Evaluation of biodegradability on polyaspartamide-polylactic acid based nanoparticles by chemical hydrolysis studies

Polymer Degradation and Stability

Volumn 119, Issue , 2015, Pages 56-67

  Craparo, Emanuela Fabiola ^a   Porsio, Barbara ^a   Bondì, Maria Luisa ^b   Giammona, Gaetano ^a   Cavallaro, Gennara ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR   (Italy)

Author keywords

Biodegradability; Graft copolymers; Nanoparticles; Poly(ethylene glycol) (PEG); Poly(lactic acid) (PLA); , Poly (N 2 hydroxyethyl) DL aspartamide (PHEA)

Indexed keywords

BIODEGRADABILITY; BIODEGRADATION; CHEMICAL STABILITY; COPOLYMERS; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); HOMOGENIZATION METHOD; LACTIC ACID; NANOPARTICLES; NANOSYSTEMS; PH; POLYETHYLENE OXIDES;

CHEMICAL HYDROLYSIS; HIGH PRESSURE HOMOGENIZATION; MATRIX COMPOSITION; METHOXYPOLYETHYLENE GLYCOL; POLYLACTIC ACIDS; POLYMERIC NANOPARTICLES; SOLVENT EVAPORATION METHOD; WATER-SOLUBLE PORTIONS;

POLYETHYLENE GLYCOLS;

EID: 84929649905     PISSN: 01413910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.polymdegradstab.2015.05.003     Document Type: Article

References (33)

