-
1
-
-
84873956600
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
Vestbo J, Hurd SS, Agustí AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013;187(4):347-65
-
(2013)
Am J Respir Crit Care Med
, vol.187
, Issue.4
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agustí, A.G.3
-
2
-
-
39049170984
-
Global strategy for asthma management and prevention: GINA executive summary
-
Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31(1):143-78
-
(2008)
Eur Respir J
, vol.31
, Issue.1
, pp. 143-178
-
-
Bateman, E.D.1
Hurd, S.S.2
Barnes, P.J.3
-
3
-
-
84892590856
-
Antibodies to watch in 2014
-
Reichert JM. Antibodies to watch in 2014. mAbs 2014;6(1):5-14
-
(2014)
MAbs
, vol.6
, Issue.1
, pp. 5-14
-
-
Reichert, J.M.1
-
4
-
-
84903581591
-
Antibodies to watch in 2014: Mid-year update
-
Reichert JM. Antibodies to watch in 2014: mid-year update. mAbs 2014;6(4):799-802
-
(2014)
MAbs
, vol.6
, Issue.4
, pp. 799-802
-
-
Reichert, J.M.1
-
5
-
-
33744498618
-
Pharmacokinetics of intravenous immunoglobulin: A systematic review
-
Koleba T, Ensom MH. Pharmacokinetics of intravenous immunoglobulin: A systematic review. Pharmacotherapy 2006;26(6):813-27
-
(2006)
Pharmacotherapy
, vol.26
, Issue.6
, pp. 813-827
-
-
Koleba, T.1
Ensom, M.H.2
-
6
-
-
17844393640
-
Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys
-
Hart TK, Cook RM, Zia-Amirhosseini P, et al. Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys. J Allergy Clin Immunol 2001;108(2):250-7
-
(2001)
J Allergy Clin Immunol
, vol.108
, Issue.2
, pp. 250-257
-
-
Hart, T.K.1
Cook, R.M.2
Zia-Amirhosseini, P.3
-
7
-
-
33747631571
-
Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn
-
DallAcqua WF, Kiener PA, Wu H. Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn). J Biol Chem 2006;281(33):23514-24
-
(2006)
J Biol Chem
, vol.281
, Issue.33
, pp. 23514-23524
-
-
Dallacqua, W.F.1
Kiener, P.A.2
Wu, H.3
-
8
-
-
77950517325
-
The safety and side effects of monoclonal antibodies
-
Hansel TT, Kropshofer H, Singer T, et al. The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov 2010;9(4):325-38
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.4
, pp. 325-338
-
-
Hansel, T.T.1
Kropshofer, H.2
Singer, T.3
-
9
-
-
43049090854
-
Aerodynamical, immunological and pharmacological properties of the anticancer antibody cetuximab following nebulization
-
Maillet A, Congy-Jolivet N, Le Guellec S, et al. Aerodynamical, immunological and pharmacological properties of the anticancer antibody cetuximab following nebulization. Pharm Res 2008;25(6):1318-26
-
(2008)
Pharm Res
, vol.25
, Issue.6
, pp. 1318-1326
-
-
Maillet, A.1
Congy-Jolivet, N.2
Le Guellec, S.3
-
10
-
-
84913587762
-
Effect of formulation on the stability and aerosol performance of a nebulized antibody
-
Respaud R, Marchand D, Parent C, et al. Effect of formulation on the stability and aerosol performance of a nebulized antibody. mAbs 2014;6(5):1347-55
-
(2014)
MAbs
, vol.6
, Issue.5
, pp. 1347-1355
-
-
Respaud, R.1
Marchand, D.2
Parent, C.3
-
11
-
-
84872849087
-
The discovery, engineering and characterisation of a highly potent antihuman IL-13 fab fragment designed for administration by inhalation
-
Lightwood D, ODowd V, Carrington B, et al. The discovery, engineering and characterisation of a highly potent antihuman IL-13 fab fragment designed for administration by inhalation. J Mol Biol 2013;425(3):577-93
-
(2013)
J Mol Biol
, vol.425
, Issue.3
, pp. 577-593
-
-
Lightwood, D.1
Odowd, V.2
Carrington, B.3
-
12
-
-
2942635256
-
Paul Ehrlich -in search of the magic bullet
-
Winau F, Westphal O, Winau R. Paul Ehrlich -in search of the magic bullet. Microbes Infect 2004;6(8):786-9
-
(2004)
Microbes Infect
, vol.6
, Issue.8
, pp. 786-789
-
-
Winau, F.1
Westphal, O.2
Winau, R.3
-
13
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Köhler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975;256(5517):495-7
-
(1975)
Nature
, vol.256
, Issue.5517
, pp. 495-497
-
-
Köhler, G.1
Milstein, C.2
-
14
-
-
0022355587
-
Human immune response to multiple injections of murine monoclonal IgG
-
Shawler DL, Bartholomew RM, Smith LM, Dillman RO. Human immune response to multiple injections of murine monoclonal IgG. J Immunol 1985;135(2):1530-5
-
(1985)
J Immunol
, vol.135
, Issue.2
, pp. 1530-1535
-
-
Shawler, D.L.1
Bartholomew, R.M.2
Smith, L.M.3
Dillman, R.O.4
-
15
-
-
78649642694
-
Have we overestimated the benefit of human(ized) antibodies?
