Mortality and neurological outcome in the elderly after target temperature management for out-of-hospital cardiac arrest

Resuscitation

Volumn 91, Issue , 2015, Pages 92-98

  Winther Jensen, Matilde ^a   Pellis, Tommaso ^b   Kuiper, Michael ^c   Koopmans, Matty ^c   Hassager, Christian ^a   Nielsen, Niklas ^d   Wetterslev, Jørn ^e   Cronberg, Tobias ^f   Erlinge, David ^g   Friberg, Hans ^g   Gasche, Yvan ^h   Horn, Janneke ⁱ   Hovdenes, Jan ^j   Stammet, Pascal ^k   Wanscher, Michael ^a   Wise, Matthew P ^l   Åneman, Anders ^m   Kjaergaard, Jesper ^a  

^a Mental Health Services CPH   (Denmark)

^b AO Santa Maria Degli Angeli di Pordenone   (Italy)

^c Intensive Care Unit   (Netherlands)

^d HELSINGBORG HOSPITAL   (Sweden)

^e Rigshospitalet   (Denmark)

^f LUND UNIVERSITY   (Sweden)

^g LUND UNIVERSITY HOSPITAL   (Sweden)

^h GENEVA UNIVERSITY HOSPITALS   (Switzerland)

ⁱ ACADEMIC MEDICAL CENTER   (Netherlands)

^j OSLO UNIVERSITY HOSPITAL   (Norway)

^k CENTRE HOSPITALIER DE LUXEMBOURG   (Luxembourg)

^l UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^m LIVERPOOL HOSPITAL   (Australia)

more..

Author keywords

Age; Out of hospital cardiac arrest; Therapeutic hypothermia

Indexed keywords

ADVERSE OUTCOME; AGED; ARTICLE; CARDIOVASCULAR MORTALITY; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; GROUPS BY AGE; HEALTH CARE MANAGEMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; OUT OF HOSPITAL CARDIAC ARREST; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RANKIN SCALE; RESUSCITATION; ST SEGMENT ELEVATION; TARGET TEMPERATURE MANAGEMENT; TASK PERFORMANCE; TEMPERATURE; VERY ELDERLY; AGE; INDUCED HYPOTHERMIA; MIDDLE AGED; MORTALITY; OUT-OF-HOSPITAL CARDIAC ARREST; PROCEDURES; PROGNOSIS; REGRESSION ANALYSIS; SURVIVAL; TREATMENT OUTCOME;

AGE FACTORS; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; HYPOTHERMIA, INDUCED; MALE; MIDDLE AGED; OUT-OF-HOSPITAL CARDIAC ARREST; PROGNOSIS; REGRESSION ANALYSIS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84929262467     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2014.12.030     Document Type: Article

References (38)

