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Volumn 45, Issue 5, 2015, Pages 1535-1547

Premature thymic involution is independent of structural plasticity of the thymic stroma

Author keywords

FVB N mouse; Involution; Pro T cells; Thymic epithelium cells; Thymus; Vascularization

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHIMERA; CONTROLLED STUDY; ENDOTHELIUM; EPITHELIUM CELL; GENETIC REGULATION; INVOLUTION; MOUSE; NONHUMAN; PRE T LYMPHOCYTE; PREMATURE THYMIC INVOLUTION; PREMATURITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; T LYMPHOCYTE; THYMIC STROMA; THYMUS; THYMUS DISEASE; AGING; ANIMAL; ATROPHY; C57BL MOUSE; CELL DIFFERENTIATION; FEMALE; HUMAN; IMMUNOLOGY; INBRED MOUSE STRAIN; INFANT; MALE; NEWBORN; PATHOLOGY; SPECIES DIFFERENCE; STROMA CELL; VASCULAR ENDOTHELIUM; VASCULARIZATION;

EID: 84929027825     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445277     Document Type: Article
Times cited : (9)

References (42)
  • 1
    • 79959642720 scopus 로고    scopus 로고
    • The golden anniversary of the thymus
    • Miller, J. F., The golden anniversary of the thymus. Nat. Rev. Immunol. 2011. 11: 489-495.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 489-495
    • Miller, J.F.1
  • 2
    • 49749221890 scopus 로고
    • Immunological function of the thymus
    • Miller, J. F., Immunological function of the thymus. Lancet 1961. 2: 748-749.
    • (1961) Lancet , vol.2 , pp. 748-749
    • Miller, J.F.1
  • 3
    • 3242747324 scopus 로고    scopus 로고
    • Regulation of thymus size by competition for stromal niches among early T cell progenitors
    • Prockop, S. E. and Petrie, H. T., Regulation of thymus size by competition for stromal niches among early T cell progenitors. J. Immunol. 2004. 173: 1604-1611.
    • (2004) J. Immunol , vol.173 , pp. 1604-1611
    • Prockop, S.E.1    Petrie, H.T.2
  • 4
    • 33645086366 scopus 로고    scopus 로고
    • Cyclical mobilization and gated importation of thymocyte progenitors in the adult mouse: evidence for a thymus-bone marrow feedback loop
    • Goldschneider, I., Cyclical mobilization and gated importation of thymocyte progenitors in the adult mouse: evidence for a thymus-bone marrow feedback loop. Immunol. Rev. 2006. 209: 58-75.
    • (2006) Immunol. Rev. , vol.209 , pp. 58-75
    • Goldschneider, I.1
  • 5
    • 33645784821 scopus 로고    scopus 로고
    • Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus
    • Schnell, F. J., Zoller, A. L., Patel, S. R., Williams, I. R. and Kersh, G. J., Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus. J. Immunol. 2006. 176: 4740-4747.
    • (2006) J. Immunol. , vol.176 , pp. 4740-4747
    • Schnell, F.J.1    Zoller, A.L.2    Patel, S.R.3    Williams, I.R.4    Kersh, G.J.5
  • 6
    • 0035808785 scopus 로고    scopus 로고
    • The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice
    • Foss, D. L., Donskoy, E. and Goldschneider, I., The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice. J. Exp. Med. 2001. 193: 365-374.
    • (2001) J. Exp. Med. , vol.193 , pp. 365-374
    • Foss, D.L.1    Donskoy, E.2    Goldschneider, I.3
  • 8
    • 65549089187 scopus 로고    scopus 로고
    • Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25
    • Gossens, K., Naus, S., Corbel, S. Y., Lin, S., Rossi, F. M., Kast, J. and Ziltener, H. J., Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25. J. Exp. Med. 2009. 206: 761-778.
    • (2009) J. Exp. Med. , vol.206 , pp. 761-778
    • Gossens, K.1    Naus, S.2    Corbel, S.Y.3    Lin, S.4    Rossi, F.M.5    Kast, J.6    Ziltener, H.J.7
  • 9
    • 0033735838 scopus 로고    scopus 로고
    • Microenvironmental regulation of T cell development in the thymus
    • Anderson, G., Harman, B. C., Hare, K. J. and Jenkinson, E. J., Microenvironmental regulation of T cell development in the thymus. Semin. Immunol. 2000. 12: 457-464.
