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Volumn 10, Issue 3, 2016, Pages 193-202

Antipsychotic-induced weight gain in first-episode psychosis patients: A meta-analysis of differential effects of antipsychotic medications

Author keywords

Ethnicity; Haloperidol; Obesity; Schizophrenia; Side effect

Indexed keywords

AMISULPRIDE; ARIPIPRAZOLE; BLONANSERIN; CHLORPROMAZINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; PERPHENAZINE; QUETIAPINE; RISPERIDONE; ZIPRASIDONE;

EID: 84929259258     PISSN: 17517885     EISSN: 17517893     Source Type: Journal    
DOI: 10.1111/eip.12251     Document Type: Review
Times cited : (131)

References (62)
  • 1
    • 68949101413 scopus 로고    scopus 로고
    • The unchanging mortality gap for people with schizophrenia
    • Chwastiak LA, Tek C. The unchanging mortality gap for people with schizophrenia. Lancet 2009; 374: 590-592.
    • (2009) Lancet , vol.374 , pp. 590-592
    • Chwastiak, L.A.1    Tek, C.2
  • 2
    • 68949172254 scopus 로고    scopus 로고
    • 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
    • Tiihonen J, Lonnqvist J, Wahlbeck K etal. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet 2009; 374: 620-627.
    • (2009) Lancet , vol.374 , pp. 620-627
    • Tiihonen, J.1    Lonnqvist, J.2    Wahlbeck, K.3
  • 3
    • 84870050297 scopus 로고    scopus 로고
    • Cardiovascular morbidity, mortality and pharmacotherapy in patients with schizophrenia
    • Lahti M, Tiihonen J, Wildgust H etal. Cardiovascular morbidity, mortality and pharmacotherapy in patients with schizophrenia. Psychol Med 2012; 42: 2275-2285.
    • (2012) Psychol Med , vol.42 , pp. 2275-2285
    • Lahti, M.1    Tiihonen, J.2    Wildgust, H.3
  • 4
    • 84875935853 scopus 로고    scopus 로고
    • Cardiovascular mortality in schizophrenia: defining a critical period for prevention
    • Srihari VH, Phutane VH, Ozkan B etal. Cardiovascular mortality in schizophrenia: defining a critical period for prevention. Schizophr Res 2013; 146: 64-68.
    • (2013) Schizophr Res , vol.146 , pp. 64-68
    • Srihari, V.H.1    Phutane, V.H.2    Ozkan, B.3
  • 5
    • 84875803407 scopus 로고    scopus 로고
    • Obese schizophrenia spectrum patients have significantly higher 10-year general cardiovascular risk and vascular ages than obese individuals without severe mental illness
    • Ratliff JC, Palmese LB, Reutenauer EL, Srihari VH, Tek C. Obese schizophrenia spectrum patients have significantly higher 10-year general cardiovascular risk and vascular ages than obese individuals without severe mental illness. Psychosomatics 2013; 54: 67-73.
    • (2013) Psychosomatics , vol.54 , pp. 67-73
    • Ratliff, J.C.1    Palmese, L.B.2    Reutenauer, E.L.3    Srihari, V.H.4    Tek, C.5
  • 6
    • 84962975894 scopus 로고
    • A study of malnutrition in chronic schizophrenia
    • Baganz CN, Norris JM. A study of malnutrition in chronic schizophrenia. Am J Psychiatry 1943; 99: 534-541.
    • (1943) Am J Psychiatry , vol.99 , pp. 534-541
    • Baganz, C.N.1    Norris, J.M.2
  • 7
    • 77955051243 scopus 로고    scopus 로고
    • Low prevalence of obesity and metabolic syndrome in never-treated chronic schizophrenia
    • Padmavati R, McCreadie RG, Tirupati S. Low prevalence of obesity and metabolic syndrome in never-treated chronic schizophrenia. Schizophr Res 2010; 121: 199-202.
