Increased visit-to-visit blood pressure variability is associated with worse cardiovascular outcomes in low ejection fraction heart failure patients: Insights from the HEAAL study

International Journal of Cardiology

Volumn 187, Issue 1, 2015, Pages 183-189

  Rossignol, P ^a,b,c,d,e   Girerd, N ^a,b,c,d,e   Gregory, D ^f   Massarog, J ^g   Konstam, M A ^h   Zannada, F ^a,b,c,d,e  

^a INSERM   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c INSERM UMR S 1116 University of Lorraine   (France)

^d UNIVERSITY HOSPITAL OF NANCY   (France)

^e Cardiovascular and Renal Clinical Trialists (INI CRCT)   (France)

^f Cardiovascular Clinical Studies   (United States)

^g BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^h TUFTS MEDICAL CENTER   (United States)

Author keywords

Blood pressure; Heart failure; Pharmacology; Prognosis

Indexed keywords

LOSARTAN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST;

ADULT; AGED; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE MONITORING; BLOOD PRESSURE VARIABILITY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; FEMALE; FOLLOW UP; HEART EJECTION FRACTION; HEART FAILURE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTOLIC BLOOD PRESSURE; AMBULATORY CARE; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED STUDY; DIET THERAPY; DOUBLE BLIND PROCEDURE; DRUG EFFECTS; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; RETROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA; TIME FACTOR; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; BLOOD PRESSURE; BLOOD PRESSURE DETERMINATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HUMANS; LOSARTAN; MALE; MIDDLE AGED; OFFICE VISITS; PROGNOSIS; RETROSPECTIVE STUDIES; STROKE VOLUME; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 84929149149     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.03.169     Document Type: Article

References (19)

1. (MAGGIC). M-aGGiCHF, The survival of patientswith heart failurewith preserved or reduced left ventricular ejection fraction: An individual patient data meta-analysis, Eur. Heart J. 33 (2012) 1750-1757.
2. A.L. Bui, T.B. Horwich, G.C. Fonarow, Epidemiology and risk profile of heart failure, Nat. Rev. Cardiol. 8 (2011) 30-41.
3. C.E. Raphael, Z.I. Whinnett, J.E. Davies, et al., Quantifying the paradoxical effect of higher systolic blood pressure on mortality in chronic heart failure, Heart 95 (2009) 56-62.
4. V. Regnault, J. Lagrange, A. Pizard, et al., Opposite predictive value of pulse pressure and aortic pulse wave velocity on heart failure with reduced left ventricular ejection fraction: Insights from an eplerenone post-acute myocardial infarction heart failure efficacy and survival study (EPHESUS) substudy, Hypertension 63 (2014) 105-111.
5. G. Guder, S. Frantz, J. Bauersachs, et al., Reverse epidemiology in systolic and nonsystolic heart failure: Cumulative prognostic benefit of classical cardiovascular risk factors, Circ. Heart Fail. 2 (2009) 563-571.
6. P.M. Rothwell, Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension, Lancet 375 (2010) 938-948.
7. G. Mancia, Prognostic value of long-term blood pressure variability: The evidence is growing, Hypertension 57 (2011) 141-143.
8. P. Gibelin, E. Spillner, S. Bonnan, T. Chevallier, Non-invasive blood pressure variability in chronic heart failure: Characteristics and prognostic value, Arch. Mal. Coeur Vaiss. 96 (2003) 955-962.
9. P.M. Rothwell, S.C. Howard, E. Dolan, et al., Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension, Lancet 375 (2010) 895-905.
10. P. Rossignol, J. Cridlig, P. Lehert, M. Kessler, F. Zannad, Visit-to-visit blood pressure variability is a strong predictor of cardiovascular events in hemodialysis: Insights from FOSIDIAL, Hypertension 60 (2012) 339-346.
11. P. Rossignol, M. Kessler, F. Zannad, Visit-to-visit blood pressure variability and risk for progression of cardiovascular and renal diseases, Curr. Opin. Nephrol. Hypertens. 22 (2013) 59-64.
12. M.A. Konstam, P.A. Poole-Wilson, K. Dickstein, et al., Design of the heart failure endpoint evaluation of all-antagonist losartan (HEAAL) study in patients intolerant to ACE-inhibitor, Eur. J. Heart Fail. 10 (2008) 899-906.
13. P.M. Rothwell, S.C. Howard, E. Dolan, et al., Effects of beta blockers and calciumchannel blockers on within-individual variability in blood pressure and risk of stroke, Lancet Neurol. 9 (2010) 469-480.
14. M.A. Konstam, J.D. Neaton, K. Dickstein, et al., Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (heaal study): A randomised, double-blind trial, Lancet 374 (2009) 1840-1848.
15. K.P. Burnham, D.R. Anderson, Model Selection and Inference: A Practical Information-Theoretic Approach, Springer-Verlag, New York, 1998.
16. D.Y. Lin, L.J. Wei, Z. Ying, Checking the Cox model with cumulative sums of martingale-based residuals, Biometrika 80 (1993) 557-572.
17. M.J. Pencina, R.B.S. D'Agostino, R.B.J. D'Agostino, R.S. Vasan, Evaluating the added predictive ability of a newmarker: From area under the ROC curve to reclassification and beyond, Stat. Med. 27 (2008) 157-172.
18. P. Muntner, D. Shimbo, M. Tonelli, K. Reynolds, D.K. Arnett, S. Oparil, The relationship between visit-to-visit variability in systolic blood pressure and all-cause mortality in the general population: Findings from NHANES III, 1988 to 1994, Hypertension 57 (2011) 160-166.
19. A.J.Webb, U. Fischer, Z. Mehta, P.M. Rothwell, Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: A systematic review and meta-analysis, Lancet 375 (2010) 906-915.