    • (2000) Semin. Immunol. , vol.12 , pp. 457-464
    • Anderson, G.1    Harman, B.C.2    Hare, K.J.3    Jenkinson, E.J.4
  • 10
    • 33845239216 scopus 로고    scopus 로고
    • Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
    • Gray, D. H., Seach, N., Ueno, T., Milton, M. K., Liston, A., Lew, A. M., Goodnow, C. C. et al., Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood 2006. 108: 3777-3785.
    • (2006) Blood , vol.108 , pp. 3777-3785
    • Gray, D.H.1    Seach, N.2    Ueno, T.3    Milton, M.K.4    Liston, A.5    Lew, A.M.6    Goodnow, C.C.7
  • 11
    • 84860351016 scopus 로고    scopus 로고
    • Molecular control over thymic involution: from cytokines and microRNA to aging and adipose tissue
    • Dooley, J. and Liston, A., Molecular control over thymic involution: from cytokines and microRNA to aging and adipose tissue. Eur. J. Immunol. 2012. 42: 1073-1079.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 1073-1079
    • Dooley, J.1    Liston, A.2
  • 12
    • 67649410701 scopus 로고    scopus 로고
    • An evolutionary perspective on the mechanisms of immunosenescence
    • Shanley, D. P., Aw, D., Manley, N. R. and Palmer, D. B., An evolutionary perspective on the mechanisms of immunosenescence. Trends Immunol. 2009. 30: 374-381.
    • (2009) Trends Immunol. , vol.30 , pp. 374-381
    • Shanley, D.P.1    Aw, D.2    Manley, N.R.3    Palmer, D.B.4
  • 13
    • 57249088996 scopus 로고    scopus 로고
    • Strategies for reconstituting and boosting T cell-based immunity following haematopoietic stem cell transplantation: pre-clinical and clinical approaches
    • Chidgey, A. P., Seach, N., Dudakov, J., Hammett, M. V. and Boyd, R. L., Strategies for reconstituting and boosting T cell-based immunity following haematopoietic stem cell transplantation: pre-clinical and clinical approaches. Semin. Immunopathol. 2008. 30: 457-477.
    • (2008) Semin. Immunopathol. , vol.30 , pp. 457-477
    • Chidgey, A.P.1    Seach, N.2    Dudakov, J.3    Hammett, M.V.4    Boyd, R.L.5
  • 14
    • 46249132015 scopus 로고    scopus 로고
    • Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections
    • Nikolich-Zugich, J., Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections. Nat. Rev. Immunol. 2008. 8: 512-522.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 512-522
    • Nikolich-Zugich, J.1
  • 15
    • 11844275234 scopus 로고    scopus 로고
    • Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses
    • Eaton, S. M., Burns, E. M., Kusser, K., Randall, T. D. and Haynes, L., Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses. J. Exp. Med. 2004. 200: 1613-1622.
    • (2004) J. Exp. Med. , vol.200 , pp. 1613-1622
    • Eaton, S.M.1    Burns, E.M.2    Kusser, K.3    Randall, T.D.4    Haynes, L.5
  • 16
    • 0029918498 scopus 로고    scopus 로고
    • Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice
    • Yang, X., Stedra, J. and Cerny, J., Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice. J. Exp. Med. 1996. 183: 959-970.
    • (1996) J. Exp. Med. , vol.183 , pp. 959-970
    • Yang, X.1    Stedra, J.2    Cerny, J.3
  • 17
    • 58149100407 scopus 로고    scopus 로고
    • The ageing immune system: is it ever too old to become young again?
    • Dorshkind, K., Montecino-Rodriguez, E. and Signer, R. A., The ageing immune system: is it ever too old to become young again? Nat. Rev. Immunol. 2009. 9: 57-62.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 57-62
    • Dorshkind, K.1    Montecino-Rodriguez, E.2    Signer, R.A.3
  • 18
    • 36549062401 scopus 로고    scopus 로고
    • Impact of niche aging on thymic regeneration and immune reconstitution
    • Chidgey, A., Dudakov, J., Seach, N. and Boyd, R., Impact of niche aging on thymic regeneration and immune reconstitution. Semin. Immunol. 2007. 19: 331-340.
