Exercise training improves physical fitness in patients with pulmonary arterial hypertension: A systematic review and meta-analysis of controlled trials

BMC Pulmonary Medicine

Volumn 15, Issue 1, 2015, Pages

  Buys, Roselien ^a   Avila, Andrea ^a   Cornelissen, Véronique A ^a  

^a Department of Rehabilitation Sciences ^*  (Belgium)

Author keywords

Exercise capacity; Exercise training; Pulmonary arterial hypertension

Indexed keywords

AEROBIC EXERCISE; ARTICLE; CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION; CONTROLLED CLINICAL TRIAL (TOPIC); DISEASE SEVERITY; EXERCISE; EXERCISE TOLERANCE; FITNESS; FUNCTIONAL STATUS; HEART RATE; HUMAN; META ANALYSIS; OUTCOME ASSESSMENT; OXYGEN CONSUMPTION; PEDRO; PULMONARY HYPERTENSION; RESISTANCE TRAINING; SYSTEMATIC REVIEW; TREADMILL EXERCISE; TREATMENT DURATION; WALKING; HYPERTENSION, PULMONARY; KINESIOTHERAPY; PROCEDURES; QUALITY OF LIFE; TREATMENT OUTCOME;

EXERCISE THERAPY; EXERCISE TOLERANCE; HUMANS; HYPERTENSION, PULMONARY; PHYSICAL FITNESS; QUALITY OF LIFE; TREATMENT OUTCOME;

EID: 84928885058     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/s12890-015-0031-1     Document Type: Article

References (35)

