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Volumn 10, Issue 5, 2015, Pages

Systematic review: Representativeness of participants in RCTs of acetylcholinesterase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE INHIBITOR; DONEPEZIL; GALANTAMINE; MEMANTINE; PSYCHOTROPIC AGENT; RIVASTIGMINE;

EID: 84929192411     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124500     Document Type: Review
Times cited : (41)

References (63)
  • 2
    • 84869437442 scopus 로고    scopus 로고
    • Drug policy for an aging population-the european medicines agency's geriatric medicines strategy
    • PMID: 23171092
    • Cerreta F, Eichler H, Rasi G. Drug policy for an aging population-the european medicines agency's geriatric medicines strategy. N Engl J Med. 2012; 367: 1972-1974. doi: 10.1056/NEJMp1209034 PMID: 23171092
    • (2012) N Engl J Med , vol.367 , pp. 1972-1974
    • Cerreta, F.1    Eichler, H.2    Rasi, G.3
  • 3
    • 0027404728 scopus 로고
    • Reporting of age data in clinical trials of arthritis. Deficiencies and solutions
    • PMID: 8422212
    • Rochon PA, Fortin PR, Dear KB, Minaker KL, Chalmers TC. Reporting of age data in clinical trials of arthritis. Deficiencies and solutions. Arch Intern Med. 1993; 153: 243-248. PMID: 8422212
    • (1993) Arch Intern Med , vol.153 , pp. 243-248
    • Rochon, P.A.1    Fortin, P.R.2    Dear, K.B.3    Minaker, K.L.4    Chalmers, T.C.5
  • 4
    • 0033619959 scopus 로고    scopus 로고
    • Underrepresentation of patients 65 years of age or older in cancer-treatment trials
    • PMID: 10615079
    • Hutchins LF, Unger JM, Crowley JJ, Coltman CA Jr, Albain KS. Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med. 1999; 341: 2061-2067. PMID: 10615079
    • (1999) N Engl J Med , vol.341 , pp. 2061-2067
    • Hutchins, L.F.1    Unger, J.M.2    Crowley, J.J.3    Coltman, C.A.4    Albain, K.S.5
  • 5
    • 0038662715 scopus 로고    scopus 로고
    • Participation of patients 65 years of age or older in cancer clinical trials
    • PMID: 12663731
    • Lewis JH, Kilgore ML, Goldman DP, Trimble EL, Kaplan R, Montello MJ, et al. Participation of patients 65 years of age or older in cancer clinical trials. J Clin Oncol. 2003; 21: 1383-1389. PMID: 12663731
    • (2003) J Clin Oncol , vol.21 , pp. 1383-1389
    • Lewis, J.H.1    Kilgore, M.L.2    Goldman, D.P.3    Trimble, E.L.4    Kaplan, R.5    Montello, M.J.6
  • 6
    • 0035827865 scopus 로고    scopus 로고
    • Representation of elderly persons and women in published randomized trials of acute coronary syndromes
    • PMID: 11495621
    • Lee PY, Alexander KP, Hammill BG, Pasquali SK, Peterson ED. Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA. 2001; 286: 708-713. PMID: 11495621
    • (2001) JAMA , vol.286 , pp. 708-713
    • Lee, P.Y.1    Alexander, K.P.2    Hammill, B.G.3    Pasquali, S.K.4    Peterson, E.D.5
  • 7
    • 0037067884 scopus 로고    scopus 로고
    • Representation of the elderly, women, and minorities in heart failure clinical trials
    • PMID: 12153370
    • Heiat A, Gross CP, Krumholz HM. Representation of the elderly, women, and minorities in heart failure clinical trials. Arch Intern Med. 2002; 162: 1682-1688. PMID: 12153370
    • (2002) Arch Intern Med , vol.162 , pp. 1682-1688