1. Langhelle A., Nolan J., Herlitz J., et al. Recommended guidelines for reviewing, reporting, and conducting research on post-resuscitation care: the Utstein style. Resuscitation 2005, 66:271-283.
2. Holzer M., Cerchiari E., Martens P., Roine R.S.F. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002, 346:549-556.
3. Bernard S.A., Gray T.W., Buist M.D., et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002, 346:557-563.
4. Grimaldi D., Dumas F., Perier M.-C., et al. Short- and long-term outcome in elderly patients after out-of-hospital cardiac arrest: a cohort study. Crit Care Med 2014, 1-8.
5. United Nations World Population Ageing 1950-2050 2002, vol. 26.
6. Wissenberg M., Lippert F.K., Folke F., et al. Association of national initiatives to improve cardiac arrest management with rates of bystander intervention and patient survival after out-of-hospital cardiac arrest. JAMA 2013, 310:1377-1384.
7. Yan R.T., Yan A.T., Tan M., et al. Age-related differences in the management and outcome of patients with acute coronary syndromes. Am Heart J 2006, 151:352-359.
8. Bagnall A.J., Goodman S.G., Fox K.A.A., et al. Influence of age on use of cardiac catheterization and associated outcomes in patients with non-ST-elevation acute coronary syndromes. Am J Cardiol 2009, 103:1530-1536.
9. Nielsen N., Wetterslev J., Cronberg T., et al. Targeted temperature management at 33°C versus 36°C after cardiac arrest. N Engl J Med 2013, 369:2197-2206.
10. Nielsen N., Wetterslev J., Cronberg T., et al. Supplement to: targeted temperature management at 33°C versus 36°C after cardiac arrest. N Engl J Med 2013, 369:2197-2206. 10.1056/NEJMoa1310519.
11. Nielsen N., Hovdenes J., Bishop G., et al. Target temperature management after out-of-hospital cardiac arrest - a randomized, parallel-group, assessor-blinded clinical trial - rationale and design. Am Heart J 2012, 163:541-548.
12. R. Foundation for Statistical Computing. R.3.01, R Core Team 2013, http://www.R-project.org/.
13. Nielsen N., Friberg H., Gluud C., Herlitz J., Wetterslev J. Hypothermia after cardiac arrest should be further evaluated - a systematic review of randomised trials with meta-analysis and trial sequential analysis. Int J Cardiol 2011, 151:333-341.
14. Walters J.H., Morley P.T., Nolan J.P. The role of hypothermia in post-cardiac arrest patients with return of spontaneous circulation: a systematic review. Resuscitation 2011, 82:508-516.
15. Busch M., Søreide E. Should advanced age be a limiting factor in providing therapeutic hypothermia to cardiac arrest survivors? A single-center observational study. Ther Hypothermia Temp Manag 2011, 1:29-32. 10.1089/ther.2010.0006..
16. Nielsen N., Hovdenes J., Nilsson F., et al. Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest. Acta Anaesthesiol Scand 2009, 53:926-934.
17. Hayakawa K., Tasaki O., Hamasaki T., et al. Prognostic indicators and outcome prediction model for patients with return of spontaneous circulation from cardiopulmonary arrest: the Utstein Osaka project. Resuscitation 2011, 82:874-880.
18. Herlitz J., Eek M., Engdahl J., Holmberg M., Holmberg S. Factors at resuscitation and outcome among patients suffering from out of hospital cardiac arrest in relation to age. Resuscitation 2003, 58:309-317. 10.1016/S0300-9572(03)00155-2..
19. Herlitz J., Svensson L., Engdahl J., et al. Characteristics of cardiac arrest and resuscitation by age group: an analysis from the Swedish Cardiac Arrest Registry. Am J Emerg Med 2007, 25:1025-1031. 10.1016/j.ajem.2007.03.008..
20. Pleskot M., Hazukova R., Stritecka H., Cermakova E. Five-year survival of patients after out-of-hospital cardiac arrest depending on age. Arch Gerontol Geriatr 2011, 53:e88-e92. 10.1016/j.archger.2010.06.021..
21. Seder D.B., Patel N., McPherson J., et al. Geriatric experience following cardiac arrest at six interventional cardiology centers in the United States 2006-2011: interplay of age, do-not-resuscitate order, and outcomes. Crit Care Med 2014, 42:289-295. 10.1097/CCM.0b013e3182a26ec6..
22. Bunch T.J., White R.D., Khan A.H., Packer D.L. Impact of age on long-term survival and quality of life following out-of-hospital cardiac arrest. Crit Care Med 2004, 32:963-967. 10.1097/01.CCM.0000119421.73520.B6..
23. Knoflach M., Matosevic B., Rücker M., et al. Functional recovery after ischemic stroke - a matter of age: data from the Austrian Stroke Unit Registry. Neurology 2012, 78:279-285.
24. Lindner T., Langørgen J., Sunde K., et al. Factors predicting the use of therapeutic hypothermia and survival in unconscious out-of-hospital cardiac arrest patients admitted to the ICU. Crit Care 2013, 17:R147. 10.1186/cc12826..
25. Peterson E.D., Alexander K.P., Malenka D.J., et al. Multicenter experience in revascularization of very elderly patients. Am Heart J 2004, 148:486-492.
26. Sidhu R.B., Brown J.R., Robb J.F., et al. Interaction of gender and age on post cardiac catheterization contrast-induced acute kidney injury. Am J Cardiol 2008, 102:1482-1486. 10.1016/j.amjcard.2008.07.037..
27. Teodorescu C., Reinier K., Dervan C., et al. Factors associated with pulseless electric activity versus ventricular fibrillation: the Oregon sudden unexpected death study. Circulation 2010, 122:2116-2122. 10.1161/CIRCULATIONAHA.110.966333..
28. Bro-Jeppesen J., Kjaergaard J., Wanscher M., et al. Emergency coronary angiography in comatose cardiac arrest patients: do real-life experiences support the guidelines?. Eur Hear J Acute Cardiovasc Care 2012, 1:291-301. 10.1177/2048872612465588..
29. Hamm C.W., Bassand J-P., Agewall S., et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: the task force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation. Eur Heart J 2011, 32:2999-3054.
30. Epstein A.E., DiMarco J.P., Ellenbogen K.A., et al. ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/N). Circulation 2008, 117:2820-2840.
31. Tung P., Albert C.M. Causes and prevention of sudden cardiac death in the elderly. Nat Rev Cardiol 2013, 10:135-142. 10.1038/nrcardio.2012.201..
32. Becker L.B., Aufderheide T.P., Geocadin R.G., et al. Primary outcomes for resuscitation science studies: a consensus statement from the American Heart Association. Circulation 2011, 124:2158-2177.
33. Hsu J.W., Madsen C.D., Callaham M.L. Quality-of-life and formal functional testing of survivors of out-of-hospital cardiac arrest correlates poorly with traditional neurologic outcome scales. Ann Emerg Med 1996, 28:597-605.
34. Rittenberger J.C., Raina K., Holm M.B., Kim Y.J., Callaway C.W. Association between cerebral performance category, modified Rankin scale, and discharge disposition after cardiac arrest. Resuscitation 2011, 82:1036-1040. 10.1016/j.resuscitation.2011.03.034..
35. Raina K.D., Callaway C., Rittenberger J.C., Holm M.B. Neurological and functional status following cardiac arrest: method and tool utility. Resuscitation 2008, 79:249-256.
36. Bath P.M.W., Lees K.R., Schellinger P.D., et al. Statistical analysis of the primary outcome in acute stroke trials. Stroke 2012, 43:1171-1178.
37. Sprung C.L., Artigas A., Kesecioglu J., et al. The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: Intensive care benefit for the elderly. Crit Care Med 2012, 40:132-138.
38. Garrouste-Orgeas M., Boumendil A., Pateron D., et al. Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria: an observational, multicenter, prospective study. Crit Care Med 2009, 37:2919-2928.