Homer1a disruption increases vulnerability to predictable subtle stress normally sub-threshold for behavioral changes

Brain Research

Volumn 1605, Issue 1, 2015, Pages 70-75

  Shui, Yuan ^a,b   Wang, Li ^a,b   Luo, Xianwen ^a,c   Uchiumi, Osamu ^a   Yamamoto, Ryo ^a   Sugai, Tokio ^a   Kato, Nobuo ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Chronic restraint stress; Homer1a; Neuronal excitability; Synaptic efficiency

Indexed keywords

PROTEIN HOMER 1A; CARRIER PROTEIN; PROTEIN HOMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR CHANGE; CINGULATE GYRUS; CONTROLLED STUDY; DEPRESSION; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; FORCED SWIM TEST; HIPPOCAMPAL CA1 REGION; IMMOBILIZATION STRESS; LOCOMOTION; MALE; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SPIKE WAVE; STRESS; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; EXERCISE; KNOCKOUT MOUSE; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

MUS;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; CA1 REGION, HIPPOCAMPAL; CARRIER PROTEINS; DEPRESSION; EXCITATORY POSTSYNAPTIC POTENTIALS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PYRAMIDAL CELLS; RESTRAINT, PHYSICAL; STRESS, PHYSIOLOGICAL;

EID: 84929603942     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.02.008     Document Type: Article

References (31)

