Dose-intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma: A randomized phase II study

British Journal of Haematology

Volumn 169, Issue 5, 2015, Pages 672-682

  Ishida, Takashi ^a   Jo, Tatsuro ^b   Takemoto, Shigeki ^c   Suzushima, Hitoshi ^d   Uozumi, Kimiharu ^e   Yamamoto, Kazuhito ^f   Uike, Naokuni ^c   Saburi, Yoshio ^g   Nosaka, Kisato ^h   Utsunomiya, Atae ⁱ   Tobinai, Kensei ^j   Fujiwara, Hiroshi ^k   Ishitsuka, Kenji ^l   Yoshida, Shinichiro ^m   Taira, Naoya ⁿ   Moriuchi, Yukiyoshi ^o   Imada, Kazunori ^p   Miyamoto, Toshihiro ^q   Akinaga, Shiro ^r   Tomonaga, Masao ^b   Ueda, Ryuzo ^s   more..

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b JAPANESE RED CROSS NAGASAKI GENBAKU HOSPITAL   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION   (Japan)

^d Kumamoto Shinto General Hospital   (Japan)

^e KAGOSHIMA UNIVERSITY HOSPITAL   (Japan)

^f AICHI CANCER CENTER HOSPITAL   (Japan)

^g OITA PREFECTURAL HOSPITAL   (Japan)

^h KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

ⁱ IMAMURA BUN IN HOSPITAL   (Japan)

^j NATIONAL CANCER CENTER HOSPITAL   (Japan)

^k EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^l FUKUOKA UNIVERSITY   (Japan)

^m NATIONAL HOSPITAL ORGANIZATION NAGASAKI MEDICAL CENTER   (Japan)

ⁿ Heart Life Hospital   (Japan)

^o Sasebo Shiritsu Sogo Hospital   (Japan)

^p KOKURA MEMORIAL HOSPITAL   (Japan)

^q KYUSHU UNIVERSITY   (Japan)

^r KYOWA HAKKO KOGYO CO LTD   (Japan)

^s AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

more..

Author keywords

Adult T cell leukaemia lymphoma; Antibody therapy; CCR4; Mogamulizumab; Randomized phase II study

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; MOGAMULIZUMAB; PHOSPHORUS; POTASSIUM; PREDNISOLONE; RANIMUSTINE; SODIUM; VINCRISTINE; VINDESINE; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY; NITROSOUREA DERIVATIVE;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ANEMIA; ARTICLE; BACTEREMIA; BLOOD PRESSURE; CANCER COMBINATION CHEMOTHERAPY; CLINICAL PROTOCOL; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DECREASED APPETITE; DRUG DOSE INTENSIFICATION; DRUG SAFETY; ERYTHEMA; FEBRILE NEUTROPENIA; FEMALE; FEVER; GASTROINTESTINAL SYMPTOM; HEMATOLOGIC DISEASE; HUMAN; HYPERGLYCEMIA; HYPOKALEMIA; HYPONATREMIA; HYPOPHOSPHATEMIA; IMMUNOGENICITY; INFECTION; INFESTATION; INTERSTITIAL LUNG DISEASE; LEUKOPENIA; LYMPHOCYTOPENIA; MALE; MAXIMUM PLASMA CONCENTRATION; MEDIASTINUM DISEASE; METABOLIC DISORDER; MINIMUM PLASMA CONCENTRATION; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; NUTRITIONAL DISORDER; OXYGEN SATURATION; PAPULAR RASH; PHASE 2 CLINICAL TRIAL; PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE; SKIN DISEASE; STOMATITIS; T CELL LEUKEMIA; T LYMPHOCYTE; THORAX DISEASE; THROMBOCYTOPENIA; VIRUS PNEUMONIA; CLINICAL TRIAL; DISEASE COURSE; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MIDDLE AGED; MORTALITY; PATHOLOGY; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARBOPLATIN; CYCLOPHOSPHAMIDE; DISEASE PROGRESSION; DOXORUBICIN; ETOPOSIDE; FEMALE; HUMANS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MALE; MIDDLE AGED; NITROSOUREA COMPOUNDS; PREDNISOLONE; TREATMENT OUTCOME; VINCRISTINE; VINDESINE;

EID: 84929281395     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13338     Document Type: Article

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