Seizures after heart transplantation - Two cases of non-immunosuppressant drug interactions in young patients

Annals of Transplantation

Volumn 19, Issue 1, 2014, Pages 417-420

  Urbanowicz, Tomasz ^a   Pawłowska, Magdalena ^a   Buczkowski, Piotr ^a   Perek, Bartłomiej ^a   Baszyńska Wachowiak, Hanna ^a   Straburzyńska Migaj, Ewa ^a   Jemielity, Marek ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Drug interactions; Epilepsy; Heart transplantation; Metoclopramide; Theophylline

Indexed keywords

BENZODIAZEPINE; METOCLOPRAMIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID; TACROLIMUS; THEOPHYLLINE; THYMOCYTE ANTIBODY; ANTIEMETIC AGENT; DOPAMINE 2 RECEPTOR BLOCKING AGENT; PHOSPHODIESTERASE INHIBITOR;

ADULT; AORTA CLAMPING; ARTICLE; ATRIOVENTRICULAR BLOCK; BRADYCARDIA; CASE REPORT; CONSTIPATION; DRUG BLOOD LEVEL; DRUG OVERDOSE; ECHOCARDIOGRAPHY; FEMALE; GASTROINTESTINAL SYMPTOM; GRAFT RECIPIENT; HEART LEFT VENTRICLE FUNCTION; HEART TRANSPLANTATION; HEART VENTRICLE TACHYCARDIA; HEARTBURN; HUMAN; IMMUNE DEFICIENCY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PERIOD; SEIZURE; ADVERSE EFFECTS; BLOOD; BRAIN; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG INTERACTION; EPILEPSY, TONIC-CLONIC; PATHOLOGY; POSTOPERATIVE COMPLICATIONS;

ADULT; ANTIEMETICS; BRADYCARDIA; BRAIN; DOPAMINE D2 RECEPTOR ANTAGONISTS; DRUG INTERACTIONS; EPILEPSY, TONIC-CLONIC; FEMALE; HEART TRANSPLANTATION; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; METOCLOPRAMIDE; PHOSPHODIESTERASE INHIBITORS; POSTOPERATIVE COMPLICATIONS; THEOPHYLLINE;

EID: 84929045568     PISSN: 14259524     EISSN: None     Source Type: Journal    
DOI: 10.12659/AOT.890743     Document Type: Article

References (31)

