Physical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disability

Arthritis Research and Therapy

Volumn 17, Issue 1, 2015, Pages

  Teichtahl, Andrew J ^a,b   Urquhart, Donna M ^a   Wang, Yuanyuan ^a   Wluka, Anita E ^a   O'Sullivan, Richard ^a,c   Jones, Graeme ^d   Cicuttini, Flavia M ^a  

^a MONASH UNIVERSITY   (Australia)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^c EPWORTH HOSPITAL   (Australia)

^d UNIVERSITY OF TASMANIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BODY MASS; CHRONIC PAIN GRADE QUESTIONNAIRE; CLINICAL ASSESSMENT TOOL; CONFIDENCE INTERVAL; CORRELATION ANALYSIS; DISABILITY; ERECTOR SPINAE MUSCLE; FAT CONTENT; FEMALE; HUMAN; HUMAN EXPERIMENT; INTERVERTEBRAL DISK; LOW BACK PAIN; LUMBOSACRAL SPINE; MALE; MIDDLE AGED; MULTIFIDUS MUSCLE; NUCLEAR MAGNETIC RESONANCE IMAGING; PARASPINAL MUSCLE; PHYSICAL INACTIVITY; QUESTIONNAIRE; RISK FACTOR; STATISTICAL ANALYSIS; ADIPOSE TISSUE; AGE; CHRONIC PAIN; COHORT ANALYSIS; COMPARATIVE STUDY; FOLLOW UP; LUMBAR VERTEBRA; MULTIVARIATE ANALYSIS; NORMAL HUMAN; PATHOLOGY; RISK ASSESSMENT; SEDENTARY LIFESTYLE; SEX DIFFERENCE; STATISTICAL MODEL;

ADIPOSE TISSUE; ADULT; AGE FACTORS; BODY MASS INDEX; CHRONIC PAIN; COHORT STUDIES; DISABILITY EVALUATION; FEMALE; FOLLOW-UP STUDIES; HEALTHY VOLUNTEERS; HUMANS; INTERVERTEBRAL DISC; LINEAR MODELS; LOW BACK PAIN; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PARASPINAL MUSCLES; RISK ASSESSMENT; SEDENTARY LIFESTYLE; SEX FACTORS; SURVEYS AND QUESTIONNAIRES;

EID: 84928800412     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-015-0629-y     Document Type: Article

References (34)

