Update on photodynamic treatment for actinic keratosis

Current Problems in Dermatology (Switzerland)

Volumn 46, Issue , 2015, Pages 122-128

  Wiegell, Stine Regin ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; AMINOLEVULINIC ACID METHYL ESTER; PHOTOSENSITIZING AGENT; PLACEBO; METHYL 5-AMINOLEVULINATE;

ACTINIC KERATOSIS; ARTICLE; CARBON DIOXIDE LASER; CRYOSURGERY; CRYOTHERAPY; DAYLIGHT PHOTODYNAMIC THERAPY; HUMAN; LIGHT; MULTICENTER STUDY (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PHASE 4 CLINICAL TRIAL (TOPIC); PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RED LIGHT; SKIN PENETRATION; TRANSDERMAL PATCH; ANALOGS AND DERIVATIVES; KERATOSIS, ACTINIC; LOW LEVEL LASER THERAPY; PHOTOCHEMOTHERAPY; PROCEDURES;

AMINOLEVULINIC ACID; HUMANS; KERATOSIS, ACTINIC; LASER THERAPY; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS;

EID: 84929462942     PISSN: 14215721     EISSN: 16622944     Source Type: Book Series    
DOI: 10.1159/000366548     Document Type: Article

References (39)

1. Wang I: Photodynamic Therapy and Laser-Based Diagnostic Studies of Malignant Tumours; thesis. The Jubileum Institute, Department of Oncology, Lund University Hospital. Lund, 1999.
2. Castano AP, Demidova TN, Hamblin MR: Mechanisms in photodynamic therapy: part three-photosensitizer pharmacokinetics, biodistribution, tumor localization and modes of tumor destruction. Photodiagnosis Photodyn Ther 2005; 2:91-106.
3. Robertson CA, Evans DH, Abrahamse H: Photodynamic therapy (PDT): a short review on cellular mechanisms and cancer research applications for PDT. J Photochem Photobiol B 2009; 96: 1-8.
4. Kennedy JC, Pottier RH: Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy. J Photochem Photobiol B 1992; 14: 275-292.
5. Babilas P, Landthaler M, Szeimies RM: Photodynamic therapy in dermatology. Eur J Dermatol 2006; 16:340-348.
6. de Berker D, McGregor JM, Hughes BR, et al: Guidelines for the management of actinic keratoses. Br J Dermatol 2007; 156:222-230.
7. Stockfleth E, Ferrandiz C, Grob JJ, et al: Development of a treatment algorithm for actinic keratoses: a European consensus. Eur J Dermatol 2008; 18:651-659.
8. Morton C, Campbell S, Gupta G, et al: Intraindividual, right-left comparison of topical methyl aminolaevulinate-photo-dynamic therapy and cryotherapy in subjects with actinic keratoses: a multi-centre, randomized controlled study. Br J Dermatol 2006; 155:1029-1036.
9. Piacquadio DJ, Chen DM, Farber HF, et al: Photodynamic therapy with ami-nolevulinic acid topical solution and visible blue light in the treatment of multiple actinic keratoses of the face and scalp: investigator-blinded, phase 3, multicenter trials. Arch Dermatol 2004; 140:41-46.
10. Tschen EH, Wong DS, Pariser DM, et al: Photodynamic therapy using aminolae-vulinic acid for patients with nonhyper-keratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up. Br J Dermatol 2006; 155:1262-1269.
11. Juzeniene A, Juzenas P, Ma LW, et al: Topical application of 5-aminolaevulinic acid, methyl 5-aminolaevulinate and hexyl 5-aminolaevulinate on normal human skin. Br J Dermatol 2006; 155: 791-799.
12. Fritsch C, Homey B, Stahl W, et al: Preferential relative porphyrin enrichment in solar keratoses upon topical application of delta-aminolevulinic acid methylester. Photochem Photobiol 1998; 68: 218-221.
13. Moan J, Ma LW, Iani V: On the pharma-cokinetics of topically applied 5-ami-nolevulinic acid and two of its esters. Int J Cancer 2001; 92:139-143.
14. Szeimies RM, Karrer S, Radakovic-Fijan S, et al: Photodynamic therapy using topical methyl 5-aminolevulinate compared with cryotherapy for actinic kera-tosis: a prospective, randomized study. J Am Acad Dermatol 2002; 47:258-262.
15. Freeman M, Vinciullo C, Francis D, et al: A comparison of photodynamic therapy using topical methyl aminolevu-linate (Metvix) with single cycle cryo-therapy in patients with actinic keratosis: a prospective, randomized study. J Dermatolog Treat 2003; 14:99-106.
16. Pariser DM, Lowe NJ, Stewart DM, et al: Photodynamic therapy with topical methyl aminolevulinate for actinic kera-tosis: results of a prospective randomized multicenter trial. J Am Acad Dermatol 2003; 48:227-232.
17. Tarstedt M, Rosdahl I, Berne B, et al: A randomized multicenter study to compare two treatment regimens of topical methyl aminolevulinate (Metvix)-PDT in actinic keratosis of the face and scalp. Acta Derm Venereol 2005; 85:424-428.