-
Getts DR, Getts MT, McCarthy DP, et al. Have we overestimated the benefit of human(ized) antibodies? mAbs 2010;2(6):682-94
-
(2010)
MAbs
, vol.2
, Issue.6
, pp. 682-694
-
-
Getts, D.R.1
Getts, M.T.2
McCarthy, D.P.3
-
16
-
-
0021713342
-
Production of functional chimaeric mouse/human antibody
-
Boulianne GL, Hozumi N, Shulman MJ. Production of functional chimaeric mouse/human antibody. Nature 1984;312(5995):643-6
-
(1984)
Nature
, vol.312
, Issue.5995
, pp. 643-646
-
-
Boulianne, G.L.1
Hozumi, N.2
Shulman, M.J.3
-
17
-
-
0022558297
-
Replacing the complementaritydetermining regions in a human antibody with those from a mouse
-
Jones PT, Dear PH, Foote J, et al. Replacing the complementaritydetermining regions in a human antibody with those from a mouse. Nature 1986;321(6069):522-5
-
(1986)
Nature
, vol.321
, Issue.6069
, pp. 522-525
-
-
Jones, P.T.1
Dear, P.H.2
Foote, J.3
-
18
-
-
30344484440
-
Antibody engineering for the development of therapeutic antibodies
-
Kim SJ, Park Y, Hong HJ. Antibody engineering for the development of therapeutic antibodies. Mol Cells 2005;20(1):17-29
-
(2005)
Mol Cells
, vol.20
, Issue.1
, pp. 17-29
-
-
Kim, S.J.1
Park, Y.2
Hong, H.J.3
-
20
-
-
0142087554
-
Antibodies as therapeutic agents: Vive la renaissance!
-
Stockwin LH, Holmes S. Antibodies as therapeutic agents: vive la renaissance!. Expert Opin Biol Ther 2003;3(7):1133-52
-
(2003)
Expert Opin Biol Ther
, vol.3
, Issue.7
, pp. 1133-1152
-
-
Stockwin, L.H.1
Holmes, S.2
-
21
-
-
38449084690
-
Historical development of monoclonal antibody therapeutics
-
Nissim A, Chernajovsky Y. Historical development of monoclonal antibody therapeutics. Handb Exp Pharmacol 2008(181):3-18
-
(2008)
Handb Exp Pharmacol
, vol.181
, pp. 3-18
-
-
Nissim, A.1
Chernajovsky, Y.2
-
24
-
-
78651360674
-
Optimizing therapeutic antibody function: Progress with Fc domain engineering
-
Kaneko E, Niwa R. Optimizing therapeutic antibody function: progress with Fc domain engineering. BioDrugs 2011;25(1):1-11
-
(2011)
BioDrugs
, vol.25
, Issue.1
, pp. 1-11
-
-
Kaneko, E.1
Niwa, R.2
-
25
-
-
78751524881
-
Interindividual variability of response to rituximab: From biological origins to individualized therapies
-
Cartron G, Trappe RU, Solal-Celigny P, Hallek M. Interindividual variability of response to rituximab: from biological origins to individualized therapies. Clin Cancer Res 2011;17(1):19-30
-
(2011)
Clin Cancer Res
, vol.17
, Issue.1
, pp. 19-30
-
-
Cartron, G.1
Trappe, R.U.2
Solal-Celigny, P.3
Hallek, M.4
-
26
-
-
1342345215
-
Complement function in mAb-mediated cancer immunotherapy
-
Gelderman KA, Tomlinson S, Ross GD, Gorter A. Complement function in mAb-mediated cancer immunotherapy. Trends Immunol 2004;25(3):158-64
-
(2004)
Trends Immunol
, vol.25
, Issue.3
, pp. 158-164
-
-
Gelderman, K.A.1
Tomlinson, S.2
Ross, G.D.3
Gorter, A.4
-
27
-
-
0036255688
-
Targeted therapy of cancer with radiolabeled antibodies
-
Goldenberg DM. Targeted therapy of cancer with radiolabeled antibodies. J Nucl Med 2002;43(5):693-713
-
(2002)
J Nucl Med
, vol.43
, Issue.5
, pp. 693-713
-
-
Goldenberg, D.M.1
-
28
-
-
84856120429
-
Monoclonal antibodies: What are the pharmacokinetic and pharmacodynamic considerations for drug development?