1. Pless M, Zivkovic SA: Neurologic complications of transplantation. Neurologist, 2002; (8): 107-20
2. Cemillan CA, Alonso-Pulpon L, Burgos-Lazaro R et al: Neurological complications in a series of 205 orthotopic heart transplant patients. Rev Neurol, 2004; 38: 906-12
3. Zierer A, Melby SJ, Voeller RK et al: Significance of neurologic complications in the modern era of of cardiac transplantation. Ann Thorac Surg, 2007; 83: 1684-90
4. Perez-Miralles F, Sanchez-Manso JC, Almenar-Bonet L et al: Incidence and risk factors for neurologic complications after heart transplantation. Transplant Proc, 2005; 37: 4067-70
5. Cemillan CA, Alonson-Pulpon L, Burgos-Lazaro R et al: Neurological complications in a series of 205 orthotopic heart transplant patients. Rev Neurol, 2004; 38: 906-12
6. Senzolo M, Ferronato C, Burra P: Neurologic complications after solid organ transplantation-review. Tansplan Inter, 2009; 22: 269-78
7. Jarquin-Valdivia AA, Wijddicks EFM, McGregor C: Neurologic complications following heart transplantation in the modern era: decrease incidence, but postoprative stroke remains prevalent. Transplant Proc, 1999; 31: 2161-62
8. Jemenez-Perez M, Lozano Rey JM, Marin Garcia D et al: Efficancy and safety of monotherapy with mycophenolate mofetil in liver transplantation. Transplant Proc, 2006; 38: 2480-81
9. Eidelman BH, Abu-Elmagd K, Wilson J et al: Neurological complications of FK 506. Transplan Proc, 1991; 93: 3175-78
10. Shepard PW, St. Louis KE: Seizure Treatment in Transplant Patients. Curr Treat Options Neurol, 2012; 14(4): 332-47
11. Sarnaik AP, Meert K, Hackbarth R et al: Management of hyponatremic seizures in children with hypertonic saline: a safe and effective strategy. Crit Care Med, 1991; 19: 758-62
12. Thompson CB, June CH, Sullivan KM et al: Association between cyclosporin neurotoxicity and hypo-magnesaemia. Lancet, 1984; 2: 1116-20
13. Conti DJ, Rubin RH: Infection of the central nervous system in organ transplant patients. Neurol Clin, 1988; 6(2): 241-60
14. Bonham CA, Dominguez EA, Fukui MB et al: Central nervous system lesions in liver transplant recipients: prospective assessment of indications for biopsy and implications for management. Transplantation, 1998; 66(12): 1596-604
15. Selby R, Ramirez CB, Singh R et al: Brain abscess in solid organ transplant recipients receiving cyclo-sporine-based immunosuppression. Arch Surg, 1997; 132: 304-10
16. Miller LW: Cyclosporine-associated neurotoxicity: the need for a better guide for immunosuppressive therapy. Circulation, 1996; 94: 1209-11
17. Gijtenbeek JM, Van den Bent MJ, Vecht CJ: Cyclosporine neurotoxicity: a review. J Neurol, 1999; 246: 339-46
18. Singh N, Bonham A, Fukui M: Immunosuppressive-associated leukoencephalopathy in organ transplant recipients. Transplantation, 2000; 69: 467-72
19. Lado FA, Moshe SL: How do seizures stop? Epilepsia, 2008; 49: 1651-64
20. Boison D: 10 Methylxanthines, seizures and excitotoxicity. Handb Exp Pharmacol, 2011; 200: 251-66
21. Leopold NA: Prolonged metoclopramide-induced dyskinetic reaction. Neurology, 1984; 34: 238-39
22. Al Zaben AA, Al Herbish AS: Neurological side effects associated with unnecessary use of metoclopramide in children. Ann Saudi Med, 1995; 15(2): 183-84
23. Grimes JD, Hassan MN, Preston DN: Adverse neurologic effects of metoclopramide. Can Med Assoc J, 1982; 126: 23-25
24. Desta Z, Wu GM, Morocho AM et al: The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6. Drug Metab Dispos, 2002; 30: 336-43
25. Muller DM, Shinkai T, De Luca V, Kennedy JL: Clinical implications of pharmacogenomics for tardive dyskinesia. Pharmacogenomics J, 2004; 4: 77-87
26. Abell TL, Bernstein RK, Cutts T et al: Treatment of gastroparesis: a multidisciplinary clinical review. Neurogastroenteral Motil, 2006; 18: 263-83
27. Bozzi Y, Borrelli E: Dopamine in neurotoxicity and neuroprotection: what do D2 receptors have to do with it? Trends Neurosci, 226; 29: 167-74
28. Starr MS: The role of dopamine in epilepsy. Synapse, 1996; 22(2): 159-94
29. Gangarossa G, Di Benedetto M, O'Sulivan Gdunleavy M et al: Consulvant doses of dopamine D1 receptor agonist result in Erk-dependent increasea in Zif268 and Arc/Arg3.1 expression in mouse dentate gyrus. PLoS One, 2011; 6(5): e19415
30. Rocha L, Alonso-Vanegas M, Villeda-Hernandez J et al: Dopamine abnormalities i the neocortex of patients with temporal lobe epilepsy. Neurobiol Dis, 2012; 45: 499-507
31. Zwillich CW, Sutton FD, Neff TA et al: Theophylline-induced seizures in adults. Ann Intern Med, 1975; 82: 784-87