Vernonia amygdalina simultaneously suppresses gluconeogenesis and potentiates glucose oxidation via the pentose phosphate pathway in streptozotocin-induced diabetic rats

BMC Complementary and Alternative Medicine

Volumn 14, Issue 1, 2014, Pages

  Atangwho, Item Justin ^a,c   Yin, Khoo Boon ^b   Umar, Muhammad Ihtisham ^a   Ahmad, Mariam ^a   Asmawi, Mohd Zaini ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

^c UNIVERSITY OF CALABAR   (Nigeria)

Author keywords

Diabetes mellitus; Gene expression; Gluconeogenesis; Mechanism of anti diabetic action; Pentose phosphate patheway; Vernonia amygdalina

Indexed keywords

6 PHOSPHOFRUCTOKINASE; FRUCTOSE BISPHOSPHATASE; GLUCOSE 6 PHOSPHATASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEXOKINASE; METFORMIN; PENTOSE PHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (PYROPHOSPHATE); REACTIVE OXYGEN METABOLITE; VERNONIA AMYGDALINA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; DRUG ISOLATION; EVENING DOSAGE; F16BP GENE; G6PASE GENE; G6PDH GENE; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; GLUCOSE OXIDATION; GYMNANTHEMUM AMYGDALINUM; MALE; MORNING DOSAGE; NONHUMAN; PEPCK GENE; PLANT LEAF; PROTEIN EXPRESSION; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TREATMENT RESPONSE; UPREGULATION;

EID: 84928821582     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-426     Document Type: Article

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