Association between cytotoxic T-lymphocyte antigen-4 +49A/G polymorphism and colorectal cancer risk: A meta-analysis

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 3, 2015, Pages 3752-3760

  He, Lei ^a   Deng, Tao ^a   Luo, He Sheng ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Colorectal cancer; CTLA 4; Meta analysis; Polymorphism

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4;

ARTICLE; CANCER RISK; COLORECTAL CANCER; ETHNICITY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; META ANALYSIS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SENSITIVITY ANALYSIS;

EID: 84929303853     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Brenner H, Kloor M, Pox CP. Colorectal cancer. Lancet 2014; 383: 1490-1502.
2. Risch N. The genetic epidemiology of cancer: interpreting family and twin studies and their implications for molecular genetic approaches. Cancer Epidemiol Biomarkers Prev 2001; 10: 733-741.
3. Lynch HT, de la Chapelle A. Hereditary colorectal cancer. N Engl J Med 2003; 348: 919-932.
4. Huxley RR, Ansary-Moghaddam A, Clifton P, Czernichow S, Parr CL, Woodward M. The impact of dietary and lifestyle risk factors on risk of colorectal cancer: a quantitative overview of the epidemiological evidence. Int J Cancer 2009; 125: 171-180.
5. Teft WA, Kirchhof MG, Madrenas J. A molecular perspective of CTLA-4 function. Annu Rev Immunol 2006; 24: 65-97.
6. Scheipers P, Reiser H. Fas-independent death of activated CD4 (+) T lymphocytes induced by CTLA-4 cross-linking. Proc Natl Acad Sci U S A 1998; 95: 10083-10088.
7. Sun T, Zhou Y, Yang M, Hu Z, Tan W, Han X, Shi Y, Yao J, Guo Y, Yu D, Tian T, Zhou X, Shen H, Lin D. Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer. Cancer Res 2008; 68: 7025-7034.
8. Ligers A, Teleshova N, Masterman T, Huang WX, Hillert J. CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms. Genes Immun 2001; 2: 145-152.
9. Nisticò L, Buzzetti R, Pritchard LE, Van der Auwera B, Giovannini C, Bosi E, Larrad MT, Rios MS, Chow CC, Cockram CS, Jacobs K, Mijovic C, Bain SC, Barnett AH, Vandewalle CL, Schuit F, Gorus FK, Tosi R, Pozzilli P, Todd JA. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum Mol Genet 1996; 5: 1075-1080.
10. Harper K, Balzano C, Rouvier E, Mattei MG, Luciani MF, Golstein P. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J Immunol 1991; 147: 1037-1044.
11. Cozar JM, Romero JM, Aptsiauri N, Vazquez F, Vilchez JR, Tallada M, Garrido F, Ruiz-Cabello F. High incidence of CTLA-4 AA (CT60) polymorphism in renal cell cancer. Hum Immunol 2007; 68: 698-704.
12. Cui JY, Ma H, Cui WL, Ma WH, Qi YQ. Association of cytotoxic T lymphocyte antigen-4 gene polymorphism with susceptibility on colorectal cancer. Chin J Curr Adv Gen Surg 2013; 16: 127-130.
13. Dilmec F, Ozgonul A, Uzunkoy A, Akkafa F. Investigation of CTLA-4 and CD28 gene polymorphisms in a group of Turkish patients with colorectal cancer. Int J Immunogenet 2008; 35: 317-321.
14. Fan ZG, Fu J, Chen T, Wang GJ. A study of relationship between cytotoxic T lymphocyte antigen-4 +49A>G gene polymorphism and colorectal cancer. Heilongjiang Medical Jounal 2012; 36: 810-811.