-
Deng R, Jin F, Prabhu S, Iyer S. Monoclonal antibodies: what are the pharmacokinetic and pharmacodynamic considerations for drug development? Expert Opin Drug Metab Toxicol 2012;8(2):141-60
-
(2012)
Expert Opin Drug Metab Toxicol
, vol.8
, Issue.2
, pp. 141-160
-
-
Deng, R.1
Jin, F.2
Prabhu, S.3
Iyer, S.4
-
29
-
-
77954472838
-
Clinical pharmacokinetics of therapeutic monoclonal antibodies
-
Keizer RJ, Huitema AD, Schellens JH, Beijnen JH. Clinical pharmacokinetics of therapeutic monoclonal antibodies. Clin Pharmacokinet 2010;49(8):493-507
-
(2010)
Clin Pharmacokinet
, vol.49
, Issue.8
, pp. 493-507
-
-
Keizer, R.J.1
Huitema, A.D.2
Schellens, J.H.3
Beijnen, J.H.4
-
30
-
-
74749088334
-
Pharmacokinetics (PK) of mAbs]
-
Paintaud G. [Pharmacokinetics (PK) of mAbs]. Med Sci(Paris) 2009;25(12):1057-62
-
(2009)
Med Sci(Paris)
, vol.25
, Issue.12
, pp. 1057-1062
-
-
Paintaud, G.1
-
31
-
-
17644378667
-
Immunogenicity of engineered antibodies
-
Hwang WY, Foote J. Immunogenicity of engineered antibodies. Methods 2005;36(1):3-10
-
(2005)
Methods
, vol.36
, Issue.1
, pp. 3-10
-
-
Hwang, W.Y.1
Foote, J.2
-
32
-
-
78651340524
-
Neonatal Fc receptor: From immunity to therapeutics
-
Kuo TT, Baker K, Yoshida M, et al. Neonatal Fc receptor: from immunity to therapeutics. J Clin Immunol 2010;30(6):777-89
-
(2010)
J Clin Immunol
, vol.30
, Issue.6
, pp. 777-789
-
-
Kuo, T.T.1
Baker, K.2
Yoshida, M.3
-
33
-
-
0036902323
-
Immunoglobulin transport across polarized epithelial cells
-
Rojas R, Apodaca G. Immunoglobulin transport across polarized epithelial cells. Nat Rev Mol Cell Biol 2002;3(12):944-55
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, Issue.12
, pp. 944-955
-
-
Rojas, R.1
Apodaca, G.2
-
34
-
-
69949115639
-
Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn
-
Ward ES, Ober RJ. Chapter 4: multitasking by exploitation of intracellular transport functions the many faces of FcRn. Adv Immunol 2009;103:77-115
-
(2009)
Adv Immunol
, vol.103
, pp. 77-115
-
-
Ward, E.S.1
Ober, R.J.2
-
35
-
-
77951294518
-
An intracellular traffic jam: Fc receptor-mediated transport of immunoglobulin G
-
Tesar DB, Björkman PJ. An intracellular traffic jam: fc receptor-mediated transport of immunoglobulin G. Curr Opin Struct Biol 2010;20(2):226-33
-
(2010)
Curr Opin Struct Biol
, vol.20
, Issue.2
, pp. 226-233
-
-
Tesar, D.B.1
Björkman, P.J.2
-
36
-
-
0037025895
-
Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: Functional expression of FcRn in the mammalian lung
-
Spiekermann GM, Finn PW, Ward ES, et al. Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung. J Exp Med 2002;196(3):303-10
-
(2002)
J Exp Med
, vol.196
, Issue.3
, pp. 303-310
-
-
Spiekermann, G.M.1
Finn, P.W.2
Ward, E.S.3
-
37
-
-
3042795848
-
Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway
-
Bitonti AJ, Dumont JA, Low SC, et al. Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway. Proc Natl Acad Sci USA 2004;101(26):9763-8
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.26
, pp. 9763-9768
-
-
Bitonti, A.J.1
Dumont, J.A.2
Low, S.C.3
-
38
-
-
25844528107
-
Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway
-
Dumont JA, Bitonti AJ, Clark D, et al. Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway. J Aerosol Med 2005;18(3):294-303
-
(2005)
J Aerosol Med
, vol.18
, Issue.3
, pp. 294-303
-
-
Dumont, J.A.1
Bitonti, A.J.2
Clark, D.3
-
39
-
-
32544438613
-
Expression and transport functionality of FcRn within rat alveolar epithelium: A study in primary cell culture and in the isolated perfused lung
-
Sakagami M, Omidi Y, Campbell L, et al. Expression and transport functionality of FcRn within rat alveolar epithelium: A study in primary cell culture and in the isolated perfused lung. Pharm Res 2006;23(2):270-9
-
(2006)
Pharm Res
, vol.23
, Issue.2
, pp. 270-279
-
-
Sakagami, M.1
Omidi, Y.2
Campbell, L.3
-
40
-
-
54249138516
-
Monoclonal antibody pharmacokinetics and pharmacodynamics
-
Wang W, Wang EQ, Balthasar JP. Monoclonal antibody pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther 2008;84(5):548-58
-
(2008)
Clin Pharmacol Ther
, vol.84
, Issue.5
, pp. 548-558
-
-
Wang, W.1
Wang, E.Q.2
Balthasar, J.P.3
-
42
-
-
4143071295
-
Net absorption of IgG via FcRnmediated transcytosis across rat alveolar epithelial cell monolayers
-
Kim K-J, Fandy TE, Lee VHL, et al. Net absorption of IgG via FcRnmediated transcytosis across rat alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol 2004;287(3):L616-22