    • (2010) Schizophr Res , vol.121 , pp. 199-202
    • Padmavati, R.1    McCreadie, R.G.2    Tirupati, S.3
  • 8
    • 84876531583 scopus 로고    scopus 로고
    • A behavioral weight-loss intervention in persons with serious mental illness
    • Daumit GL, Dickerson FB, Wang NY etal. A behavioral weight-loss intervention in persons with serious mental illness. N Engl J Med 2013; 368: 1594-1602.
    • (2013) N Engl J Med , vol.368 , pp. 1594-1602
    • Daumit, G.L.1    Dickerson, F.B.2    Wang, N.Y.3
  • 9
    • 34848885102 scopus 로고    scopus 로고
    • A pilot study of a weight management program with food provision in schizophrenia
    • Jean-Baptiste M, Tek C, Liskov E etal. A pilot study of a weight management program with food provision in schizophrenia. Schizophr Res 2007; 96: 198-205.
    • (2007) Schizophr Res , vol.96 , pp. 198-205
    • Jean-Baptiste, M.1    Tek, C.2    Liskov, E.3
  • 10
    • 84871859439 scopus 로고    scopus 로고
    • Contingency management for the treatment of antipsychotic-induced weight gain: a randomized controlled pilot study
    • Ratliff JC, Palmese LB, Tonizzo KM, Chwastiak L, Tek C. Contingency management for the treatment of antipsychotic-induced weight gain: a randomized controlled pilot study. Obes Facts 2012; 5: 919-927.
    • (2012) Obes Facts , vol.5 , pp. 919-927
    • Ratliff, J.C.1    Palmese, L.B.2    Tonizzo, K.M.3    Chwastiak, L.4    Tek, C.5
  • 11
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Knowler WC, Barrett-Connor E, Fowler SE etal. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 12
    • 33748961798 scopus 로고    scopus 로고
    • Attenuation of antipsychotic-induced weight gain with early behavioral intervention in drug-naive first-episode psychosis patients: a randomized controlled trial
    • Alvarez-Jimenez M, Gonzalez-Blanch C, Vazquez-Barquero JL etal. Attenuation of antipsychotic-induced weight gain with early behavioral intervention in drug-naive first-episode psychosis patients: a randomized controlled trial. J Clin Psychiatry 2006; 67: 1253-1260.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1253-1260
    • Alvarez-Jimenez, M.1    Gonzalez-Blanch, C.2    Vazquez-Barquero, J.L.3
  • 13
    • 84901724640 scopus 로고    scopus 로고
    • An exploratory randomized controlled study of a healthy living intervention in early intervention services for psychosis: the INTERvention to encourage ACTivity, improve diet, and reduce weight gain (INTERACT) study
    • Lovell K, Wearden A, Bradshaw T etal. An exploratory randomized controlled study of a healthy living intervention in early intervention services for psychosis: the INTERvention to encourage ACTivity, improve diet, and reduce weight gain (INTERACT) study. J Clin Psychiatry 2014; 75: 498-505.
    • (2014) J Clin Psychiatry , vol.75 , pp. 498-505
    • Lovell, K.1    Wearden, A.2    Bradshaw, T.3
  • 14
    • 0032751075 scopus 로고    scopus 로고
    • Antipsychotic-induced weight gain: a comprehensive research synthesis
    • Allison DB, Mentore JL, Heo M etal. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry 1999; 156: 1686-1696.
    • (1999) Am J Psychiatry , vol.156 , pp. 1686-1696
    • Allison, D.B.1    Mentore, J.L.2    Heo, M.3
  • 15
    • 72149090641 scopus 로고    scopus 로고
    • Metabolic side effects of antipsychotic drug treatment-pharmacological mechanisms
    • Reynolds GP, Kirk SL. Metabolic side effects of antipsychotic drug treatment-pharmacological mechanisms. Pharmacol Ther 2010; 125: 169-179.
    • (2010) Pharmacol Ther , vol.125 , pp. 169-179
    • Reynolds, G.P.1    Kirk, S.L.2
  • 16
    • 73649134285 scopus 로고    scopus 로고
    • The role of histaminergic H1 and H3 receptors in food intake: a mechanism for atypical antipsychotic-induced weight gain?
