Frailty and mortality in dialysis: Evaluation of a clinical frailty scale

Clinical Journal of the American Society of Nephrology

Volumn 10, Issue 5, 2015, Pages 832-840

  Alfaadhel, Talal A ^a   Soroka, Steven D ^a   Kiberd, Bryce A ^a   Landry, David ^a   Moorhouse, Paige ^a   Tennankore, Karthik K ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ASSESSMENT OF HUMANS; CHARLSON COMORBIDITY INDEX; CLINICAL FRAILTY SCALE; COHORT ANALYSIS; CONTROLLED STUDY; DEATH; DIABETIC NEPHROPATHY; DIALYSIS; END STAGE RENAL DISEASE; FEMALE; FOLLOW UP; FRAILTY; GLOMERULUS FILTRATION RATE; HUMAN; INCIDENCE; KIDNEY ALLOGRAFT; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PHYSICAL DISEASE BY BODY FUNCTION; AGED; COMPLICATION; FRAIL ELDERLY; GERIATRIC ASSESSMENT; HEALTH STATUS INDICATOR; HEMODIALYSIS; KIDNEY FAILURE, CHRONIC; MIDDLE AGED; PROCEDURES; PROPORTIONAL HAZARDS MODEL; SURVIVAL RATE; TIME FACTOR;

AGED; DIABETIC NEPHROPATHIES; FEMALE; FRAIL ELDERLY; GERIATRIC ASSESSMENT; HEALTH STATUS INDICATORS; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RENAL DIALYSIS; SURVIVAL RATE; TIME FACTORS;

EID: 84929157892     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.07760814     Document Type: Article

References (39)

1. Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, Mitnitski A: A global clinical measure of fitness and frailty in elderly people. CMAJ 173: 489–495, 2005
2. Bao Y, Dalrymple L, Chertow GM, Kaysen GA, Johansen KL: Frailty, dialysis initiation, and mortality in end-stage renal disease. Arch Intern Med 172: 1071–1077, 2012
3. Johansen KL, Chertow GM, Jin C, Kutner NG: Significance of frailty among dialysis patients. J Am Soc Nephrol 18: 2960–2967, 2007
4. McAdams-DeMarco MA, Law A, Salter ML, Boyarsky B, Gimenez L, Jaar BG, Walston JD, Segev DL: Frailty as a novel predictor of mortality and hospitalization in individuals of all ages undergoing hemodialysis. J Am Geriatr Soc 61: 896–901, 2013
5. McAdams-DeMarco MA, Suresh S, Law A, Salter ML, Gimenez LF, Jaar BG, Walston JD, Segev DL: Frailty and falls among adult patients undergoing chronic hemodialysis: A prospective cohort study. BMC Nephrol 14: 224, 2013
6. Conroy S, Dowsing T: The ability of frailty to predict outcomes in older people attending an acute medical unit. AcuteMed 12: 74–76, 2013
7. Ekerstad N, Swahn E, Janzon M, Alfredsson J, Löfmark R, Lindenberger M, Carlsson P: Frailty is independently associated with short-term outcomes for elderly patientswith non-ST-segment elevation myocardial infarction. Circulation 124: 2397–2404, 2011
8. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA; Cardiovascular Health Study Collaborative Research Group: Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56: M146–M156, 2001
9. Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis 40: 373–383, 1987
10. Fried L, Bernardini J, Piraino B: Charlson comorbidity index as a predictor of outcomes in incident peritoneal dialysis patients. Am J Kidney Dis 37: 337–342, 2001
11. Di Iorio B, Cillo N, Cirillo M, De Santo NG: Charlson Comorbidity Index is a predictor of outcomes in incident hemodialysis patients and correlates with phase angle and hospitalization. Int J Artif Organs 27: 330–336, 2004
12. Villar E, Remontet L, Labeeuw M, Ecochard R: Effect of age, gender, and diabetes on excess death in end-stage renal failure. J Am Soc Nephrol 18: 2125–2134, 2007
13. Bleyer AJ, Tell GS, Evans GW, Ettinger WH Jr., Burkart JM: Survival of patients undergoing renal replacement therapy in one center with special emphasis on racial differences. Am J Kidney Dis 28: 72–81, 1996
14. Pei YP, Greenwood CM, Chery AL, Wu GG: Racial differences in survival of patients on dialysis. Kidney Int 58: 1293–1299, 2000
15. Wong JS, Port FK, Hulbert-Shearon TE, Carroll CE, Wolfe RA, Agodoa LY, Daugirdas JT: Survival advantage in Asian American end-stage renal disease patients. Kidney Int 55: 2515–2523, 1999
16. Mailloux LU, Bellucci AG, Mossey RT, Napolitano B, Moore T, Wilkes BM, Bluestone PA: Predictors of survival in patients undergoing dialysis. Am J Med 84: 855–862, 1988
17. Molnar MZ, Streja E, Kovesdy CP, Bunnapradist S, Sampaio MS, Jing J, Krishnan M, Nissenson AR, Danovitch GM, Kalantar- Zadeh K: Associations of body mass index and weight loss with mortality in transplant-waitlisted maintenance hemodialysis patients. Am J Transplant 11: 725–736, 2011
18. Beddhu S, Samore MH, Roberts MS, Stoddard GJ, Ramkumar N, Pappas LM, Cheung AK: Impact of timing of initiation of dialysis on mortality. J Am Soc Nephrol 14: 2305–2312, 2003
19. Owen WF Jr., Lew NL, Liu Y, Lowrie EG, Lazarus JM: The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. NEngl J Med 329: 1001–1006, 1993
20. Fenton SS, Schaubel DE, Desmeules M, Morrison HI, Mao Y, Copleston P, Jeffery JR, Kjellstrand CM: Hemodialysis versus peritoneal dialysis: A comparison of adjustedmortality rates. Am J Kidney Dis 30: 334–342, 1997
21. Ganesh SK, Hulbert-Shearon T, Port FK, Eagle K, Stack AG: Mortality differences by dialysis modality among incident ESRD patients with and without coronary artery disease. J Am Soc Nephrol 14: 415–424, 2003
22. Foley RN, Parfrey PS, Sarnak MJ: Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol 9[Suppl]: S16–S23, 1998
23. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296–1305, 2004
24. Zoccali C, Tripepi G, Mallamaci F: Predictors of cardiovascular death in ESRD. Semin Nephrol 25: 358–362, 2005
25. Kuro-o M: A potential link between phosphate and aging— lessons from Klotho-deficient mice. Mech Ageing Dev 131: 270–275, 2010
26. Stenvinkel P, Larsson TE: Chronic kidney disease: A clinical model of premature aging. Am J Kidney Dis 62: 339–351, 2013
27. Rockwood K, Mogilner A, Mitnitski A: Changes with age in the distribution of a frailty index. Mech Ageing Dev 125: 517–519, 2004
28. Painter P, Kuskowski M: A closer look at frailty in ESRD: Getting the measure right. Hemodial Int 17: 41–49, 2013
29. Mallery LH, Allen M, Fleming I, Kelly K, Bowles S, Duncan J, Moorhouse P: Promoting higher blood pressure targets for frail older adults: A consensus guideline from Canada. Cleve Clin J Med 81: 427–437, 2014
30. Bergman H, Ferrucci L, Guralnik J, Hogan DB, Hummel S, Karunananthan S, Wolfson C: Frailty: An emerging research and clinical paradigm—issues and controversies. J Gerontol A Biol Sci Med Sci 62: 731–737, 2007
31. Bouillon K, Kivimaki M, Hamer M, Sabia S, Fransson EI, Singh- Manoux A, Gale CR, BattyGD: Measures of frailty in populationbased studies: An overview. BMC Geriatr 13: 64, 2013
32. Rothman MD, Leo-Summers L, Gill TM: Prognostic significance of potential frailty criteria. J AmGeriatr Soc 56: 2211–2216, 2008
33. Moorhouse P, Mallery LH: Palliative and therapeutic harmonization: A model for appropriate decision-making in frail older adults. J Am Geriatr Soc 60: 2326–2332, 2012
34. Renal Physicians Association: Shared Decision-Making in the Appropriate Initiation of and Withdrawal from Dialysis, 2nd Ed., Rockville, MD, Renal Physicians Association, 2010
35. Bagshaw SM, Stelfox HT, McDermid RC, Rolfson DB, Tsuyuki RT, Baig N, Artiuch B, Ibrahim Q, Stollery DE, Rokosh E, Majumdar SR: Association between frailty and short- and long-term outcomes among critically ill patients: A multicentre prospective cohort study. CMAJ 186: E95–E102, 2014
36. Chan DC, Tsou HH, Chen CY, Chen CY: Validation of the Chinese-Canadian study of health and aging clinical frailty scale (CSHA-CFS) telephone version. Arch Gerontol Geriatr 50: e74–e80, 2010
37. Murray AM, Tupper DE, Knopman DS, Gilbertson DT, Pederson SL, Li S, Smith GE, Hochhalter AK, Collins AJ, Kane RL: Cognitive impairment in hemodialysis patients is common. Neurology 67: 216–223, 2006
38. Sehgal AR, Grey SF, DeOreo PB, Whitehouse PJ: Prevalence, recognition, and implications of mental impairment among hemodialysis patients. Am J Kidney Dis 30: 41–49, 1997
39. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D; Modification of Diet in Renal Disease Study Group: A more accurate method to estimate glomerular filtration rate fromserum creatinine: A new prediction equation. Ann Intern Med 130: 461–470, 1999