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
, Issue.3
, pp. L616-L622
-
-
Kim, K.-J.1
Fandy, T.E.2
Vhl, L.3
-
43
-
-
80054750755
-
The airways a novel route for delivering monoclonal antibodies to treat lung tumors
-
Maillet A, Guilleminault L, Lemarie E, et al. The airways, a novel route for delivering monoclonal antibodies to treat lung tumors. Pharm Res 2011;28(9):2147-56
-
(2011)
Pharm Res
, vol.28
, Issue.9
, pp. 2147-2156
-
-
Maillet, A.1
Guilleminault, L.2
Lemarie, E.3
-
44
-
-
84920754881
-
VEGF neutralizing aerosol therapy in primary pulmonary adenocarcinoma with K-ras activating-mutations
-
Rabbe N, Guilleminault L, Paul F, et al. VEGF neutralizing aerosol therapy in primary pulmonary adenocarcinoma with K-ras activating-mutations. mAbs 2014;6(6):1638-48
-
(2014)
MAbs
, vol.6
, Issue.6
, pp. 1638-1648
-
-
Rabbe, N.1
Guilleminault, L.2
Paul, F.3
-
45
-
-
84873362213
-
Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice
-
Kliwinski C, Cooper PR, Perkinson R, et al. Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice. Am J Physiol Gastrointest Liver Physiol 2013;304(3):G262-70
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, Issue.3
, pp. G262-G270
-
-
Kliwinski, C.1
Cooper, P.R.2
Perkinson, R.3
-
46
-
-
84902096251
-
PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract
-
Koussoroplis SJ, Paulissen G, Tyteca D, et al. PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract. J Control Release 2014;187:91-100
-
(2014)
J Control Release
, vol.187
, pp. 91-100
-
-
Koussoroplis, S.J.1
Paulissen, G.2
Tyteca, D.3
-
47
-
-
84910020975
-
Fate of inhaled monoclonal antibodies after the deposition of aerosolized particles in the respiratory system
-
Guilleminault L, Azzopardi N, Arnoult C, et al. Fate of inhaled monoclonal antibodies after the deposition of aerosolized particles in the respiratory system. J Control Release 2014;196:344-54
-
(2014)
J Control Release
, vol.196
, pp. 344-354
-
-
Guilleminault, L.1
Azzopardi, N.2
Arnoult, C.3
-
48
-
-
1842656196
-
Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules
-
Lombry C, Edwards DA, Preat V, Vanbever R. Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules. Am J Physiol Lung Cell Mol Physiol 2004;286(5):L1002-8
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.286
, Issue.5
, pp. L1002-L1008
-
-
Lombry, C.1
Edwards, D.A.2
Preat, V.3
Vanbever, R.4
-
49
-
-
17744376022
-
Anti-immunoglobulin e treatment with omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy
-
Holgate ST, Djukanović R, Casale T, Bousquet J. Anti-immunoglobulin E treatment with omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy. Clin Exp Allergy 2005;35(4):408-16
-
(2005)
Clin Exp Allergy
, vol.35
, Issue.4
, pp. 408-416
-
-
Holgate, S.T.1
Djukanović, R.2
Casale, T.3
Bousquet, J.4
-
50
-
-
79961127439
-
Can anti-IgE therapy prevent airway remodeling in allergic asthma?
-
Rabe KF, Calhoun WJ, Smith N, Jimenez P. Can anti-IgE therapy prevent airway remodeling in allergic asthma? Allergy 2011;66(9):1142-51
-
(2011)
Allergy
, vol.66
, Issue.9
, pp. 1142-1151
-
-
Rabe, K.F.1
Calhoun, W.J.2
Smith, N.3
Jimenez, P.4
-
51
-
-
14844300188
-
The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation
-
Holgate S, Casale T, Wenzel S, et al. The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation. J Allergy Clin Immunol 2005;115(3):459-65
-
(2005)
J Allergy Clin Immunol
, vol.115
, Issue.3
, pp. 459-465
-
-
Holgate, S.1
Casale, T.2
Wenzel, S.3
-
53
-
-
1542404791
-
Rational design of solid aerosols for immunoglobulin delivery by modulation of aerodynamic and release characteristics
-
Dellamary L, Smith DJ, Bloom A, et al. Rational design of solid aerosols for immunoglobulin delivery by modulation of aerodynamic and release characteristics. J Control Release 2004;95(3):489-500
-
(2004)
J Control Release
, vol.95
, Issue.3
, pp. 489-500
-
-
Dellamary, L.1
Smith, D.J.2
Bloom, A.3
-
54
-
-
36649033018
-
Conformational analysis of protein secondary structure during spraydrying of antibody/mannitol formulations
-
Schüle S, Friess W, Bechtold-Peters K, Garidel P. Conformational analysis of protein secondary structure during spraydrying of antibody/mannitol formulations. Eur J Pharm Biopharm 2007;65(1):1-9
-
(2007)
Eur J Pharm Biopharm
, vol.65
, Issue.1
, pp. 1-9
-
-
Schüle, S.1
Friess, W.2
Bechtold-Peters, K.3
Garidel, P.4
-
55
-
-
12344290280
-
Spray-drying of proteins: Effects of sorbitol and trehalose on aggregation and FT-IR amide i spectrum of an immunoglobulin G
