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Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
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Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: Therapeutic implications for the treatment of myeloproliferative neoplasms
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Quintas-Cardama A, Vaddi K, Liu P, Manshouri T, Li J, Scherle PA, et al. Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood 2010;115:3109-17.
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A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
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Long-term outcome of ruxolitinib treatment in patients with myelofibrosis: Durable reductions in spleen volume, improvements in quality of life, and overall survival advantage in COMFORT-I [abstract]
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Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, et al. Long-term outcome of ruxolitinib treatment in patients with myelofibrosis: durable reductions in spleen volume, improvements in quality of life, and overall survival advantage in COMFORT-I [abstract]. 54th ASH Annual Meeting and Exposition; 2012 Dec 8-11; Atlanta, GA.
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54th ASH Annual Meeting and Exposition
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Verstovsek, S.1
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9
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84875324859
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Long-term safety, efficacy, and survival findings from COMFORT-II, a Phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF) [abstract]
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Dec 8-11; Atlanta, GA
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Cervantes F, Kiladjian JJ, Niederwieser D, Sirulnik A, Stalbovskaya V, McQuity M, et al. Long-term safety, efficacy, and survival findings from COMFORT-II, a Phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF) [abstract]. 54th ASH Annual Meeting and Exposition; 2012 Dec 8-11; Atlanta, GA.
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54th ASH Annual Meeting and Exposition
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Cervantes, F.1
Kiladjian, J.J.2
Niederwieser, D.3
Sirulnik, A.4
Stalbovskaya, V.5
McQuity, M.6
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10
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Long-term efficacy and safety results from a Phase II study of ruxolitinib in patients with polycythemia vera
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abstract, Dec 8-11, Atlanta, GA
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Verstovsek S, Passamonti F, Rambaldi A, Barosi G, Rosen PJ, He S, et al. Long-term efficacy and safety results from a Phase II study of ruxolitinib in patients with polycythemia vera [abstract]. ASH Annual Meeting and Exposition; 2012 Dec 8-11; Atlanta, GA.
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ASH Annual Meeting and Exposition
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Verstovsek, S.1
Passamonti, F.2
Rambaldi, A.3
Barosi, G.4
Rosen, P.J.5
He, S.6
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11
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84929857795
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Durable responses with the JAK1/JAK2 inhibitor, INCB018424, in patients with polycythemia vera (PV) and essential thrombocythemia (ET) refractory or intolerant to hydroxyurea (HU)
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abstract, Dec 10-13; Valencia, BC
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Verstovsek S, Passamonti F, Rambaldi A, Barosi G, Rosen PJ, Levy RA, et al. Durable responses with the JAK1/JAK2 inhibitor, INCB018424, in patients with polycythemia vera (PV) and essential thrombocythemia (ET) refractory or intolerant to hydroxyurea (HU) [abstract]. ASH Annual Meeting and Exposition; 2011 Dec 10-13; Valencia, BC.
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(2011)
ASH Annual Meeting and Exposition
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Verstovsek, S.1
Passamonti, F.2
Rambaldi, A.3
Barosi, G.4
Rosen, P.J.5
Levy, R.A.6
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