Magnetization transfer from inhomogeneously broadened lines (ihMT): Experimental optimization of saturation parameters for human brain imaging at 1.5 Tesla

Magnetic Resonance in Medicine

Volumn 73, Issue 6, 2015, Pages 2111-2121

  Girard, Olivier M ^a   Prevost, Valentin H ^a   Varma, Gopal ^b   Cozzone, Patrick J ^a   Alsop, David C ^b   Duhamel, Guillaume ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

ihMT; inhomogeneously broadened lines; magnetization transfer; myelin; specificity; white matter

Indexed keywords

BRAIN MAPPING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

IHMT; INHOMOGENEOUSLY BROADENED LINES; MAGNETIZATION TRANSFER; MYELIN; SPECIFICITY; WHITE MATTER;

SATURATION MAGNETIZATION;

ADULT; ARTICLE; CAPSULA INTERNA; CINGULATE GYRUS; CLINICAL TRIAL; CONTRAST; CONTROLLED STUDY; CORPUS CALLOSUM; DIGITAL IMAGING AND COMMUNICATIONS IN MEDICINE; GRAY MATTER; HEMISPHERE; HUMAN; HUMAN TISSUE; IMAGE QUALITY; INHOMOGENEOUS MAGNETIZATION TRANSFER; MYELINATION; NEUROIMAGING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PROCESS OPTIMIZATION; PUTAMEN; QUANTITATIVE ANALYSIS; RADIOFREQUENCY; RADIOSENSITIVITY; SIGNAL PROCESSING; SPINAL CORD; THALAMUS; TIME; WHITE MATTER; YOUNG ADULT; ANATOMY AND HISTOLOGY; BRAIN MAPPING; IMAGE ENHANCEMENT; IMAGE PROCESSING; PROCEDURES; SENSITIVITY AND SPECIFICITY;

BRAIN MAPPING; HEALTHY VOLUNTEERS; HUMANS; IMAGE ENHANCEMENT; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; SENSITIVITY AND SPECIFICITY; WHITE MATTER;

EID: 84929620367     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.25330     Document Type: Article

References (36)

