메뉴 건너뛰기




Volumn 37, Issue 5, 2014, Pages 161-162

Janus kinase inhibitors in myeloproliferative neoplasms: Clinical applications

Author keywords

Essential thrombocythaemia; Molecular targeted therapy; Myelofibrosis; Polycythaemia vera; Ruxolitinib

Indexed keywords

JANUS KINASE 2 INHIBITOR; MOMELOTINIB; PACRITINIB; PLACEBO; RUXOLITINIB;

EID: 84929922823     PISSN: 03128008     EISSN: None     Source Type: Journal    
DOI: 10.18773/austprescr.2014.063     Document Type: Article
Times cited : (2)

References (11)
  • 1
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, Staerk J, Delhommeau F, Lacout C, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3    Staerk, J.4    Delhommeau, F.5    Lacout, C.6
  • 3
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-61.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3    East, C.4    Fourouclas, N.5    Swanton, S.6
  • 4
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-97.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3    Ebert, B.L.4    Wernig, G.5    Huntly, B.J.6
  • 5
    • 77950684805 scopus 로고    scopus 로고
    • Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: Therapeutic implications for the treatment of myeloproliferative neoplasms
    • Quintas-Cardama A, Vaddi K, Liu P, Manshouri T, Li J, Scherle PA, et al. Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood 2010;115:3109-17.
    • (2010) Blood , vol.115 , pp. 3109-3117
    • Quintas-Cardama, A.1    Vaddi, K.2    Liu, P.3    Manshouri, T.4    Li, J.5    Scherle, P.A.6
  • 8
    • 84875315406 scopus 로고    scopus 로고
    • Long-term outcome of ruxolitinib treatment in patients with myelofibrosis: Durable reductions in spleen volume, improvements in quality of life, and overall survival advantage in COMFORT-I [abstract]
    • Dec 8-11; Atlanta, GA
    • Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, et al. Long-term outcome of ruxolitinib treatment in patients with myelofibrosis: durable reductions in spleen volume, improvements in quality of life, and overall survival advantage in COMFORT-I [abstract]. 54th ASH Annual Meeting and Exposition; 2012 Dec 8-11; Atlanta, GA.
    • (2012) 54th ASH Annual Meeting and Exposition
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3    Levy, R.S.4    Gupta, V.5    Dipersio, J.F.6
  • 9
    • 84875324859 scopus 로고    scopus 로고
    • Long-term safety, efficacy, and survival findings from COMFORT-II, a Phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF) [abstract]
    • Dec 8-11; Atlanta, GA
    • Cervantes F, Kiladjian JJ, Niederwieser D, Sirulnik A, Stalbovskaya V, McQuity M, et al. Long-term safety, efficacy, and survival findings from COMFORT-II, a Phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF) [abstract]. 54th ASH Annual Meeting and Exposition; 2012 Dec 8-11; Atlanta, GA.
    • (2012) 54th ASH Annual Meeting and Exposition
    • Cervantes, F.1    Kiladjian, J.J.2    Niederwieser, D.3    Sirulnik, A.4    Stalbovskaya, V.5    McQuity, M.6
  • 10
    • 84877826630 scopus 로고    scopus 로고
    • Long-term efficacy and safety results from a Phase II study of ruxolitinib in patients with polycythemia vera
    • abstract, Dec 8-11, Atlanta, GA
    • Verstovsek S, Passamonti F, Rambaldi A, Barosi G, Rosen PJ, He S, et al. Long-term efficacy and safety results from a Phase II study of ruxolitinib in patients with polycythemia vera [abstract]. ASH Annual Meeting and Exposition; 2012 Dec 8-11; Atlanta, GA.
    • (2012) ASH Annual Meeting and Exposition
    • Verstovsek, S.1    Passamonti, F.2    Rambaldi, A.3    Barosi, G.4    Rosen, P.J.5    He, S.6
  • 11
    • 84929857795 scopus 로고    scopus 로고
    • Durable responses with the JAK1/JAK2 inhibitor, INCB018424, in patients with polycythemia vera (PV) and essential thrombocythemia (ET) refractory or intolerant to hydroxyurea (HU)
    • abstract, Dec 10-13; Valencia, BC
    • Verstovsek S, Passamonti F, Rambaldi A, Barosi G, Rosen PJ, Levy RA, et al. Durable responses with the JAK1/JAK2 inhibitor, INCB018424, in patients with polycythemia vera (PV) and essential thrombocythemia (ET) refractory or intolerant to hydroxyurea (HU) [abstract]. ASH Annual Meeting and Exposition; 2011 Dec 10-13; Valencia, BC.
    • (2011) ASH Annual Meeting and Exposition
    • Verstovsek, S.1    Passamonti, F.2    Rambaldi, A.3    Barosi, G.4    Rosen, P.J.5    Levy, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.