Concise Review: The Role of Oxygen in Hematopoietic Stem Cell Physiology

Journal of Cellular Physiology

Volumn 230, Issue 9, 2015, Pages 1999-2005

  Jež, Mojca ^a   Rožman, Primož ^a   Ivanović, Zoran ^b   Bas, Tuba ^c  

^a Department of Immunohematology Blood Transfusion Centre of Slovenia   (Slovakia)

^b CNRS Bordeaux Segalen University   (France)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN;

ADULT STEM CELL; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; ENERGY METABOLISM; HEMATOPOIETIC STEM CELL; HUMAN; IN VIVO STUDY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN TENSION; PH; PRIORITY JOURNAL; REVIEW; STEM CELL NICHE; TEMPERATURE; CULTURE TECHNIQUE; METABOLISM; PHYSIOLOGY; TISSUE ENGINEERING;

ADULT STEM CELLS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; HEMATOPOIETIC STEM CELLS; HUMANS; OXYGEN; STEM CELL NICHE; TISSUE ENGINEERING;

EID: 84929773811     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24953     Document Type: Review

References (51)

1. Ben-Porath I, Weinberg RA. 2004. When cells get stressed: An integrative view of cellular senescence. J Clin Invest 113:8-13.
2. Brunet De La Grange P, Barthe C, Lippert E, Hermitte F, Belloc F, Lacombe F, Ivanovic Z, Praloran V. 2006. Oxygen concentration influences mRNA processing and expression of the cd34 gene. JCB 97:135-144.
3. Calvi LM, Link DC. 2014. Cellular complexity of the bone marrow hematopoietic stem cell niche. Calcif Tissue Int 94:112-124.
4. Cheshier SH, Morrison SJ, Liao X, Weissman IL. 1999. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci USA 96:3120-3125.
5. Chien S. 2000. Metabolic management. Austin, TX: Landes Bioscience. 81 p.
6. Chow DC, Wenning LA, Miller WM, Papoutsakis ET. 2001. Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models. Biophys J 81:685-696.
7. Dhimitruka I, Bobko AA, Eubank TD, Komarov DA, Khramtsov VV. 2013. Phosphonated trityl probes for concurrent in vivo tissue oxygen and pH monitoring using electron paramagnetic resonance-based techniques. J Am Chem Soc 135:5904-5910.
8. Eliasson P, Jönsson J-I. 2010. The hematopoietic stem cell niche: Low in oxygen but a nice place to be. J Cell Physiol 222:17-22.
9. Eliasson P, Rehn M, Hammar P, Larsson P, Sirenko O, Flippin LA, Cammenga J, Jönsson J-I. 2010. Hypoxia mediates low cell-cycle activity and increases the proportion of long-term-reconstituting hematopoietic stem cells during in vitro culture. Exp Hematol 38:301-310.e2.
10. 2 tensions and the prevention of differentiation of hES cells. Proc Natl Acad Sci USA 102:4783-4788.
11. Frei R, Gaucher C, Poulton SW, Canfield DE. 2009. Fluctuations in Precambrian atmospheric oxygenation recorded by chromium isotopes. Nature 461:250-253.
12. Harrison JS, Rameshwar P, Chang V, Bandari P. 2002. Oxygen saturation in the bone marrow of healthy volunteers. Blood 99:394.
13. Hemphill JC, Smith WS, Sonne DC, Morabito D, Manley GT. 2005. Relationship between brain tissue oxygen tension and CT perfusion: Feasibility and initial results. AJNR Am J Neuroradiol 26:1095-1100.
14. 2 concentration (0.1%) favors G0 return of dividing CD34+ cells. Stem Cells 24:65-73.
15. Holland HD. 2006. The oxygenation of the atmosphere and oceans. Philos Trans R Soc B 361:903-915.
16. Ivanovic Z. 2009a. Hypoxia or in situ normoxia: The stem cell paradigm. J Cell Physiol 219:271-275.
17. Ivanovic Z. 2009b. Oxygen availability and self renewal of stem cells. In: Stoica A, Arslan T, Huntsberger T, Botez P, Erdogan AT, El-Rayis AO, editors. Advanced technologies for enhanced quality of life. Los Alamitos, CA: IEEE Computer Society Press. pp 73-76.
18. Ivanovic Z. 2010. Hematopoietic stem cells in research and clinical applications: The "CD34 issue". World J Stem Cells 2:18-23.
19. Ivanovic Z. 2013. Respect the anaerobic nature of stem cells to exploit their potential in regenerative medicine. Regen Med 8:677-680.
20. 2 concentration (3%). Stem Cells 22:716-724.
21. Jeanne M, Kovacevic-Filipovic M, Szyporta M, Vlaski M, Hermitte F, Lafarge X, Duchez P, Boiron JM, Praloran V, Ivanovic Z. 2009. Low-oxygen and high-carbon-dioxide atmosphere improves the conservation of hematopoietic progenitors in hypothermia. Transfusion 49:1738-1746.
22. Kaewsuwan S, Song SY, Kim JH, Sung J-H. 2012. Mimicking the functional niche of adipose-derived stem cells for regenerative medicine. Expert Opin Biol Ther 12:1575-1588.
23. Kodama S, Mori I, Roy K, Yang Z, Suzuki K, Watanabe M. 2001. Culture condition-dependent senescence-like growth arrest and immortalization in rodent embryo cells. Radiat Res 155:254-262.
24. Kunisaki Y, Bruns I, Scheiermann C, Ahmed J, Pinho S, Zhang D, Mizoguchi T, Wei Q, Lucas D, Ito K, Mar JC, Bergman A, Frenette PS. 2013. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature 502:637-643.
