Role of the D3 dopamine receptor in nicotine sensitization

Behavioural Brain Research

Volumn 289, Issue , 2015, Pages 92-104

  Smith, Laura N ^a   Bachus, Susan E ^a   McDonald, Craig G ^a   Smith, Robert F ^a  

^a GEORGE MASON UNIVERSITY   (United States)

Author keywords

Adolescence; D3 receptor antagonist; D3nf splice variant; Dopamine receptor; Nicotine; Sensitization

Indexed keywords

D3NF PROTEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR; MESSENGER RNA; NICOTINE; PROTEIN VARIANT; UNCLASSIFIED DRUG; 4' ACETYL N [4 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]BUTYL]BIPHENYL 4 CARBOXAMIDE; BIPHENYL DERIVATIVE; PIPERAZINE DERIVATIVE;

ADOLESCENT; ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SENSITIZATION; SIGNAL TRANSDUCTION; TOBACCO DEPENDENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; CENTRAL NERVOUS SYSTEM SENSITIZATION; CORPUS STRIATUM; DRUG EFFECTS; GENETICS; LONG EVANS RAT; METABOLISM; MOTOR ACTIVITY;

ANIMALS; BIPHENYL COMPOUNDS; CENTRAL NERVOUS SYSTEM SENSITIZATION; CORPUS STRIATUM; MALE; MOTOR ACTIVITY; NICOTINE; PIPERAZINES; RATS; RATS, LONG-EVANS; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D3; RNA, MESSENGER;

EID: 84928752225     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2015.04.025     Document Type: Article

References (53)