    • Deng C, Weston-Green K, Huang X-F. The role of histaminergic H1 and H3 receptors in food intake: a mechanism for atypical antipsychotic-induced weight gain? Prog Neuropsychopharmacol Biol Psychiatry 2010; 34: 1-4.
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , pp. 1-4
    • Deng, C.1    Weston-Green, K.2    Huang, X.-F.3
  • 17
    • 84879316703 scopus 로고    scopus 로고
    • The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain
    • He M, Deng C, Huang XF. The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain. CNS Drugs 2013; 27: 423-434.
    • (2013) CNS Drugs , vol.27 , pp. 423-434
    • He, M.1    Deng, C.2    Huang, X.F.3
  • 18
    • 78649950286 scopus 로고    scopus 로고
    • Association of prescription H1 antihistamine use with obesity: results from the National Health and Nutrition Examination Survey
    • Ratliff JC, Barber JA, Palmese LB, Reutenauer EL, Tek C. Association of prescription H1 antihistamine use with obesity: results from the National Health and Nutrition Examination Survey. Obesity (Silver Spring) 2010; 18: 2398-2400.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 2398-2400
    • Ratliff, J.C.1    Barber, J.A.2    Palmese, L.B.3    Reutenauer, E.L.4    Tek, C.5
  • 19
    • 25144456112 scopus 로고    scopus 로고
    • Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
    • Lieberman JA, Stroup TS, McEvoy JP etal. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 2005; 353: 1209-1223.
    • (2005) N Engl J Med , vol.353 , pp. 1209-1223
    • Lieberman, J.A.1    Stroup, T.S.2    McEvoy, J.P.3
  • 20
    • 39149089276 scopus 로고    scopus 로고
    • Weight gain induced by haloperidol, risperidone and olanzapine after 1 year: findings of a randomized clinical trial in a drug-naive population
    • Perez-Iglesias R, Crespo-Facorro B, Martinez-Garcia O etal. Weight gain induced by haloperidol, risperidone and olanzapine after 1 year: findings of a randomized clinical trial in a drug-naive population. Schizophr Res 2008; 99: 13-22.
    • (2008) Schizophr Res , vol.99 , pp. 13-22
    • Perez-Iglesias, R.1    Crespo-Facorro, B.2    Martinez-Garcia, O.3
  • 21
    • 84899729584 scopus 로고    scopus 로고
    • Almost all antipsychotics result in weight gain: a meta-analysis
    • Bak M, Fransen A, Janssen J, van Os J, Drukker M. Almost all antipsychotics result in weight gain: a meta-analysis. PLoS ONE 2014; 9: e94112, 1-19.
    • (2014) PLoS ONE , vol.9 , pp. 1-19
    • Bak, M.1    Fransen, A.2    Janssen, J.3    van Os, J.4    Drukker, M.5
  • 23
    • 0142011201 scopus 로고    scopus 로고
    • Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome
    • Woods SW, Breier A, Zipursky RB etal. Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome. Biol Psychiatry 2003; 54: 453-464.
    • (2003) Biol Psychiatry , vol.54 , pp. 453-464
    • Woods, S.W.1    Breier, A.2    Zipursky, R.B.3
  • 24
    • 34249331312 scopus 로고    scopus 로고
    • Weight gain in newly diagnosed first-episode psychosis patients and healthy comparisons: one-year analysis
    • Strassnig M, Miewald J, Keshavan M, Ganguli R. Weight gain in newly diagnosed first-episode psychosis patients and healthy comparisons: one-year analysis. Schizophr Res 2007; 93: 90-98.
    • (2007) Schizophr Res , vol.93 , pp. 90-98
    • Strassnig, M.1    Miewald, J.2    Keshavan, M.3    Ganguli, R.4
  • 25
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009; 339: b2535.
