloid leukemia. Leukemia. 2012;26:2172–5.
    • (2012) Leukemia , vol.26 , pp. 2172-2175
    • Cross, N.C.1    White, H.E.2    Muller, M.C.3    Saglio, G.4    Hochhaus, A.5
  • 13
    • 84929265404 scopus 로고    scopus 로고
    • Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia
    • Cross NC, White HE, Colomer D, et al. Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia. Leukemia. 2015.
    • (2015) Leukemia
    • Cross, N.C.1    White, H.E.2    Colomer, D.3
  • 14
    • 78049528573 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial
    • COI: 1:CAS:528:DC%2BC3cXhtlKmtrnP, PID: 20965785
    • Mahon FX, Rea D, Guilhot J, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol. 2010;11:1029–35.
    • (2010) Lancet Oncol , vol.11 , pp. 1029-1035
    • Mahon, F.X.1    Rea, D.2    Guilhot, J.3
  • 15
    • 84886917643 scopus 로고    scopus 로고
    • Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study
    • COI: 1:CAS:528:DC%2BC3sXht1SnurjJ, PID: 23704092
    • Ross DM, Branford S, Seymour JF, et al. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood. 2013;122:515–22.
    • (2013) Blood , vol.122 , pp. 515-522
    • Ross, D.M.1    Branford, S.2    Seymour, J.F.3
  • 16
    • 84897573995 scopus 로고    scopus 로고
    • Loss of major molecular response as a trigger for restarting tyrosine kinase inhibitor therapy in patients with chronic-phase chronic myelogenous leukemia who have stopped imatinib after durable undetectable disease
    • COI: 1:CAS:528:DC%2BC2cXls1Whsrw%3D
    • Rousselot P, Charbonnier A, Cony-Makhoul P, et al. Loss of major molecular response as a trigger for restarting tyrosine kinase inhibitor therapy in patients with chronic-phase chronic myelogenous leukemia who have stopped imatinib after durable undetectable disease. J Clin Oncol Off J Am Soc Clin Oncol. 2014;32:424–30.
    • (2014) J Clin Oncol Off J Am Soc Clin Oncol , vol.32 , pp. 424-430
    • Rousselot, P.1    Charbonnier, A.2    Cony-Makhoul, P.3
  • 17
    • 79955400117 scopus 로고    scopus 로고
    • Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia
    • COI: 1:CAS:528:DC%2BC3MXkvFarsbs%3D, PID: 21509757
    • Jabbour E, Branford S, Saglio G, Jones D, Cortes JE, Kantarjian HM. Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. Cancer. 2011;117:1800–11.
    • (2011) Cancer , vol.117 , pp. 1800-1811
    • Jabbour, E.1    Branford, S.2    Saglio, G.3    Jones, D.4    Cortes, J.E.5    Kantarjian, H.M.6
  • 18
    • 79953880772 scopus 로고    scopus 로고
    • Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib
    • COI: 1:CAS:528:DC%2BC3MXksFKjurg%3D, PID: 21422402
    • Gambacorti-Passerini C, Antolini L, Mahon FX, et al. Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib. J Natl Cancer Inst. 2011;103:553–61.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 553-561
    • Gambacorti-Passerini, C.1    Antolini, L.2    Mahon, F.X.3
  • 19
    • 84862907694 scopus 로고    scopus 로고
    • Marin D, Ibrahim AR, Lucas C, et al. Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. J Clin Oncol. 2012;30:232–8. An important paper providing evidence for the opportunity to anticipate the expected timing of achievement of cytogenetic and molecular goals in optimal response evaluation.
    • Marin D, Ibrahim AR, Lucas C, et al. Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. J Clin Oncol. 2012;30:232–8. An important paper providing evidence for the opportunity to anticipate the expected timing of achievement of cytogenetic and molecular goals in optimal response evaluation.
  • 20
    • 84865864744 scopus 로고    scopus 로고
    • Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML)
    • COI: 1:CAS:528:DC%2BC38XhtlWqsr%2FF, PID: 22446502
    • Hanfstein B, Muller MC, Hehlmann R, et al. Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML). Leukemia. 2012;26:2096–102.
    • (2012) Leukemia , vol.26 , pp. 2096-2102
    • Hanfstein, B.1    Muller, M.C.2    Hehlmann, R.3
  • 21
    • 84897007532 scopus 로고    scopus 로고
    • Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib
    • COI: 1:CAS:528:DC%2BC2cXkt1ajurY%3D, PID: 24335106
    • Hughes TP, Saglio G, Kantarjian HM, et al. Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib. Blood. 2014;123:1353–60.
