Effects of an oral nutritional supplementation plus physical exercise intervention on the physical function, nutritional status, and quality of life in frail institutionalized older adults: The ACTIVNES study

Journal of the American Medical Directors Association

Volumn 16, Issue 5, 2015, Pages 439.e9-439.e16

  Abizanda, Pedro ^a   López, Mateo Díez ^b   García, Victoria Pérez ^c   Estrella, Juan de Dios ^a   da Silva González, Álvaro ^d   Vilardell, Núria Barcons ^e   Torres, Krysmarú Araujo ^e  

^a HOSPITAL GENERAL UNIVERSITARIO DE ALBACETE   (Spain)

^b Centro Residencial Jardin de Tardajos   (Spain)

^c AUTONOMOUS UNIVERSITY OF MADRID   (Spain)

^d Residencia de Ancianos de la Diputación Provincial de Burgos   (Spain)

^e I3 Research   (Spain)

Author keywords

Frail elderly; Function; Nursing homes; Nutrition enteral; Physical exercise

Indexed keywords

CALCIUM; PREBIOTIC AGENT; VITAMIN D; VITAMIN;

AGED; ARTICLE; BODY MASS; DIETARY FIBER; EUROQOL 5 DIMENSIONS VISUAL ANALOG SCALE; EXERCISE; FEMALE; FRAIL ELDERLY; FUNCTIONAL ASSESSMENT; GRIP STRENGTH; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY (TOPIC); MUSCLE STRENGTH; NUTRITIONAL STATUS; NUTRITIONAL SUPPORT; PHYSICAL PERFORMANCE; QUALITY OF LIFE; QUALITY OF LIFE ASSESSMENT; RATING SCALE; SCORING SYSTEM; SHORT FORM LATE LIFE FUNCTION AND DISABITLITY INSTRUMENT; SHORT FORM MINI NUTRITIONAL ASSESSMENT; SHORT PHYSICAL PERFORMANCE BATTERY; SPAIN; VERY ELDERLY; VISUAL ANALOG SCALE; WEIGHT GAIN; CLINICAL TRIAL; DAILY LIFE ACTIVITY; DIETARY SUPPLEMENT; MULTICENTER STUDY; NURSING HOME; PROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; DIETARY SUPPLEMENTS; EXERCISE; FEMALE; FRAIL ELDERLY; HUMANS; MALE; NURSING HOMES; NUTRITIONAL STATUS; PROSPECTIVE STUDIES; QUALITY OF LIFE; TREATMENT OUTCOME; VITAMINS;

EID: 84928699865     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2015.02.005     Document Type: Article

References (42)