-
Maury M, Murphy K, Kumar S, et al. Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G. Eur J Pharm Biopharm 2005;59(2):251-61
-
(2005)
Eur J Pharm Biopharm
, vol.59
, Issue.2
, pp. 251-261
-
-
Maury, M.1
Murphy, K.2
Kumar, S.3
-
56
-
-
54949157652
-
Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients
-
Minne A, Boireau H, Horta MJ, Vanbever R. Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients. Eur J Pharm Biopharm 2008;70(3):839-44
-
(2008)
Eur J Pharm Biopharm
, vol.70
, Issue.3
, pp. 839-844
-
-
Minne, A.1
Boireau, H.2
Horta, M.J.3
Vanbever, R.4
-
57
-
-
33745658916
-
Prospects of formulating proteins/peptides as aerosols for pulmonary drug delivery
-
Shoyele SA, Slowey A. Prospects of formulating proteins/peptides as aerosols for pulmonary drug delivery. Int J Pharm 2006;314(1):1-8
-
(2006)
Int J Pharm
, vol.314
, Issue.1
, pp. 1-8
-
-
Shoyele, S.A.1
Slowey, A.2
-
58
-
-
0032962882
-
The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody
-
Andya JD, Maa YF, Costantino HR, et al. The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody. Pharm Res 1999;16(3):350-8
-
(1999)
Pharm Res
, vol.16
, Issue.3
, pp. 350-358
-
-
Andya, J.D.1
Maa, Y.F.2
Costantino, H.R.3
-
59
-
-
33846140780
-
Antibody structure, instability, and formulation
-
Wang W, Singh S, Zeng DL, et al. Antibody structure, instability, and formulation. J Pharm Sci 2007;96(1):1-26
-
(2007)
J Pharm Sci
, vol.96
, Issue.1
, pp. 1-26
-
-
Wang, W.1
Singh, S.2
Zeng, D.L.3
-
60
-
-
1642433360
-
Effect of excipients on the stability and aerosol performance of nebulized aviscumine
-
Steckel H, Eskandar F, Witthohn K. Effect of excipients on the stability and aerosol performance of nebulized aviscumine. J Aerosol Med 2003;16(4):417-32
-
(2003)
J Aerosol Med
, vol.16
, Issue.4
, pp. 417-432
-
-
Steckel, H.1
Eskandar, F.2
Witthohn, K.3
-
61
-
-
33750932962
-
Rationale for the selection of an aerosol delivery system for gene delivery
-
Lentz YK, Anchordoquy TJ, Lengsfeld CS. Rationale for the selection of an aerosol delivery system for gene delivery. J Aerosol Med 2006;19(3):372-84
-
(2006)
J Aerosol Med
, vol.19
, Issue.3
, pp. 372-384
-
-
Lentz, Y.K.1
Anchordoquy, T.J.2
Lengsfeld, C.S.3
-
62
-
-
70349335728
-
Lipid nanocapsules: Ready-to-use nanovectors for the aerosol delivery of paclitaxel
-
Hureaux J, Lagarce F, Gagnadoux F, et al. Lipid nanocapsules: ready-to-use nanovectors for the aerosol delivery of paclitaxel. Eur J Pharm Biopharm 2009;73(2):239-46
-
(2009)
Eur J Pharm Biopharm
, vol.73
, Issue.2
, pp. 239-246
-
-
Hureaux, J.1
Lagarce, F.2
Gagnadoux, F.3
-
63
-
-
84867890649
-
Impact of lyoprotectants for the stabilization of biodegradable nanoparticles on the performance of air-jet, ultrasonic, and vibrating-mesh nebulizers
-
Beck-Broichsitter M, Kleimann P, Schmehl T, et al. Impact of lyoprotectants for the stabilization of biodegradable nanoparticles on the performance of air-jet, ultrasonic, and vibrating-mesh nebulizers. Eur J Pharm Biopharm 2012;82(2):272-80
-
(2012)
Eur J Pharm Biopharm
, vol.82
, Issue.2
, pp. 272-280
-
-
Beck-Broichsitter, M.1
Kleimann, P.2
Schmehl, T.3
-
64
-
-
0343090205
-
Viscosity effects on nebulisation of aqueous solutions
-
McCallion ON, Patel MJ. Viscosity effects on nebulisation of aqueous solutions. Int J Pharm 1996;130(2):245-9
-
(1996)
Int J Pharm
, vol.130
, Issue.2
, pp. 245-249
-
-
McCallion, O.N.1
Patel, M.J.2
-
65
-
-
84902660472
-
Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy
-
Davies LA, Nunez-Alonso GA, McLachlan G, et al. Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy. Hum Gene Ther Clin Dev 2014;25(2):97-107
-
(2014)
Hum Gene Ther Clin Dev
, vol.25
, Issue.2
, pp. 97-107
-
-
Davies, L.A.1
Nunez-Alonso, G.A.2
McLachlan, G.3
-
66
-
-
0028890246
-
Some factors associated with the ultrasonic nebulization of proteins
-
Niven RW, Ip AY, Mittelman S, et al. Some factors associated with the ultrasonic nebulization of proteins. Pharm Res 1995;12(1):53-9
-
(1995)
Pharm Res
, vol.12
, Issue.1
, pp. 53-59
-
-
Niven, R.W.1
Ip, A.Y.2
Mittelman, S.3
-
67
-
-
0034493781
-
Jet and ultrasonic nebulization of single chain urokinase plasminogen activator (scu-PA
-
Münster AM, Bendstrup E, Jensen JI, Gram J. Jet and ultrasonic nebulization of single chain urokinase plasminogen activator (scu-PA). J Aerosol Med 2000;13(4):325-33
-
(2000)
J Aerosol Med
, vol.13
, Issue.4
, pp. 325-333
-
-
Münster, A.M.1
Bendstrup, E.2
Jensen, J.I.3