    • Heiat, A.1    Gross, C.P.2    Krumholz, H.M.3
  • 8
    • 15544362080 scopus 로고    scopus 로고
    • Clinical trials of potential antidepressants: To what extent are the elderly represented: A review
    • PMID: 15717338
    • Giron MS, Fastbom J, Winblad B. Clinical trials of potential antidepressants: To what extent are the elderly represented: A review. Int J Geriatr Psychiatry. 2005; 20: 201-217. PMID: 15717338
    • (2005) Int J Geriatr Psychiatry , vol.20 , pp. 201-217
    • Giron, M.S.1    Fastbom, J.2    Winblad, B.3
  • 9
    • 19444366654 scopus 로고    scopus 로고
    • Systematic review of barriers to the recruitment of older patients with cancer onto clinical trials
    • PMID: 15860871
    • Townsley CA, Selby R, Siu LL. Systematic review of barriers to the recruitment of older patients with cancer onto clinical trials. J Clin Oncol. 2005; 23: 3112-3124. PMID: 15860871
    • (2005) J Clin Oncol , vol.23 , pp. 3112-3124
    • Townsley, C.A.1    Selby, R.2    Siu, L.L.3
  • 10
    • 0042991391 scopus 로고    scopus 로고
    • Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure
    • PMID: 12891192
    • Masoudi FA, Havranek EP, Wolfe P, Gross CP, Rathore SS, Steiner JF, et al. Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure. Am Heart J. 2003; 146: 250-257. PMID: 12891192
    • (2003) Am Heart J , vol.146 , pp. 250-257
    • Masoudi, F.A.1    Havranek, E.P.2    Wolfe, P.3    Gross, C.P.4    Rathore, S.S.5    Steiner, J.F.6
  • 11
    • 84929190103 scopus 로고    scopus 로고
    • 27 May Available: Accessed 21 February 2014
    • EFGCP Geriatric Medicines Working Party. EFGCP guidelines on medical research for and with older people in Europe. 27 May 2013. Available: https://www.kcl.ac.uk/sspp/departments/sshm/news/EFGCP-GMWP-Research-Guidelines-Final-edited-2013-05-27.pdf. Accessed 21 February 2014.
    • (2013) EFGCP Guidelines on Medical Research for and With Older People in Europe
  • 12
    • 77956325385 scopus 로고    scopus 로고
    • Fighting against age discrimination in clinical trials
    • PMID: 20863340
    • Cherubini A, Del Signore S, Ouslander J, Semla T, Michel JP. Fighting against age discrimination in clinical trials. J Am Geriatr Soc. 2010; 58: 1791-1796. doi: 10.1111/j.1532-5415.2010.03032.x PMID: 20863340
    • (2010) J Am Geriatr Soc , vol.58 , pp. 1791-1796
    • Cherubini, A.1    Del Signore, S.2    Ouslander, J.3    Semla, T.4    Michel, J.P.5
  • 13
    • 84903313687 scopus 로고
    • 24 Jun Available: Accessed 07 March 2014
    • International conference on harmonization (ICH) expert working group. ICH harmonized tripartite guideline. Studies in support of special populations: geriatrics E7. 24 Jun 1993. Available: http://www.ich.org/fileadmin/Public-Web-Site/ICH-Products/Guidelines/Efficacy/E7/Step4/E7-Guideline.pdf. Accessed 07 March 2014.
    • (1993) ICH Harmonized Tripartite Guideline. Studies in Support of Special Populations: Geriatrics E7
  • 14
    • 84857104091 scopus 로고    scopus 로고
    • 17 Feb Available: Accessed 23 January 2014
    • European Medicines Agency. EMA geriatric medicines strategy. 17 Feb 2011. Available: http://www.ema.europa.eu/docs/en-GB/document-library/Other/2011/02/WC500102291.pdf. Accessed 23 January 2014.