    • (2014) Blood , vol.123 , pp. 1353-1360
    • Hughes, T.P.1    Saglio, G.2    Kantarjian, H.M.3
  • 22
    • 84893136765 scopus 로고    scopus 로고
    • Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION)
    • COI: 1:CAS:528:DC%2BC2cXisFagsbc%3D, PID: 24311723
    • Jabbour E, Kantarjian HM, Saglio G, et al. Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION). Blood. 2014;123:494–500.
    • (2014) Blood , vol.123 , pp. 494-500
    • Jabbour, E.1    Kantarjian, H.M.2    Saglio, G.3
  • 24
    • 49149111543 scopus 로고    scopus 로고
    • Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis
    • de Lavallade H, Apperley JF, Khorashad JS, et al. Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis. J Clin Oncol Off J Am Soc Clin Oncol. 2008;26:3358–63.
    • (2008) J Clin Oncol Off J Am Soc Clin Oncol , vol.26 , pp. 3358-3363
    • de Lavallade, H.1    Apperley, J.F.2    Khorashad, J.S.3
  • 25
    • 77953691179 scopus 로고    scopus 로고
    • Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
    • COI: 1:CAS:528:DC%2BC3cXnvVaktbk%3D, PID: 20525993
    • Saglio G, Kim DW, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med. 2010;362:2251–9.
    • (2010) N Engl J Med , vol.362 , pp. 2251-2259
    • Saglio, G.1    Kim, D.W.2    Issaragrisil, S.3
  • 26
    • 77953725855 scopus 로고    scopus 로고
    • Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
    • COI: 1:CAS:528:DC%2BC3cXnvVaktbY%3D, PID: 20525995
    • Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2010;362:2260–70.
    • (2010) N Engl J Med , vol.362 , pp. 2260-2270
    • Kantarjian, H.1    Shah, N.P.2    Hochhaus, A.3
  • 27
    • 84899072118 scopus 로고    scopus 로고
    • Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study
    • COI: 1:CAS:528:DC%2BC2cXms1CjtLo%3D, PID: 24569263
    • Shah NP, Guilhot F, Cortes JE, et al. Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study. Blood. 2014;123:2317–24.
    • (2014) Blood , vol.123 , pp. 2317-2324
    • Shah, N.P.1    Guilhot, F.2    Cortes, J.E.3
  • 28
    • 84867057517 scopus 로고    scopus 로고
    • Nilotinib in imatinib-resistant or -intolerant patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP): 48-month follow-up results of a phase 2 study
    • le Coutre PD, Giles FJ, Pinilla-Ibarz J, et al. Nilotinib in imatinib-resistant or -intolerant patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP): 48-month follow-up results of a phase 2 study. ASH Annu Meet Abstr. 2011;118:3770.
    • (2011) ASH Annu Meet Abstr , vol.118 , pp. 3770
    • le Coutre, P.D.1    Giles, F.J.2    Pinilla-Ibarz, J.3
  • 29
    • 0021336851 scopus 로고
    • Prognostic discrimination in “good-risk” chronic granulocytic leukemia
    • COI: 1:STN:280:DyaL2c7lsFSgtQ%3D%3D, PID: 6584184
    • Sokal JE, Cox EB, Baccarani M, et al. Prognostic discrimination in “good-risk” chronic granulocytic leukemia. Blood. 1984;63:789–99.
    • (1984) Blood , vol.63 , pp. 789-799
    • Sokal, J.E.1    Cox, E.B.2    Baccarani, M.3
  • 30
    • 0032478962 scopus 로고    scopus 로고
    • A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa. Writing Committee for the Collaborative CML Prognostic Factors Project Group
    • COI: 1:STN:280:DyaK1c3os1ygug%3D%3D, PID: 9625174
    • Hasford J, Pfirrmann M, Hehlmann R, et al. A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa. Writing Committee for the Collaborative CML Prognostic Factors Project Group. J Natl Cancer Inst. 1998;90:850–8.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 850-858
    • Hasford, J.1    Pfirrmann, M.2    Hehlmann, R.3
  • 31
    • 79960685618 scopus 로고    scopus 로고
    • Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score
    • COI: 1:CAS:528:DC%2BC3MXpslyhu7Y%3D, PID: 21536864
    • Hasford J, Baccarani M, Hoffmann V, et al. Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score. Blood. 2011;118:686–92.
