Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model?

BMC Anesthesiology

Volumn 15, Issue 1, 2015, Pages

  Bendel, Stepani S ^a,b   Springe, Dirk D ^a   Pereira, Adriano A ^a   Grandgirard, Denis D ^a   Leib, Stephen S L ^a,c   Putzu, Alessandro A ^a   Schlickeiser, Jannis J ^a   Jakob, Stephan S M ^a   Takala, Jukka J ^a   Haenggi, Matthias M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c SPIEZ LABORATORY   (Switzerland)

Author keywords

Cardiac arrest; Fentanyl; Ketamine; Medetomidine; Neuroprotection; Rats; Sevoflurane

Indexed keywords

ANESTHETIC AGENT; FENTANYL; INTERLEUKIN 6; KETAMINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MEDETOMIDINE; MONOCYTE CHEMOTACTIC PROTEIN 1; SEVOFLURANE; TUMOR NECROSIS FACTOR ALPHA; ETHER DERIVATIVE;

ANESTHESIA; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATELECTASIS; BRAIN DAMAGE; BRAIN HISTOLOGY; CEREBROSPINAL FLUID; CONTROLLED STUDY; HEART ARREST; HIPPOCAMPUS; HYPOTENSION; INFLAMMATION; MALE; METABOLIC ALKALOSIS; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NONHUMAN; OVERALL SURVIVAL; RAT; RESPIRATORY ACIDOSIS; RESPIRATORY ALKALOSIS; ANIMAL; DRUG EFFECTS; NERVOUS SYSTEM DISEASES; PATHOPHYSIOLOGY; WISTAR RAT;

ANESTHETICS; ANIMALS; APOPTOSIS; FENTANYL; HEART ARREST; HIPPOCAMPUS; KETAMINE; MALE; MEDETOMIDINE; METHYL ETHERS; NERVOUS SYSTEM DISEASES; RATS, WISTAR;

EID: 84929167768     PISSN: None     EISSN: 14712253     Source Type: Journal    
DOI: 10.1186/1471-2253-15-2     Document Type: Article

References (37)

