Extracellular vesicles secreted by bone marrow- and adipose tissue-derived mesenchymal stromal cells fail to suppress lymphocyte proliferation

Stem Cells and Development

Volumn 24, Issue 11, 2015, Pages 1374-1376

  Gouveia De Andrade, Ana Valéria ^a,b   Bertolino, Giuliana ^a,b   Riewaldt, Julia ^a   Bieback, Karen ^c   Karbanová, Jana ^d   Odendahl, Marcus ^a   Bornhäuser, Martin ^b,e   Schmitz, Marc ^a,b   Corbeil, Denis ^b,d   Tonn, Torsten ^a,b  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE DERIVED MESENCHYMAL STROMAL CELL; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL FREE SYSTEM; CELL INTERACTION; CELL ISOLATION; CELL PROLIFERATION ASSAY; CELL STIMULATION; EXOSOME; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE PROLIFERATION ASSAY; MESENCHYMAL STROMA CELL; PRIORITY JOURNAL; ADIPOSE TISSUE; BONE MARROW CELL; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; IMMUNOLOGY; LYMPHOCYTE; PHYSIOLOGY;

IMMUNOSUPPRESSIVE AGENT;

ADIPOSE TISSUE; BONE MARROW CELLS; CELL PROLIFERATION; CELLS, CULTURED; EXTRACELLULAR VESICLES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTES; MESENCHYMAL STROMAL CELLS;

EID: 84929574438     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2014.0563     Document Type: Article

References (4)

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2. Conforti A, M Scarsella, N Starc, E Giorda, S Biagini, A Proia, R Carsetti, F Locatelli and ME Bernardo. (2014). Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro. Stem Cells Dev 23: 2591-2599.
3. de Andrade AV, J Riewaldt, R Wehner, M Schmitz, M Odendahl, M Bornhäuser and T Tonn. (2014). Gamma irradiation preserves immunosuppressive potential and inhibits clonogenic capacity of human bone marrow-derived mesenchymal stromal cells. J Cell Mol Med 18:1184-1193.
4. Kern S, H Eichler, J Stoeve, H Klüter and K Bieback. (2006). Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells Dev 24:1294-1301.