Improved sperm count and motility in young men surgically treated for cryptorchidism in the first year of life

European Journal of Pediatric Surgery

Volumn 24, Issue 5, 2014, Pages 376-380

  Feyles, Francesca ^a   Peiretti, Valentina ^a   Mussa, Alessandro ^a   Manenti, Marco ^b   Canavese, Ferdinando ^a   Cortese, Maria Grazia ^a   Lala, Roberto ^a  

^a REGINA MARGHERITA CHILDREN S HOSPITAL   (Italy)

^b Sant'Anna Hospital   (Italy)

Author keywords

cryptorchidism; orchiopexy; sperm analysis; testicular volume

Indexed keywords

CHORIONIC GONADOTROPIN; GONADORELIN;

ADULT; AGE; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; COHORT ANALYSIS; CRYPTORCHISM; EDITORIAL; FERTILITY; HORMONAL THERAPY; HUMAN; MAJOR CLINICAL STUDY; MALE; ORCHIDOPEXY; PROGNOSIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS; TESTIS SIZE; YOUNG ADULT; ADOLESCENT; ANATOMY AND HISTOLOGY; CRYPTORCHIDISM; FOLLOW UP; PHYSIOLOGY;

ADOLESCENT; ADULT; AGE FACTORS; CRYPTORCHIDISM; FOLLOW-UP STUDIES; HUMANS; MALE; SPERM COUNT; SPERM MOTILITY; TESTIS; YOUNG ADULT;

EID: 84929335890     PISSN: 09397248     EISSN: 1439359X     Source Type: Journal    
DOI: 10.1055/s-0033-1349715     Document Type: Editorial

References (24)

1. Kim S. O., Hwang E. C., Hwang I. S., et al. Testicular catch up growth: the impact of orchiopexy age. Urology: 2011; 78 4 886 889
2. Virtanen H. E., Toppari J. Epidemiology and pathogenesis of cryptorchidism. Hum Reprod Update: 2008; 14 1 49 58
3. Rey R. A. Early orchiopexy to prevent germ cell loss during infancy in congenital cryptorchidism. J Clin Endocrinol Metab: 2012; 97 12 4358 4361
4. Trsinar B., Muravec U. R. Fertility potential after unilateral and bilateral orchidopexy for cryptorchidism. World J Urol: 2009; 27 4 513 519
5. Vilar O. Histology of the human testis from neonatal to adolescence. In: Rosenberg E., Paulsen C. A., eds. The Human Testis. New York, NY Plenum Press: 1970; 95
6. Mengel W., Hienz H. A., Sippe W. G. II, Hecker W. C. Studies on cryptorchidism: a comparison of histological findings in the germinative epithelium before and after the second year of life. J Pediatr Surg: 1974; 9 4 445 450
7. Hadziselimovic F. Cryptorchidism. Ultrastructure of normal and cryptorchid testis development. Adv Anat Embryol Cell Biol: 1977; 53 3 3 71
8. Huff D. S., Fenig D. M., Canning D. A., Carr M. G., Zderic S. A., Snyder H. M. III. Abnormal germ cell development in cryptorchidism. Horm Res: 2001; 55 1 11 17
9. Mizuno K., Hayashi Y., Kojima Y., Kurokawa S., Sasaki S., Kohri K. Early orchiopexy improves subsequent testicular development and spermatogenesis in the experimental cryptorchid rat model. J Urol: 2008; 179 3 1195 1199
10. Hadziselimovic F., Herzog B. The importance of both an early orchidopexy and germ cell maturation for fertility. Lancet: 2001; 358 9288 1156 1157
11. Hadziselimovic F., Hocht B., Herzog B., Buser M. W. Infertility in cryptorchidism is linked to the stage of germ cell development at orchidopexy. Horm Res: 2007; 68 1 46 52
12. Hadziselimovic F. Successful treatment of unilateral cryptorchid boys risking infertility with LH-RH analogue. Int Braz J Urol: 2008; 34 3 319 326, discussion 327-328
13. Lala R., Matarazzo P., Chiabotto P., et al. Early hormonal and surgical treatment of cryptorchidism. J Urol: 1997; 157 5 1898 1901
14. Kollin C., Stukenborg J. B., Nurmio M., et al. Boys with undescended testes: endocrine, volumetric and morphometric studies on testicular function before and after orchidopexy at nine months or three years of age. J Clin Endocrinol Metab: 2012; 97 12 4588 4595
15. Huff D. S., Hadziselimovic F., Snyder H. M. III, Duckett J. W., Keating M. A. Postnatal testicular maldevelopment in unilateral cryptorchidism. J Urol: 1989; 142 2 Pt 2 546 548, discussion 572
16. Ritzén E. M., Bergh A., Bjerknes R., et al. Nordic consensus on treatment of undescended testes. Acta Paediatr: 2007; 96 5 638 643
17. Vinardi S., Magro P., Manenti M., et al. Testicular function in men treated in childhood for undescended testes. J Pediatr Surg: 2001; 36 2 385 388
18. Canavese F., Mussa A., Manenti M., et al. Sperm count of young men surgically treated for cryptorchidism in the first and second year of life: fertility is better in children treated at a younger age. Eur J Pediatr Surg: 2009; 19 6 388 391
19. World Health Organisation WHO Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th ed. Cambridge, CA Cambridge University Press: 1999
20. Murphy F., Paran T. S., Puri P. Orchidopexy and its impact on fertility. Pediatr Surg Int: 2007; 23 7 625 632
21. Gracia J., Sánchez Zalabardo J., Sánchez García J., García C., Ferrández A. Clinical, physical, sperm and hormonal data in 251 adults operated on for cryptorchidism in childhood. BJU Int: 2000; 85 9 1100 1103
22. Zhou B., Hutson J. M., Watts L. M., Hasthorpe S. Naim-Ul-Islam. Human chorionic gonadotrophin (hCG) stimulates spermatogenesis in immature mice in vivo. J Pediatr Surg: 2002; 37 12 1751 1753
23. Dunkel L., Taskinen S., Hovatta O., Tilly J. L., Wikström S. Germ cell apoptosis after treatment of cryptorchidism with human chorionic gonadotropin is associated with impaired reproductive function in the adult. J Clin Invest: 1997; 100 9 2341 2346
24. Cortes D., Thorup J., Visfeldt J. Hormonal treatment may harm the germ cells in 1 to 3-year-old boys with cryptorchidism. J Urol: 2000; 163 4 1290 1292