1. Galie N, Hoeper MM, Humbert M, Torbicky A, Vachiery JL, Barbera JA, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J. 2009;30:2493-537.
2. Desai SA, Channick RN. Exercise in patients with pulmonary arterial hypertension. J Cardiopulm Rehabil Prev. 2008;28:12-6.
3. Arena R, Lavie CJ, Milani RV, Myers J, Guazzi M. Cardiopulmonary exercise testing in patients with pulmonary arterial hypertension: an evidence-based review. J Heart Lung Transplant. 2010;29:159-73.
4. Taylor RS, Sagar VA, Davies EJ, Briscoe S, Coats AJ, Ebrahim S, et al. Exercise-based rehabilitation for heart failure. Cochrane Database Syst Rev. 2014;4:CD003331.
5. Langer D, Hendriks E, Burtin C, Probst V, Van Der Schans C, Paterson W, et al. A clinical practice guideline for physiotherapists treating patients with chronic obstructive pulmonary disease based on a systematic review of available evidence. Clin Rehabil. 2009;23:445-62.
6. Vanhees L, Rauch B, Piepoli M, Van Buuren F, Takken T, Börjesson M, et al. Importance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular disease (Part III). Eur J Prev Cardiol. 2012;19:1333-56.
7. Duppen N, Takken T, Hopman MT, Ten Harkel AD, Dulfer K, Utens EM, et al. Systematic review of the effects of physical exercise training programmes in children and young adults with congenital heart disease. Int J Cardiol. 2013;168:3.
8. Physiotherapy evidence database (PEDro).[ http://www.pedro.org.au ]
9. de Morton NA. The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. Aust J Physiother. 2009;55:129-33.
10. Maher CG, Sherrington C, Herbert RD, Moseley AM, Elkins M. Reliability of the PEDro scale for rating quality of randomized controlled trials. Phys Ther. 2003;83:713-21.
11. Follmann D, Elliott P, Suh I, Cutler J. Variance imputation for overviews of clinical trials with continuous response. J Clin Epidemiol. 1992;45:769-73.
12. Dersimonian R, Kacker R. Random-effects model for meta-analysis of clinical trials: an update. Contemp Clin Trials. 2007;28:105-14.
13. Schmidt FL, Oh IS, Hayes TL. Fixed- versus random-effects models in meta-analysis: model properties and an empirical comparison of differences in results. Br J Math Stat Psychol. 2009;62:97-128.
14. Borenstein MHL, Higgins JPT, Rothstein HR. Introduction to meta-analysis. New York: John Wiley & Sons, Ltd; 2009. p. 272-92.
15. Chan L, Chin LM, Kennedy M, Woolstenhulme JG, Nathan SD, Weinstein AA, et al. Benefits of intensive treadmill exercise training on cardiorespiratory function and quality of life in patients with pulmonary hypertension. Chest. 2013;143:333-43.
16. Weinstein AA, Chin LM, Keyser RE, Kennedy M, Nathan SD, Woolstenhulme JG, et al. Effect of aerobic exercise training on fatigue and physical activity in patients with pulmonary arterial hypertension. Respir Med. 2013;107:778-84.
17. Martinez-Quintana E, Miranda-Calderin G, Ugarte-Lopetegui A, Rodriguez-Gonzalez F. Rehabilitation program in adult congenital heart disease patients with pulmonary hypertension. Congenit Heart Dis. 2010;5:44-50.
18. Mereles D, Ehlken N, Kreuscher S, Ghofrani S, Hoeper MM, Halank M, et al. Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation. 2006;114:1482-9.
19. Fox BD, Kassirer M, Weiss I, Raviv Y, Peled N, Shitrit D, et al. Ambulatory rehabilitation improves exercise capacity in patients with pulmonary hypertension. J Card Fail. 2011;17:196-200.
20. Ley S, Fink C, Risse F, Ehlken N, Fischer C, Ley Zaporozhan J, et al. Magnetic resonance imaging to assess the effect of exercise training on pulmonary perfusion and blood flow in patients with pulmonary hypertension. Eur Radiol. 2013;23:324-31.
21. ATS statement. Guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166:111-7.
22. Lacasse Y, Brosseau L, Milne S, Martin S, Wong E, Guyatt GH, et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2002;3:CD003793.
23. Peytremann-Bridevaux I, Staeger P, Bridevaux PO, Ghali WA, Burnand B. Effectiveness of chronic obstructive pulmonary disease-management programs: systematic review and meta-analysis. Am J Med. 2008;121:433-43.
24. Van der Meer S, Zwerink M, van Brussel M, van der Valk P, Wajon E, van der Palen J. Effect of outpatient exercise training programmes in patients with chronic heart failure: a systematic review. Eur J Prev Cardiol. 2012;19(4):795-803.
25. Rasekaba T, Lee AL, Naughton MT, Williams TJ, Holland AE. The six-minute walk test: a useful metric for the cardiopulmonary patient. Intern Med J. 2009;39:495-501.
26. Savarese G, Paolillo S, Costanzo P,D, Amore C, Cecere M, Losco T, et al. Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials. J Am Coll Cardiol. 2012;60:1192-201.
27. Macchia A, Marchioli R, Marfisi R, Scarano M, Levantesi G, Tavazzi L, et al. A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology. Am Heart J. 2007;153:1037-47.
28. Golpe R, Castro-Anon O, Perez-de-Llano LA, Gonzalez Juanatey C, Muniz Fernandez C, Testa Fernandez A, et al. Prognostic significance of six-minute walk test in non-group 1 pulmonary hypertension. Heart Lung. 2014;43:72-6.
29. Hansen JE, Sun XG, Yasunobu Y, Garafano RP, Gates G, Barst RJ, et al. Reproducibility of cardiopulmonary exercise measurements in patients with pulmonary arterial hypertension. Chest. 2004;126:816-24.
30. Paolillo S, Farina S, Bussotti M, Iorio A, PerroneFilardi P, Piepolil MF, et al. Exercise testing in the clinical management of patients affected by pulmonary arterial hypertension. Eur J Prev Cardiol. 2012;19:960-71.
31. Zafrir B. Exercise training and rehabilitation in pulmonary arterial hypertension: rationale and current data evaluation. J Cardiopulm Rehabil Prev. 2013;33:263-73.
32. Groepenhoff H, Vonk-Noordegraaf A, van de Veerdonk MC, Boonstra A, Westerhof N, Bogaard HJ. Prognostic relevance of changes in exercise test variables in pulmonary arterial hypertension. PLoS One. 2013;8:e72013.
33. Chua R, Keogh AM, Byth K, O'Loughlin A. Comparison and validation of three measures of quality of life in patients with pulmonary hypertension. Intern Med J. 2006;36:705-10.
34. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration. BMJ. 2009;339:b2700.
35. Fagard RH, Staessen JA, Thijs L. Advantages and disadvantages of the meta-analysis approach. J Hypertens Suppl. 1996;14:S9-12.