    • (2009) BMJ , vol.339 , pp. b2535
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4    Group, P.5
  • 26
    • 84884161208 scopus 로고    scopus 로고
    • Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis
    • Leucht S, Cipriani A, Spineli L etal. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet 2013; 382: 951-962.
    • (2013) Lancet , vol.382 , pp. 951-962
    • Leucht, S.1    Cipriani, A.2    Spineli, L.3
  • 28
    • 30944462144 scopus 로고    scopus 로고
    • Meta-analysis of heterogeneously reported trials assessing change from baseline
    • Abrams KR, Gillies CL, Lambert PC. Meta-analysis of heterogeneously reported trials assessing change from baseline. Stat Med 2005; 24: 3823-3844.
    • (2005) Stat Med , vol.24 , pp. 3823-3844
    • Abrams, K.R.1    Gillies, C.L.2    Lambert, P.C.3
  • 29
    • 85047695195 scopus 로고    scopus 로고
    • Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis
    • McGlashan TH, Zipursky RB, Perkins D etal. Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. Am J Psychiatry 2006; 163: 790-799.
    • (2006) Am J Psychiatry , vol.163 , pp. 790-799
    • McGlashan, T.H.1    Zipursky, R.B.2    Perkins, D.3
  • 30
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 31
    • 84877996294 scopus 로고    scopus 로고
    • Metabolic risk factors in first-episode schizophrenia: baseline prevalence and course analysed from the European First-Episode Schizophrenia Trial
    • Fleischhacker WW, Siu CO, Boden R, Pappadopulos E, Karayal ON, Kahn RS. Metabolic risk factors in first-episode schizophrenia: baseline prevalence and course analysed from the European First-Episode Schizophrenia Trial. Int J Neuropsychopharmacol 2013; 16: 987-995.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 987-995
    • Fleischhacker, W.W.1    Siu, C.O.2    Boden, R.3    Pappadopulos, E.4    Karayal, O.N.5    Kahn, R.S.6
  • 32
    • 79952169014 scopus 로고    scopus 로고
    • Ziprasidone vs. olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial
    • Grootens KP, van Veelen NM, Peuskens J etal. Ziprasidone vs. olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial. Schizophr Bull 2011; 37: 352-361.
    • (2011) Schizophr Bull , vol.37 , pp. 352-361
    • Grootens, K.P.1    van Veelen, N.M.2    Peuskens, J.3
  • 33
    • 67349136738 scopus 로고    scopus 로고
    • Metabolic profiles of second-generation antipsychotics in early psychosis: findings from the CAFE study
    • Patel JK, Buckley PF, Woolson S etal. Metabolic profiles of second-generation antipsychotics in early psychosis: findings from the CAFE study. Schizophr Res 2009; 111: 9-16.
    • (2009) Schizophr Res , vol.111 , pp. 9-16
    • Patel, J.K.1    Buckley, P.F.2    Woolson, S.3
  • 34
    • 21044457943 scopus 로고    scopus 로고
    • Risperidone and haloperidol in first-episode psychosis: a long-term randomized trial
    • Schooler N, Rabinowitz J, Davidson M etal. Risperidone and haloperidol in first-episode psychosis: a long-term randomized trial. Am J Psychiatry 2005; 162: 947-953.
    • (2005) Am J Psychiatry , vol.162 , pp. 947-953
    • Schooler, N.1    Rabinowitz, J.2    Davidson, M.3
  • 35
    • 28644433423 scopus 로고    scopus 로고
    • Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol
    • Zipursky RB, Gu H, Green AI etal. Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol. Br J Psychiatry 2005; 187: 537-543.
    • (2005) Br J Psychiatry , vol.187 , pp. 537-543
    • Zipursky, R.B.1    Gu, H.2    Green, A.I.3
  • 36
    • 0037712923 scopus 로고    scopus 로고
    • Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52-week randomized trial of clozapine vs. chlorpromazine
    • Lieberman JA, Phillips M, Gu H etal. Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52-week randomized trial of clozapine vs. chlorpromazine. Neuropsychopharmacology 2003; 28: 995-1003.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 995-1003
    • Lieberman, J.A.1    Phillips, M.2    Gu, H.3
  • 37
    • 75649152091 scopus 로고    scopus 로고
    • Early intervention with second-generation antipsychotics in first-episode psychosis: results of an 8-week naturalistic study
    • Josiassen RC, Shaughnessy RA, Filymer DM etal. Early intervention with second-generation antipsychotics in first-episode psychosis: results of an 8-week naturalistic study. Early Interv Psychiatry 2010; 4: 57-63.
