Nanocomposite hydrogels: An emerging biomimetic platform for myocardial therapy and tissue engineering

Nanomedicine

Volumn 10, Issue 9, 2015, Pages 1371-1374

  Paul, Arghya ^a  

^a University of Kansas   (United States)

Author keywords

cardiovascular therapy; hydrogel; nanohybrids; regenerative medicine; tissue engineering

Indexed keywords

CARBON NANOTUBE; MATRIX METALLOPROTEINASE; NANOCARRIER; NANOCOMPOSITE; NANOPARTICLE; NANOWIRE; POLYMER; VASCULOTROPIN; HYDROGEL;

ANGIOGENESIS; BIOCOMPATIBILITY; BIOMIMETICS; CYTOLOGY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RESISTANCE; DRUG STABILITY; EDITORIAL; ELECTROSTIMULATION; ENZYME INHIBITION; EXCITATION CONTRACTION COUPLING; EXTRACELLULAR MATRIX; HEART FUNCTION; HEART INFARCTION; HEART PROTECTION; HUMAN; HYDROGEL; MECHANICAL STIMULATION; MEDICAL PRACTICE; PERSONALIZED MEDICINE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SUBSTITUTION THERAPY; TISSUE ENGINEERING; TISSUE INJURY; TISSUE REPAIR; CARDIOMYOPATHIES; MINIATURIZATION;

BIOMIMETICS; CARDIOMYOPATHIES; HUMANS; HYDROGELS; MINIATURIZATION; NANOCOMPOSITES; TISSUE ENGINEERING;

EID: 84929861434     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.15.33     Document Type: Editorial

References (20)

1. Go AS, Mozaffarian D, Roger VL et al. Heart disease and stroke statistics - 2013 update: a report from the American Heart Association. Circulation 127(1), e6-e245 (2013).
2. Chong JJ, Yang X, Don CW et al. Human embryonic-stemcell-derived cardiomyocytes regenerate non-human primate hearts. Nature 510(7504), 273-277 (2014).
3. Paul A, Ge Y, Prakash S, Shum-Tim D. Microencapsulated stem cells for tissue repairing: implications in cell-based myocardial therapy. Regen. Med. 4(5), 733-745 (2009).
4. Donaldson K, Duffin R, Langrish JP et al. Nanoparticles and the cardiovascular system: a critical review. Nanomedicine 8(3), 403-423 (2013).
5. Chang MY, Yang YJ, Chang CH et al. Functionalized nanoparticles provide early cardioprotection after acute myocardial infarction. J. Control. Release 170(2), 287-294 (2013).
6. Zsebo K, Yaroshinsky A, Rudy JJ et al. Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality. Circ. Res. 114(1), 101-108 (2014).
7. Paul A, Hasan A, Rodes L, Sangaralingam M, Prakash S. Bioengineered baculoviruses as new class of therapeutics using micro and nanotechnologies: principles, prospects and challenges. Adv. Drug Deliv. Rev. 71, 115-130 (2014).
8. Harel-Adar T, Ben Mordechai T, Amsalem Y, Feinberg MS, Leor J, Cohen S. Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair. Proc. Natl Acad. Sci. USA 108(5), 1827-1832 (2011).
9. Seif-Naraghi SB, Singelyn JM, Salvatore MA et al. Safety and efficacy of an injectable extracellular matrix hydrogel for treating myocardial infarction. Sci. Transl. Med. 5(173), 173ra125 (2013).
10. Paul A, Hasan A, Kindi HA et al. Injectable graphene oxide/hydrogel-based angiogenic gene delivery system for vasculogenesis and cardiac repair. ACS Nano 8(8), 8050-8062 (2014).
11. Gaharwar AK, Avery RK, Assmann A et al. Shear-thinning nanocomposite hydrogels for the treatment of hemorrhage. ACS Nano 8(10), 9833-9842 (2014).
12. Wong Po Foo CT, Lee JS, Mulyasasmita W, Parisi-Amon A, Heilshorn SC. Two-component protein-engineered physical hydrogels for cell encapsulation. Proc. Natl Acad. Sci. USA 106(52), 22067-22072 (2009).
13. Purcell BP, Lobb D, Charati MB et al. Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition. Nat. Mater. 13(6), 653-661 (2014).
14. Li Z, Guo X, Guan J. An oxygen release system to augment cardiac progenitor cell survival and differentiation under hypoxic condition. Biomaterials 33(25), 5914-5923 (2012).
15. Oh KS, Song JY, Yoon SJ, Park Y, Kim D, Yuk SH. Temperature-induced gel formation of core/shell nanoparticles for the regeneration of ischemic heart. J. Control. Release 146(2), 207-211 (2010).
16. Bhatia SN, Ingber DE. Microfluidic organs-on-chips. Nat. Biotechnol. 32(8), 760-772 (2014).
17. Agarwal A, Goss JA, Cho A, Mccain ML, Parker KK. Microfluidic heart on a chip for higher throughput pharmacological studies. Lab Chip 13(18), 3599-3608 (2013).
18. Shin SR, Jung SM, Zalabany M et al. Carbon-nanotube-embedded hydrogel sheets for engineering cardiac constructs and bioactuators. ACS Nano 7(3), 2369-2380 (2013).
19. Shevach M, Fleischer S, Shapira A, Dvir T. Gold nanoparticle-decellularized matrix hybrids for cardiac tissue engineering. Nano Lett. 14(10), 5792-5796 (2014).
20. Dvir T, Timko BP, Brigham MD et al. Nanowired three-dimensional cardiac patches. Nat. Nanotechnol. 6(11), 720-725 (2011).