    • (2011) EMA Geriatric Medicines Strategy
  • 16
    • 68049122102 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • PMID: 19621072
    • Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. 2009 PLoS Med 6: e1000097. doi: 10.1371/journal.pmed.1000097 PMID: 19621072
    • (2009) PLoS Med , vol.6 , pp. e1000097
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 17
    • 0016823810 scopus 로고
    • 'Mini mental state'. A practical method for grading the cognitive state of patients for the clinician
    • PMID: 1202204
    • Folstein MF, Folstein SE, McHugh PR. 'Mini mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12: 189-198. PMID: 1202204
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 18
    • 84902141749 scopus 로고    scopus 로고
    • Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - The medication use among persons with Alzheimer's disease (MEDALZ-2005) study
    • PMID: 23950660
    • Tolppanen AM, Taipale H, Koponen M, Lavikainen P, Tanskanen A, Tiihonen J, et al. Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - the medication use among persons with Alzheimer's disease (MEDALZ-2005) study. Clin Epidemiol. 2013; 5: 277-285. doi: 10.2147/CLEP.S46622 PMID: 23950660
    • (2013) Clin Epidemiol , vol.5 , pp. 277-285
    • Tolppanen, A.M.1    Taipale, H.2    Koponen, M.3    Lavikainen, P.4    Tanskanen, A.5    Tiihonen, J.6
  • 19
    • 79952111664 scopus 로고    scopus 로고
    • Update on current care guidelines. The diagnosis and medical treatment of memory disorders
    • PMID: 21072963
    • Suhonen J, Pirttila T, Erkinjuntti T, Koponen H, Makkonen M, Puurunen M, et al. Update on current care guidelines. The diagnosis and medical treatment of memory disorders. Duodecim 2010; 126: 2167-2168. PMID: 21072963
    • (2010) Duodecim , vol.126 , pp. 2167-2168
    • Suhonen, J.1    Pirttila, T.2    Erkinjuntti, T.3    Koponen, H.4    Makkonen, M.5    Puurunen, M.6
  • 21
    • 0021271971 scopus 로고
    • Clinical diagnosis of alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease
    • PMID: 6610841
    • McKhann G, Drachman D, Folstein M. Clinical diagnosis of alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology. 1984; 34: 939-944. PMID: 6610841
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 23
    • 0001618597 scopus 로고
    • Estimating the mean and variance of normal populations from singly and doubly truncated samples
    • Cohen AC. Estimating the mean and variance of normal populations from singly and doubly truncated samples. Ann Math Statist. 1950; 21: 557-569.
    • (1950) Ann Math Statist , vol.21 , pp. 557-569
    • Cohen, A.C.1
  • 24
    • 10244259208 scopus 로고    scopus 로고
    • The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial
    • PMID: 8915035
    • Rogers S, Friedhoff LT. The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia. 1996; 7: 293-303. PMID: 8915035
    • (1996) Dementia , vol.7 , pp. 293-303
    • Rogers, S.1    Friedhoff, L.T.2
  • 25
    • 0029917179 scopus 로고    scopus 로고
    • Safety/tolerability trial of SDZ ENA 713 in patients with probable alzheimer's disease
    • PMID: 8614273
    • Sramek JJ, Anand R, Wardle TS, Irwin P, Hartman RD, Cutler NR. Safety/tolerability trial of SDZ ENA 713 in patients with probable alzheimer's disease. Life Sci. 1996; 58: 1201-1207. PMID: 8614273
    • (1996) Life Sci , vol.58 , pp. 1201-1207
    • Sramek, J.J.1    Anand, R.2    Wardle, T.S.3    Irwin, P.4    Hartman, R.D.5    Cutler, N.R.6
  • 27
    • 0031902795 scopus 로고    scopus 로고
    • A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease
    • Corey-Bloom J, Anand R, Veach J. A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998; 1: 55-65.
