Identification of autoreactive CD8+ T cell responses targeting chromogranin A in humanized NOD mice and type 1 diabetes patients

Clinical Immunology

Volumn 159, Issue 1, 2015, Pages 63-71

  Li, Yi ^a   Zhou, Lina ^a   Li, Yashu ^a   Zhang, Jie ^a   Guo, Binbin ^a   Meng, Gang ^a   Chen, Xiaoling ^a   Zheng, Qian ^b   Zhang, Linlin ^a   Zhang, Mengjun ^a   Wang, Li ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

Author keywords

Chronogranin A; Epitope; Humanized NOD mice; Type 1 diabetes

Indexed keywords

CHROMOGRANIN A; GAMMA INTERFERON; HLA A ANTIGEN; HUMAN CHROMOGRANIN A; INTERLEUKIN 17; MURINE CHROMOGRANIN A; PERFORIN; UNCLASSIFIED DRUG; AUTOANTIGEN; EPITOPE; HLA A2 ANTIGEN; HLA-A*02:01 ANTIGEN; PEPTIDE FRAGMENT;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELLULAR IMMUNITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DIABETIC PATIENT; DNA SYNTHESIS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNODETECTION; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TARGETING; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; ADULT; ANIMAL; AUTOIMMUNITY; CYTOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; PRESCHOOL CHILD; SPLEEN; YOUNG ADULT;

ADOLESCENT; ADULT; ANIMALS; AUTOANTIGENS; AUTOIMMUNITY; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CHILD; CHILD, PRESCHOOL; CHROMOGRANIN A; DIABETES MELLITUS, TYPE 1; EPITOPES, T-LYMPHOCYTE; FEMALE; HLA-A2 ANTIGEN; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-17; MALE; MICE; MICE, INBRED NOD; PEPTIDE FRAGMENTS; PERFORIN; SPLEEN; YOUNG ADULT;

EID: 84929453581     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.04.017     Document Type: Article

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