Plasminogen Activator Inhibitor-1 in cigarette smoke exposure and influenza A Virus infection-induced lung injury

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Bhandary, Yashodhar P ^a   Shetty, Shwetha K ^a   Marudamuthu, Amarnath S ^a   Midde, Krishna K ^a   Ji, Hong Long ^a   Shams, Homoyoun ^a   Subramaniam, Renuka ^a   Fu, Jian ^b   Idell, Steven ^a   Shetty, Sreerama ^a  

^a Baylor UT Houston Center for AIDS Research   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CAVEOLIN 1; CIGARETTE SMOKE; EOSINOPHIL ASSOCIATED RNASE1; MESSENGER RNA; MYELOPEROXIDASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN P53; RIBONUCLEASE; UNCLASSIFIED DRUG; CAVEOLIN-1 (82-101); LEUKOCYTE ELASTASE; LUCIFERASE; PEPTIDE FRAGMENT; PEROXIDASE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ISOLATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; EXPOSURE; HEMAGGLUTINATION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLUENZA A; LUNG ALVEOLUS EPITHELIUM CELL; LUNG INJURY; LUNG PARENCHYMA; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING; WILD TYPE; ANIMAL; C57BL MOUSE; COMPLICATION; DRUG EFFECTS; ENZYMOLOGY; GENETICS; INFLUENZA; INFLUENZA A VIRUS; LUNG; METABOLISM; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; PHYSIOLOGY; PROMOTER REGION; SMOKING; VIROLOGY;

INFLUENZA A VIRUS; MUS; MUS MUSCULUS;

ALVEOLAR EPITHELIAL CELLS; ANIMALS; APOPTOSIS; CAVEOLIN 1; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; LEUKOCYTE ELASTASE; LUCIFERASES; LUNG; LUNG INJURY; MICE, INBRED C57BL; ORTHOMYXOVIRIDAE INFECTIONS; PEPTIDE FRAGMENTS; PEROXIDASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROMOTER REGIONS, GENETIC; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84929071099     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0123187     Document Type: Article

References (55)