    • (1998) Int J Geriatr Psychopharmacol , vol.1 , pp. 55-65
    • Corey-Bloom, J.1    Anand, R.2    Veach, J.3
  • 28
    • 0032507788 scopus 로고    scopus 로고
    • Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study
    • PMID: 9588436
    • Rogers SL, Doody RS, Mohs RC, Friedhoff LT; the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Arch Intern Med. 1998; 158: 1021-1031. PMID: 9588436
    • (1998) Arch Intern Med , vol.158 , pp. 1021-1031
    • Rogers, S.L.1    Doody, R.S.2    Mohs, R.C.3    Friedhoff, L.T.4
  • 29
    • 0031883716 scopus 로고    scopus 로고
    • A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
    • PMID: 9443470
    • Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology. 1998; 50: 136-145. PMID: 9443470
    • (1998) Neurology , vol.50 , pp. 136-145
    • Rogers, S.L.1    Farlow, M.R.2    Doody, R.S.3    Mohs, R.4    Friedhoff, L.T.5
  • 30
    • 0032926540 scopus 로고    scopus 로고
    • The effects of donepezil in Alzheimer's disease - Results from a multinational trial
    • PMID: 10325453
    • Burns A, Rossor M, Hecker J, Gauthier S, Petit H, Möller HJ, et al. The effects of donepezil in Alzheimer's disease - results from a multinational trial. Dement Geriatr Cogn Disord. 1999; 10: 237-244. PMID: 10325453
    • (1999) Dement Geriatr Cogn Disord , vol.10 , pp. 237-244
    • Burns, A.1    Rossor, M.2    Hecker, J.3    Gauthier, S.4    Petit, H.5    Möller, H.J.6
  • 31
    • 0032814386 scopus 로고    scopus 로고
    • A phase II study in patients with Alzheimer's disease to assess the preliminary efficacy and maximum tolerated dose of rivastigmine (Exelon)
    • PMID: 10362894
    • Forette F, Anand R, Gharabawi G. A phase II study in patients with Alzheimer's disease to assess the preliminary efficacy and maximum tolerated dose of rivastigmine (Exelon). Eur J Neurol. 1999; 6: 423-429. PMID: 10362894
    • (1999) Eur J Neurol , vol.6 , pp. 423-429
    • Forette, F.1    Anand, R.2    Gharabawi, G.3
  • 32
    • 0033528436 scopus 로고    scopus 로고
    • Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial
    • Rösler M, Anand R, Cicin-Sain A, Gauthier S, Agid Y, Dal-Bianco P, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. Br Med J. 1999; 318: 633-640.
    • (1999) Br Med J , vol.318 , pp. 633-640
    • Rösler, M.1    Anand, R.2    Cicin-Sain, A.3    Gauthier, S.4    Agid, Y.5    Dal-Bianco, P.6
  • 34
    • 0033758977 scopus 로고    scopus 로고
    • Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan
    • PMID: 11044775
    • Homma A, Takeda M, Imai Y, Udaka F, Hasegawa K, Kameyama M, et al. Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan. Dement Geriatr Cogn Disord. 2000; 11: 299-313. PMID: 11044775
    • (2000) Dement Geriatr Cogn Disord , vol.11 , pp. 299-313
    • Homma, A.1    Takeda, M.2    Imai, Y.3    Udaka, F.4    Hasegawa, K.5    Kameyama, M.6
  • 35
    • 0034720816 scopus 로고    scopus 로고
    • Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension
    • PMID: 10881250
    • Raskind MA, Peskind ER, Wessel T, Yuan W, Allen FH, Aronson SM, et al. Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. Neurology. 2000; 54: 2261-2268. PMID: 10881250
    • (2000) Neurology , vol.54 , pp. 2261-2268
    • Raskind, M.A.1    Peskind, E.R.2    Wessel, T.3    Yuan, W.4    Allen, F.H.5    Aronson, S.M.6
  • 36
    • 0034720864 scopus 로고    scopus 로고
    • A 5-month, randomized, placebo-controlled trial of galantamine in AD
    • PMID: 10881251
    • Tariot PN, Solomon PR, Morris JC, Kershaw P, Lilienfeld S, Ding C, et al. A 5-month, randomized, placebo-controlled trial of galantamine in AD. Neurology. 2000; 54: 2269-2276. PMID: 10881251
    • (2000) Neurology , vol.54 , pp. 2269-2276