    • (2010) Early Interv Psychiatry , vol.4 , pp. 57-63
    • Josiassen, R.C.1    Shaughnessy, R.A.2    Filymer, D.M.3
  • 38
    • 1642406111 scopus 로고    scopus 로고
    • A trial of low doses of risperidone in the treatment of patients with first-episode schizophrenia, schizophreniform disorder, or schizoaffective disorder
    • Huq ZU. A trial of low doses of risperidone in the treatment of patients with first-episode schizophrenia, schizophreniform disorder, or schizoaffective disorder. J Clin Psychopharmacol 2004; 24: 220-224.
    • (2004) J Clin Psychopharmacol , vol.24 , pp. 220-224
    • Huq, Z.U.1
  • 39
    • 75649144370 scopus 로고    scopus 로고
    • Trial of aripiprazole in the treatment of first-episode schizophrenia
    • Lee HY, Ham BJ, Kang RH etal. Trial of aripiprazole in the treatment of first-episode schizophrenia. Psychiatry Clin Neurosci 2010; 64: 38-43.
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 38-43
    • Lee, H.Y.1    Ham, B.J.2    Kang, R.H.3
  • 40
    • 84924997621 scopus 로고    scopus 로고
    • Very low-dose risperidone in first-episode psychosis: a safe and effective way to initiate treatment
    • McGorry PD, Cocks J, Power P, Burnett P, Harrigan S, Lambert T. Very low-dose risperidone in first-episode psychosis: a safe and effective way to initiate treatment. Schizophr Res Treatment 2011; 2011: 631690.
    • (2011) Schizophr Res Treatment , vol.2011 , pp. 631690
    • McGorry, P.D.1    Cocks, J.2    Power, P.3    Burnett, P.4    Harrigan, S.5    Lambert, T.6
  • 41
    • 84873729944 scopus 로고    scopus 로고
    • Comparison of metabolic effects of ziprasidone versus olanzapine treatment in patients with first-episode schizophrenia
    • Ou JJ, Xu Y, Chen HH etal. Comparison of metabolic effects of ziprasidone versus olanzapine treatment in patients with first-episode schizophrenia. Psychopharmacology (Berl) 2013; 225: 627-635.
    • (2013) Psychopharmacology (Berl) , vol.225 , pp. 627-635
    • Ou, J.J.1    Xu, Y.2    Chen, H.H.3
  • 42
    • 27744568397 scopus 로고    scopus 로고
    • Weight gain and lipid metabolic abnormalities induced by olanzapine in first-episode, drug-naive patients with psychotic disorders
    • Sengupta SM, Klink R, Stip E, Baptista T, Malla A, Joober R. Weight gain and lipid metabolic abnormalities induced by olanzapine in first-episode, drug-naive patients with psychotic disorders. Schizophr Res 2005; 80: 131-133.
    • (2005) Schizophr Res , vol.80 , pp. 131-133
    • Sengupta, S.M.1    Klink, R.2    Stip, E.3    Baptista, T.4    Malla, A.5    Joober, R.6
  • 43
    • 67651148120 scopus 로고    scopus 로고
    • Efficacy and tolerability of aripiprazole in first-episode drug naive patients with schizophrenia: an open-label trial
    • Takahashi H, Oshimo T, Ishigooka J. Efficacy and tolerability of aripiprazole in first-episode drug naive patients with schizophrenia: an open-label trial. Clin Neuropharmacol 2009; 32: 149-150.
