Human pluripotent stem cell tools for cardiac optogenetics

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Volumn , Issue , 2014, Pages 6171-6174

  Zhuge, Yan ^b   Patlolla, Bhagat ^b   Ramakrishnan, Charu ^b   Beygui, Ramin E ^b   Zarins, Christopher K ^b   Deisseroth, Karl ^b   Kuhl, Ellen ^b   Abilez, Oscar J ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PATIENT TREATMENT;

DIRECTED DIFFERENTIATIONS; ELECTRICAL STIMULATIONS; HUMAN EMBRYONIC STEM CELLS (HESC); LENTIVIRAL VECTOR; LIGHT STIMULATION; OPTICAL CONTROL; OPTICAL STIMULATION; PLURIPOTENT STEM CELLS;

STEM CELLS;

CHANNELRHODOPSIN 2, HUMAN; RHODOPSIN;

ARRHYTHMIAS, CARDIAC; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; EMBRYONIC STEM CELL; GENE VECTOR; GENETICS; HEART MUSCLE CELL; HUMAN; LENTIVIRINAE; LIGHT; METABOLISM; OPTOGENETICS; PATHOLOGY; PLURIPOTENT STEM CELL; RADIATION RESPONSE; TRANSPLANTATION; VIDEO MICROSCOPY;

ARRHYTHMIAS, CARDIAC; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; GENETIC VECTORS; HUMANS; LENTIVIRUS; LIGHT; MICROSCOPY, VIDEO; MYOCYTES, CARDIAC; OPTOGENETICS; PLURIPOTENT STEM CELLS; RHODOPSIN;

EID: 84929484223     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/EMBC.2014.6945038     Document Type: Conference Paper

References (23)