25. Kunisaki Y, Frenette PS. 2014. Influences of vascular niches on hematopoietic stem cell fate. Int J Hematol 99:699-705.
26. Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T. 2012. What does the concept of the stem cell niche really mean today? BMC Biol 10:19.
27. Latil M, Rocheteau P, Châtre L, Sanulli S, Mémet S, Ricchetti M, Tajbakhsh S, Chrétien F. 2012. Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity. Nat Commun 3:903.
28. Lévesque J-P, Winkler IG. 2011. Hierarchy of immature hematopoietic cells related to blood flow and niche. Curr Opin Hematol 18:220-225.
29. Li L, Xie T. 2005. Stem cell niche: Structure and function. Annu Rev Cell Dev Biol 21:605-631.
30. Ma T, Grayson WL, Fröhlich M, Vunjak-Novakovic G. 2009. Hypoxia and stem cell-based engineering of mesenchymal tissues. Biotechnol Prog 25:32-42.
31. Matsumoto A, Matsumoto S, Sowers AL, Koscielniak JW, Trigg NJ, Kuppusamy P, Mitchell JB, Subramanian S, Krishna MC, Matsumoto K. 2005. Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR. Magn Reson Med 54:1530-1535.
32. Mohyeldin A, Garzón-Muvdi T, Quiñones-Hinojosa A. 2010. Oxygen in stem cell biology: A critical component of the stem cell niche. Cell Stem Cell 7:150-161.
33. Moussavi-Harami F, Duwayri Y, Martin JA, Moussavi-Harami F, Buckwalter JA. 2004. Oxygen effects on senescence in chondrocytes and mesenchymal stem cells: Consequences for tissue engineering. Iowa Orthop J 24:15-20.
34. Närvä E, Pursiheimo J-P, Laiho A, Rahkonen N, Emani MR, Viitala M, Laurila K, Sahla R, Lund R, Lähdesmäki H, Jaakkola P, Lahesmaa R. 2013. Continuous hypoxic culturing of human embryonic stem cells enhances SSEA-3 and MYC levels. PloS ONE 8:e78847.
35. Nilsson SK, Johnston HM, Coverdale JA. 2001. Spatial localization of transplanted hemopoietic stem cells: Inferences for the localization of stem cell niches. Blood 97:2293-2299.
36. Nombela-Arrieta C, Pivarnik G, Winkel B, Canty KJ, Harley B, Mahoney JE, Park SY, Lu J, Protopopov A, Silberstein LE. 2013. Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment. Nat Cell Biol 15:533-543.
37. Parmar K, Mauch P, Vergilio JA, Sackstein R, Down JD. 2007. Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc Natl Acad Sci USA 104:5431-5436.
38. Piccoli C, D'Aprile A, Ripoli M, Scrima R, Boffoli D, Tabilio A, Capitanio N. 2007. The hypoxia-inducible factor is stabilized in circulating hematopoietic stem cells under normoxic conditions. FEBS Lett 581:3111-3119.
39. Pollard PJ, Kranc KR. 2010. Hypoxia signaling in hematopoietic stem cells: A double-edged sword. Cell Stem Cell 7:276-278.
40. Rodesch F, Simon P, Donner C, Jauniaux E. 1992. Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet Gynecol 80:283-285.
41. Roy S, Tripathy M, Mathur N, Jain A, Mukhopadhyay A. 2012. Hypoxia improves expansion potential of human cord blood-derived hematopoietic stem cells and marrow repopulation efficiency. Eur J Haematol 88:396-405.
42. Schofield R. 1978. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4:7-25.
43. Simon MC, Keith B. 2008. The role of oxygen availability in embryonic development and stem cell function. Nat Rev Mol Cell Biol 9:285-296.
44. Simsek T, Kocabas F, Zheng J, Deberardinis RJ, Mahmoud AI, Olson EN, Schneider JW, Zhang CC, Sadek HA. 2010. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell 7:380-390.
45. Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T. 2010. Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell 7:391-402.
46. 2 and pH in the anaesthetized dog. Acta Orthop Scand 50:645-651.
47. Vlaski M, Lafarge X, Chevaleyre J, Duchez P, Boiron JM, Ivanovic Z. 2009. Low oxygen concentration as a general physiologic regulator of erythropoiesis beyond the EPO-related downstream tuning and a tool for the optimization of red blood cell production ex vivo. Exp Hematol 37:573-584.
48. Vlaski M, Negroni L, Kovacevic-Filipovic M, Guibert C, Brunet de la Grange P, Rossignol R, Chevaleyre J, Duchez P, Lafarge X, Praloran V, Schmitter JM, Ivanovic Z. 2014. Hypoxia/hypercapnia-induced adaptation maintains functional capacity of cord blood stem and progenitor cells at 4°C. J Cell Physiol 229:2153-2165.
49. Winkler IG, Barbier V, Wadley R, Zannettino ACW, Williams S, Lévesque J-P. 2010. Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches. Blood 116:375-385.
50. Zachar V, Duroux M, Emmersen J, Rasmussen JG, Pennisi CP, Yang S, Fink T. 2011. Hypoxia and adipose-derived stem cell-based tissue regeneration and engineering. Expert Opin Biol Ther 11:775-786.
51. Zhang J, Niu C, Ye L, Huang H, He X, Tong W-G, Ross J, Haug J, Johnson T, Feng JQ, Harris S, Wiedemann LM, Mishina Y, Li L. 2003. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425:836-841.