Fibronectin: Extra domain brings extra risk?

Blood

Volumn 125, Issue 20, 2015, Pages 3043-3044

  Wang, Yiming ^a,b   Ni, Heyu ^a,b  

^a St Michael's Hospital   (United States)

^b CANADIAN BLOOD SERVICES   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA PRECURSOR; TOLL LIKE RECEPTOR 4; VON WILLEBRAND FACTOR;

BLOOD CLOTTING; BONE MARROW TRANSPLANTATION; CIRCULATION; EMBRYO DEVELOPMENT; EXTRACELLULAR MATRIX; EXTRACELLULAR TRAP; HEMOSTASIS; INNATE IMMUNITY; LIVER CELL; NATURAL SELECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; RISK ASSESSMENT; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE; VASCULARIZATION; WOUND HEALING; ANIMAL; FEMALE; MALE; METABOLISM; THROMBOCYTE; THROMBOSIS;

ANIMALS; BLOOD PLATELETS; FEMALE; FIBRONECTINS; MALE; THROMBOSIS; TOLL-LIKE RECEPTOR 4;

EID: 84929303831     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-03-630855     Document Type: Review

References (10)

1. Prakash P, Kulkarni PP, Lentz SR, Chauhan AK. Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4. Blood. 2015; 125(20):3164-3172.
2. Cho J, Mosher DF. Role of fibronectin assembly in platelet thrombus formation. J Thromb Haemost. 2006; 4(7): 1461-1469.
3. Hynes RO. Fibronectins. New York, NY: Springer Verlag; 1990.
4. Ni H, Yuen PS, Papalia JM, et al. Plasma fibronectin promotes thrombus growth and stability in injured arterioles. Proc Natl Acad Sci USA. 2003; 100(5): 2415-2419.
5. Reheman A, Yang H, Zhu G, et al. Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor. Blood. 2009; 113(8):1809-1817.
6. Wang Y, Reheman A, Spring CM, et al. Plasma fibronectin supports hemostasis and regulates thrombosis. J Clin Invest. 2014; 124(10):4281-4293.
7. Chauhan AK, Kisucka J, Cozzi MR, et al. Prothrombotic effects of fibronectin isoforms containing the EDA domain. Arterioscler Thromb Vasc Biol. 2008; 28(2):296-301.
8. Maurer E, Receveur N, Bourdon C, et al. Integrin a5b1 and glycoprotein VI play important roles in mediating activation and aggregation of platelets adhering to fibrillar fibronectin. In: Proceedings from the XXIV Congress of International Society on Thrombosis and Haemostasis (ISTH); June 29-July 4, 2013; Amsterdam, The Netherlands. Abstract OC 87.3.
9. Clark SR, Ma AC, Tavener SA, et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med. 2007; 13(4):463-469.
10. Ni H, Papalia JM, Degen JL, Wagner DD. Control of thrombus embolization and fibronectin internalization by integrin aIIbb3 engagement of the fibrinogen g chain. Blood. 2003; 102(10):3609-3614.