1. Doll R, Peto R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst. 1981; 66:1191-1308. PMID: 7017215
2. Jinot J, Bayard S. Respiratory health effects of passive smoking: EPA's weight-of-evidence analysis. J Clin Epidemiol. 1994; 47:339-349. PMID: 7730859
3. Heffner JE, Mularski RA, Calverley PM. COPD performance measures: missing opportunities for improving care. Chest. 2010; 137(5):1181-9. doi: 10.1378/chest.09-2306 PMID: 20348199
4. Sopori M. Effects of cigarette smoke on the immune system. Nat. Rev. Immunol. 2002; 2:372-377. PMID: 12033743
5. Kotani N, Kushikata T, Hashimoto H, Sessler DI, Muraoka M, Matsuki A. Recovery of intraoperative microbicidal and inflammatory functions of alveolar immune cells after a tobacco smoke-free period. Anesthesiology. 2001; 94(6):999-1006. PMID: 11465626
6. Juhan-Vague I, Moerman B, De Cock F, Aillaud MF, Collen D. Plasma levels of a specific inhibitor of tis-sue- type plasminogen activator (and urokinase) in normal and pathological conditions. Thromb Res. 1984; 33:523-530. PMID: 6426082
7. Kruithof EK, Gudinchet A, Bachmann F. Plasminogen activator inhibitor 1 and plasminogen activator inhibitor 2 in various disease states. Thromb Haemost.1988; 59:7-12. PMID: 3129809
8. Vassalli JD, Sappino AP, Belin D. The plasminogen activator/plasmin system. J Clin Invest. 1991; 88:1067-1072. PMID: 1833420
9. Cho SH, Tam SW, Demissie-Sanders S, Filler SA, Oh CK. Production of plasminogen activator inhibitor-1 by human mast cells and its possible role in asthma. J Immunol. 2000; 165:3154-3161. PMID: 10975829
10. Eitzman DT, McCoy RD, Zheng X, Fay WP, Shen T, Ginsburg D, et al. Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J Clin Invest. 1996; 97:232-237. PMID: 8550840
11. Cho SH, Ryu CH, Oh CK. Plasminogen activator inhibitor-1 in the pathogenesis of asthma. Exp Biol Med (Maywood). 2004; 229:138-146. PMID: 14734792
12. Sisson TH, Simon RH. The plasminogen activation system in lung disease. Curr Drug Targets. 2007; 8:1016-1029. PMID: 17896953
13. Kucharewicz I, Kowal K, Buczko W, Bodzenta-Lukaszyk A. The plasmin system in airway remodeling. Thromb Res. 2003; 112:1-7. PMID: 15013265
14. Zidovetzki R, Chen P, Fisher M, Hofman FM, Faraci FM. Nicotine increases plasminogen activator inhibitor-1 production by human brain endothelial cells via protein kinase C-associated pathway. Stroke.1999; 30:651-655. PMID: 10066866
15. Simpson AJ, Gray RS, Moore NR, Booth NA. The effects of chronic smoking on the fibrinolytic potential of plasma and platelets. Br J Haematol. 1997; 97:208-213. PMID: 9136967
16. Bhandary YP, Shetty SK, Marudamuthu AS, Gyetko MR, Idell S, Gharaee-kermani M, et al. Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic system. Am J Physiol Lung Cell Mol Physiol. 2012; 302(5):L463-73. doi: 10.1152/ajplung.00099.2011 PMID: 22140072
17. Shetty SK, Bhandary YP, Marudamuthu AS, Abernathy D, Velusamy T, Starcher B, et al. Regulation of airway and alveolar epithelial cell apoptosis by p53-Induced plasminogen activator inhibitor-1 during cigarette smoke exposure injury. Am J Respir Cell Mol Biol. 2012; 47(4):474-83. doi: 10.1165/rcmb.2011-0390OC PMID: 22592924
18. Shetty S, Shetty P, Idell S, Velusamy T, Bhandary YP, Shetty RS. Regulation of plasminogen activator inhibitor-1 expression by tumor suppressor protein p53. J Biol Chem. 2008; 283:19570-19580. doi: 10.1074/jbc.M710268200 PMID: 18469003
19. Corti M, Brody AR, Harrison JH. Isolation and primary culture of murine alveolar type II cells. Am J Respir Cell Mol Biol. 1996; 14:309-315. PMID: 8600933
20. Dobbs LG. Isolation and culture of alveolar type II cells. Am J Physiol Lung Cell Mol Physiol.1990; 258: L134-L147
21. Bhandary YP, Shetty SK, Marudamuthu AS, Ji HL, Neuenschwander PF, Boggaram V, et al. Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1. Am J Pathol. 2013; 183(1):131-43. doi: 10.1016/j.ajpath.2013.03.022 PMID: 23665346
22. Marudamuthu AS, Bhandary YP, Shetty SK, Fu J, Sathish V, Prakash YS, et al. Role of the urokinase-fibrinolytic system in epithelial mesenchymal transition during lung injury. Am J Pathol. 2015; 185 (1):55-68. doi: 10.1016/j.ajpath.2014.08.027 PMID: 25447049
23. Carp H, Janoff A. Possible mechanisms of emphysema in smokers: in vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants. Am Rev Respir Dis. 1978; 118:617-621. PMID: 101105
24. Huang FF, Barnes PF, Feng Y, Donis R, Chroneos ZC, Idell S, et al. GM-CSF in the lung protects against lethal influenza infection. Am J Respir Crit Care Med. 2011; 184(2):259-68. doi: 10.1164/rccm.201012-2036OC PMID: 21474645
25. Shetty S, Bhandary YP, Shetty SK, Velusamy T, Shetty P, Bdeir K, et al. Induction of tissue factor by urokinase in lung epithelial cells and in the lungs. Am J Respir Crit Care Med. 2010; 181:1355-1366. doi: 10.1164/rccm.200901-0015OC PMID: 20194819
26. Yu HP, Yang S, Hsieh YC, Choudhry MA, Bland KI, Chaudry IH. Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1. Am J Physiol Lung Cell Mol Physiol. 2006; 291(3):L400-6. PMID: 16556724
27. Rana SN, Li X, Chaudry IH, Bland KI, Choudhry MA. Inhibition of IL-18 reduces myeloperoxidase activity and prevents edema in intestine following alcohol and burn injury. J Leukoc Biol. 2005; 77: 719-728. PMID: 15728717