18. Szeimies RM, Matheson RT, Davis SA, et al: Topical methyl aminolevulinate photodynamic therapy using red light-emitting diode light for multiple actinic keratoses: a randomized study. Derma-tol Surg 2009; 35:586-592.
19. Morton CA, McKenna KE, Rhodes LE, et al: Guidelines for topical photodynamic therapy: update. Br J Dermatol 2008; 159:1245-1266.
20. Braathen LR, Szeimies RM, Basset-Seguin N, et al: Guidelines on the use of photodynamic therapy for nonmelano-ma skin cancer: an international consensus. J Am Acad Dermatol 2007; 56: 125-143.
21. Morton CA, Szeimies RM, Sidoroff A, et al: European guidelines for topical pho-todynamic therapy part 1: treatment delivery and current indications - actinic keratoses, Bowen's disease, basal cell carcinoma. J Eur Acad Dermatol Venereol 2013; 27:536-544.
22. Hauschild A, Stockfleth E, Popp G, et al: Optimization of photodynamic therapy with a novel self-adhesive 5-aminolae-vulinic acid patch: results of two randomized controlled phase III studies. Br J Dermatol 2009; 160:1066-1074.
23. Szeimies RM, Stockfleth E, Popp G, et al: Long-term follow-up of photodynamic therapy with a self-adhesive 5-aminolae-vulinic acid patch: 12 months data. Br J Dermatol 2010; 162:410-414.
24. Dirschka T, Radny P, Dominicus R, et al: Photodynamic therapy with BF-200 ALA for the treatment of actinic kerato-sis: results of a multicentre, randomized, observer-blind phase III study in comparison with a registered methyl-5-ami-nolaevulinate cream and placebo. Br J Dermatol 2012; 166:137-146.
25. Sandberg C, Stenquist B, Rosdahl I, et al: Important factors for pain during pho-todynamic therapy for actinic keratosis. Acta Derm Venereol 2006; 86:404-408.
26. Arits AH, van de Weert MM, Nelemans PJ, et al: Pain during topical photody-namic therapy: uncomfortable and unpredictable. J Eur Acad Dermatol Vene-reol 2010; 24:1452-1457.
27. Waters AJ, Ibbotson SH: Parameters associated with severe pain during pho-todynamic therapy: results of a large Scottish series. Br J Dermatol 2011; 165: 696-698.
28. Grapengiesser S, Ericson M, Gudmunds-son F, et al: Pain caused by photody-namic therapy of skin cancer. Clin Exp Dermatol 2002; 27:493-497.
29. Wiegell SR, Skiveren J, Philipsen PA, et al: Pain during photodynamic therapy is associated with protoporphyrin IX fluorescence and fluence rate. Br J Dermatol 2008; 158:727-733.
30. Serra-Guillen C, Hueso L, Nagore E, et al: Comparative study between cold air analgesia and supraorbital and supra-trochlear nerve block for the management of pain during photodynamic therapy for actinic keratoses of the fron-totemporal zone. Br J Dermatol 2009; 161:353-356.
31. Wiegell SR, Haedersdal M, Philipsen PA, et al: Continuous activation of PpIX by daylight is as effective as and less painful than conventional photodynamic therapy for actinic keratoses; a randomized, controlled, single-blinded study. Br J Dermatol 2008; 158:740-746.
32. Wiegell SR, Haedersdal M, Eriksen P, et al: Photodynamic therapy of actinic keratoses with 8% and 16% methyl amino-laevulinate and home-based daylight exposure: a double-blinded randomized clinical trial. Br J Dermatol 2009; 160: 1308-1314.
33. Wiegell SR, Fabricius S, Stender IM, et al: A randomized, multicentre study of directed daylight exposure times of 1 vs. 2 h in daylight-mediated photody-namic therapy with methyl aminolaevu-linate in patients with multiple thin actinic keratoses of the face and scalp. Br J Dermatol 2011; 164:1083-1090.
34. Wiegell SR, Fabricius S, Gniadecka M, et al: Daylight-mediated photodynamic therapy of moderate to thick actinic keratoses of the face and scalp: a randomized multicentre study. Br J Dermatol 2012; 166:1327-1332.
35. Wiegell SR, Fabricius S, Heydenreich J, et al: Weather conditions and daylight-mediated photodynamic therapy: proto-porphyrin IX-weighted daylight doses measured in six geographical locations. Br J Dermatol 2013; 168:186-191.
36. Manstein D, Herron GS, Sink RK, et al: Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury. Lasers Surg Med 2004; 34:426-438.
37. Haedersdal M, Sakamoto FH, Farinelli WA, et al: Fractional CO(2) laser-assisted drug delivery. Lasers Surg Med 2010; 42:113-122.
38. Haedersdal M, Katsnelson J, Sakamoto FH, et al: Enhanced uptake and photoac-tivation of topical methyl aminolevu-linate after fractional CO2 laser pretreat-ment. Lasers Surg Med 2011; 43: 804-813.
39. Togsverd-Bo K, Haak CS, Thaysen-Pe-tersen D, et al: Intensified photodynam-ic therapy of actinic keratoses with fractional CO2 laser: a randomized clinical trial. Br J Dermatol 2012; 166:1262-1269.