Gram, J.4
-
68
-
-
0033061674
-
The conventional ultrasonic nebulizer proved inefficient in nebulizing a suspension
-
Nikander K, Turpeinen M, Wollmer P. The conventional ultrasonic nebulizer proved inefficient in nebulizing a suspension. J Aerosol Med 1999;12(2):47-53
-
(1999)
J Aerosol Med
, vol.12
, Issue.2
, pp. 47-53
-
-
Nikander, K.1
Turpeinen, M.2
Wollmer, P.3
-
69
-
-
69549130597
-
Pharmacokinetics and safety of tobramycin administered by the PARI eFlow rapid nebulizer in cystic fibrosis
-
Hubert D, Leroy S, Nove-Josserand R, et al. Pharmacokinetics and safety of tobramycin administered by the PARI eFlow rapid nebulizer in cystic fibrosis. J Cyst Fibros 2009;8(5):332-7
-
(2009)
J Cyst Fibros
, vol.8
, Issue.5
, pp. 332-337
-
-
Hubert, D.1
Leroy, S.2
Nove-Josserand, R.3
-
70
-
-
84907908041
-
Capturing the efficiency of vibrating mesh nebulizers: Minimizing upper airway deposition
-
Sagalla RB, Smaldone GC. Capturing the efficiency of vibrating mesh nebulizers: minimizing upper airway deposition. J Aerosol Med Pulm Drug Deliv 2014;27(5):341-8
-
(2014)
J Aerosol Med Pulm Drug Deliv
, vol.27
, Issue.5
, pp. 341-348
-
-
Sagalla, R.B.1
Smaldone, G.C.2
-
72
-
-
77950620340
-
Mode of breathing-tidal or slow and deep-through the I-neb adaptive aerosol delivery (AAD) system affects lung deposition of (99m)Tc-DTPA
-
Nikander K, Prince I, Coughlin S, et al. Mode of breathing-tidal or slow and deep-through the I-neb adaptive aerosol delivery (AAD) system affects lung deposition of (99m)Tc-DTPA. J Aerosol Med Pulm Drug Deliv 2010;23(Suppl 1):S37-43
-
(2010)
J Aerosol Med Pulm Drug Deliv
, vol.23
, pp. S37-43
-
-
Nikander, K.1
Prince, I.2
Coughlin, S.3
-
73
-
-
84902381555
-
Thats cool! -Nebulization of thermolabile proteins with a cooled vibrating mesh nebulizer
-
Hertel S, Pohl T, Friess W, Winter G. Thats cool! -Nebulization of thermolabile proteins with a cooled vibrating mesh nebulizer. Eur J Pharm Biopharm 2014;87(2):357-65
-
(2014)
Eur J Pharm Biopharm
, vol.87
, Issue.2
, pp. 357-365
-
-
Hertel, S.1
Pohl, T.2
Friess, W.3
Winter, G.4
-
74
-
-
82955207116
-
Aerosolized gemcitabine in patients with carcinoma of the lung: Feasibility and safety study
-
Lemarie E, Vecellio L, Hureaux J, et al. Aerosolized gemcitabine in patients with carcinoma of the lung: feasibility and safety study. J Aerosol Med Pulm Drug Deliv 2011;24(6):261-70
-
(2011)
J Aerosol Med Pulm Drug Deliv
, vol.24
, Issue.6
, pp. 261-270
-
-
Lemarie, E.1
Vecellio, L.2
Hureaux, J.3
-
75
-
-
21544471534
-
The inhalation of drugs: Advantages and problems
-
Rau JL. The inhalation of drugs: Advantages and problems. Respir Care 2005;50(3):367-82
-
(2005)
Respir Care
, vol.50
, Issue.3
, pp. 367-382
-
-
Rau, J.L.1
-
76
-
-
84889005616
-
On the correlation of output rate and aerodynamic characteristics in vibrating-mesh-based aqueous aerosol delivery
-
Beck-Broichsitter M, Oesterheld N, Knuedeler M-C, et al. On the correlation of output rate and aerodynamic characteristics in vibrating-mesh-based aqueous aerosol delivery. Int J Pharm 2014;461(1-2):34-7
-
(2014)
Int J Pharm
, vol.461
, Issue.1-2
, pp. 34-37
-
-
Beck-Broichsitter, M.1
Oesterheld, N.2
Knuedeler, M.-C.3
-
77
-
-
37549027163
-
Performance of the vibrating membrane aerosol generation device: Aeroneb Micropump Nebulizer
-
Zhang G, David A, Wiedmann TS. Performance of the vibrating membrane aerosol generation device: Aeroneb Micropump Nebulizer. J Aerosol Med 2007;20(4):408-16
-
(2007)
J Aerosol Med
, vol.20
, Issue.4
, pp. 408-416
-
-
Zhang, G.1
David, A.2
Wiedmann, T.S.3
-
78
-
-
34250856236
-
The influence of fluid physicochemical properties on vibratingmesh nebulization
-
Ghazanfari T, Elhissi AM, Ding Z, Taylor KM. The influence of fluid physicochemical properties on vibratingmesh nebulization. Int J Pharm 2007;339(1-2):103-11
-
(2007)
Int J Pharm
, vol.339
, Issue.1-2
, pp. 103-111
-
-
Ghazanfari, T.1
Elhissi, A.M.2
Ding, Z.3
Taylor, K.M.4
-
79
-
-
70349394321
-
Changes in performance of the Pari eFlow rapid and Pari LC Plus during 6 months use by CF patients
-
Rottier BL, van Erp CJP, Sluyter TS, et al. Changes in performance of the Pari eFlow rapid and Pari LC Plus during 6 months use by CF patients. J Aerosol Med Pulm Drug Deliv 2009;22(3):263-9
-
(2009)
J Aerosol Med Pulm Drug Deliv
, vol.22
, Issue.3
, pp. 263-269
-
-
Rottier, B.L.1
Van Erp Cjp2
Sluyter, T.S.3
-
80
-
-
34347233459
-
Does repeated disinfection of the e-Flow rapid nebulizer affect in vitro performance?