    • (2007) Semin. Immunol. , vol.19 , pp. 331-340
    • Chidgey, A.1    Dudakov, J.2    Seach, N.3    Boyd, R.4
  • 19
    • 20344371900 scopus 로고    scopus 로고
    • Insights into thymic aging and regeneration
    • Taub, D. D. and Longo, D. L., Insights into thymic aging and regeneration. Immunol. Rev. 2005. 205: 72-93.
    • (2005) Immunol. Rev. , vol.205 , pp. 72-93
    • Taub, D.D.1    Longo, D.L.2
  • 20
    • 34548637281 scopus 로고    scopus 로고
    • Lymphohematopoietic progenitors do not have a synchronized defect with age-related thymic involution
    • Zhu, X., Gui, J., Dohkan, J., Cheng, L., Barnes, P. F. and Su, D. M., Lymphohematopoietic progenitors do not have a synchronized defect with age-related thymic involution. Aging Cell 2007. 6: 663-672.
    • (2007) Aging Cell , vol.6 , pp. 663-672
    • Zhu, X.1    Gui, J.2    Dohkan, J.3    Cheng, L.4    Barnes, P.F.5    Su, D.M.6
  • 22
    • 77956688908 scopus 로고    scopus 로고
    • Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution
    • Sun, L., Guo, J., Brown, R., Amagai, T., Zhao, Y. and Su, D. M., Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution. Aging Cell 2010. 9: 347-357.
    • (2010) Aging Cell , vol.9 , pp. 347-357
    • Sun, L.1    Guo, J.2    Brown, R.3    Amagai, T.4    Zhao, Y.5    Su, D.M.6
  • 23
    • 60249092412 scopus 로고    scopus 로고
    • Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner
    • Chen, L., Xiao, S. and Manley, N. R., Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner. Blood 2009. 113: 567-574.
    • (2009) Blood , vol.113 , pp. 567-574
    • Chen, L.1    Xiao, S.2    Manley, N.R.3
  • 24
    • 33947192136 scopus 로고    scopus 로고
    • Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging
    • Min, D., Panoskaltsis-Mortari, A., Kuro, O. M., Hollander, G. A., Blazar, B. R. and Weinberg, K. I., Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging. Blood 2007. 109: 2529-2537.
    • (2007) Blood , vol.109 , pp. 2529-2537
    • Min, D.1    Panoskaltsis-Mortari, A.2    Kuro, O.M.3    Hollander, G.A.4    Blazar, B.R.5    Weinberg, K.I.6
  • 25
    • 0035148297 scopus 로고    scopus 로고
    • Ultrastructural study of the FVB/N mouse thymus: presence of an immature epithelial cell in the medulla and premature involution
    • Nabarra, B., Mulotte, M., Casanova, M., Godard, C. and London, J., Ultrastructural study of the FVB/N mouse thymus: presence of an immature epithelial cell in the medulla and premature involution. Dev. Comp. Immunol. 2001. 25: 231-243.
    • (2001) Dev. Comp. Immunol. , vol.25 , pp. 231-243
    • Nabarra, B.1    Mulotte, M.2    Casanova, M.3    Godard, C.4    London, J.5
  • 26
    • 84855931651 scopus 로고    scopus 로고
    • The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-alpha receptor
    • Papadopoulou, A. S., Dooley, J., Linterman, M. A., Pierson, W., Ucar, O., Kyewski, B., Zuklys, S. et al., The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-alpha receptor. Nat. Immunol. 2012. 13: 181-187.
    • (2012) Nat. Immunol. , vol.13 , pp. 181-187
    • Papadopoulou, A.S.1    Dooley, J.2    Linterman, M.A.3    Pierson, W.4    Ucar, O.5    Kyewski, B.6    Zuklys, S.7
  • 27
    • 0023250868 scopus 로고
    • Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interactions is developmentally controlled
    • Kyewski, B. A., Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interactions is developmentally controlled. J. Exp. Med. 1987. 166: 520-538.
    • (1987) J. Exp. Med. , vol.166 , pp. 520-538
    • Kyewski, B.A.1
  • 28
    • 0035898387 scopus 로고    scopus 로고
    • Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development
    • Lind, E. F., Prockop, S. E., Porritt, H. E. and Petrie, H. T., Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development. J. Exp. Med. 2001. 194: 127-134.
