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Volumn 8, Issue , 2015, Pages 819-825

Profile of nimotuzumab in the treatment of high-grade glioma

Author keywords

Chemotherapy; High grade gliomas; Nimotuzumab; Radiotherapy

Indexed keywords

CETUXIMAB; CISPLATIN; CYCLOPHOSPHAMIDE; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; EVEROLIMUS; GEFITINIB; LAPATINIB; NAVELBINE; NIMOTUZUMAB; NIMUSTINE; PANITUMUMAB; PLACEBO; PREDNISONE; PROCARBAZINE; TEMOZOLOMIDE; TENIPOSIDE;

EID: 84929408366     PISSN: 11786930     EISSN: 11786930     Source Type: Journal    
DOI: 10.2147/OTT.S60032     Document Type: Article
Times cited : (18)

References (22)
  • 1
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987–996.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 2
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10(5):459–466.
    • (2009) Lancet Oncol , vol.10 , Issue.5 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 3
    • 33745761030 scopus 로고    scopus 로고
    • Amplifcation of the epidermal growth factor receptor in astrocytic tumours by chromogenic in situhybridization: Association with clinicopathological features and patient survival
    • Jarvela S, Helin H, Haapasalo J, et al. Amplifcation of the epidermal growth factor receptor in astrocytic tumours by chromogenic in situhybridization: association with clinicopathological features and patient survival. Neuropathol Appl Neurobiol. 2006;32:441–450.
    • (2006) Neuropathol Appl Neurobiol , vol.32 , pp. 441-450
    • Jarvela, S.1    Helin, H.2    Haapasalo, J.3
  • 4
    • 42549104976 scopus 로고    scopus 로고
    • Analysis of EGFR overexpression, EGFR gene amplifcation and the EGFRvIII mutation in Portuguese high-grade gliomas
    • Viana-Pereira M, Lopes JM, Little S, et al. Analysis of EGFR overexpression, EGFR gene amplifcation and the EGFRvIII mutation in Portuguese high-grade gliomas. Anticancer Res. 2008;28:913–920.
    • (2008) Anticancer Res , vol.28 , pp. 913-920
    • Viana-Pereira, M.1    Lopes, J.M.2    Little, S.3
  • 5
    • 77957351780 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis
    • Mazzoleni S, Politi LS, Pala M, et al. Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis. Cancer Res. 2010;70(19):7500–7513.
    • (2010) Cancer Res , vol.70 , Issue.19 , pp. 7500-7513
    • Mazzoleni, S.1    Politi, L.S.2    Pala, M.3
  • 6
    • 27744606737 scopus 로고    scopus 로고
    • Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
    • Mellinghoff IK, Wang MY, Vivanco I, et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med. 2005;353:2012–2024.
    • (2005) N Engl J Med , vol.353 , pp. 2012-2024
    • Mellinghoff, I.K.1    Wang, M.Y.2    Vivanco, I.3
  • 7
    • 77953664765 scopus 로고    scopus 로고
    • Nimotuzumab, a promising therapeutic monoclonal for treatment of tumors of epithelial origin
    • Ramakrishnan MS, Eswaraiah A, Crombet T, et al. Nimotuzumab, a promising therapeutic monoclonal for treatment of tumors of epithelial origin. MAbs. 2009;1(1):41–48.
    • (2009) Mabs , vol.1 , Issue.1 , pp. 41-48
    • Ramakrishnan, M.S.1    Eswaraiah, A.2    Crombet, T.3
  • 8
    • 84880849129 scopus 로고    scopus 로고
    • Nimotuzumab as a radiosensitizing agent in the treatment of high grade glioma: Challenges and opportunities
    • Diaz-Miqueli A, Martinez GS. Nimotuzumab as a radiosensitizing agent in the treatment of high grade glioma: challenges and opportunities. Onco Targets Ther. 2013;6:931–942.
    • (2013) Onco Targets Ther , vol.6 , pp. 931-942
    • Diaz-Miqueli, A.1    Martinez, G.S.2
  • 9
    • 84869449735 scopus 로고    scopus 로고
    • Nimotuzumab treatment of malignant gliomas
    • Bode U, Massimino M, Bach F, et al. Nimotuzumab treatment of malignant gliomas. Expert Opin Biol Ther. 2012;12(12):1649–1659.
    • (2012) Expert Opin Biol Ther , vol.12 , Issue.12 , pp. 1649-1659
    • Bode, U.1    Massimino, M.2    Bach, F.3
  • 10
    • 33646434844 scopus 로고    scopus 로고
    • Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: Report from a phase I/II trial
    • Ramos TC, Figueredo J, Catala M, et al. Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: report from a phase I/II trial. Cancer Biol Ther. 2006;5(4):375–379.
    • (2006) Cancer Biol Ther , vol.5 , Issue.4 , pp. 375-379
    • Ramos, T.C.1    Figueredo, J.2    Catala, M.3
  • 11
    • 0035889349 scopus 로고    scopus 로고
    • Improved efficacy of chemotherapy for glioblastoma by radiation-induced opening of blood-brain barrier: Clinical results
    • Qin D, Ou G, Mo H, et al. Improved efficacy of chemotherapy for glioblastoma by radiation-induced opening of blood-brain barrier: clinical results. Int J Radiat Oncol Biol Phys. 2001;51:959–962.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 959-962
    • Qin, D.1    Ou, G.2    Mo, H.3
  • 12
    • 0032587872 scopus 로고    scopus 로고
    • 99mTc-labeled antihuman epidermal growth factor receptor antibody in patients with tumours of epithelial origin, part II: Clinical trials safety and diagnostic efficacy