-
Bakuridze L, Andrieu V, Dupont C, Dubus J-C. Does repeated disinfection of the e-Flow rapid nebulizer affect in vitro performance? J Cyst Fibros 2007;6(4):309-10
-
(2007)
J Cyst Fibros
, vol.6
, Issue.4
, pp. 309-310
-
-
Bakuridze, L.1
Andrieu, V.2
Dupont, C.3
Dubus, J.-C.4
-
81
-
-
77950621926
-
In vitro characterization of the I-neb adaptive aerosol delivery (AAD) system
-
Hardaker LE, Hatley RH. In vitro characterization of the I-neb adaptive aerosol delivery (AAD) system. J Aerosol Med Pulm Drug Deliv 2010;23(Suppl 1):S11-20
-
(2010)
J Aerosol Med Pulm Drug Deliv
, vol.23
, pp. S11-20
-
-
Hardaker, L.E.1
Hatley, R.H.2
-
82
-
-
78650036519
-
A technical feasibility study of dornase alfa delivery with eFlow vibrating membrane nebulizers: Aerosol characteristics and physicochemical stability
-
Scherer T, Geller DE, Owyang L, et al. A technical feasibility study of dornase alfa delivery with eFlow vibrating membrane nebulizers: Aerosol characteristics and physicochemical stability. J Pharm Sci 2011;100(1):98-109
-
(2011)
J Pharm Sci
, vol.100
, Issue.1
, pp. 98-109
-
-
Scherer, T.1
Geller, D.E.2
Owyang, L.3
-
83
-
-
84882974134
-
Insulin-like growth factor-I aerosol formulations for pulmonary delivery
-
Germershaus O, Schultz I, Lühmann T, et al. Insulin-like growth factor-I aerosol formulations for pulmonary delivery. Eur J Pharm Biopharm 2013;85(1):61-8
-
(2013)
Eur J Pharm Biopharm
, vol.85
, Issue.1
, pp. 61-68
-
-
Germershaus, O.1
Schultz, I.2
Lühmann, T.3
-
84
-
-
33846071525
-
Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: Formulation aspects and stability
-
Kleemann E, Schmehl T, Gessler T, et al. Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: formulation aspects and stability. Pharm Res 2007;24(2):277-87
-
(2007)
Pharm Res
, vol.24
, Issue.2
, pp. 277-287
-
-
Kleemann, E.1
Schmehl, T.2
Gessler, T.3
-
85
-
-
36749091800
-
Studies on aerosol delivery of plasmid DNA using a mesh nebulizer
-
Arulmuthu ER, Williams DJ, Baldascini H, et al. Studies on aerosol delivery of plasmid DNA using a mesh nebulizer. Biotechnol Bioeng 2007;98(5):939-55
-
(2007)
Biotechnol Bioeng
, vol.98
, Issue.5
, pp. 939-955
-
-
Arulmuthu, E.R.1
Williams, D.J.2
Baldascini, H.3
-
86
-
-
84902368367
-
Prediction of protein degradation during vibrating mesh nebulization via a high throughput screening method
-
Hertel S, Pohl T, Friess W, Winter G. Prediction of protein degradation during vibrating mesh nebulization via a high throughput screening method. Eur J Pharm Biopharm 2014;87(2):386-94
-
(2014)
Eur J Pharm Biopharm
, vol.87
, Issue.2
, pp. 386-394
-
-
Hertel, S.1
Pohl, T.2
Friess, W.3
Winter, G.4
-
87
-
-
70649098164
-
Surface active drugs significantly alter the drug output rate from medical nebulizers
-
Arzhavitina A, Steckel H. Surface active drugs significantly alter the drug output rate from medical nebulizers. Int J Pharm 2010;384(1-2):128-36
-
(2010)
Int J Pharm
, vol.384
, Issue.1-2
, pp. 128-136
-
-
Arzhavitina, A.1
Steckel, H.2
-
88
-
-
84885454757
-
Development and characterization of phospholipidstabilized submicron aqueous dispersions of coenzyme Q10 presenting continuous vibrating-mesh nebulization performance
-
Carvalho TC, McCook JP, Narain NR, McConville JT. Development and characterization of phospholipidstabilized submicron aqueous dispersions of coenzyme Q10 presenting continuous vibrating-mesh nebulization performance. J Liposome Res 2013;23(4):276-90
-
(2013)
J Liposome Res
, vol.23
, Issue.4
, pp. 276-290
-
-
Carvalho, T.C.1
McCook, J.P.2
Narain, N.R.3
McConville, J.T.4
-
89
-
-
0033743992
-
Consensus statement: Aerosols and delivery devices
-
Dolovich MB, Macintyre NR, Anderson PJ, et al. Consensus statement: Aerosols and delivery devices. J Aerosol Med 2000;13(3):291-300
-
(2000)
J Aerosol Med
, vol.13
, Issue.3
, pp. 291-300
-
-
Dolovich, M.B.1
Macintyre, N.R.2
Anderson, P.J.3
-
91
-
-
0030984232
-
Comparative measurement of lung deposition of inhaled fine particles in normal subjects and patients with obstructive airway disease
-
Kim CS, Kang TC. Comparative measurement of lung deposition of inhaled fine particles in normal subjects and patients with obstructive airway disease. Am J Respir Crit Care Med 1997;155(3):899-905
-
(1997)
Am J Respir Crit Care Med
, vol.155
, Issue.3
, pp. 899-905
-
-
Kim, C.S.1
Kang, T.C.2
-
92
-
-
0022364523
-
Aerosol deposition in the airway model with excessive mucus secretions
-
Kim CS, Eldridge MA. Aerosol deposition in the airway model with excessive mucus secretions. J Appl Physiol(1985) 1985;59(6):1766-72
-
(1985)
J Appl Physiol 1985
, vol.59
, Issue.6
, pp. 1766-1772
-
