See-through brains and diffusion tensor MRI clarified fiber connections: A preliminary microstructural study in a mouse with callosal agenesis

Magnetic Resonance in Medical Sciences

Volumn 14, Issue 2, 2015, Pages 159-162

  Kerever, Aurelien ^a   Kamagata, Koji ^a   Yokosawa, Suguru ^b   Otake, Yosuke ^b   Ochi, Hisaaki ^b   Yamada, Taihei ^a   Hori, Masaaki ^a   Kamiya, Kouhei ^c   Nishikori, Akira ^d   Aoki, Shigeki ^a   Arikawa Hirasawa, Eri ^a  

^a JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HITACHI LTD   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOKYO METROPOLITAN UNIVERSITY   (Japan)

Author keywords

CLARITY; Cleared brain; CUBIC; Diffusion tensor imaging; Mice

Indexed keywords

ANATOMY AND HISTOLOGY; ANIMAL; BRAIN; BRAIN FORNIX; BRAIN THIRD VENTRICLE; C57BL MOUSE; CONGENITAL MALFORMATION; CORPUS CALLOSUM; CORPUS CALLOSUM AGENESIS; DIFFUSION TENSOR IMAGING; DIFFUSION WEIGHTED IMAGING; DISEASE MODEL; HIPPOCAMPUS; HISTOLOGY; IMAGE PROCESSING; INBRED MOUSE STRAIN; MALE; MICROTOMY; MOUSE; NERVE CELL NETWORK; PATHOLOGY; PROCEDURES; THREE DIMENSIONAL IMAGING; TISSUE FIXATION; WHITE MATTER;

AGENESIS OF CORPUS CALLOSUM; ANIMALS; BRAIN; CORPUS CALLOSUM; DIFFUSION MAGNETIC RESONANCE IMAGING; DIFFUSION TENSOR IMAGING; DISEASE MODELS, ANIMAL; FORNIX, BRAIN; HIPPOCAMPUS; HISTOCYTOLOGICAL PREPARATION TECHNIQUES; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICROTOMY; NERVE NET; THIRD VENTRICLE; TISSUE FIXATION; WHITE MATTER;

EID: 84929331609     PISSN: 13473182     EISSN: 18802206     Source Type: Journal    
DOI: 10.2463/mrms.2014-0142     Document Type: Article

References (12)

1. Chung K, Wallace J, Kim SY, et al. Structural and molecular interrogation of intact biological systems. Nature 2013; 497:332–337.
2. Susaki EA, Tainaka K, Perrin D, et al. Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis. Cell 2014; 157:726–739.
3. Basser PJ, Mattiello J, LeBihan D. Estimation of the effective self-diffusion tensor from the NMR spin echo. J Magn Reson B 1994; 103:247–254.
4. Kamagata K, Shimoji K, Hori M, et al Intersite reliability of diffusion tensor imaging on two 3T scanners. Magn Reson Med Sci 2015 Feb 12. [Epub ahead of print]
5. Scattoni ML, Ricceri L, Crawley JN. Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters. Genes Brain Behav 2011; 10:44–56.
6. Miller VM, Gupta D, Neu N, Cotroneo A, Boulay CB, Seegal RF. Novel inter-hemispheric white matter connectivity in the BTBR mouse model of autism. Brain Res 2013; 1513:26–33.
7. Wahlsten D, Metten P, Crabbe JC. Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum. Brain Res 2003; 971:47–54.
8. Dodero L, Damiano M, Galbusera A, et al. Neuro-imaging evidence of major morpho-anatomical and functional abnormalities in the BTBR T+TF/J mouse model of autism. PLoS One 2013; 8:e76655.
9. Masutani Y, Aoki S, Abe O, Hayashi N, Otomo K. MR diffusion tensor imaging: recent advance and new techniques for diffusion tensor visualization. Eur J Radiol 2003; 46:53–66.
10. Mori S, Crain BJ, Chacko VP, van Zijl PC. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol 1999; 45:265–269.
11. Wyss JM, Swanson LW, Cowan WM. The organization of the fimbria, dorsal fornix and ventral hippo-campal commissure in the rat. Anat Embryol (Berl) 1980; 158:303–316.
12. Wiegell MR, Larsson HB, Wedeen VJ. Fiber crossing in human brain depicted with diffusion tensor MR imaging. Radiology 2000; 217:897–903.