The impact of smoke exposure on the clinical phenotype of alpha-1 antitrypsin deficiency in Ireland: Exploiting a national registry to understand a rare disease

COPD: Journal of Chronic Obstructive Pulmonary Disease

Volumn 12, Issue , 2015, Pages 2-9

  Emmet O'Brien, M ^a   Pennycooke, Kevin ^a   Carroll, Tomás P ^a   Shum, Jonathan ^a   Fee, Laura T ^a   O'Connor, Catherine ^a   Logan, P Mark ^a   Reeves, Emer P ^a   McElvaney, Noel G ^a  

^a BEAUMONT HOSPITAL   (Ireland)

Author keywords

Occupational exposure; Passive smoke; Phenotype; Questionnaire; Radiology; SERPINA1

Indexed keywords

CIGARETTE SMOKE; PASSIVE SMOKING;

ADULT; AGE; ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; BRONCHIECTASIS; CHILDHOOD; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; ENVIRONMENTAL FACTOR; FEMALE; FORCED EXPIRATORY VOLUME; GENE MUTATION; GENETIC SUSCEPTIBILITY; HUMAN; IRELAND; LUNG EMPHYSEMA; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MUTATOR GENE; PASSIVE SMOKING; PHENOTYPE; PRIORITY JOURNAL; REGISTER; SERPINA1 GENE; SMOKING; SMOKING CESSATION; ADVERSE EFFECTS; AGED; ALPHA 1-ANTITRYPSIN DEFICIENCY; COMPLICATION; CROSS-SECTIONAL STUDY; DISEASE COURSE; GENETICS; HEALTH SURVEY; PATHOPHYSIOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; QUESTIONNAIRE; RARE DISEASES; RISK FACTOR; SEVERITY OF ILLNESS INDEX; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALPHA 1-ANTITRYPSIN DEFICIENCY; BRONCHIECTASIS; CROSS-SECTIONAL STUDIES; DISEASE PROGRESSION; FEMALE; HEALTH SURVEYS; HUMANS; IRELAND; MALE; MIDDLE AGED; PHENOTYPE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; RARE DISEASES; REGISTRIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SMOKING; SURVEYS AND QUESTIONNAIRES; TOBACCO SMOKE POLLUTION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84928897706     PISSN: 15412555     EISSN: 15412563     Source Type: Journal    
DOI: 10.3109/15412555.2015.1021913     Document Type: Article

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