    • (2001) J. Exp. Med. , vol.194 , pp. 127-134
    • Lind, E.F.1    Prockop, S.E.2    Porritt, H.E.3    Petrie, H.T.4
  • 29
    • 2942700206 scopus 로고    scopus 로고
    • Reduction in the developmental potential of intrathymic T cell progenitors with age
    • Min, H., Montecino-Rodriguez, E. and Dorshkind, K., Reduction in the developmental potential of intrathymic T cell progenitors with age. J. Immunol. 2004. 173: 245-250.
    • (2004) J. Immunol. , vol.173 , pp. 245-250
    • Min, H.1    Montecino-Rodriguez, E.2    Dorshkind, K.3
  • 30
    • 77952747811 scopus 로고    scopus 로고
    • CD11c(hi) dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes
    • Tzeng, T. C., Chyou, S., Tian, S., Webster, B., Carpenter, A. C., Guaiquil, V. H. and Lu, T. T., CD11c(hi) dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes. J. Immunol. 2010. 184: 4247-4257.
    • (2010) J. Immunol. , vol.184 , pp. 4247-4257
    • Tzeng, T.C.1    Chyou, S.2    Tian, S.3    Webster, B.4    Carpenter, A.C.5    Guaiquil, V.H.6    Lu, T.T.7
  • 33
    • 70349231092 scopus 로고    scopus 로고
    • Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution
    • Yang, H., Youm, Y. H. and Dixit, V. D., Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution. J. Immunol. 2009. 183: 3040-3052.
    • (2009) J. Immunol. , vol.183 , pp. 3040-3052
    • Yang, H.1    Youm, Y.H.2    Dixit, V.D.3
  • 34
    • 0011859014 scopus 로고
    • T lymphocyte pre-cursors adhere to thymic endothelium
    • In Imhof, B. A., Berrih-Aknin, S. and Ezine, S. (Eds.), M. Dekker, New York
    • Ruiz, P., Dunon, D., Hesse, B. and Imhof, B. A., T lymphocyte pre-cursors adhere to thymic endothelium. In Imhof, B. A., Berrih-Aknin, S. and Ezine, S. (Eds.), Lymphatic tissues and in vivo immune responses, M. Dekker, New York, 1991, pp. 963.
    • (1991) Lymphatic tissues and in vivo immune responses , pp. 963
    • Ruiz, P.1    Dunon, D.2    Hesse, B.3    Imhof, B.A.4
  • 36
    • 79960447248 scopus 로고    scopus 로고
    • Skint-1 identifies a common molecular mechanism for the development of interferon-gamma-secreting versus interleukin-17-secreting gammadelta T cells
    • Turchinovich, G. and Hayday, A. C., Skint-1 identifies a common molecular mechanism for the development of interferon-gamma-secreting versus interleukin-17-secreting gammadelta T cells. Immunity 2011. 35: 59-68.
    • (2011) Immunity , vol.35 , pp. 59-68
    • Turchinovich, G.1    Hayday, A.C.2
  • 38
    • 77951621381 scopus 로고    scopus 로고
    • Feeding the fire: the role of defective bone marrow function in exacerbating thymic involution
    • Dudakov, J. A., Khong, D. M., Boyd, R. L. and Chidgey, A. P., Feeding the fire: the role of defective bone marrow function in exacerbating thymic involution. Trends Immunol. 2010. 31: 191-198.
    • (2010) Trends Immunol. , vol.31 , pp. 191-198
    • Dudakov, J.A.1    Khong, D.M.2    Boyd, R.L.3    Chidgey, A.P.4
  • 40
    • 33846867492 scopus 로고    scopus 로고
    • PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches
    • Jenkinson, W. E., Rossi, S. W., Parnell, S. M., Jenkinson, E. J. and Anderson, G., PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches. Blood 2007. 109: 954-960.
    • (2007) Blood , vol.109 , pp. 954-960
    • Jenkinson, W.E.1    Rossi, S.W.2    Parnell, S.M.3    Jenkinson, E.J.4    Anderson, G.5
  • 42
    • 54049121774 scopus 로고    scopus 로고
    • Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation
    • Dooley, J., Erickson, M. and Farr, A. G., Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation. J. Immunol. 2008. 181: 5225-5232.
    • (2008) J. Immunol. , vol.181 , pp. 5225-5232
    • Dooley, J.1    Erickson, M.2    Farr, A.G.3


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