Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms

Journal of Hematology and Oncology

Volumn 7, Issue 1, 2015, Pages

  Schneider, Rebekka K ^a,b   Ziegler, Susanne ^b   Leisten, Isabelle ^b   Ferreira, Monica S V ^b   Schumacher, Anne ^b   Rath, Björn ^b   Fahrenkamp, Dirk ^b   Müller Newen, Gerhard ^b   Crysandt, Martina ^b   Wilop, Stefan ^b   Jost, Edgar ^b   Koschmieder, Steffen ^b   Knüchel, Ruth ^b   Brümmendorf, Tim H ^b   Ziegler, Patrick ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Fibronectin; Mesenchymal stromal cells; Myelofibrosis; Myeloproliferative neoplasms; Tissue microarray biomarker

Indexed keywords

FIBRONECTIN; HEMOGLOBIN; RETICULIN;

ARTICLE; BONE MARROW BIOPSY; BONE MARROW STROMA CELL; CONTROLLED STUDY; CORRELATIONAL STUDY; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN CELL; MESENCHYMAL STROMA CELL; MYELOFIBROSIS; MYELOPROLIFERATIVE NEOPLASM; PHENOTYPE; PROTEIN EXPRESSION; GENETICS; METABOLISM; MYELOPROLIFERATIVE DISORDER; PATHOLOGY; TISSUE MICROARRAY;

FIBRONECTINS; HUMANS; MESENCHYMAL STROMAL CELLS; MYELOPROLIFERATIVE DISORDERS; PHENOTYPE; TISSUE ARRAY ANALYSIS;

EID: 84929320581     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-014-0092-2     Document Type: Article

References (6)

1. Kramann R, Couson SK, Neuss S, Kunter U, Bovi M, Bornemann J, Knuchel R, Jahnen-Dechent W, Floege J, Schneider RK: Exposure to uremic serum induces a procalcific phenotype in human mesenchymal stem cells. Arterioscler Thromb Vasc Biol 2011, 31(9):e45-54.
2. Schneider RK, Puellen A, Kramann R, Raupach K, Bornemann J, Knuechel R, Perez-Bouza A, Neuss S: The osteogenic differentiation of adult bone marrow and perinatal umbilical mesenchymal stem cells and matrix remodelling in three-dimensional collagen scaffolds. Biomaterials 2010, 31(3):467-480.
3. Manz MG, Miyamoto T, Akashi K, Weissman IL: Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A 2002, 99(18):11872-11877.
4. Tormin A, Li O, Brune JC, Walsh S, Schutz B, Ehinger M, Ditzel N, Kassem M, Scheding S: CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization. Blood 2011, 117(19):5067-5077.
5. Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Cote D, Rowe DW, Lin CP, Scadden DT: Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature 2009, 457(7225):92-96.
6. Thiele J, Kvasnicka HM, Facchetti F, Franco V, van der Walt J, Orazi A: European consensus on grading bone marrow fibrosis and assessment of cellularity. Haematologica 2005, 90(8):1128-1132.