Simplified antibiotic regimens compared with injectable procaine benzylpenicillin plus gentamicin for treatment of neonates and young infants with clinical signs of possible serious bacterial infection when referral is not possible: A randomised, open-label, equivalence trial

The Lancet

Volumn 385, Issue 9979, 2015, Pages 1767-1776

  Tshefu, Antoinette ^a   Lokangaka, Adrien ^a   Ngaima, Serge ^a   Engmann, Cyril ^b   Esamai, Fabian ^c   Gisore, Peter ^c   Ayede, Adejumoke Idowu ^d   Falade, Adegoke Gbadegesin ^d   Adejuyigbe, Ebunoluwa A ^e   Anyabolu, Chineme Henry ^e   Wammanda, Robinson D ^f   Ejembi, Clara L ^f   Ogala, William N ^f   Gram, Lu ^g   Cousens, Simon ^g  

^a Kinshasa School of Public Health   (Congo)

^b IL   (United States)

^c MOI UNIVERSITY   (Kenya)

^d UNIVERSITY OF IBADAN   (Nigeria)

^e OBAFEMI AWOLOWO UNIVERSITY   (Nigeria)

^f AHMADU BELLO UNIVERSITY   (Nigeria)

^g LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; CEFTRIAXONE; GENTAMICIN; PROCAINE PENICILLIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; BODY WEIGHT; COMPUTER; CONGO; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; DRUG TREATMENT FAILURE; FEMALE; FOLLOW UP; GROUPS BY AGE; HEALTH AUXILIARY; HEALTH PRACTITIONER; HOME; HUMAN; INFANT; INJECTION SITE ABSCESS; KENYA; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MULTICENTER STUDY; NEWBORN; NEWBORN INFECTION; NIGERIA; NURSE; OPEN STUDY; OUTCOME ASSESSMENT; PARENT; PATIENT COMPLIANCE; PATIENT REFERRAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK REDUCTION; RURAL AREA; TREATMENT DURATION; WORLD HEALTH ORGANIZATION; ANOREXIA; BACTERIAL INFECTIONS; CLINICAL TRIAL; COMPARATIVE STUDY; COMPLICATION; DEMOCRATIC REPUBLIC CONGO; FEVER; INTRAMUSCULAR DRUG ADMINISTRATION; LETHARGY; ORAL DRUG ADMINISTRATION; SINGLE BLIND PROCEDURE; THERAPEUTIC EQUIVALENCE; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; AMOXICILLIN; ANOREXIA; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; DEMOCRATIC REPUBLIC OF THE CONGO; FEMALE; FEVER; GENTAMICINS; HUMANS; INFANT; INFANT, NEWBORN; INJECTIONS, INTRAMUSCULAR; KENYA; LETHARGY; MALE; NIGERIA; PENICILLIN G PROCAINE; REFERRAL AND CONSULTATION; SINGLE-BLIND METHOD; THERAPEUTIC EQUIVALENCY; TREATMENT OUTCOME;

EID: 84929031567     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(14)62284-4     Document Type: Article

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