28. O'Reilly MA, Yee M, Buczynski BW, Vitiello PF, Keng PC, Welle SL, et al. Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1. Am J Pathol. 2012; 181(2):441-51. doi: 10.1016/j.ajpath.2012.05.005 PMID: 22677423
29. Foronjy RF, Mercer B A, Maxfield MW, Powell CA, Armiento JD. Structural emphysema does not correlate with lung compliance: lesson from the mouse smoking model. Exp Lung Research. 2005; 31:547-562. PMID: 16019987
30. Morrow SAM, Lauer T, Collaco JM, Yee M, Reilly M O, Mitzner W, et al. Neonatal hyperoxia contributes additively to cigarette smoke-induced chronic obstructive pulmonary disease changes in adult mice. Am J Respir Cell Mol Biol. 2011; 45: 610-616. doi: 10.1165/rcmb.2010-0259OC PMID: 21239606
31. Fujihara M, Nagai N, Sussan TE, Biswal S, Handa JT. Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice. PLoS One. 2008; 3: e3119. doi: 10.1371/journal.pone.0003119 PMID: 18769672
32. Simet SM, Sisson JH, Pavlik JA, Devasure JM, Boyer C, Liu X, et al. Long term cigarette smoke exposure in a mouse model of ciliated epithelial cell function. Am J Respir Cell Mol Biol. 2010; 43: 635-640. doi: 10.1165/rcmb.2009-0297OC PMID: 20042711
33. Arcavi L, Benowitz NL. Cigarette smoking and infection. Arch Intern Med. 2004; 164: 2206-2216. PMID: 15534156
34. Masha AE, Reynaldo S, EL-Amin AN. Is smoking risk factor for influenza hospitalization and death. The J of Inf Dis. 2010; 201; 794-795
35. Center for Disease Control and Prevention Smoking and Influenza. http://www.cdc.gov/flu/protect/smoking.htm. 2010
36. Feng Y, Kong Y, Barnes PF, Huang FF, Klucar P, Wang X, et al. Exposure to cigarette smoke inhibits the pulmonary T-cell response to influenza virus and Mycobacterium tuberculosis. Infect Immun. 2011; 79 (1):229-37. doi: 10.1128/IAI.00709-10 PMID: 20974820
37. Maestrelli P, Saetta M, Mapp CE, Fabbri L M. Remodeling in response to infection and injury. Airway inflammation and hypersecretion of mucus in smoking subjects with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 20011; 64:S76-S80.
38. Rangasamy T, Misra V, Zhen L, Tankersley CG, Tuder RM, Biswal S. Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression. Am J Physiol Lung Cell Mol Physiol. 2009; 296(6):L888-900. doi: 10.1152/ajplung.90369.2008 PMID: 19286929
39. Hurd S. The impact of COPD on lung health worldwide: epidemiology and incidence. Chest. 2000; 117 (2):1S-4S. PMID: 10673465
40. Hoshino Y, Mio T, Nagai S, Miki H, Ito I, Izumi T. Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line. Am J Physiol Lung Cell Mol Physiol. 2001; 281:L509-L516. PMID: 11435227
41. Gelbman BD, Heguy A, O'Connor TP, Zabner J, Crystal RG. Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis. Respir Res. 2007; 8:10. PMID: 17288615
42. Abboud RT, Vimalanathan S. Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema. Int J Tuberc Lung Dis. 2008; 12(4):361-7. PMID: 18371259
43. Pletz MW, Ioanas M, de Roux A, Burkhardt O, Lode H. Reduced spontaneous apoptosis in peripheral blood neutrophils during exacerbation of COPD. Eur Respir J. 2004; 23(4):532-7. PMID: 15083750
44. Dibbert B, Weber M, Nikolaizik W.H, Vogt P, Schöni MH, Blasser k, et al. Cytokine- mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation. Proc Natl Acad Sci USA. 1999; 96: 13330-13335. PMID: 10557320
45. Idell S. Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med. 2003; 31: S213-S220. PMID: 12682443
46. Balsara RD, Ploplis VA. Plasminogen activator inhibitor-1: the double-edged sword in apoptosis. Thromb Haemost. 2008; 100:1029-1036. PMID: 19132226
47. Park YJ, Liu G, Lorne EF, Zhao X, Wang J. PAI-1 inhibits neutrophil efferocytosis. Proc Natl Acad Sci U S A. 2008; 105:11784-11789, doi: 10.1073/pnas.0801394105 PMID: 18689689
48. Robbins CS, Bauer CM, Vujicic N, Gaschler GJ, Lichty BD, Brown EG, et al. Cigarette smoke impacts immune inflammatory responses to influenza in mice. Am J Respir Crit Care Med. 2006; 174 (12):1342-1351. PMID: 17023734
49. Gualano RC, Hansen MJ, Vlahos R, Jones JE, Park-Jones RA, Deliyannis G, et al. Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice. Respir Res. 2008; 9:53 doi: 10.1186/1465-9921-9-53 PMID: 18627612
50. Turpin E, Luke K, Jones J, Tumpey T, Konan K, Schultz-Cherry S, et al. Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication. J Virol. 2005; 79(14):8802-11. PMID: 15994774
51. Technau-Ihling K, Ihling C, Kromeier J, Brandner G. Influenza A virus infection of mice induces nuclear accumulation of the tumorsuppressor protein p53 in the lung. Arch Virol. 2001; 146:1655-1666. PMID: 11699953
52. Wu W, Booth JL, Duggan ES, Wu S, Patel KB, Coggeshall KM, et al. Innate immune response to H3N2 and H1N1 influenza virus infection in a human lung organ culture model. Virology. 2010; 20; 396 (2):178-88. doi: 10.1016/j.virol.2009.10.016 PMID: 19913271
53. Kosmider B, Messier EM, Janssen WJ, Nahreini P, Wang J, Hartshorn KL, et al. Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus. Respir Res. 2012; 6; 13:43. doi: 10.1093/jscr/2012.6.13 PMID: 24960682
54. Rosenberg HF. RNase A ribonucleases and host defense: an evolving story. J Leukoc Biol. 2008; 83 (5):1079-87. doi: 10.1189/jlb.1107725 PMID: 18211964
55. Cho S, Beintema JJ, Zhang J. The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. Genomics 2005; 85(2):208-20. PMID: 15676279