    • Ramos-Suzarte M, Rodriguez N, Oliva JP, et al. 99mTc-labeled antihuman epidermal growth factor receptor antibody in patients with tumours of epithelial origin, part II: clinical trials safety and diagnostic efficacy. J Nucl Med. 1999;40:768–775.
    • (1999) J Nucl Med , vol.40 , pp. 768-775
    • Ramos-Suzarte, M.1    Rodriguez, N.2    Oliva, J.P.3
  • 13
    • 84865719997 scopus 로고    scopus 로고
    • Nimotuzumab prolongs survival in patients with malignant gliomas: A phase I/II clinical study of concomitant radiochemotherapy with or without nimotuzumab
    • Hong J, Peng Y, Liao Y, et al. Nimotuzumab prolongs survival in patients with malignant gliomas: a phase I/II clinical study of concomitant radiochemotherapy with or without nimotuzumab. Exp Ther Med. 2012;4(1):151–157.
    • (2012) Exp Ther Med , vol.4 , Issue.1 , pp. 151-157
    • Hong, J.1    Peng, Y.2    Liao, Y.3
  • 14
    • 84930980137 scopus 로고    scopus 로고
    • Phase 2 study of safety and efficacy of nimotuzumab in pediatric patients with progressive diffuse intrinsic pontine glioma
    • May 20
    • Bartels U, Wolff J, Gore L, et al. Phase 2 study of safety and efficacy of nimotuzumab in pediatric patients with progressive diffuse intrinsic pontine glioma. Neuro Oncol. Epub May 20, 2014.
    • (2014) Neuro Oncol. Epub
    • Bartels, U.1    Wolff, J.2    Gore, L.3
  • 16
    • 84899795339 scopus 로고    scopus 로고
    • Nimotuzumab in combination with radiotherapy in high grade glioma patients: A single institution experience
    • Solomon MT, Miranda N, Jorrín E, et al. Nimotuzumab in combination with radiotherapy in high grade glioma patients: a single institution experience. Cancer Biol Ther. 2014;15(5):504–509.
    • (2014) Cancer Biol Ther , vol.15 , Issue.5 , pp. 504-509
    • Solomon, M.T.1    Miranda, N.2    Jorrín, E.3
  • 17
    • 84903899918 scopus 로고    scopus 로고
    • Results of nimotuzumab and vinorelbine, radiation and re-irradiation for diffuse pontine glioma in childhood
    • Massimino M, Biassoni V, Miceli R, et al. Results of nimotuzumab and vinorelbine, radiation and re-irradiation for diffuse pontine glioma in childhood. J Neurooncol. 2014;118(2):305–312.
    • (2014) J Neurooncol , vol.118 , Issue.2 , pp. 305-312
    • Massimino, M.1    Biassoni, V.2    Miceli, R.3
  • 18
    • 84921798224 scopus 로고    scopus 로고
    • Nimotuzumab, a humanized monoclonal antibody specific for the EGFR, in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma multiforme: First results in Chinese patients
    • January 24
    • Wang Y, Pan L, Sheng XF, et al. Nimotuzumab, a humanized monoclonal antibody specific for the EGFR, in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma multiforme: first results in Chinese patients. Asia Pac J Clin Oncol. Epub January 24, 2014.
    • (2014) Asia Pac J Clin Oncol. Epub
    • Wang, Y.1    Pan, L.2    Sheng, X.F.3
  • 19
    • 68649118150 scopus 로고    scopus 로고
    • Clinical experience with nimotuzumab in cuban pediatric patients with brain tumors, 2005 to 2007
    • Saurez G, Cabanas R, Zaldívar M, et al. Clinical experience with nimotuzumab in cuban pediatric patients with brain tumors, 2005 to 2007.MEDICC Rev. 2009;11(3):27–33.
    • (2009) MEDICC Rev. , vol.11 , Issue.3 , pp. 27-33
    • Saurez, G.1    Cabanas, R.2    Zaldívar, M.3
  • 20
    • 84876520122 scopus 로고    scopus 로고
    • Treatment of children with high grade glioma with nimotuzumab: A 5-year institutional experience
    • Cabanas R, Saurez G, Rios M, et al. Treatment of children with high grade glioma with nimotuzumab: a 5-year institutional experience. MAbs. 2013;5(2):202–207.
    • (2013) Mabs , vol.5 , Issue.2 , pp. 202-207
    • Cabanas, R.1    Saurez, G.2    Rios, M.3
  • 21
    • 84879042760 scopus 로고    scopus 로고
    • Radiotherapy plus nimotuzumab or placebo in the treatment of high grade glioma patients: Results from a randomized, double blind trial
    • Solomón J et al. Radiotherapy plus nimotuzumab or placebo in the treatment of high grade glioma patients: results from a randomized, double blind trial. BMC Cancer. 2013;13:299.
    • (2013) BMC Cancer , vol.13 , pp. 299
    • Solomón, J.1
  • 22
    • 84869397010 scopus 로고    scopus 로고
    • Final results of a randomized phase III trial of nimotuzumab for the treatment of newly diagnosed glioblastoma in addition to standard radiation and chemotherapy with temozolomide versus standard radiation and temoziolamide
    • June 1–5, Chicago, IL, USA. J Clin Oncol, Abstr 2033
    • Westphal M, Bach F. Final results of a randomized phase III trial of nimotuzumab for the treatment of newly diagnosed glioblastoma in addition to standard radiation and chemotherapy with temozolomide versus standard radiation and temoziolamide. ASCO Annual Meeting; June 1–5, 2012; Chicago, IL, USA. J Clin Oncol. 30(Suppl):Abstr 2033.
    • (2012) ASCO Annual Meeting , vol.30
    • Westphal, M.1    Bach, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.