1. A.A. Date, M.D. Joshi, and V.B. Patravale Parasitic diseases: liposomes and polymeric nanoparticles versus lipid nanoparticles Adv Drug Deliv Rev 59 2007 505 521
2. K.S. Lee, H.C. Chung, S.A. Im, Y.H. Park, C.S. Kim, and S.B. Kim Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer Breast Cancer Res Treat 108 2008 241 250
3. A. Kumari, S.K. Yadav, and S.C. Yadav Biodegradable polymeric nanoparticles based drug delivery systems Colloid Surf B 75 2010 1 18
4. B.D. Ulery, L.S. Nair, and C.T. Laurencin Biomedical applications of biodegradable polymers J Polym Sci Pol Phys 49 2001 832 864
5. E. Marin, M.I. Briceño, and C. Caballero-George Critical evaluation of biodegradable polymers used in nanodrugs Int J Nanomedicine 8 2013 3071 3091
6. D. Hofmann, M. Entrialgo-Castano, K. Kratz, and A. Lendlein Knowledge-based approach towards hydrolytic degradation of polymer-based biomaterials Adv Mater 21 2009 3237 3245
7. K.M. Nampoothiri, N.R. Nair, and R.P. John An overview of the recent developments in polylactide (PLA) research Bioresour Technol 101 2010 8493 8501
8. M.C. Araque-Monrós, A. Vidaurre, L. Gil-Santos, S.G. Bernabé, M. Monleón-Pradas, and J. Más-Estellés Study of the degradation of a new PLA braided biomaterial in buffer phosphate saline, basic and acid media, intended for the regeneration of tendons and ligaments Polym Degrad Stab 98 2013 1563 1570
9. B. Saulnier, J. Coudane, H. Garreau, and M. Vert Hydroxyl-bearing poly(α-hydroxy acid)-type aliphatic degradable polyesters prepared by ring opening (co)polymerization of dilactones based on glycolic, gluconic and l-lactic acids Polymer 47 2006 1921 1929
10. B. He, Y.F. Poon, J. Feng, and M.B. Chan-Park Synthesis and characterization of functionalized biodegradable poly(DL-lactide-co-RS-β-malic acid) J Biomed Mater Res 87A 2008 254 263
11. L.L. Ma, P. Jie, and S. Venkatraman Block copolymer 'stealth' nanoparticles for chemotherapy: 1. Interactions with blood cells in vitro Adv Funct Mater 18 2008 716 725
12. Y. Sheng, L. Changshenf, Y. Yuan, Y. Sheng, T. Xinyi, and Y. Fan Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan Biomaterials 30 2009 2340 2348
13. G. Giammona, B. Carlisi, and S. Palazzo α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide with derivatives of carboxylic acids J Polym Sci Polym Chem Ed 25 1987 2813 2818
14. R. Mendichi, A. Giacometti Schieroni, G. Cavallaro, M. Licciardi, and G. Giammona Molecular characterization of α,β-poly(N-2-hydroxyethyl)-DL-aspartamide derivatives as potential self-assembling copolymers forming polymeric micelles Polymer 44 2003 4871 4879
15. G. Cavallaro, L. Maniscalco, P. Caliceti, S. Salmaso, A. Semenzato, and G. Giammona Glycosilated macromolecular conjugates of antiviral drugs with a polyaspartamide J Drug Target 12 2004 593 605
16. E.F. Craparo, G. Cavallaro, M.L. Bondì, D. Mandracchia, and G. Giammona Pegylated nanoparticles based on a polyaspartamide. Preparation, physico-chemical characterization and intracellular uptake Biomacromolecules 7 2006 3083 3092
17. E.F. Craparo, M.C. Ognibene, M.P. Casaletto, G. Pitarresi, G. Teresi, and G. Giammona Biocompatible polymeric micelles with polysorbate 80 for use in brain targeting Nanotechnology 19 2008 485603
18. C. Civiale, M. Licciardi, G. Cavallaro, G. Giammona, and M.G. Mazzone Polyhydroxyethylaspartamide-based micelles for ocular drug delivery Int J Pharm 378 2009 177 186
19. E.F. Craparo, G. Teresi, M.L. Bondi', M. Licciardi, and G. Cavallaro Phospholipid-polyaspartamide micelles for pulmonary delivery of corticosteroids Int J Pharm 406 2011 135 144
20. M. Licciardi, M. Di Stefano, E.F. Craparo, G. Amato, G. Fontana, and G. Cavallaro PHEA-graft-polybutylmethacrylate copolymer microparticles for delivery of hydrophobic drugs Int J Pharm 433 2012 16 24
21. E.F. Craparo, C. Sardo, R. Serio, M.G. Zizzo, M.L. Bondì, and G. Giammona Galactosylated polymeric carriers for liver targeting of sorafenib Int J Pharm 466 2014 172 180
22. E.F. Craparo, B. Porsio, N. Mauro, G. Giammona, and G. Cavallaro Polyaspartamide-polylactide graft copolymers with tunable properties for the realization of fluorescent nanoparticles for imaging Macromol Rapid Commun 2015 10.1002/marc.201500154 [in press]
23. E.F. Craparo, G. Teresi, M.C. Ognibene, M.P. Casaletto, M.L. Bondì, and G. Cavallaro Nanoparticles based on novel amphiphilic polyaspartamide copolymers J Nanopart Res 12 2010 2629 2644
24. E.F. Craparo, G. Teresi, M. Licciardi, M.L. Bondì, and G. Cavallaro Novel composed galactosylated nanodevices containing a ribavirin prodrug as hepatic cell-targeted carriers for HCV treatment J Biomed Nanotechnol 9 2013 1107 1122
25. E.F. Craparo, D. Triolo, G. Pitarresi, G. Giammona, and G. Cavallaro Galactosylated micelles for a ribavirin prodrug targeting to hepatocytes Biomacromolecules 14 2013 1838 1849
26. T. Etrych, M. Jelinkova, B. Rihova, and K. Ulbrich New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage, synthesis and preliminary in vitro and in vivo biological properties J Control Release 73 2001 89 102
27. W.J. Lin, and M.H. Chen Synthesis of multifunctional chitosan with galactose pendant as targeting ligand for glycoprotein receptor Carbohydr Polym 67 2007 474 480
28. A.P. Gupta, and V. Kumar New emerging trends in synthetic biodegradable polymers - polylactide: a critique Eur Polym J 43 2007 4053 4074
29. I. Grizzi, H. Garreau, S. Li, and M. Vert Hydrolytic degradation of devices based on poly(DL-lactic acid) size-dependence Biomaterials 16 1996 305 311
30. M.L.T. Zweers, G.H.M. Engbers, D.W. Grijpma, and J. Feijen In vitro degradation of nanoparticles prepared from polymers based on DL-lactide, glycolide and poly(ethylene oxide) J Control Release 100 2004 347 356
31. H. Zhang, W. Cui, J. Bei, and S. Wang Preparation of poly(lactide-co-glycolide-co-caprolactone) nanoparticles and their degradation behaviour in aqueous solution Polym Degrad Stab 91 2006 1929 1936
32. X.Y. Xiong, K.C. Tam, and L.H. Gan Hydrolytic degradation of Pluronic F127/Poly(lactic acid) block copolymer nanoparticles Macromolecules 37 2004 3425 3430
33. G. Schliecker, C. Schmidt, S. Fuchs, and T. Kissel Characterization of a homologous series of d,l-lactic acid oligomers; a mechanistic study on the degradation kinetics in vitro Biomaterials 24 2003 3835 3844