A severe case of adult onset stills disease with myopericarditis, resistant to treatment with tocilizumab but responsive to Anakinra

Ulster Medical Journal

Volumn 84, Issue 2, 2015, Pages 130-132

  Waghmare, Surabhi ^a   Valecka, Bernardas ^b   Cairns, Andrew P ^a  

^a MUSGRAVE PARK HOSPITAL   (United Kingdom)

^b Lisburn BT28 1JP   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BISOPROLOL; C REACTIVE PROTEIN; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; HEMOGLOBIN; METHOTREXATE; METHYLPREDNISOLONE; PREDNISOLONE; RAMIPRIL; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RHEUMATOID FACTOR; STEROID; TOCILIZUMAB; TROPONIN; ANTIRHEUMATIC AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; MONOCLONAL ANTIBODY;

ADULT; ADULT ONSET STILL DISEASE; ARTHRALGIA; CASE REPORT; CLINICAL EXAMINATION; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG MEGADOSE; DYSPNEA; ERYTHROCYTE SEDIMENTATION RATE; FEVER; HEART VENTRICLE TACHYCARDIA; HOSPITAL ADMISSION; HUMAN; LEFT VENTRICULAR SYSTOLIC DYSFUNCTION; LETTER; LOW DRUG DOSE; MALE; MYOCARDITIS; NEUTROPHIL COUNT; NUCLEAR MAGNETIC RESONANCE IMAGING; PERICARDIAL EFFUSION; PERICARDITIS; PLEURA EFFUSION; PLEURISY; SINUS TACHYCARDIA; SORE THROAT; ST SEGMENT ELEVATION; SYMPTOM; SYNOVITIS; THORAX PAIN; THORAX RADIOGRAPHY; TRANSTHORACIC ECHOCARDIOGRAPHY; TREATMENT RESPONSE; ANTAGONISTS AND INHIBITORS; COMPLICATION; RETREATMENT; STILL'S DISEASE, ADULT-ONSET; TREATMENT FAILURE;

ADULT; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIRHEUMATIC AGENTS; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-6; MALE; MYOCARDITIS; PERICARDITIS; PLEURISY; RETREATMENT; STILL'S DISEASE, ADULT-ONSET; TREATMENT FAILURE;

EID: 84929724142     PISSN: 00416193     EISSN: 20464207     Source Type: Journal    
DOI: None     Document Type: Letter

References (5)

1. Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, et al. Preliminary criteria for classification of adult Still’s disease. J. Rheumatol. 1992;19(3):424-30.
2. Vandergheynst F; Gosset J; van de Borne P; Decaux G. Myopericarditis revealing adult-onset Still’s disease Acta Clinica Belgica. 2005: 60(4); 205-8
3. Gonzalez FA, Beirao P, Adriao J, Coelho ML. Adult-onset Still’s disease presenting as myopericarditis. BMJ Case Reports. 2014: Jun 4; bcr-2013-202754.
4. Al-Homood IA. Biologic treatments for adult-onset Still’s disease. Rheumatology (Oxford). 2014;53(1):32-8.
5. De Benedetti F, Brunner HI, Ruperto N, Kenwright A, Wright S, Calvo I, et al. Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis. N Engl J Med. 2012;367(25):2385-95.