1. Substance Abuse and Mental Health Services Administration Results from the 2013 National Survey on Drug Use and Health 2014, samhsa.gov, Rockville, MD.
2. National Center for Chronic Disease Prevention and Health Promotion (US) Office on Smoking and Health Preventing tobacco use among youth and young adults: a report of the surgeon general 2012, Centers for Disease Control and Prevention (US), Atlanta, GA.
3. Breslau N., Peterson E.L. Smoking cessation in young adults: age at initiation of cigarette smoking and other suspected influences. Am J Public Health 1996, 86:214-220.
4. McWhorter W.P., Boyd G.M., Mattson M.E. Predictors of quitting smoking: the NHANES I followup experience. J Clin Epidemiol 1990, 43:1399-1405.
5. Novak G., LeBlanc M., Zai C., Shaikh S., Renou J., DeLuca V., et al. Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia. Ann Hum Genet 2010, 74:291-298. 10.1111/j.1469-1809.2010.00578.x.
6. Mansour A., Meador-Woodruff J.H., Bunzow J.R., Civelli O., Akil H., Watson S.J. Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis. J Neurosci 1990, 10:2587-2600.
7. Bouthenet M.L., Souil E., Martres M.P., Sokoloff P., Giros B., Schwartz J.C. Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA. Brain Res 1991, 564:203-219.
8. Le Moine C., Bloch B. Expression of the D3 dopamine receptor in peptidergic neurons of the nucleus accumbens: comparison with the D1 and D2 dopamine receptors. Neuroscience 1996, 73:131-143.
9. Sokoloff P., Giros B., Martres M.P., Bouthenet M.L., Schwartz J.C. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature 1990, 347:146-151. 10.1038/347146a0.
10. Sales N., Martres M.P., Bouthenet M.L., Schwartz J.C. Ontogeny of dopaminergic D-2 receptors in the rat nervous system: characterization and detailed autoradiographic mapping with [125I]iodosulpride. Neuroscience 1989, 28:673-700.
11. Schambra U.B., Duncan G.E., Breese G.R., Fornaretto M.G., Caron M.G., Fremeau R.T. Ontogeny of D1A and D2 dopamine receptor subtypes in rat brain using in situ hybridization and receptor binding. Neuroscience 1994, 62:65-85.
12. Gurevich E.V., Himes J.W., Joyce J.N. Developmental regulation of expression of the D3 dopamine receptor in rat nucleus accumbens and islands of Calleja. J Pharmacol Exp Ther 1999, 289:587-598.
13. Stanwood G.D., McElligot S., Lu L., McGonigle P. Ontogeny of dopamine D3 receptors in the nucleus accumbens of the rat. Neurosci Lett 1997, 223:13-16.
14. Smith R.F. Animal models of periadolescent substance abuse. Neurotoxicol Teratol 2003, 25:291-301.
15. Sato M., Chen C.C., Akiyama K., Otsuki S. Acute exacerbation of paranoid psychotic state after long-term abstinence in patients with previous methamphetamine psychosis. BPS 1983, 18:429-440.
16. Paulson P.E., Camp D.M., Robinson T.E. Time course of transient behavioral depression and persistent behavioral sensitization in relation to regional brain monoamine concentrations during amphetamine withdrawal in rats. Psychopharmacology (Berl) 1991, 103:480-492.
17. Elmhurst J.L., Xie Z., O'Dowd B.F., George S.R. The splice variant D3nf reduces ligand binding to the D3 dopamine receptor: evidence for heterooligomerization. Brain Res Mol Brain Res 2000, 80:63-74.
18. Karpa K.D., Lin R., Kabbani N., Levenson R. The dopamine D3 receptor interacts with itself and the truncated D3 splice variant d3nf: D3-D3nf interaction causes mislocalization of D3 receptors. Mol Pharmacol 2000, 58:677-683.
19. Richtand N.M. Behavioral sensitization, alternative splicing, and d3 dopamine receptor-mediated inhibitory function. Neuropsychopharmacology 2006, 31:2368-2375. 10.1038/sj.npp.1301163.
20. Richtand N.M., Woods S.C., Berger S.P., Strakowski S.M. D3 dopamine receptor, behavioral sensitization, and psychosis. Neurosci Biobehav Rev 2001, 25:427-443.
21. Derouiche A., Asan E. The dopamine D2 receptor subfamily in rat retina: ultrastructural immunogold and in situ hybridization studies. Eur J Neurosci 1999, 11:1391-1402.
22. Giros B., Martres M.P., Pilon C., Sokoloff P., Schwartz J.C. Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing. Biochem Biophys Res Commun 1991, 176:1584-1592.
23. Pagliusi S., Chollet-Daemerius A., Losberger C., Mills A., Kawashima E. Characterization of a novel exon within the D3 receptor gene giving rise to an mRNA isoform expressed in rat brain. Biochem Biophys Res Commun 1993, 194:465-471.
24. Pritchard L.M., Logue A.D., Taylor B.C., Ahlbrand R., Welge J.A., Tang Y., et al. Relative expression of D3 dopamine receptor and alternative splice variant D3nf mRNA in high and low responders to novelty. Brain Res Bull 2006, 70:296-303. 10.1016/j.brainresbull.2006.06.010.
25. Schmauss C., Haroutunian V., Davis K.L., Davidson M. Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia. Proc Natl Acad Sci U S A 1993, 90:8942-8946.
26. Snyder L.A., Roberts J.L., Sealfon S.C. Alternative transcripts of the rat and human dopamine D3 receptor. Biochem Biophys Res Commun 1991, 180:1031-1035.
27. Nagai Y., Ueno S., Saeki Y., Soga F., Yanagihara T. Expression of the D3 dopamine receptor gene and a novel variant transcript generated by alternative splicing in human peripheral blood lymphocytes. Biochem Biophys Res Commun 1993, 194:368-374. 10.1006/bbrc.1993.1829.
28. Claye L.H., Akunne H.C., Davis M.D., DeMattos S., Soliman K.F. Behavioral and neurochemical changes in the dopaminergic system after repeated cocaine administration. Mol Neurobiol 1995, 11:55-66.