    • (2009) Clin Neuropharmacol , vol.32 , pp. 149-150
    • Takahashi, H.1    Oshimo, T.2    Ishigooka, J.3
  • 44
    • 0036855229 scopus 로고    scopus 로고
    • Quetiapine: an effective antipsychotic in first-episode schizophrenia despite only transiently high dopamine-2 receptor blockade
    • Tauscher-Wisniewski S, Kapur S, Tauscher J etal. Quetiapine: an effective antipsychotic in first-episode schizophrenia despite only transiently high dopamine-2 receptor blockade. J Clin Psychiatry 2002; 63: 992-997.
    • (2002) J Clin Psychiatry , vol.63 , pp. 992-997
    • Tauscher-Wisniewski, S.1    Kapur, S.2    Tauscher, J.3
  • 45
    • 0034950896 scopus 로고    scopus 로고
    • Risperidone in the treatment of first episode psychosis
    • Yap HL, Mahendran R, Lim D etal. Risperidone in the treatment of first episode psychosis. Singapore Med J 2001; 42: 170-173.
    • (2001) Singapore Med J , vol.42 , pp. 170-173
    • Yap, H.L.1    Mahendran, R.2    Lim, D.3
  • 46
    • 0142025520 scopus 로고    scopus 로고
    • Effectiveness, safety, and tolerability of risperidone in adolescents with schizophrenia: an open-label study
    • Zalsman G, Carmon E, Martin A, Bensason D, Weizman A, Tyano S. Effectiveness, safety, and tolerability of risperidone in adolescents with schizophrenia: an open-label study. J Child Adolesc Psychopharmacol 2003; 13: 319-327.
    • (2003) J Child Adolesc Psychopharmacol , vol.13 , pp. 319-327
    • Zalsman, G.1    Carmon, E.2    Martin, A.3    Bensason, D.4    Weizman, A.5    Tyano, S.6
  • 47
    • 84862804429 scopus 로고    scopus 로고
    • Efficacy and safety of ziprasidone in the treatment of first-episode psychosis: an 8-week, open-label, multicenter trial
    • Zhao T, Park TW, Yang JC etal. Efficacy and safety of ziprasidone in the treatment of first-episode psychosis: an 8-week, open-label, multicenter trial. Int Clin Psychopharmacol 2012; 27: 184-190.
    • (2012) Int Clin Psychopharmacol , vol.27 , pp. 184-190
    • Zhao, T.1    Park, T.W.2    Yang, J.C.3
  • 48
    • 84881242882 scopus 로고    scopus 로고
    • Randomized trial of clozapine vs. risperidone in treatment-naive first-episode schizophrenia: results after one year
    • Sanz-Fuentenebro J, Taboada D, Palomo T etal. Randomized trial of clozapine vs. risperidone in treatment-naive first-episode schizophrenia: results after one year. Schizophr Res 2013; 149: 156-161.
    • (2013) Schizophr Res , vol.149 , pp. 156-161
    • Sanz-Fuentenebro, J.1    Taboada, D.2    Palomo, T.3
  • 49
    • 21244486283 scopus 로고    scopus 로고
    • Pharmacological treatment and other predictors of treatment outcomes in previously untreated patients with schizophrenia: results from the European Schizophrenia Outpatient Health Outcomes (SOHO) study
    • Gasquet I, Haro JM, Novick D, Edgell ET, Kennedy L, Lepine JP. Pharmacological treatment and other predictors of treatment outcomes in previously untreated patients with schizophrenia: results from the European Schizophrenia Outpatient Health Outcomes (SOHO) study. Int Clin Psychopharmacol 2005; 20: 199-205.
    • (2005) Int Clin Psychopharmacol , vol.20 , pp. 199-205
    • Gasquet, I.1    Haro, J.M.2    Novick, D.3    Edgell, E.T.4    Kennedy, L.5    Lepine, J.P.6
  • 50
    • 79952609670 scopus 로고    scopus 로고
    • Effect of risperidone on metabolic parameters in antipsychotic-naïve schizophrenia: a prospective one year follow-up study
    • Vinay HR, Sundar GSK, Behere RV etal. Effect of risperidone on metabolic parameters in antipsychotic-naïve schizophrenia: a prospective one year follow-up study. Asian J Psychiatr 2011; 4: 73-74.