1. J. Zhang, G. F. Wilson, A. G. Soerens, C. H. Koonce, J. Yu, S. P. Palecek, J. A. Thomson, and T. J. Kamp, "Functional cardiomyocytes derived from human induced pluripotent stem cells," Circulation Research, Vol. 104, (no. 4), pp. e30-41, Feb 2009.
2. N. Sun, M. Yazawa, J. Liu, L. Han, V. Sanchez-Freire, O. J. Abilez, E. G. Navarrete, S. Hu, L. Wang, A. Lee, A. Pavlovic, S. Lin, R. Chen, R. J. Hajjar, M. P. Snyder, R. E. Dolmetsch, M. J. Butte, E. A. Ashley, M. T. Longaker, R. C. Robbins, and J. C. Wu, "Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy," Science translational medicine, Vol. 4, (no. 130), pp. 130ra47, Apr 2012.
3. F. Lan, A. S. Lee, P. Liang, V. Sanchez-Freire, P. K. Nguyen, L. Wang, L. Han, M. Yen, Y. Wang, N. Sun, O. J. Abilez, S. Hu, A. D. Ebert, E. G. Navarrete, C. S. Simmons, M. Wheeler, B. Pruitt, R. Lewis, Y. Yamaguchi, E. A. Ashley, D. M. Bers, R. C. Robbins, M. T. Longaker, and J. C. Wu, "Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells," Cell stem cell, Vol. 12, (no. 1), pp. 101-13, Jan 2013.
4. J. Yu, M. A. Vodyanik, K. Smuga-Otto, J. Antosiewicz-Bourget, J. L. Frane, S. Tian, J. Nie, G. A. Jonsdottir, V. Ruotti, R. Stewart, Slukvin, II, and J. A. Thomson, "Induced pluripotent stem cell lines derived from human somatic cells," Science, Vol. 318, (no. 5858), pp. 1917-20, 2007.
5. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka, "Induction of pluripotent stem cells from adult human fibroblasts by defined factors," Cell, Vol. 131, pp. 861-872, 2007.
6. W. Roell, T. Lewalter, P. Sasse, Y. N. Tallini, B.-R. Choi, M. Breitbach, R. Doran, U. M. Becher, S.-M. Hwang, T. Bostani, J. von Maltzahn, A. Hofmann, S. Reining, B. Eiberger, B. Gabris, A. Pfeifer, A. Welz, K. Willecke, G. Salama, J. W. Schrickel, M. I. Kotlikoff, and B. K. Fleischmann, "Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia," Nature, Vol. 450, (no. 7171), pp. 819-824, 2007.
7. E. S. Boyden, F. Zhang, E. Bamberg, G. Nagel, and K. Deisseroth, "Millisecond-timescale, genetically targeted optical control of neural activity," Nat Neurosci, Vol. 8, (no. 9), pp. 1263-1268, 2005.
8. F. Zhang, A. M. Aravanis, A. Adamantidis, L. de Lecea, and K. Deisseroth, "Circuit-breakers: optical technologies for probing neural signals and systems," Nat Rev Neurosci, Vol. 8, (no. 8), pp. 577-581, 2007.
9. V. Gradinaru, F. Zhang, C. Ramakrishnan, J. Mattis, R. Prakash, I. Diester, I. Goshen, K. R. Thompson, and K. Deisseroth, "Molecular and cellular approaches for diversifying and extending optogenetics," Cell, Vol. 141, (no. 1), pp. 154-165, 2010.
10. R. Balint, N. J. Cassidy, and S. H. Cartmell, "Electrical stimulation: a novel tool for tissue engineering," Tissue engineering. Part B, Reviews, Vol. 19, (no. 1), pp. 48-57, Feb 2013.
11. T. J. Herron, P. Lee, and J. Jalife, "Optical imaging of voltage and calcium in cardiac cells and tissues," Circulation Research, Vol. 110, (no. 4), pp. 609-623, Feb 2012.
12. M. E. Llewellyn, K. R. Thompson, K. Deisseroth, and S. L. Delp, "Orderly recruitment of motor units under optical control in vivo," Nat Med, Vol. 16, (no. 10), pp. 1161-5, Oct 2010.
13. M. S. Sakar, D. Neal, T. Boudou, M. A. Borochin, Y. Li, R. Weiss, R. D. Kamm, C. S. Chen, and H. H. Asada, "Formation and optogenetic control of engineered 3D skeletal muscle bioactuators," Lab Chip, Vol. 12, (no. 23), pp. 4976-85, Dec 2012.
14. T. Bruegmann, D. Malan, M. Hesse, T. Beiert, C. J. Fuegemann, B. K. Fleischmann, and P. Sasse, "Optogenetic control of heart muscle in vitro and in vivo," Nat Meth, Vol. 7, (no. 11), pp. 897-900, 2010.
15. J. P. Weick, M. A. Johnson, S. P. Skroch, J. C. Williams, K. Deisseroth, and S. C. Zhang, "Functional control of transplantable human ESC-derived neurons via optogenetic targeting," Stem Cells, Vol. 28, (no. 11), pp. 2008-16, 2010.
16. O. J. Abilez, J. Wong, R. Prakash, K. Deisseroth, C. K. Zarins, and E. Kuhl, "Multiscale computational models for optogenetic control of cardiac function," Biophysical Journal, Vol. 101, (no. 6), pp. 1326-1334, 2011.
17. A. B. Arrenberg, D. Y. R. Stainier, H. Baier, and J. Huisken, "Optogenetic control of cardiac function," Science, Vol. 330, (no. 6006), pp. 971-974, 2010.
18. J. Wong, O. J. Abilez, and E. Kuhl, "Computational optogenetics: a novel continuum framework for the photoelectrochemistry of living systems," J Mech Physics Solids, Vol. 60, (no. 6), pp. 1158-1178, Jun 2012.
19. O. J. Abilez, "Cardiac optogenetics," IEEE Eng Med Biol Soc, pp. 1386-9, Aug 2012.
20. O. J. Abilez, "Optogenetic LED array for perturbing cardiac electrophysiology," IEEE Engineering in medicine and biology society conference proceedings, Vol. 2013, pp. 1619-1622, 2013.
21. J. B. Bryson, C. B. Machado, M. Crossley, D. Stevenson, V. Bros-Facer, J. Burrone, L. Greensmith, and I. Lieberam, "Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice," Science, Vol. 344, (no. 6179), pp. 94-97, Apr 2014.
22. K. R. Chien, "Regenerative medicine and human models of human disease," Nature, Vol. 453, (no. 7193), pp. 302-305, 2008.
23. Y. Shiba, S. Fernandes, W.-Z. Zhu, D. Filice, V. Muskheli, J. Kim, N. J. Palpant, J. Gantz, K. W. Moyes, H. Reinecke, B. Van Biber, T. Dardas, J. L. Mignone, A. Izawa, R. Hanna, M. Viswanathan, J. D. Gold, M. I. Kotlikoff, N. Sarvazyan, M. W. Kay, C. E. Murry, and M. A. Laflamme, "Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts," Nature, Vol. 489, (no. 7415), pp. 322-325, 2012.