1. Ary, A. W., Aguilar, V. R., Szumlinski, K. K., Kippin, T. E., 2007. Prenatal stress alters limbo-corticostriatal Homer protein expression. Synapse 61, 938-941.
2. Bledsoe, J. C., Semrud-Clikeman, M., Pliszka, S. R., 2013. Anterior cingulate cortex and symptom severity in attention-deficit/hyperactivity disorder. J. Abnorm. Psychol. 122, 558-565.
3. Brakeman, P. R., Lanahan, A. A., O'Brien, R., Roche, K., Barnes, C. A., Huganir, R. L., Worley, P. F., 1997. Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386, 284-288.
4. Bush, G., Valera, E. M., Seidman, L. J., 2005. Functional neuroimaging of attentiondeficit/hyperactivity disorder: a review and suggested future directions. Biol. Psychiatry 57, 1273-1284.
5. D'Aquila, P. S., Peana, A. T., Carboni, V., Serra, G., 2000. Exploratory behavior and grooming after repeated restraint and chronic mild stress: effect of desipramine. Eur. J. Pharmacol. 399, 43-47.
6. Grippo, A. J., Beltz, T. G., Johnson, A. K., 2003. Behavioral and cardiovascular changes in the chronic mild stress model of depression. Physiol. Behav. 78, 703-710.
7. Gronli, J., Murison, R., Fiske, E., Bjorvatn, B., Sorensen, E., Portas, C. M., Ursin, R., 2005. Effects of chronic mild stress on sexual behavior, locomotor activity and consumption of sucrose and saccharine solutions. Physiol. Behav. 84, 571-577.
8. Harris, R. B., Zhou, J., Youngblood, B. D., Smagin, G. N., Ryan, D. H., 1997. Failure to change exploration or saccharin preference in rats exposed to chronic mild stress. Physiol. Behav. 63, 91-100.
9. Holmes, P. V., 2003. Rodent models of depression: reexamining validity without anthropomorphic inference. Crit. Rev. Neurobiol. 15, 143-174.
10. Inoue, N., Nakao, H., Migishima, R., Hino, T., Matsui, M., Hayashi, F., Nakao, K., Manabe, T., Aiba, A., Inokuchi, K., 2009. Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation. Mol. Brain 5, 2-7.
11. Ito, H., Nagano, M., Suzuki, H., Murakoshi, T., 2010. Chronic stress enhances synaptic plasticity due to disinhibition in the anterior cingulate cortex and induces hyper-locomotion in mice. Neuropharmacology 58, 746-757.
12. Kato, A., Ozawa, F., Saitoh, Y., Hirai, K., Inokuchi, K., 1997. Vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesis. FEBS Lett. 412, 183-189.
13. Klugmann, M., Symes, C. W., Leichtlein, C. B., Klaussner, B. K., Dunning, J., Fong, D., Young, D., During, M. J., 2005. AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats. Mol. Cell. Neurosci. 28, 347-360.
14. Lominac, K. D., Oleson, E. B., Pava, M., Klugmann, M., Schwarz, M. K., Seeburg, P. H., During, M. J., Worley, P. F., Kalivas, P. W., Szumlinski, K. K., 2005. Distinct roles for different Homer1 isoforms in behaviors and associated prefrontal cortex function. J. Neurosci. 25, 11586-11594.
15. Maguire, J., Salpekar, J. A., 2013. Stress, seizures, and hypothalamic-pituitary-adrenal axis targets for the treatment of epilepsy. Epilepsy Behav. 26, 352-362.
16. Maret, S., Dorsaz, S., Gurcel, L., Pradervand, S., Petit, B., Pfister, C., Hagenbuchle, O., O'Hara, B. F., Franken, P., Tafti, M., 2007. Homer1a is a core brain molecular correlate of sleep loss. Proc. Natl. Acad. Sci. USA 104, 20090-20095.
17. McEwen, B. S., Stellar, E., 1993. Stress and the individual: mechanisms leading to disease. Arch. Intern. Med. 153, 2093-2101.
18. Mineur, Y. S., Belzung, C., Crusio, W. E., 2006. Effects of unpredictable chronic mild stress on anxiety and depressionlike behavior in mice. Behav. Brain Res. 175, 43-50.
19. Nestler, E. J., Hyman, S. E., 2010. Animal models of neuropsychiatric disorders. Nat. Neurosci. 13, 1161-1169.
20. O'Toole, K. K., Hooper, A., Wakefield, S., Maguire, J., 2014. Seizureinduced disinhibition of the HPA axis increases seizure susceptibility. Epilepsy Res. 108, 29-43.
21. Porsolt, R. D., Bertin, A., Jalfre, M., 1978. "Behavioural despair" in rats and mice: strain differences and the effects of imipramine. Eur. J. Pharmacol. 51, 291-294.
22. Potschka, H., Krupp, E., Ebert, U., Gümbel, C., Leichtlein, C., Lorch, B., Pickert, A., Kramps, S., Young, K., Grüne, U., Keller, A., Welschof, M., Vogt, G., Xiao, B., Worley., P. F., Löscher, W., Hiemisch, H., 2002. Kindling-induced overexpression of Homer 1A and its functional implications for epileptogenesis. Eur. J. Neurosci. 16, 2157-2165.
23. Rietschel, M., Mattheisen, M., Frank, J., Treutlein, J., Degenhardt, F., Breuer, R., Steffens, M., Mier, D., Esslinger, C., Walter, H., Kirsch, P., Erk, S., Schnell, K., Herms, S., Wichmann, H. E., Schreiber, S., Jockel, K. H., Strohmaier, J., Roeske, D., Haenisch, B., Gross, M., Hoefels, S., Lucae, S., Binder, E. B., Wienker, T. F., Schulze, T. G., Schmal, C., Zimmer, A., Juraeva, S., Brors, B., Bettecken, T., Meyer-Lindenberg, A., Muller-Myhsok, B., Maier, W., Nothen, M. M., Cichon, S., 2010. Genome-wide association, replication, and neuroimaging study implications HOMER1 in the etiology of major depression. Biol. Psychiatry 68, 578-585.
24. Sakagami, Y., Yamamoto, K., Sugiura, S., Inokuchi, K., Hayashi, T., Kato, N., 2005. Essential roles of Homer-1a in homeostatic regulation of pyramidal cell excitability: a possible link to clinical benefits of electroconvulsive shock. Eur. J. Neurosci. 21, 3229-3239.
25. Seidman, L. J., Valera, E. M., Makris, N., Monuteaux, M. C., Boriel, D. L., Kelkar, K., Kennedy, D. N., Caviness, V. S., Bush, G., Aleardi, M., Faraone, S. V., Biederman, J., 2006. Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imaging. Biol. Psychiatry 60, 1071-1080.
26. Sun, P., Wang, F., Wang, L., Zhang, Yu., Yamamoto, R., Sugai, T., Zhang, Q., Wang, Z., Kato, N., 2011. Increase in cortical pyramidal cell excitability accompanies depression-like behavior in mice: a transcranial magnetic stimulation study. J. Neurosci. 31, 16464-16472.
27. Szumlinski, K. K., Kalivas, P. W., Worley, P. F., 2006. Homer proteins: implications for neuropsychiatric disorders. Curr. Opin. Neurobiol. 16, 251-257.
28. Tappe, A., Kuner, R., 2006. Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family. Proc. Natl. Acad. Sci. USA 103, 774-779.
29. Veenema, A. H., Meijer, O. C., De Kloet, E. R., Koolhaas, J. M., 2003. Genetic selection for coping style predicts stressor susceptibility. J. Neuroendocrinol. 15, 256-267.
30. Willner, P., 1997. Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology (Berl) 134, 319-329.
31. Willner, P., 2005. Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. Neuropsychobiology 52, 90-110.