    • (2011) Blood , vol.118 , pp. 686-692
    • Hasford, J.1    Baccarani, M.2    Hoffmann, V.3
  • 32
    • 77958595179 scopus 로고    scopus 로고
    • Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS)
    • COI: 1:CAS:528:DC%2BC3cXhsFahsLfF, PID: 20679528
    • Hughes TP, Hochhaus A, Branford S, et al. Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS). Blood. 2010;116:3758–65.
    • (2010) Blood , vol.116 , pp. 3758-3765
    • Hughes, T.P.1    Hochhaus, A.2    Branford, S.3
  • 33
    • 84902484777 scopus 로고    scopus 로고
    • ENESTnd update: nilotinib (NIL) vs imatinib (IM) in patients (pts) with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) and the impact of early molecular response (EMR) and Sokal risk at diagnosis on long-term outcomes
    • Saglio G, Hochhaus A, Hughes TP, et al. ENESTnd update: nilotinib (NIL) vs imatinib (IM) in patients (pts) with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) and the impact of early molecular response (EMR) and Sokal risk at diagnosis on long-term outcomes. Blood. 2013;122:92.
    • (2013) Blood , vol.122 , pp. 92
    • Saglio, G.1    Hochhaus, A.2    Hughes, T.P.3
  • 34
    • 77957036311 scopus 로고    scopus 로고
    • Can we and should we improve on frontline imatinib therapy for chronic myeloid leukemia?
    • COI: 1:CAS:528:DC%2BC3cXht1SrurnK, PID: 20875548
    • Fava C, Saglio G. Can we and should we improve on frontline imatinib therapy for chronic myeloid leukemia? Semin Hematol. 2010;47:319–26.
    • (2010) Semin Hematol , vol.47 , pp. 319-326
    • Fava, C.1    Saglio, G.2
  • 35
    • 84904887484 scopus 로고    scopus 로고
    • Prognosis for patients with CML and >10 % BCR-ABL1 after 3 months of imatinib depends on the rate of BCR-ABL1 decline
    • COI: 1:CAS:528:DC%2BC2cXht1Ggu7%2FP, PID: 24859364
    • Branford S, Yeung DT, Parker WT, et al. Prognosis for patients with CML and >10 % BCR-ABL1 after 3 months of imatinib depends on the rate of BCR-ABL1 decline. Blood. 2014;124:511–8.
    • (2014) Blood , vol.124 , pp. 511-518
    • Branford, S.1    Yeung, D.T.2    Parker, W.T.3
  • 36
    • 84921801141 scopus 로고    scopus 로고
    • Velocity of early BCR-ABL transcript elimination as an optimized predictor of outcome in chronic myeloid leukemia (CML) patients in chronic phase on treatment with imatinib
    • COI: 1:CAS:528:DC%2BC2cXptFyksrw%3D, PID: 24798484
    • Hanfstein B, Shlyakhto V, Lauseker M, et al. Velocity of early BCR-ABL transcript elimination as an optimized predictor of outcome in chronic myeloid leukemia (CML) patients in chronic phase on treatment with imatinib. Leukemia. 2014;28:1988–92.
    • (2014) Leukemia , vol.28 , pp. 1988-1992
    • Hanfstein, B.1    Shlyakhto, V.2    Lauseker, M.3
  • 37
    • 84865467990 scopus 로고    scopus 로고
    • Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of BCR-ABL mutations and mutational analysis
    • COI: 1:CAS:528:DC%2BC38Xht1GiurvO, PID: 22920397
    • Soverini S, Martinelli G, Rosti G, Iacobucci I, Baccarani M. Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of BCR-ABL mutations and mutational analysis. Pharmacogenomics. 2012;13:1271–84.
    • (2012) Pharmacogenomics , vol.13 , pp. 1271-1284
    • Soverini, S.1    Martinelli, G.2    Rosti, G.3    Iacobucci, I.4    Baccarani, M.5
  • 38
    • 84890566680 scopus 로고    scopus 로고
    • Implications of BCR-ABL1 kinase domain-mediated resistance in chronic myeloid leukemia
    • COI: 1:CAS:528:DC%2BC3sXhs1Whs7bJ, PID: 24131888
    • Soverini S, Branford S, Nicolini FE, et al. Implications of BCR-ABL1 kinase domain-mediated resistance in chronic myeloid leukemia. Leuk Res. 2014;38:10–20.
    • (2014) Leuk Res , vol.38 , pp. 10-20
    • Soverini, S.1    Branford, S.2    Nicolini, F.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.