    • Tariot, P.N.1    Solomon, P.R.2    Morris, J.C.3    Kershaw, P.4    Lilienfeld, S.5    Ding, C.6
  • 37
    • 0034627263 scopus 로고    scopus 로고
    • Efficacy and safety of galantamine in patients with mild to moderate Alzheimer's disease: Multicentre randomised controlled trial
    • PMID: 11110737
    • Wilcock GK, Lilienfeld S, Gaens E. Efficacy and safety of galantamine in patients with mild to moderate Alzheimer's disease: Multicentre randomised controlled trial. BMJ. 2000; 321: 1445-1449. PMID: 11110737
    • (2000) BMJ , vol.321 , pp. 1445-1449
    • Wilcock, G.K.1    Lilienfeld, S.2    Gaens, E.3
  • 38
    • 0035964226 scopus 로고    scopus 로고
    • A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease
    • PMID: 11524468
    • Feldman H, Gauthier S, Hecker J, Vellas B, Subbiah P, Whalen E, et al. A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease. Neurology. 2001; 57: 613-620. PMID: 11524468
    • (2001) Neurology , vol.57 , pp. 613-620
    • Feldman, H.1    Gauthier, S.2    Hecker, J.3    Vellas, B.4    Subbiah, P.5    Whalen, E.6
  • 39
    • 0035859851 scopus 로고    scopus 로고
    • A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients
    • PMID: 11502917
    • Mohs RC, Doody RS, Morris JC, Ieni JR, Rogers SL, Perdomo CA, et al. A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients. Neurology. 2001; 57: 481-488. PMID: 11502917
    • (2001) Neurology , vol.57 , pp. 481-488
    • Mohs, R.C.1    Doody, R.S.2    Morris, J.C.3    Ieni, J.R.4    Rogers, S.L.5    Perdomo, C.A.6
  • 40
    • 0034771057 scopus 로고    scopus 로고
    • Effects of a flexible galantamine dose in Alzheimer's disease: A randomised, controlled trial
    • PMID: 11606667
    • Rockwood K, Mintzer J, Truyen L, Wessel T, Wilkinson D. Effects of a flexible galantamine dose in Alzheimer's disease: A randomised, controlled trial. J Neurol Neurosurg Psychiatry. 2001; 71: 589-595. PMID: 11606667
    • (2001) J Neurol Neurosurg Psychiatry , vol.71 , pp. 589-595
    • Rockwood, K.1    Mintzer, J.2    Truyen, L.3    Wessel, T.4    Wilkinson, D.5
  • 41
    • 0034810025 scopus 로고    scopus 로고
    • Galantamine: A randomized, double-blind, dose comparison in patients with Alzheimer's disease
    • PMID: 11571763
    • Wilkinson D, Murray J. Galantamine: A randomized, double-blind, dose comparison in patients with Alzheimer's disease. Int J Geriatr Psychiatry. 2001; 16: 852-857. PMID: 11571763
    • (2001) Int J Geriatr Psychiatry , vol.16 , pp. 852-857
    • Wilkinson, D.1    Murray, J.2
  • 42
    • 0035859879 scopus 로고    scopus 로고
    • A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD
    • PMID: 11502918
    • Winblad B, Engedal K, Soininen H, Verhey F, Waldemar G, Wimo A, et al. A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD. Neurology. 2001; 57: 489-495. PMID: 11502918
    • (2001) Neurology , vol.57 , pp. 489-495
    • Winblad, B.1    Engedal, K.2    Soininen, H.3    Verhey, F.4    Waldemar, G.5    Wimo, A.6
  • 43
    • 1842830710 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease
    • PMID: 14594748
    • Krishnan KR, Charles HC, Doraiswamy PM, Mintzer J, Weisler R, Yu X, et al. Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease. Am J Psychiatry. 2003; 160: 2003-2011. PMID: 14594748
    • (2003) Am J Psychiatry , vol.160 , pp. 2003-2011
    • Krishnan, K.R.1    Charles, H.C.2    Doraiswamy, P.M.3    Mintzer, J.4    Weisler, R.5    Yu, X.6
  • 44
    • 84885838681 scopus 로고    scopus 로고
    • Efficacy of rivastigmine in patients with severe Alzheimer's disease: A double-blind, randomized pilot study
    • Lopez-Pousa S, Vilalta-Franch J, Hernandez B, Rapatz G. Efficacy of rivastigmine in patients with severe Alzheimer's disease: A double-blind, randomized pilot study. Brain Aging. 2004; 4: 26-34.