    • (2011) Asian J Psychiatr , vol.4 , pp. 73-74
    • Vinay, H.R.1    Sundar, G.S.K.2    Behere, R.V.3
  • 51
    • 70349405933 scopus 로고    scopus 로고
    • Comparison of effects of olanzapine and risperidone on body mass index and blood sugar level in schizophrenic patients
    • Ingole S, Belorkar NR, Waradkar P, Shrivastava M. Comparison of effects of olanzapine and risperidone on body mass index and blood sugar level in schizophrenic patients. Indian J Physiol Pharmacol 2009; 53: 47-54.
    • (2009) Indian J Physiol Pharmacol , vol.53 , pp. 47-54
    • Ingole, S.1    Belorkar, N.R.2    Waradkar, P.3    Shrivastava, M.4
  • 52
    • 77949507803 scopus 로고    scopus 로고
    • Olanzapine orally disintegrating tablets (Zyprexa Zydis) rapidly improve excitement components in the acute phase of first-episode schizophrenic patients: an open-label prospective study
    • Hori H, Ueda N, Yoshimura R etal. Olanzapine orally disintegrating tablets (Zyprexa Zydis) rapidly improve excitement components in the acute phase of first-episode schizophrenic patients: an open-label prospective study. World J Biol Psychiatry 2009; 10: 741-745.
    • (2009) World J Biol Psychiatry , vol.10 , pp. 741-745
    • Hori, H.1    Ueda, N.2    Yoshimura, R.3
  • 53
    • 84908042980 scopus 로고    scopus 로고
    • Comparison of metabolic effects of aripiprazole, quetiapine and ziprasidone after 12 weeks of treatment in first treated episode of psychosis
    • Perez-Iglesias R, Ortiz-Garcia de la Foz V, Martinez Garcia O etal. Comparison of metabolic effects of aripiprazole, quetiapine and ziprasidone after 12 weeks of treatment in first treated episode of psychosis. Schizophr Res 2014; 159: 90-94.
    • (2014) Schizophr Res , vol.159 , pp. 90-94
    • Perez-Iglesias, R.1    Ortiz-Garcia de la Foz, V.2    Martinez Garcia, O.3
  • 54
    • 84916208120 scopus 로고    scopus 로고
    • Long-term efficacy and safety of blonanserin in patients with first-episode schizophrenia: a 1-year open-label trial
    • Ninomiya Y, Miyamoto S, Tenjin T etal. Long-term efficacy and safety of blonanserin in patients with first-episode schizophrenia: a 1-year open-label trial. Psychiatry Clin Neurosci 2014; 68: 841-849.
    • (2014) Psychiatry Clin Neurosci , vol.68 , pp. 841-849
    • Ninomiya, Y.1    Miyamoto, S.2    Tenjin, T.3
  • 55
    • 84930477713 scopus 로고    scopus 로고
    • Randomized controlled trial comparing changes in serum prolactin and weight among female patients with first-episode schizophrenia over 12 months of treatment with risperidone or quetiapine
    • Liu J, Sun J, Shen X etal. Randomized controlled trial comparing changes in serum prolactin and weight among female patients with first-episode schizophrenia over 12 months of treatment with risperidone or quetiapine. Shanghai Arch Psychiatry 2014; 26: 88-94.
    • (2014) Shanghai Arch Psychiatry , vol.26 , pp. 88-94
    • Liu, J.1    Sun, J.2    Shen, X.3
  • 56
    • 84929942280 scopus 로고    scopus 로고
    • Neocortical serotonin2A receptor binding predicts quetiapine associated weight gain in antipsychotic-naive first-episode schizophrenia patients
    • Rasmussen H, Ebdrup BH, Oranje B, Pinborg LH, Knudsen GM, Glenthoj B. Neocortical serotonin2A receptor binding predicts quetiapine associated weight gain in antipsychotic-naive first-episode schizophrenia patients. Int J Neuropsychopharmacol 2014; 17: 1729-1736.