1. Madl C, Holzer M: Brain function after resuscitation from cardiac arrest. Curr Opin Crit Care 2004,10(3):213-7. 10.1097/01.ccx.0000127542.32890.fa
2. Hossmann KA: Cerebral ischemia: models, methods and outcomes. Neuropharmacology 2008,55(3):257-70. 10.1016/j.neuropharm.2007.12.004
3. Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, et al.: Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002,346(8):557-63. 10.1056/NEJMoa003289
4. TherapeuticHypothermiaGroup: Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002,346(8):549-56.
5. Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Gasche Y, Hassager C, et al.: Targeted temperature management at 33 degrees C versus 36 degrees C after cardiac arrest. N Engl J Med 2013,369(23):2197-206. 10.1056/NEJMoa1310519
6. von Planta I, Weil MH, von Planta M, Bisera J, Bruno S, Gazmuri RJ, et al.: Cardiopulmonary resuscitation in the rat. J Appl Physiol 1988,65(6):2641-7.
7. Bottiger BW, Krumnikl JJ, Gass P, Schmitz B, Motsch J, Martin E: The cerebral 'no-reflow' phenomenon after cardiac arrest in rats-influence of low-flow reperfusion. Resuscitation 1997,34(1):79-87. 10.1016/S0300-9572(96)01029-5
8. Hendrickx HH, Rao GR, Safar P, Gisvold SE: Asphyxia, cardiac arrest and resuscitation in rats. I. Short term recovery. Resuscitation 1984,12(2):97-116. 10.1016/0300-9572(84)90062-5
9. Rogers P, Hillman H: Biochemical changes in the blood during hypothermic cardiac arrest and recovery of rats. Resuscitation 1972,1(1):25-9. 10.1016/0300-9572(72)90060-3
10. Blomqvist P, Wieloch T: Ischemic brain damage in rats following cardiac arrest using a long-term recovery model. J Cereb Blood Flow Metab 1985,5(3):420-31. 10.1038/jcbfm.1985.57
11. Head BP, Patel P: Anesthetics and brain protection. Curr Opin Anaesthesiol 2007,20(5):395-9. 10.1097/ACO.0b013e3282efa69d
12. Haenggi M: Anesthesia and analgesia protocol during therapeutic hypothermia after cardiac arrest: it is time to build evidence. Anesth Analg 2010,110(5):1259-60. 10.1213/ANE.0b013e3181d77357
13. Hellstrom J, Owall A, Martling CR, Sackey PV: Inhaled isoflurane sedation during therapeutic hypothermia after cardiac arrest: a case series. Crit Care Med 2014,42(2):e161-6. 10.1097/CCM.0b013e3182a643d7
14. Katz L, Ebmeyer U, Safar P, Radovsky A, Neumar R: Outcome model of asphyxial cardiac arrest in rats. J Cereb Blood Flow Metab 1995,15(6):1032-9. 10.1038/jcbfm.1995.129
15. Manwani B, Liu F, Xu Y, Persky R, Li J, McCullough LD: Functional recovery in aging mice after experimental stroke. Brain Behav Immun 2011,25(8):1689-700. 10.1016/j.bbi.2011.06.015
16. Albertsmeier M, Teschendorf P, Popp E, Galmbacher R, Vogel P, Bottiger BW: Evaluation of a tape removal test to assess neurological deficit after cardiac arrest in rats. Resuscitation 2007,74(3):552-8. 10.1016/j.resuscitation.2007.01.040
17. Walsh RN, Cummins RA: The open-field test: a critical review. Psychol Bull 1976,83(3):482-504.
18. Grandgirard D, Oberson K, Buhlmann A, Gaumann R, Leib SL: Attenuation of cerebrospinal fluid inflammation by the nonbacteriolytic antibiotic daptomycin versus that by ceftriaxone in experimental pneumococcal meningitis. Antimicrob Agents Chemother 2010,54(3):1323-6. 10.1128/AAC.00812-09
19. Schmidt-Kastner R, Freund TF: Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 1991,40(3):599-636. 10.1016/0306-4522(91)90001-5
20. Adamczyk S, Robin E, Simerabet M, Kipnis E, Tavernier B, Vallet B, et al.: Sevoflurane pre- and post-conditioning protect the brain via the mitochondrial K ATP channel. Br J Anaesth 2010,104(2):191-200. 10.1093/bja/aep365
21. Zhu J, Jiang X, Shi E, Ma H, Wang J: Sevoflurane preconditioning reverses impairment of hippocampal long-term potentiation induced by myocardial ischaemia-reperfusion injury. Eur J Anaesthesiol 2009,26(11):961-8. 10.1097/EJA.0b013e328330e968
22. Landoni G, Greco T, Biondi-Zoccai G, Nigro Neto C, Febres D, Pintaudi M, et al.: Anaesthetic drugs and survival: a Bayesian network meta-analysis of randomized trials in cardiac surgery. Br J Anaesth 2013,111(6):886-96. 10.1093/bja/aet231
23. Meybohm P, Gruenewald M, Albrecht M, Zacharowski KD, Lucius R, Zitta K, et al.: Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling. PLoS One 2009,4(10):e7588. 10.1371/journal.pone.0007588
24. Zitta K, Meybohm P, Bein B, Ohnesorge H, Steinfath M, Scholz J, et al.: Cytoprotective effects of the volatile anesthetic sevoflurane are highly dependent on timing and duration of sevoflurane conditioning: findings from a human, in-vitro hypoxia model. Eur J Pharmacol 2010,645(1-3):39-46.
25. Maier C, Steinberg GK, Sun GH, Zhi GT, Maze M: Neuroprotection by the alpha 2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia. Anesthesiology 1993,79(2):306-12. 10.1097/00000542-199308000-00016
26. Jolkkonen J, Puurunen K, Koistinaho J, Kauppinen R, Haapalinna A, Nieminen L, et al.: Neuroprotection by the alpha2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia. Eur J Pharmacol 1999,372(1):31-6. 10.1016/S0014-2999(99)00186-7
27. Hudetz JA, Pagel PS: Neuroprotection by ketamine: a review of the experimental and clinical evidence. J Cardiothorac Vasc Anesth 2010,24(1):131-42. 10.1053/j.jvca.2009.05.008
28. Teschendorf P, Padosch SA, Spohr F, Albertsmeier M, Schneider A, Vogel P, et al.: Time course of caspase activation in selectively vulnerable brain areas following global cerebral ischemia due to cardiac arrest in rats. Neurosci Lett 2008,448(2):194-9. 10.1016/j.neulet.2008.10.030
29. Knapp J, Bergmann G, Bruckner T, Russ N, Bottiger BW, Popp E: Pre- and postconditioning effect of Sevoflurane on myocardial dysfunction after cardiopulmonary resuscitation in rats. Resuscitation 2013,84(10):1450-5. 10.1016/j.resuscitation.2013.04.012
30. Ivacko J, Szaflarski J, Malinak C, Flory C, Warren JS, Silverstein FS: Hypoxic-ischemic injury induces monocyte chemoattractant protein-1 expression in neonatal rat brain. J Cereb Blood Flow Metab 1997,17(7):759-70.
31. Liu H, Sarnaik SM, Manole MD, Chen Y, Shinde SN, Li W, et al.: Increased cytochrome c in rat cerebrospinal fluid after cardiac arrest and its effects on hypoxic neuronal survival. Resuscitation 2012,83(12):1491-6. 10.1016/j.resuscitation.2012.04.009
32. Rosen C, Rosen H, Andreasson U, Bremell D, Bremler R, Hagberg L, et al.: Cerebrospinal fluid biomarkers in cardiac arrest survivors. Resuscitation 2014,85(2):227-32. 10.1016/j.resuscitation.2013.10.032
33. Langdon KD, Granter-Button S, Corbett D: Persistent behavioral impairments and neuroinflammation following global ischemia in the rat. Eur J Neurosci 2008,28(11):2310-8. 10.1111/j.1460-9568.2008.06513.x
34. Hsu WH, Hummel SK: Xylazine-induced hyperglycemia in cattle: a possible involvement of alpha 2-adrenergic receptors regulating insulin release. Endocrinology 1981,109(3):825-9. 10.1210/endo-109-3-825
35. Nurmi J, Boyd J, Anttalainen N, Westerbacka J, Kuisma M: Early increase in blood glucose in patients resuscitated from out-of-hospital ventricular fibrillation predicts poor outcome. Diabetes Care 2012,35(3):510-2. 10.2337/dc11-1478
36. Becker DE, Rosenberg M: Nitrous oxide and the inhalation anesthetics. Anesth Prog 2008,55(4):124-30. quiz 131-122 10.2344/0003-3006-55.4.124
37. Kiryk A, Pluta R, Figiel I, Mikosz M, Ulamek M, Niewiadomska G, et al.: Transient brain ischemia due to cardiac arrest causes irreversible long-lasting cognitive injury. Behav Brain Res 2011,219(1):1-7. 10.1016/j.bbr.2010.12.004