    • (2004) Brain Aging , vol.4 , pp. 26-34
    • Lopez-Pousa, S.1    Vilalta-Franch, J.2    Hernandez, B.3    Rapatz, G.4
  • 45
    • 10044228581 scopus 로고    scopus 로고
    • Efficacy of donepezil in early-stage Alzheimer disease: A randomized placebo-controlled trial
    • PMID: 15596605
    • Seltzer B, Zolnouni P, Nunez M, Goldman R, Kumar D, Ieni J, et al. Efficacy of donepezil in early-stage Alzheimer disease: A randomized placebo-controlled trial. Arch Neurol. 2004; 61: 1852-1856. PMID: 15596605
    • (2004) Arch Neurol , vol.61 , pp. 1852-1856
    • Seltzer, B.1    Zolnouni, P.2    Nunez, M.3    Goldman, R.4    Kumar, D.5    Ieni, J.6
  • 47
    • 10844273072 scopus 로고    scopus 로고
    • A 12-month study of the efficacy of rivastigmine in patients with advanced moderate Alzheimer's disease
    • PMID: 15383747
    • Karaman Y, Erdogan F, Koseoglu E, Turan T, Ersoy AO. A 12-month study of the efficacy of rivastigmine in patients with advanced moderate Alzheimer's disease. Dement Geriatr Cogn Disord. 2005; 19: 51-56. PMID: 15383747
    • (2005) Dement Geriatr Cogn Disord , vol.19 , pp. 51-56
    • Karaman, Y.1    Erdogan, F.2    Koseoglu, E.3    Turan, T.4    Ersoy, A.O.5
  • 48
    • 33645906519 scopus 로고    scopus 로고
    • Attainment of treatment goals by people with Alzheimer's disease receiving galantamine: A randomized controlled trial
    • PMID: 16554498
    • Rockwood K, Fay S, Song X, MacKnight C, Gorman M; the Video-Imaging Synthesis of Treating Alzheimer's Disease (VISTA) Investigators. Attainment of treatment goals by people with Alzheimer's disease receiving galantamine: A randomized controlled trial. CMAJ. 2006; 174: 1099-1105. PMID: 16554498
    • (2006) CMAJ , vol.174 , pp. 1099-1105
    • Rockwood, K.1    Fay, S.2    Song, X.3    MacKnight, C.4    Gorman, M.5
  • 49
    • 34548081204 scopus 로고    scopus 로고
    • Donepezil preserves cognition and global function in patients with severe Alzheimer disease
    • PMID: 17664405
    • Black SE, Doody R, Li H, McRae T, Jambor KM, Xu Y, et al. Donepezil preserves cognition and global function in patients with severe Alzheimer disease. Neurology. 2007; 69: 459-469. PMID: 17664405
    • (2007) Neurology , vol.69 , pp. 459-469
    • Black, S.E.1    Doody, R.2    Li, H.3    McRae, T.4    Jambor, K.M.5    Xu, Y.6
  • 50
    • 34547639795 scopus 로고    scopus 로고
    • Rivastigmine: A placebo controlled trial of twice daily and three times daily regimens in patients with Alzheimer's disease
    • PMID: 17353259
    • Feldman HH, Lane R. Rivastigmine: A placebo controlled trial of twice daily and three times daily regimens in patients with Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2007; 78: 1056-1063. PMID: 17353259
    • (2007) J Neurol Neurosurg Psychiatry , vol.78 , pp. 1056-1063
    • Feldman, H.H.1    Lane, R.2
  • 51
    • 34249683625 scopus 로고    scopus 로고
    • A six-month doubleblind, randomized, placebo-controlled study of a transdermal patch in Alzheimer's disease - Rivastigmine patch versus capsule
    • PMID: 17380489