-
Kim, C.S.1
Eldridge, M.A.2
-
93
-
-
84876023989
-
Inhaled proteins: Challenges and perspectives
-
Depreter F, Pilcer G, Amighi K. Inhaled proteins: challenges and perspectives. Int J Pharm 2013;447(1-2):251-80
-
(2013)
Int J Pharm
, vol.447
, Issue.1-2
, pp. 251-280
-
-
Depreter, F.1
Pilcer, G.2
Amighi, K.3
-
94
-
-
84869838281
-
Immunogenicity of different stressed IgG monoclonal antibody formulations in immune tolerant transgenic mice
-
Filipe V, Jiskoot W, Basmeleh AH, et al. Immunogenicity of different stressed IgG monoclonal antibody formulations in immune tolerant transgenic mice. mAbs 2012;4(6):740-52
-
(2012)
MAbs
, vol.4
, Issue.6
, pp. 740-752
-
-
Filipe, V.1
Jiskoot, W.2
Basmeleh, A.H.3
-
95
-
-
84878149778
-
Characterization and quantitation of aggregates and particles in interferon-beta products: Potential links between product quality attributes and immunogenicity
-
Barnard JG, Babcock K, Carpenter JF. Characterization and quantitation of aggregates and particles in interferon-beta products: potential links between product quality attributes and immunogenicity. J Pharm Sci 2013;102(3):915-28
-
(2013)
J Pharm Sci
, vol.102
, Issue.3
, pp. 915-928
-
-
Barnard, J.G.1
Babcock, K.2
Carpenter, J.F.3
-
96
-
-
84897869100
-
Immunogenicity of therapeutic proteins: Influence of aggregation
-
Ratanji KD, Derrick JP, Dearman RJ, Kimber I. Immunogenicity of therapeutic proteins: influence of aggregation. J Immunotoxicol 2014;11(2):99-109
-
(2014)
J Immunotoxicol
, vol.11
, Issue.2
, pp. 99-109
-
-
Ratanji, K.D.1
Derrick, J.P.2
Dearman, R.J.3
Kimber, I.4
-
97
-
-
84925507517
-
Small amounts of sub-visible aggregates enhance the immunogenic potential of monoclonal antibody therapeutics
-
Ahmadi M, Bryson CJ, Cloake EA, et al. Small amounts of sub-visible aggregates enhance the immunogenic potential of monoclonal antibody therapeutics. Pharm Res 2014. doi: 10.1007/s11095-014-1541-x
-
(2014)
Pharm Res
-
-
Ahmadi, M.1
Bryson, C.J.2
Cloake, E.A.3
-
98
-
-
77958589565
-
Immunogenicity of therapeutics: A matter of efficacy and safety
-
Nechansky A, Kircheis R. Immunogenicity of therapeutics: A matter of efficacy and safety. Expert Opin Drug Discov 2010;5(11):1067-79
-
(2010)
Expert Opin Drug Discov
, vol.5
, Issue.11
, pp. 1067-1079
-
-
Nechansky, A.1
Kircheis, R.2
-
99
-
-
84926367775
-
Investigation of the immunogenicity of different types of aggregates of a murine monoclonal antibody in mice
-
Freitag AJ, Shomali M, Michalakis S, et al. Investigation of the immunogenicity of different types of aggregates of a murine monoclonal antibody in mice. Pharm Res 2014. doi: 10.1007/s11095-014-1472-6
-
(2014)
Pharm Res
-
-
Freitag, A.J.1
Shomali, M.2
Michalakis, S.3
-
100
-
-
0028332576
-
Protein nebulization I. Stability of lactate dehydrogenase and recombinant granulocyte-colony stimulating factor to air-jet nebulization
-
Niven RW, Ip AY, Mittelman SD, et al. Protein nebulization: I. Stability of lactate dehydrogenase and recombinant granulocyte-colony stimulating factor to air-jet nebulization. Int J Pharm 1994;109(1):17-26
-
(1994)
Int J Pharm
, vol.109
, Issue.1
, pp. 17-26
-
-
Niven, R.W.1
Ip, A.Y.2
Mittelman, S.D.3
-
101
-
-
0035719828
-
The lung as a route for systemic delivery of therapeutic proteins and peptides
-
Agu RU, Ugwoke MI, Armand M, et al. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir Res 2001;2(4):198-209
-
(2001)
Respir Res
, vol.2
, Issue.4
, pp. 198-209
-
-
Agu, R.U.1
Ugwoke, M.I.2
Armand, M.3
-
102
-
-
42149119558
-
Advanced nebulizer designs employing vibrating mesh/aperture plate technologies for aerosol generation
-
Waldrep JC, Dhand R. Advanced nebulizer designs employing vibrating mesh/aperture plate technologies for aerosol generation. Curr Drug Deliv 2008;5(2):114-19
-
(2008)
Curr Drug Deliv
, vol.5
, Issue.2
, pp. 114-119
-
-
Waldrep, J.C.1
Dhand, R.2
-
103
-
-
77952744763
-
Formulation strategy and use of excipients in pulmonary drug delivery
-
Pilcer G, Amighi K. Formulation strategy and use of excipients in pulmonary drug delivery. Int J Pharm 2010;392(1-2):1-19
-
(2010)
Int J Pharm
, vol.392
, Issue.1-2
, pp. 1-19
-
-
Pilcer, G.1
Amighi, K.2
-
104
-
-
76649125889
-
Evaluation of lung tolerance of ethanol, propylene glycol, and sorbitan monooleate as solvents in medical aerosols
-
Montharu J, Le Guellec S, Kittel B, et al. Evaluation of lung tolerance of ethanol, propylene glycol, and sorbitan monooleate as solvents in medical aerosols. J Aerosol Med Pulm Drug Deliv 2010;23(1):41-6
-
(2010)
J Aerosol Med Pulm Drug Deliv
, vol.23
, Issue.1
, pp. 41-46
-
-
Montharu, J.1
Le Guellec, S.2
Kittel, B.3
|