15. Hadinia A, Hossieni SV, Erfani N, Saberi-Firozi M, Fattahi MJ, Ghaderi A. CTLA-4 gene promoter and exon 1 polymorphisms in Iranian patients with gastric and colorectal cancers. J Gastroenterol Hepatol 2007; 22: 2283-2287.
16. Li XD, Zhao JP, Sun YY. Relationship between cytotoxic T lymphocyte associated antigen-4 +49A>G gene polymorphism and colorectal cancer in Chinese. Chin J Biologicals 2011; 24: 1038-1041.
17. Qi P, Ruan CP, Wang H, Zhou FG, Xu XY, Gu X, Zhao YP, Dou TH, Gao CF. CTLA-4 +49A>G polymorphism is associated with the risk but not with the progression of colorectal cancer in Chinese. Int J Colorectal Dis 2010; 25: 39-45.
18. Solerio E, Tappero G, Iannace L, Matullo G, Ayoubi M, Parziale A, Cicilano M, Sansoè G, Framarin L, Vineis P, Rosina F. CTLA4 gene polymorphism in Italian patients with colorectal adenoma and cancer. Dig Liver Dis 2005; 37: 170-175.
19. Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med 1997; 127: 820-826.
20. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-748.
21. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88.
22. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50: 1088-1101.
23. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629-634.
24. Geng R, Song F, Yang X, Sun P, Hu J, Zhu C, Zhu B, Fan W. Association between cytotoxic T lymphocyte antigen-4 +49A/G, -1722T/C, and -1661A/G polymorphisms and cancer risk: a meta-analysis. Tumour Biol 2013; 35: 3627-3639.
25. Zhang Y, Zhang J, Deng Y, Tian C, Li X, Huang J, Fan H. Polymorphisms in the cytotoxic T-lymphocyte antigen 4 gene and cancer risk: a meta-analysis. Cancer 2011; 117: 4312-4324.
26. Zheng J, Yu X, Jiang L, Xiao M, Bai B, Lu J, Zhou Y. Association between the Cytotoxic T-lym-phocyte antigen 4 +49G>A polymorphism and cancer risk: a meta-analysis. BMC Cancer 2010; 10: 522.
27. Cheng XL, Ning T, Xu CQ, Li Y, Zhu BS, Hou FT, Zhang SY, Chen ZP. Haplotype analysis of CTLA4 gene and risk of esophageal squamous cell carcinoma in Anyang area of China. Hepatogastroenterology 2011; 58: 432-437.
28. Hou R, Cao B, Chen Z, Li Y, Ning T, Li C, Xu C, Chen Z. Association of cytotoxic T lymphocyte-associated antigen-4 gene haplotype with the susceptibility to gastric cancer. Mol Biol Rep 2010; 37: 515-520.
29. Yang M, Sun T, Zhou Y, Wang L, Liu L, Zhang X, Tang X, Zhou M, Kuang P, Tan W, Li H, Yuan Q, Yu D. The functional cytotoxic T lymphocyte-associated protein 4 49G-to-a genetic variant and risk of pancreatic cancer. Cancer 2012; 118: 4681-4686.
30. Hu L, Liu J, Chen X, Zhang Y, Liu L, Zhu J, Chen J, Shen H, Qiang F, Hu Z. CTLA-4 gene polymorphism +49 A/G contributes to genetic susceptibility to two infection-related cancers-hepatocellular carcinoma and cervical cancer. Hum Immunol 2010; 71: 888-891.
31. Sun T, Hu Z, Shen H, Lin D. Genetic polymorphisms in cytotoxic T-lymphocyte antigen 4 and cancer: the dialectical nature of subtle human immune dysregulation. Cancer Res 2009; 69: 6011-6014.
32. Hirschhorn JN, Lohmueller K, Byrne E, Hirschhorn K. A comprehensive review of genetic association studies. Genet Med 2002; 4: 45-61.
33. Boccia S, De Feo E, Gallì P, Gianfagna F, Amore R, Ricciardi G. A systematic review evaluating the methodological aspects of meta-analyses of genetic association studies in cancer research. Eur J Epidemiol 2010; 25: 765-775.