1. Hoy D, March L, Brooks P, Blyth F, Woolf A, Bain C, et al. The global burden of low back pain: estimates from the Global Burden of Disease 2010 study. Ann Rheum Dis. 2014;73:968-74. doi:10.1136/annrheumdis-2013-204428. Epub 2014 Mar 24.
2. Holth HS, Werpen HK, Zwart JA, Hagen K. Physical inactivity is associated with chronic musculoskeletal complaints 11 years later: results from the Nord-Trondelag Health Study. BMC Musculoskelet Disord. 2008;9:159. doi:10.1186/471-2474-9-159.
3. Chen SM, Liu MF, Cook J, Bass S, Lo SK. Sedentary lifestyle as a risk factor for low back pain: a systematic review. Int Arch Occup Environ Health. 2009;82:797-806. doi:10.1007/s00420-009-0410-0. Epub 2009 Mar 20.
4. Sitthipornvorakul E, Janwantanakul P, Purepong N, Pensri P, van der Beek AJ. The association between physical activity and neck and low back pain: a systematic review. Eur Spine J. 2011;20:677-89. doi:10.1007/s00586-010-1630-4. Epub 2010 Nov 27.
5. Sjolie AN. Persistence and change in nonspecific low back pain among adolescents: a 3-year prospective study. Spine (Phila Pa 1976). 2004;29:2452-7.
6. Holguin N, Uzer G, Chiang FP, Rubin C, Judex S. Brief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner. J Appl Physiol (1985). 2011;111:1846-53. doi:10.152/japplphysiol.00846.2011. Epub 2011 Sep 29.
7. Wuertz K, Godburn K, MacLean JJ, Barbir A, Donnelly JS, Roughley PJ, et al. In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression. J Orthop Res. 2009;27:1235-42. doi:10.002/jor.20867.
8. Castro MJ, Apple Jr DF, Hillegass EA, Dudley GA. Influence of complete spinal cord injury on skeletal muscle cross-sectional area within the first 6 months of injury. Eur J Appl Physiol Occup Physiol. 1999;80:373-8.
9. Kjaer P, Bendix T, Sorensen JS, Korsholm L, Leboeuf-Yde C. Are MRI-defined fat infiltrations in the multifidus muscles associated with low back pain? BMC Med. 2007;5:2.
10. Mengiardi B, Schmid MR, Boos N, Pfirrmann CW, Brunner F, Elfering A, et al. Fat content of lumbar paraspinal muscles in patients with chronic low back pain and in asymptomatic volunteers: quantification with MR spectroscopy. Radiology. 2006;240:786-92.
11. Urquhart DM, Kurniadi I, Triangto K, Wang Y, Wluka AE, O'Sullivan R, et al. Obesity is associated with reduced disc height in the lumbar spine but not at the lumbosacral junction. Spine (Phila Pa 1976). 2014;39:E962-6.
12. Giles GG, English DR. The Melbourne collaborative cohort study. IARC Sci Publ. 2002;156:69-70.
13. Hanna F, Teichtahl AJ, Bell RJ, Davis SR, Wluka AE, O'Sullivan R, et al. The cross-sectional relationship between fortnightly exercise and knee cartilage properties in healthy adult women in midlife. Menopause. 2007;14:830-4.
14. Richardson MT, Ainsworth BE, Jacobs DR, Leon AS. Validation of the Stanford 7-day recall to assess habitual physical activity. Ann Epidemiol. 2001;11:145-53.
15. Kader DF, Wardlaw D, Smith FW. Correlation between the MRI changes in the lumbar multifidus muscles and leg pain. Clin Radiol. 2000;55:145-9.
16. Von Korff M, Ormel J, Keefe FJ, Dworkin SF. Grading the severity of chronic pain. Pain. 1992;50:133-49.
17. Smith BH, Penny KI, Purves AM, Munro C, Wilson B, Grimshaw J, et al. The chronic pain grade questionnaire: validation and reliability in postal research. Pain. 1997;71:141-7.
18. Livshits G, Popham M, Malkin I, Sambrook PN, Macgregor AJ, Spector T, et al. Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study. Ann Rheum Dis. 2011;70:1740-5. doi:10.136/ard.2010.137836. Epub 2011 Jun 6.
19. Kettler A, Wilke HJ. Review of existing grading systems for cervical or lumbar disc and facet joint degeneration. Eur Spine J. 2006;15:705-18. Epub 2005 Sep 20.
20. Pfirrmann CW, Metzdorf A, Zanetti M, Hodler J, Boos N. Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976). 2001;26:1873-8.
21. D'Hooge R, Cagnie B, Crombez G, Vanderstraeten G, Dolphens M, Danneels L. Increased intramuscular fatty infiltration without differences in lumbar muscle cross-sectional area during remission of unilateral recurrent low back pain. Man Ther. 2012;17:584-8. doi:10.1016/j.math.2012.06.007. Epub 2012 Jul 10.
22. Rossi A, Zoico E, Goodpaster BH, Sepe A, Di Francesco V, Fantin F, et al. Quantification of intermuscular adipose tissue in the erector spinae muscle by MRI: agreement with histological evaluation. Obesity (Silver Spring). 2010;18:2379-84. doi:10.1038/oby.2010.48. Epub 2010 Mar 18.
23. Mitsiopoulos N, Baumgartner RN, Heymsfield SB, Lyons W, Gallagher D, Ross R. Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography. J Appl Physiol (1985). 1998;85:115-22.
24. Phoenix J, Betal D, Roberts N, Helliwell TR, Edwards RH. Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis. Muscle Nerve. 1996;19:302-10.
25. Brown WJ, Mishra G, Lee C, Bauman A. Leisure time physical activity in Australian women: relationship with well being and symptoms. Res Q Exerc Sport. 2000;71:206-16.
26. Bjorck-van Dijken C, Fjellman-Wiklund A, Hildingsson C. Low back pain, lifestyle factors and physical activity: a population based-study. J Rehabil Med. 2008;40:864-9. doi:10.2340/16501977-0273.
27. Heneweer H, Vanhees L, Picavet HS. Physical activity and low back pain: a U-shaped relation? Pain. 2009;143:21-5. doi:10.1016/j.pain.2008.12.033. Epub 2009 Feb 12.
28. Wedderkopp N, Kjaer P, Hestbaek L, Korsholm L, Leboeuf-Yde C. High-level physical activity in childhood seems to protect against low back pain in early adolescence. Spine J. 2009;9:134-41. doi:10.1016/j.spinee.2008.02.003. Epub 2008 May 20.
29. Auvinen J, Tammelin T, Taimela S, Zitting P, Karppinen J. Associations of physical activity and inactivity with low back pain in adolescents. Scand J Med Sci Sports. 2008;18:188-94. Epub 2007 May 9.
30. Diepenmaat AC, van der Wal MF, de Vet HC, Hirasing RA. Neck/shoulder, low back, and arm pain in relation to computer use, physical activity, stress, and depression among Dutch adolescents. Pediatrics. 2006;117:412-6.
31. Kujala UM, Taimela S, Viljanen T. Leisure physical activity and various pain symptoms among adolescents. Br J Sports Med. 1999;33:325-8.
32. Sjolie AN. Associations between activities and low back pain in adolescents. Scand J Med Sci Sports. 2004;14:352-9.
33. Mikkelsson LO, Nupponen H, Kaprio J, Kautiainen H, Mikkelsson M, Kujala UM. Adolescent flexibility, endurance strength, and physical activity as predictors of adult tension neck, low back pain, and knee injury: a 25 year follow up study. Br J Sports Med. 2006;40:107-13.
34. Parkkola R, Rytokoski U, Kormano M. Magnetic resonance imaging of the discs and trunk muscles in patients with chronic low back pain and healthy control subjects. Spine (Phila Pa 1976). 1993;18:830-6.