Disruption of melatonin circadian rhythm production is related to multiple sclerosis severity: A preliminary study

Journal of the Neurological Sciences

Volumn 353, Issue 1-2, 2015, Pages 166-168

  Damasceno, Alfredo ^a   Moraes, Adriel Santos ^a   Farias, Alessandro ^a   Damasceno, Benito Pereira ^a   Dos Santos, Leonilda Maria Barbosa ^a   Cendes, Fernando ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

6 Sulfatoxymelatonin; Biomarker; Melatonin; Multiple sclerosis

Indexed keywords

6 HYDROXYMELATONIN O SULFATE; MELATONIN; 6-SULFATOXYMELATONIN; CREATININE; CYTOKINE;

ADULT; ARTICLE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; DISABILITY; DISEASE ASSOCIATION; DISEASE SEVERITY; EXPANDED DISABILITY STATUS SCALE; FATIGUE; FEMALE; HORMONE INHIBITION; HORMONE URINE LEVEL; HUMAN; MALE; MULTIPLE SCLEROSIS; NEUROLOGIC EXAMINATION; PRIORITY JOURNAL; RELAPSE; ANALOGS AND DERIVATIVES; BLOOD; CHRONOBIOLOGY DISORDERS; COMPLICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; NONPARAMETRIC TEST; YOUNG ADULT;

ADULT; CHRONOBIOLOGY DISORDERS; CREATININE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MELATONIN; MULTIPLE SCLEROSIS; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 84929515546     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2015.03.040     Document Type: Article

References (10)

1. J.R. Calvo, C. González-Yanes, and M.D. Maldonado The role of melatonin in the cells of the innate immunity: a review J Pineal Res 55 2013 103 120 10.1111/jpi.12075
2. A. Carrillo-Vico, P.J. Lardone, N. Alvarez-Sánchez, A. Rodríguez-Rodríguez, and J.M. Guerrero Melatonin: buffering the immune system Int J Mol Sci 14 2013 8638 8683 10.3390/ijms14048638
3. L. Melamud, D. Golan, R. Luboshitzky, I. Lavi, and A. Miller Melatonin dysregulation, sleep disturbances and fatigue in multiple sclerosis J Neurol Sci 314 2012 37 40 10.1016/j.jns.2011.11.003
4. Z. Akpinar, S. Tokgöz, H. Gökbel, N. Okudan, F. Uʇuz, and G. Yilmaz The association of nocturnal serum melatonin levels with major depression in patients with acute multiple sclerosis Psychiatry Res 161 2008 253 257 10.1016/j.psychres.2007.11.022
5. R. Sandyk Multiple sclerosis: the role of puberty and the pineal gland in its pathogenesis Int J Neurosci 68 1993 209 225
6. L.A. Carvalho, C. Gorenstein, R.A. Moreno, and R.P. Markus Melatonin levels in drug-free patients with major depression from the southern hemisphere Psychoneuroendocrinology 31 2006 761 768
7. S. Benloucif, H.J. Burgess, E.B. Klerman, A.J. Lewy, B. Middleton, and P.J. Murphy Measuring melatonin in humans J Clin Sleep Med 4 2008 66 69
8. C. Bahamonde, C. Conde, E. Agüera, R. Lillo, E. Luque, and F. Gascón Elevated melatonin levels in natalizumab-treated female patients with relapsing-remitting multiple sclerosis: relationship to oxidative stress Eur J Pharmacol 730 2014 26 30 10.1016/j.ejphar.2014.02.020
9. T. Gholipour, T. Ghazizadeh, S. Babapour, B. Mansouri, M. Ghafarpour, and B. Siroos Decreased urinary level of melatonin as a marker of disease severity in patients with multiple sclerosis Iran J Allergy Asthma Immunol 14 2015 91 97
10. A. López-González, N. Álvarez-Sánchez, P.J. Lardone, I. Cruz-Chamorro, A. Martínez-López, and J.M. Guerrero Melatonin treatment improves primary progressive multiple sclerosis: a case report J Pineal Res 58 2015 173 177 10.1111/jpi.12203