    • (2014) Int J Neuropsychopharmacol , vol.17 , pp. 1729-1736
    • Rasmussen, H.1    Ebdrup, B.H.2    Oranje, B.3    Pinborg, L.H.4    Knudsen, G.M.5    Glenthoj, B.6
  • 57
    • 0033136622 scopus 로고    scopus 로고
    • Ziprasidone 80mg/day and 160mg/day in the acute exacerbation of schizophrenia and schizoaffective disorder: a 6-week placebo-controlled trial. Ziprasidone Study Group
    • Daniel DG, Zimbroff DL, Potkin SG, Reeves KR, Harrigan EP, Lakshminarayanan M. Ziprasidone 80mg/day and 160mg/day in the acute exacerbation of schizophrenia and schizoaffective disorder: a 6-week placebo-controlled trial. Ziprasidone Study Group. Neuropsychopharmacology 1999; 20: 491-505.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 491-505
    • Daniel, D.G.1    Zimbroff, D.L.2    Potkin, S.G.3    Reeves, K.R.4    Harrigan, E.P.5    Lakshminarayanan, M.6
  • 58
    • 84962978289 scopus 로고    scopus 로고
    • Updated 2014 January, 2014; cited 8 August 2014]
    • Pfizer I. Goedon Prescribing Information, 2014 [Updated 2014 January, 2014; cited 8 August 2014.] Available from URL: http://labeling.pfizer.com/ShowLabeling.aspx?id=584
    • (2014) Goedon Prescribing Information
    • Pfizer, I.1
  • 59
    • 30444450710 scopus 로고    scopus 로고
    • Distinct functional profiles of aripiprazole and olanzapine at RNA edited human 5-HT2C receptor isoforms
    • Zhang JY, Kowal DM, Nawoschik SP, Lou Z, Dunlop J. Distinct functional profiles of aripiprazole and olanzapine at RNA edited human 5-HT2C receptor isoforms. Biochem Pharmacol 2006; 71: 521-529.
    • (2006) Biochem Pharmacol , vol.71 , pp. 521-529
    • Zhang, J.Y.1    Kowal, D.M.2    Nawoschik, S.P.3    Lou, Z.4    Dunlop, J.5
  • 60
    • 80052490081 scopus 로고    scopus 로고
    • A randomized trial examining the effectiveness of switching from olanzapine, quetiapine, or risperidone to aripiprazole to reduce metabolic risk: comparison of antipsychotics for metabolic problems (CAMP)
    • Stroup TS, McEvoy JP, Ring KD etal. A randomized trial examining the effectiveness of switching from olanzapine, quetiapine, or risperidone to aripiprazole to reduce metabolic risk: comparison of antipsychotics for metabolic problems (CAMP). Am J Psychiatry 2011; 168: 947-956.
    • (2011) Am J Psychiatry , vol.168 , pp. 947-956
    • Stroup, T.S.1    McEvoy, J.P.2    Ring, K.D.3
  • 61
    • 44949155699 scopus 로고    scopus 로고
    • Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders: a systematic critical reappraisal
    • Álvarez-Jiménez M, González-Blanch C, Crespo-Facorro B etal. Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders: a systematic critical reappraisal. CNS Drugs 2008; 22: 547-563.
    • (2008) CNS Drugs , vol.22 , pp. 547-563
    • Álvarez-Jiménez, M.1    González-Blanch, C.2    Crespo-Facorro, B.3
  • 62
    • 85012092311 scopus 로고    scopus 로고
    • Early intervention in psychosis. The critical period hypothesis
    • Birchwood M, Todd P, Jackson C. Early intervention in psychosis. The critical period hypothesis. Br J Psychiatry Suppl 1998; 172: 53-59.
    • (1998) Br J Psychiatry Suppl , vol.172 , pp. 53-59
    • Birchwood, M.1    Todd, P.2    Jackson, C.3


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