ADAMTS7 in cardiovascular disease from bedside to bench and back again?

Circulation

Volumn 131, Issue 13, 2015, Pages 1156-1159

  Arroyo, Alicia G ^a   Andrés, Vicente ^a  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMTS7 PROTEIN; METALLOPROTEINASE; THROMBOSPONDIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ADAM PROTEIN; ADAMTS7 PROTEIN, MOUSE;

AORTA ATHEROSCLEROSIS; EDITORIAL; EXPERIMENTAL ATHEROSCLEROSIS; GENE CASSETTE; GENE DELETION; GENE INACTIVATION; GENETIC ASSOCIATION; HUMAN; NONHUMAN; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; UPREGULATION; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; CAROTID ARTERY INJURY; ENZYMOLOGY; FEMORAL ARTERY; INJURIES; MALE; NEOINTIMA; PHYSIOLOGY; VASCULAR REMODELING;

ADAM PROTEINS; ANIMALS; CAROTID ARTERY INJURIES; FEMORAL ARTERY; HUMANS; MALE; NEOINTIMA; THROMBOSPONDIN 1; VASCULAR REMODELING;

EID: 84929380181     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.015711     Document Type: Editorial

References (20)

1. Shiomi T, Lemaître V, D'Armiento J, Okada Y. Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases. Pathol Int. 2010;60:477-496. doi: 10.1111/j.1440-1827.2010.02547.x.
2. Newby AC. Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc Res. 2006;69:614-624. doi: 10.1016/j.cardiores.2005.08.002.
3. Patel RS, Ye S. ADAMTS7: a promising new therapeutic target in coronary heart disease. Expert Opin Ther Targets. 2013;17:863-867. doi: 10.1517/14728222.2013.816287.
4. Hanby HA, Zheng XL. Biochemistry and physiological functions of ADAMTS7 metalloprotease. Adv Biochem. 2013;1. doi: 10.11648/j.ab.20130103.11.
5. Bauer RC, Tohyama J, Cui J, Cheng L, Yang J, Zhang X, Ou K, Paschos GK, Zheng XL, Parmacek MS, Rader DJ, Reilly MP. Knockout of Adamts7, a novel coronary artery disease locus in humans, reduces atherosclerosis in mice. Circulation. 2015;131:1202-1213.
6. van Setten J, Isgum I, Smolonska J, Ripke S, de Jong PA, Oudkerk M, de Koning H, Lammers JW, Zanen P, Groen HJ, Boezen HM, Postma DS, Wijmenga C, Viergever MA, Mali WP, de Bakker PI. Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction. Atherosclerosis. 2013;228:400-405. doi: 10.1016/j.atherosclerosis.2013.02.039.
7. Andrés V. Control of vascular cell proliferation and migration by cyclin-dependent kinase signalling: new perspectives and therapeutic potential. Cardiovasc Res. 2004;63:11-21. doi: 10.1016/j.cardiores.2004.02.009.
8. Kessler T, Zhang L, Liu Z, Yin X, Huang Y, Wang Y, Fu Y, Mayr M, Ge Q, Xu Q, Zhu Y, Wang X, German Mouse Clinic Consortium Schmidt K, de Wit C, Erdmann J, Schunkert H, Aherrahrou Z, Kong W. Adamts-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling through cleavage of thrombospondin-1. Circulation. 2015;131:1191-1201.
9. Wang L, Zheng J, Bai X, Liu B, Liu CJ, Xu Q, Zhu Y, Wang N, Kong W, Wang X. ADAMTS-7 mediates vascular smooth muscle cell migration and neointima formation in balloon-injured rat arteries. Circ Res. 2009;104:688-698. doi: 10.1161/CIRCRESAHA.108.188425.
10. Chen D, Asahara T, Krasinski K, Witzenbichler B, Yang J, Magner M, Kearney M, Frazier WA, Isner JM, Andrés V. Antibody blockade of thrombospondin accelerates reendothelialization and reduces neointima formation in balloon-injured rat carotid artery. Circulation. 1999;100:849-854.
11. Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C, Patel A, Senver EC, Shaw-Hawkins S, Willeit J, Liu C, Zhu J, Tucker AT, Xu Q, Caulfield MJ, Ye S. ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant. Am J Hum Genet. 2013;92:366-374. doi: 10.1016/j.ajhg.2013.01.012.
12. Lener T, Burgstaller G, Crimaldi L, Lach S, Gimona M. Matrix-degrading podosomes in smooth muscle cells. Eur J Cell Biol. 2006;85:183-189. doi: 10.1016/j.ejcb.2005.08.001.
13. Schachtner H, Calaminus SD, Thomas SG, Machesky LM. Podosomes in adhesion, migration, mechanosensing and matrix remodeling. Cytoskeleton (Hoboken). 2013;70:572-589. doi: 10.1002/cm.21119.
14. Lueders TN, Zou K, Huntsman HD, Meador B, Mahmassani Z, Abel M, Valero MC, Huey KA, Boppart MD. The alpha7beta1-integrin accelerates fiber hypertrophy and myogenesis following a single bout of eccentric exercise. Am J Physiol Cell Physiol. 2011;301:C938-946.
15. Welser JV, Lange N, Singer CA, Elorza M, Scowen P, Keef KD, Gerthoffer WT, Burkin DJ. Loss of the alpha7 integrin promotes extracellular signal-regulated kinase activation and altered vascular remodeling. Circ Res. 2007;101:672-681. doi: 10.1161/CIRCRESAHA.107.151415.
16. Liu CJ, Kong W, Xu K, Luan Y, Ilalov K, Sehgal B, Yu S, Howell RD, Di Cesare PE. ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein. J Biol Chem. 2006;281:15800-15808. doi: 10.1074/jbc.M513433200.
17. Koziol A, Gonzalo P, Mota A, Pollán Á, Lorenzo C, Colomé N, Montaner D, Dopazo J, Arribas J, Canals F, Arroyo AG. The protease MT1-MMP drives a combinatorial proteolytic program in activated endothelial cells. FASEB J. 2012;26:4481-4494. doi: 10.1096/fj.12-205906.
18. Fukumoto Y, Deguchi JO, Libby P, Rabkin-Aikawa E, Sakata Y, Chin MT, Hill CC, Lawler PR, Varo N, Schoen FJ, Krane SM, Aikawa M. Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques. Circulation. 2004;110:1953-1959. doi: 10.1161/01.CIR.0000143174.41810.10.
19. Hoch JM, Mattacola CG, Medina McKeon JM, Howard JS, Lattermann C. Serum cartilage oligomeric matrix protein (sCOMP) is elevated in patients with knee osteoarthritis: a systematic review and meta-analysis. Osteoarthritis Cartilage. 2011;19:1396-1404. doi: 10.1016/j. joca.2011.09.005.
20. Du Y, Gao C, Liu Z, Wang L, Liu B, He F, Zhang T, Wang Y, Wang X, Xu M, Luo GZ, Zhu Y, Xu Q, Wang X, Kong W. Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification. Arterioscler Thromb Vasc Biol. 2012;32:2580-2588. doi: 10.1161/ATVBAHA.112.300206.