Host attachment and fluid shear are integrated into a mechanical signal regulating virulence in Escherichia coli O157:H7

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 17, 2015, Pages 5503-5508

  Alsharif, Ghadah ^a   Ahmad, Sadia ^a   Islam, Md Shahidul ^a,b   Shah, Riddhi ^a   Busby, Stephen J ^a   Krachler, Anne Marie ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BANGLADESH AGRICULTURAL UNIVERSITY   (Bangladesh)

Author keywords

Attaching effacing pathogens; Enterohemorrhagic Escherichia coli; Gastrointestinal infection; Locus of enterocyte effacement; Mechanosensing

Indexed keywords

ACTIN; INTIMIN; SHIGA TOXIN; ESCHERICHIA COLI PROTEIN; LEE PROTEIN, E COLI; LER PROTEIN, E COLI; PHOSPHOPROTEIN; TRANSACTIVATOR PROTEIN;

ACTIN POLYMERIZATION; ARTICLE; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CACO 2 CELL LINE; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; DELETION MUTANT; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ENZYME INHIBITION; ESCHERICHIA COLI K 12; ESCHERICHIA COLI O157; FEMALE; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GROWTH RATE; HELA CELL LINE; HOST CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INTESTINE CELL; NONHUMAN; PHENOTYPE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STATIC ELECTRICITY; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; MECHANOTRANSDUCTION; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; SHEAR STRENGTH;

ESCHERICHIA COLI;

BACTERIAL ADHESION; ENTEROCYTES; ESCHERICHIA COLI O157; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; HELA CELLS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; PHOSPHOPROTEINS; SHEAR STRENGTH; TRANS-ACTIVATORS;

EID: 84928789234     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1422986112     Document Type: Article

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