Obesity increases precision errors in total body dual-energy x-ray absorptiometry measurements

Journal of Clinical Densitometry

Volumn 18, Issue 2, 2015, Pages 209-216

  Knapp, Karen M ^a   Welsman, Joanne R ^a   Hopkins, Susan J ^a   Shallcross, Andrew ^a   Fogelman, Ignac ^b   Blake, Glen M ^b  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Bone mineral density; Dual energy X ray absorptiometry; Obesity; Precision

Indexed keywords

ADIPOSE TISSUE; ADULT; ANALYTICAL ERROR; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; BONE DENSITY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; OBESITY; PRIORITY JOURNAL; X RAY BONE DENSITOMETER; ADOLESCENT; AGED; BONE; CASE CONTROL STUDY; MIDDLE AGED; PHOTON ABSORPTIOMETRY; RADIOGRAPHY; REPRODUCIBILITY; YOUNG ADULT;

ABSORPTIOMETRY, PHOTON; ADIPOSE TISSUE; ADOLESCENT; ADULT; AGED; BODY MASS INDEX; BONE AND BONES; BONE DENSITY; CASE-CONTROL STUDIES; FEMALE; HUMANS; MIDDLE AGED; OBESITY; OVERWEIGHT; REPRODUCIBILITY OF RESULTS; YOUNG ADULT;

EID: 84928769832     PISSN: 10946950     EISSN: 15590747     Source Type: Journal    
DOI: 10.1016/j.jocd.2014.06.001     Document Type: Article

References (23)

1. Bandirali M., Lanza E., Messina C., et al. Dose absorption in lumbar and femoral dual energy X-ray absorptiometry examinations using three different scan modalities: an anthropomorphic phantom study. J Clin Densitom 2013, 16(3):279-282.
2. Blake G.M., Naeem M., Boutros M. Comparison of effective dose to children and adults from dual X-ray absorptiometry examinations. Bone 2006, 38(6):935-942.
3. Engelke K., Gluer C.C. Quality and performance measures in bone densitometry: part 1: errors and diagnosis. Osteoporos Int 2006, 17(9):1283-1292.
4. Albanese C.V., Diessel E., Genant H.K. Clinical applications of body composition measurements using DXA. J Clin Densitom 2003, 6(2):75-85.
5. Buehring B., Krueger D., Libber J., et al. Dual-energy X-ray absorptiometry measured regional body composition least significant change: effect of region of interest and gender in athletes. J Clin Densitom 2014, 17(1):121-128.
6. Shepherd J.A., Lu Y., Wilson K., et al. Cross-calibration and minimum precision standards for dual-energy x-ray absorptiometry: the 2005 ISCD Official Positions. J Clin Densitom 2006, 9(1):31-36.
7. Hans D.B., Shepherd J.A., Schwartz E.N., et al. Peripheral dual-energy X-ray absorptiometry in the management of osteoporosis: the 2007 ISCD Official Positions. J Clin Densitom 2008, 11(1):188-206.
8. Gluer C.C., Blake G., Lu Y., et al. Accurate assessment of precision errors-how to measure the reproducibility of bone densitometry techniques. Osteoporos Int 1995, 5(4):262-270.
9. Cordero-MacIntyre Z.R., Peters W., Libanati C.R., et al. Reproducibility of DXA in obese women. J Clin Densitom 2002, 5(1):35-44.
10. Knapp K.M., Welsman J.R., Hopkins S.J., et al. Obesity increases precision errors in dual-energy x-ray absorptiometry measurements. J Clin Densitom 2012, 15(3):315-319.
11. NHS. Health survey for England 2009: health and lifestyles, Vol. 1. The Information Centre for health and social care. Available from: [Accessed July 16, 2014]. http://www.hscic.gov.uk/catalogue/PUB00414/heal-surv-heal-life-eng-2009-rep-v2.pdf.
12. Zaninotto P., Head J., Stamatakis E., et al. Trends in obesity among adults in England from 1993 to 2004 by age and social class and projections of prevalence to 2012. J Epidemiol Community Health 2009, 63(2):140-146.
13. Physical status: The Use and Interpretation of Anthropometry. Report of a WHO Expert Committee. WHO Technical Report Series 854 1995, World Health Organization, World Health Organization, Geneva, Switzerland.
14. Shepherd J.A., Lu Y. A generalized least significant change for individuals measured on different DXA systems. J Clin Densitom 2007, 10(3):249-258.
15. Kiebzak G.M., Leamy L.J., Pierson L.M., et al. Measurement precision of body composition variables using the lunar DPX-L densitometer. J Clin Densitom 2000, 3(1):35-41.
16. Reid EJ, Kilsby H, West H, etal. 2011 Is body mass index a good measure of body fatness? UK Radiological Congress, BIR UKRC conference proceedings, Manchester, UK, June 6-8, 2011, p15.
17. Howel D. Trends in the prevalence of obesity and overweight in English adults by age and birth cohort, 1991-2006. Public Health Nutr 2011, 14(1):27-33.
18. Baim S., Binkley N., Bilezikian J.R., et al. Official positions of the International Society for Clinical Densitometry and executive summary of the 2007 ISCD Position Development Conference. J Clin Densitom 2008, 11(1):75-91.
19. Bertin E., Marcus C., Ruiz J.C., et al. Measurement of visceral adipose tissue by DXA combined with anthropometry in obese humans. Int J Obes 2000, 24(3):263-270.
20. Binkley N., Krueger D., Vallarta-Ast N. An overlying fat panniculus affects femur bone mass measurement. J Clin Densitom 2003, 6(3):199-204.
21. Patel R., Blake G.M., Rymer J., Fogelman I. Long-term precision of DXA scanning assessed over seven years in forty postmenopausal women. Osteoporos Int 2000, 11(1):68-75.
22. Rajamanohara R., Robinson J., Rymer J., et al. The effect of weight and weight change on the long-term precision of spine and hip DXA measurements. Osteoporos Int 2011, 22(5):1503-1512.
23. Leslie W.D. Factors affecting short-term bone density precision assessment and the effect on patient monitoring. J Bone Miner Res 2008, 23(2):199-204.