    • Winblad B, Cummings J, Andreasen N, Grossberg G, Onofrj M, Sadowsky C, et al. A six-month doubleblind, randomized, placebo-controlled study of a transdermal patch in Alzheimer's disease - rivastigmine patch versus capsule. Int J Geriatr Psychiatry. 2007; 22: 456-467. PMID: 17380489
    • (2007) Int J Geriatr Psychiatry , vol.22 , pp. 456-467
    • Winblad, B.1    Cummings, J.2    Andreasen, N.3    Grossberg, G.4    Onofrj, M.5    Sadowsky, C.6
  • 52
    • 43049134839 scopus 로고    scopus 로고
    • Donepezil treatment of patients with severe Alzheimer's disease in a Japanese population: Results from a 24-week, double-blind, placebo-controlled, randomized trial
    • PMID: 18391486
    • Homma A, Imai Y, Tago H, Asada T, Shigeta M, Iwamoto T, et al. Donepezil treatment of patients with severe Alzheimer's disease in a Japanese population: Results from a 24-week, double-blind, placebo-controlled, randomized trial. Dement Geriatr Cogn Disord. 2008; 25: 399-407. doi: 10.1159/000122961 PMID: 18391486
    • (2008) Dement Geriatr Cogn Disord , vol.25 , pp. 399-407
    • Homma, A.1    Imai, Y.2    Tago, H.3    Asada, T.4    Shigeta, M.5    Iwamoto, T.6
  • 53
    • 84863272674 scopus 로고    scopus 로고
    • A 24-week, randomized, doubleblind, placebo-controlled study to evaluate the efficacy, safety and tolerability of the rivastigmine patch in Japanese patients with Alzheimer's disease
    • PMID: 22163242
    • Nakamura Y, Imai Y, Shigeta M, Graf A, Shirahase T, Kim H, et al. A 24-week, randomized, doubleblind, placebo-controlled study to evaluate the efficacy, safety and tolerability of the rivastigmine patch in Japanese patients with Alzheimer's disease. Dement Geriatr Cogn Dis Extra. 2011; 1: 163-179. doi: 10.1159/000328929 PMID: 22163242
    • (2011) Dement Geriatr Cogn Dis Extra , vol.1 , pp. 163-179
    • Nakamura, Y.1    Imai, Y.2    Shigeta, M.3    Graf, A.4    Shirahase, T.5    Kim, H.6
  • 54
    • 84896696643 scopus 로고    scopus 로고
    • Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer's disease
    • PMID: 24591834
    • Hager K, Baseman AS, Nye JS, Brashear HR, Han J, Sano M, et al. Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer's disease. Neuropsychiatr Dis Treat. 2014; 10: 391-401. doi: 10.2147/NDT.S57909 PMID: 24591834
    • (2014) Neuropsychiatr Dis Treat , vol.10 , pp. 391-401
    • Hager, K.1    Baseman, A.S.2    Nye, J.S.3    Brashear, H.R.4    Han, J.5    Sano, M.6
  • 55
    • 4544274539 scopus 로고    scopus 로고
    • The age gap between patients in clinical studies and in the general population: A pitfall for dementia research
    • PMID: 15380160
    • Schoenmaker N, Van Gool WA. The age gap between patients in clinical studies and in the general population: A pitfall for dementia research. Lancet Neurol. 2004; 3: 627-630. PMID: 15380160
    • (2004) Lancet Neurol , vol.3 , pp. 627-630
    • Schoenmaker, N.1    Van Gool, W.A.2
  • 57
    • 84859117778 scopus 로고    scopus 로고
    • Underrepresentation of elderly people in randomised controlled trials. The example of trials of 4 widely prescribed drugs