29. Kirch D.G., Taylor T.R., Creese I., Xu S.X., Wyatt R.J. Effect of chronic nicotine treatment and withdrawal on rat striatal D1 and D2 dopamine receptors. J Pharm Pharmacol 1992, 44:89-92.
30. Kunko P.M., French D., Izenwasser S. Alterations in locomotor activity during chronic cocaine administration: effect on dopamine receptors and interaction with opioids. J Pharmacol Exp Ther 1998, 285:277-284.
31. Le Foll B., Diaz J., Sokoloff P. Increased dopamine D3 receptor expression accompanying behavioral sensitization to nicotine in rats. Synapse 2003, 47:176-183. 10.1002/syn.10170.
32. Fung Y.K., Lau Y.S. Receptor mechanisms of nicotine-induced locomotor hyperactivity in chronic nicotine-treated rats. Eur J Pharmacol 1988, 152:263-271.
33. Wiener H.L., Lajtha A., Sershen H. Dopamine D1 receptor and dopamine D2 receptor binding activity changes during chronic administration of nicotine in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice. Neuropharmacology 1989, 28:535-537.
34. Levin E.D., Lawrence S.S., Petro A., Horton K., Rezvani A.H., Seidler F.J., et al. Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates. Neurotoxicol Teratol 2007, 29:458-465. 10.1016/j.ntt.2007.02.002.
35. Levin E.D., Rezvani A.H., Montoya D., Rose J.E., Swartzwelder H.S. Adolescent-onset nicotine self-administration modeled in female rats. Psychopharmacologia 2003, 169:141-149. 10.1007/s00213-003-1486-y.
36. Belluzzi J.D., Lee A.G., Oliff H.S., Leslie F.M. Age-dependent effects of nicotine on locomotor activity and conditioned place preference in rats. Psychopharmacologia 2004, 174:389-395. 10.1007/s00213-003-1758-6.
37. Brielmaier J.M., McDonald C.G., Smith R.F. Immediate and long-term behavioral effects of a single nicotine injection in adolescent and adult rats. Neurotoxicol Teratol 2007, 29:74-80. 10.1016/j.ntt.2006.09.023.
38. Vastola B.J., Douglas L.A., Varlinskaya E.I., Spear L.P. Nicotine-induced conditioned place preference in adolescent and adult rats. Physiol Behav 2002, 77:107-114.
39. Campbell J.O., Wood R.D., Spear L.P. Cocaine and morphine-induced place conditioning in adolescent and adult rats. Physiol Behav 2000, 68:487-493.
40. Acquas E., Carboni E., Leone P., Di Chiara G. SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade?. Psychopharmacologia 1989, 99:151-155. 10.1007/BF00442800.
41. Medvedev I.O., Ramsey A.J., Masoud S.T., Bermejo M.K., Urs N., Sotnikova T.D., et al. D1 dopamine receptor coupling to PLC regulates forward locomotion in mice. J Neurosci 2013, 33:18125-18133. 10.1523/JNEUROSCI.2382-13.2013.
42. Swanson C.J., Heath S., Stratford T.R., Kelley A.E. Differential behavioral responses to dopaminergic stimulation of nucleus accumbens subregions in the rat. Pharmacol Biochem Behav 1997, 58:933-945. 10.1016/S0091-3057(97)00043-9.
43. Varlinskaya E.I., Truxell E.M., Spear L.P. Repeated restraint stress alters sensitivity to the social consequences of ethanol differentially in early and late adolescent rats. Pharmacol Biochem Behav 2013, 113:38-45. 10.1016/j.pbb.2013.10.016.
44. Zurawek D., Faron-Górecka A., Kuśmider M., Kolasa M., Gruca P., Papp M., et al. Mesolimbic dopamine D2 receptor plasticity contributes to stress resilience in rats subjected to chronic mild stress. Psychopharmacology (Berl) 2013, 227:583-593. 10.1007/s00213-013-2990-3.
45. Wheeler T.L., Smith L.N., Bachus S.E., McDonald C.G., Fryxell K.J., Smith R.F. Low-dose adolescent nicotine and methylphenidate have additive effects on adult behavior and neurochemistry. Pharmacol Biochem Behav 2013, 103:723-734. 10.1016/j.pbb.2012.12.005.
46. Spyraki C., Sealfon S.C. Regulation of dopamine D2 receptor mRNA expression in the olfactory tubercle by cocaine. Brain Res Mol Brain Res 1993, 19:313-317.
47. de Araujo N.P., Fukushiro D.F., Grassl C., Hipolide D.C., Souza-Formigoni M.L.O., Tufik S., et al. Ethanol-induced behavioral sensitization is associated with dopamine receptor changes in the mouse olfactory tubercle. Physiol Behav 2009, 96:12-17. 10.1016/j.physbeh.2008.07.029.
48. Murray J.P., Harrison L.A., Johnson M.R., Robertson G.M., Scopes D.I.C., Bull D.R., et al. A novel series of arylpiperazines with high affinity and selectivity for the dopamine D3 receptor. Bioorg Med Chem Lett 1995, 5:219-222.
49. Clifford J.J., Waddington J.L. Heterogeneity of behavioural profile between three new putative selective D3 dopamine receptor antagonists using an ethologically based approach. Psychopharmacology (Berl) 1998, 136:284-290.
50. Stuchlik A., Rehakova L., Rambousek L., Svoboda J., Vales K. Manipulation of D2 receptors with quinpirole and sulpiride affects locomotor activity before spatial behavior of rats in an active place avoidance task. Neurosci Res 2007, 58:133-139. 10.1016/j.neures.2007.02.006.
51. Waters N., Svensson K., Haadsma-Svensson S.R., Smith M.W., Carlsson A. The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity. J Neural Transm Gen Sect 1993, 94:11-19.
52. Harrison S.J., Nobrega J.N. A functional role for the dopamine D3 receptor in the induction and expression of behavioural sensitization to ethanol in mice. Psychopharmacology (Berl) 2009, 207:47-56. 10.1007/s00213-009-1629-x.
53. Young W.S. In Situ Hybridization with Oligodeoxyribonucleotide Probes 1992, 33-44. Chapter 3, Oxford University Press, New York. D.G. Wilkinson (Ed.).