The effect of cyclodextrins on the aqueous solubility of a new MMP inhibitor: phase solubility, 1 H-NMR spectroscopy and molecular modeling studies, preparation and stability study of nebulizable solutions

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques

Volumn 8, Issue 2, 2005, Pages 163-174

  Bertholet, Pascal ^a   Gueders, Maud ^a   Dive, Georges ^a   Albert, Adelin ^a   Barillaro, Valery ^a   Perly, Bruno ^a   Cataldo, Didier ^a   Piel, Géraldine ^a   Delattre, Luc ^a   Evrard, Brigitte ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLODEXTRIN; MATRIX METALLOPROTEINASE INHIBITOR; PIPERAZINE DERIVATIVE; PROTEINASE INHIBITOR; PROTON; PYRIMIDINE DERIVATIVE; RO 28-2653; SOLUTION AND SOLUBILITY; WATER;

ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; DRUG STABILITY; NEBULIZER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; SOLUBILITY; SOLUTION AND SOLUBILITY;

CYCLODEXTRINS; DRUG STABILITY; MAGNETIC RESONANCE SPECTROSCOPY; MATRIX METALLOPROTEINASE INHIBITORS; MODELS, MOLECULAR; NEBULIZERS AND VAPORIZERS; PHARMACEUTICAL SOLUTIONS; PIPERAZINES; PROTEASE INHIBITORS; PROTONS; PYRIMIDINES; SOLUBILITY; WATER;

EID: 84928768106     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: None     Document Type: Article

References (0)