    • Konrat C, Boutron I, Trinquart L, Auleley GR, Ricordeau P, Ravaud P. Underrepresentation of elderly people in randomised controlled trials. The example of trials of 4 widely prescribed drugs. PLoS One. 2012; doi: 10.1371/journal.pone.0033559
    • (2012) PLoS One
    • Konrat, C.1    Boutron, I.2    Trinquart, L.3    Auleley, G.R.4    Ricordeau, P.5    Ravaud, P.6
  • 58
    • 79961217664 scopus 로고    scopus 로고
    • Exclusion of older people from clinical trials: Professional views from nine European countries participating in the PREDICT study
    • PMID: 21812501
    • Crome P, Lally F, Cherubini A, Oristrell J, Beswick AD, Clarfield AM, et al. Exclusion of older people from clinical trials: Professional views from nine European countries participating in the PREDICT study. Drugs Aging. 2011; 28: 667-677. doi: 10.2165/11591990-000000000-00000 PMID: 21812501
    • (2011) Drugs Aging , vol.28 , pp. 667-677
    • Crome, P.1    Lally, F.2    Cherubini, A.3    Oristrell, J.4    Beswick, A.D.5    Clarfield, A.M.6
  • 59
    • 4444258303 scopus 로고    scopus 로고
    • Research consent for cognitively impaired adults: Recommendations for institutional review boards and investigators
    • PMID: 15494623
    • Alzheimer's Association. Research consent for cognitively impaired adults: Recommendations for institutional review boards and investigators. Alzheimer Dis Assoc Disord. 2004; 18: 171-175. PMID: 15494623
    • (2004) Alzheimer Dis Assoc Disord , vol.18 , pp. 171-175
    • Alzheimer's Association1
  • 60
    • 79952553710 scopus 로고    scopus 로고
    • Exclusion of older adults and women from recent trials of acute coronary syndromes
    • PMID: 21361882
    • Dodd KS, Saczynski JS, Zhao Y, Goldberg RJ, Gurwitz JH. Exclusion of older adults and women from recent trials of acute coronary syndromes. J Am Geriatr Soc. 2011; 59: 506-511. doi: 10.1111/j.1532-5415.2010.03305.x PMID: 21361882
    • (2011) J Am Geriatr Soc , vol.59 , pp. 506-511
    • Dodd, K.S.1    Saczynski, J.S.2    Zhao, Y.3    Goldberg, R.J.4    Gurwitz, J.H.5
  • 61
    • 0030793014 scopus 로고    scopus 로고
    • Eligibility of Alzheimer's disease clinic patients for clinical trials
    • PMID: 9256842
    • Schneider LS, Olin JT, Lyness SA, Chui HC. Eligibility of Alzheimer's disease clinic patients for clinical trials. J Am Geriatr Soc. 1997; 45: 923-928. PMID: 9256842
    • (1997) J Am Geriatr Soc , vol.45 , pp. 923-928
    • Schneider, L.S.1    Olin, J.T.2    Lyness, S.A.3    Chui, H.C.4
  • 63
    • 84911991732 scopus 로고    scopus 로고
    • The French National Alzheimer Database: A Fast Growing Database for Researchers and Clinicians
    • PMID: 24994018
    • Anthony S, Pradier C, Chevrier R, Festraëts J, Tifratene K, Robert P, et al. The French National Alzheimer Database: A Fast Growing Database for Researchers and Clinicians. Dement Geriatr Cogn Disord. 2014; 38: 271-280. doi: 10.1159/000360281 PMID: 24994018
    • (2014) Dement Geriatr Cogn Disord , vol.38 , pp. 271-280
    • Anthony, S.1    Pradier, C.2    Chevrier, R.3    Festraëts, J.4    Tifratene, K.5    Robert, P.6


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