1. Wolff SD, Balaban RS,. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn Reson Med 1989; 10: 135-144.
2. Henkelman RM, Stanisz GJ, Graham SJ,. Magnetization transfer in MRI: a review. NMR Biomed 2001; 14: 57-64.
3. Eng J, Ceckler TL, Balaban RS,. Quantitative 1H magnetization transfer imaging in vivo. Magn Reson Med 1991; 17: 304-314.
4. Henkelman RM, Huang X, Xiang Q-S, Stanisz GJ, Swanson SD, Bronskill MJ,. Quantitative interpretation of magnetization transfer. Magn Reson Med 1993; 29: 759-766.
5. Sled JG, Pike GB,. Quantitative imaging of magnetization transfer exchange and relaxation properties in vivo using MRI. Magn Reson Med 2001; 46: 923-931.
6. Sinclair CDJ, Samson RS, Thomas DL, Weiskopf N, Lutti A, Thornton JS, Golay X,. Quantitative magnetization transfer in in vivo healthy human skeletal muscle at 3 T. Magn Reson Med 2010; 64: 1739-1748.
7. Yarnykh VL, Yuan C,. Cross-relaxation imaging reveals detailed anatomy of white matter fiber tracts in the human brain. Neuroimage 2004; 23: 409-424.
8. Gloor M, Scheffler K, Bieri O,. Quantitative magnetization transfer imaging using balanced SSFP. Magn Reson Med 2008; 60: 691-700.
9. Schmierer K, Tozer DJ, Scaravilli F, Altmann DR, Barker GJ, Tofts PS, Miller DH,. Quantitative magnetization transfer imaging in postmortem multiple sclerosis brain. J Magn Reson Imaging 2007; 26: 41-51.
10. Underhill HR, Rostomily RC, Mikheev AM, Yuan C, Yarnykh VL,. Fast bound pool fraction imaging of the in vivo rat brain: association with myelin content and validation in the C6 glioma model. Neuroimage 2011; 54: 2052-2065.
11. Samsonov A, Alexander AL, Mossahebi P, Wu Y-C, Duncan ID, Field AS,. Quantitative MR imaging of two-pool magnetization transfer model parameters in myelin mutant shaking pup. Neuroimage 2012; 62: 1390-1398.
12. Morrison C, Stanisz G, Henkelman RM,. Modeling magnetization transfer for biological-like systems using a semi-solid pool with a super-Lorentzian lineshape and dipolar reservoir. J Magn Reson B 1995; 108: 103-113.
13. Wennerström H,. Proton nuclear magnetic resonance lineshapes in lamellar liquid crystals. Chem Phys Lett 1973; 18: 41-44.
14. Bloom M, Burnell EE, Roeder SBW, Valic MI,. Nuclear magnetic resonance line shapes in lyotropic liquid crystals and related systems. J Chem Phys 1977; 66: 3012.
15. Seiter CHA, Chan SI,. Molecular motion in lipid bilayers. Nuclear magnetic resonance line width study. J Am Chem Soc 1973; 95: 7541-7553.
16. Kumashiro KK, Schmidt-Rohr K, Murphy OJ, Ouellette KL, Cramer WA, Thompson LK,. A novel tool for probing membrane protein structure: solid-state NMR with proton spin diffusion and X-nucleus detection. J Am Chem Soc 1998; 120: 5043-5051.
17. Huster D, Yao X, Hong M,. Membrane protein topology probed by 1H spin diffusion from lipids using solid-state NMR spectroscopy. J Am Chem Soc 2002; 124: 874-883.
18. Morrison C, Mark Henkelman R,. A model for magnetization transfer in tissues. Magn Reson Med 1995; 33: 475-482.
19. Alsop DC, de Bazelaire C, Duhamel G,. In-vivo imaging of an inhomogeneous component of magnetization transfer in human white matter. In Proceedings of the 11th Annual Meeting of ISMRM, Kyoto, Japan, 2004. Abstract 2324.
20. Alsop DC, de Bazelaire C, Garcia DM, Duhamel G,. Inhomogenous magnetization transfer imaging: a potentially specific marker for myelin. In Proceedings of the 13th Annual Meeting of ISMRM, Miami, Florida, USA, 2005. Abstract 2224.
21. Varma G, Duhamel G, de Bazelaire C, Alsop DC,. Magnetization transfer from inhomogeneously broadened lines: a potential marker for myelin. Magn Reson Med 2014. doi: 10.1002/mrm.25174.
22. Alsop DC, Dandamudi R, Bakshi R,. Inhomogeneous magnetization transfer imaging of myelin concentration in multiple sclerosis. In Proceedings of the Joint Annual Meeting of ISMRM-ESMRMB, Berlin, Germany, 2007. Abstract 2188.
23. Varma G, Schlaug G, Alsop DC,. 3D Acquisition of the inhomogeneous magnetization transfer effect for greater white matter contrast. In Proceedings of the 21st Annual Meeting of ISMRM, Salt Lake City, Utah, USA, 2013. Abstract 4224.
24. Rangwala N, Varma G, Hackney D, Alsop DC,. Quantification of myelin in the cervical spinal cord using inhomogeneous magnetization transfer imaging. In Proceedings of the 21st Annual Meeting of ISMRM, Salt Lake City, Utah, USA, 2013. Abstract 350.
25. Girard OM, Callot V, Vignaud A, Varma G, Cozzone PJ, Alsop DC, Duhamel G,. Specific inhomogeneous MT contrast in white matter. Application to spinal cord imaging. In Proceedings of the 21st Annual Meeting of ISMRM, Salt Lake City, Utah, USA, 2013. Abstract 2506.
26. Duhamel G, Girard OM, Varma G, Cozzone PJ, Callot V, Alsop DC,. Specific inhomogeneous MT contrast in mouse brain white matter. In Proceedings of the 21st Annual Meeting of ISMRM, Salt Lake City, Utah, USA, 2013. Abstract 2535.
27. Scheidegger R, Vinogradov E, Alsop DC,. Amide proton transfer imaging with improved robustness to magnetic field inhomogeneity and magnetization transfer asymmetry using saturation with frequency alternating RF irradiation. Magn Reson Med 2011; 66: 1275-1285.
28. International Electrotechnical Commission. Medical electrical equipment. Part 2-33: Particular requirements for the basic safety and essential performance of magnetic resonance equipment for medical diagnosis. IEC 60601-2-33; 2010.
29. Vavasour IM, Whittall KP, MacKay AL, Li DK, Vorobeychik G, Paty DW,. A comparison between magnetization transfer ratios and myelin water percentages in normals and multiple sclerosis patients. Magn Reson Med 1998; 40: 763-768.
30. Sled JG, Levesque I, Santos AC, Francis SJ, Narayanan S, Brass SD, Arnold DL, Pike GB,. Regional variations in normal brain shown by quantitative magnetization transfer imaging. Magn Reson Med 2004; 51: 299-303.
31. Girard OM, Prevost V, Varma G, Alsop DC, Duhamel G,. Magnetization transfer from inhomogeneously broadened lines (ihMT): field strength dependency. In Proceedings of the 22nd Annual Meeting of ISMRM, Milan, Italy, 2014. Abstract 4236.
32. Smith SA, Bulte JWM, van Zijl PCM,. Direct saturation MRI: theory and application to imaging brain iron. Magn Reson Med 2009; 62: 384-393.
33. Varma G, Kourtelidis F, Alsop DC,. Quantitative evaluation of the exchange time and T2 associated with an inhomogeneous component using inhomogeneous magnetization transfer imaging. In Proceedings of the 21st Annual Meeting of ISMRM, Salt Lake City, Utah, USA, 2013. Abstract 2536.
34. Stanisz GJ, Odrobina EE, Pun J, Escaravage M, Graham SJ, Bronskill MJ, Henkelman RM,. T1, T2 relaxation and magnetization transfer in tissue at 3T. Magn Reson Med 2005; 54: 507-512.
35. Zhou J, van Zijl PCM,. Chemical exchange saturation transfer imaging and spectroscopy. Prog Nucl Magn Reson Spectrosc 2006; 48: 109-136.
36. Laule C, Vavasour IM, Kolind SH, Li DK, Traboulsee TL, Moore GR, MacKay AL,. Magnetic resonance imaging of myelin. Neurotherapeutics 2007; 4: 460-484.