1. Morley J.E., Vellas B., van Kan G.A., et al. Frailty consensus: A call to action. JAm Med Dir Assoc 2013, 14:392-397.
2. Rodríguez-Mañas L., Féart C., Mann G., et al. Searching for an operational definition of frailty: A Delphi method based consensus statement. The Frailty Operative Definition-Consensus Conference Project. JGerontol A Biol Sci Med Sci 2013, 68:62-67.
3. Collard R.M., Boter H., Schoevers R.A., Oude Voshaar R.C. Prevalence of frailty in community-dwelling older persons: A systematic review. JAm Geriatr Soc 2012, 60:1487-1492.
4. Freiheit E.A., Hogan D.B., Strain L.A., et al. Operationalizing frailty among older residents of assisted living facilities. BMC Geriatr 2011, 11:23.
5. Rockwood K., Abeysundera M.J., Mitnitski A. How should we grade frailty in nursing home patients?. JAm Med Dir Assoc 2007, 8:595-603.
6. Matusik P., Tomaszewski K., Chmielowska K., et al. Severe frailty and cognitive impairment are related to higher mortality in 12-month follow-up of nursing home residents. Arch Gerontol Geriatr 2012, 55:22-24.
7. Garrido M., Serrano M.D., Bartolomé R., Martínez-Vizcaíno V. Differences in the expression of the frailty syndrome in institutionalized elderly men and women with no severe cognitive decline. Rev Esp Geriatr Gerontol 2012, 47:247-253.
8. González-Vaca J., de la Rica-Escuín M., Silva-Iglesias M., et al. Frailty in INstitutionalized older adults from ALbacete. The FINAL Study: Rationale, design, methodology, prevalence and attributes. Maturitas 2014, 77:78-84.
9. Shamliyan T., Talley K.M., Ramakrishnan R., Kane R.L. Association of frailty with survival: A systematic literature review. Ageing Res Rev 2013, 12:719-736.
10. Abizanda P., Romero L., Sánchez-Jurado P.M., et al. Frailty and mortality, disability and mobility loss in a Spanish cohort of older adults: The FRADEA study. Maturitas 2013, 74:54-60.
11. Romero Rizos L., Abizanda Soler P. Frailty as a predictor of adverse events in epidemiological studies: Literature review. Rev Esp Geriatr Gerontol 2013, 48:285-289.
12. Hogan D.B., Freiheit E.A., Strain L.A., et al. Comparing frailty measures in their ability to predict adverse outcome among older residents of assisted living. BMC Geriatr 2012, 12:56.
13. de la Rica-Escuín M., González-Vaca J., Varela-Pérez R., et al. Frailty and mortality or incident disability in institutionalized older adults: The FINAL study. Maturitas 2014, 78:329-334.
14. Volkert D., Berner Y.N., Berry E., et al. ESPEN Guidelines on enteral nutrition: Geriatrics. Clin Nutr 2006, 25:330-360.
15. Cadore E.L., Rodríguez-Mañas L., Sinclair A., Izquierdo M. Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: A systematic review. Rejuvenation Res 2013, 16:105-114.
16. Izquierdo M., Cadore E.L. Muscle power training in the institutionalized frail: A new approach to counteracting functional declines and very late-life disability. Curr Med Res Opin 2014, 30:1385-1390.
17. Weening-Dijksterhuis E., de Greef M.H., Scherder E.J., et al. Frail institutionalized older persons: A comprehensive review on physical exercise, physical fitness, activities of daily living, and quality-of-life. Am J Phys Med Rehabil 2011, 90:156-168.
18. Cameron I.D., Fairhall N., Langron C., et al. Amultifactorial interdisciplinary intervention reduces frailty in older people: Randomized trial. BMC Med 2013, 11:65.
19. Crocker T., Forster A., Young J., et al. Physical rehabilitation for older people in long-term care. Cochrane Database Syst Rev 2013, (2):CD004294.
20. Crocker T., Young J., Forster A., et al. The effect of physical rehabilitation on activities of daily living in older residents of long-term care facilities: Systematic review with meta-analysis. Age Ageing 2013, 42:682-688.
21. Grönstedt H., Frändin K., Bergland A., et al. Effects of individually tailored physical and daily activities in nursing home residents on activities of daily living, physical performance and physical activity level: A randomized controlled trial. Gerontology 2013, 59:220-229.
22. Tieland M., van de Rest O., Dirks M.L., et al. Protein supplementation improves physical performance in frail elderly people: A randomized, double-blind, placebo-controlled trial. JAm Med Dir Assoc 2012, 13:720-726.
23. Tieland M., Dirks M.L., van der Zwaluw N., et al. Protein supplementation increases muscle mass gain during prolonged resistance-type exercise training in frail elderly people: A randomized, double-blind, placebo-controlled trial. JAm Med Dir Assoc 2012, 13:713-719.
24. Samefors M., Östgren C.J., Mölstad S., et al. Vitamin D deficiency in elderly people in Swedish nursing homes is associated with increased mortality. Eur J Endocrinol 2014, 170:667-675.
25. Schöttker B., Ball D., Gellert C., Brenner H. Serum 25-hydroxyvitamin D levels and overall mortality. A systematic review and meta-analysis of prospective cohort studies. Ageing Res Rev 2013, 12:708-718.
26. Cameron I.D., Gillespie L.D., Robertson M.C., et al. Interventions for preventing falls in older people in care facilities and hospitals. Cochrane Database Syst Rev 2012, (12):CD005465.
27. Zak M., Swine C., Grodzicki T. Combined effects of functionally-oriented exercise regimens and nutritional supplementation on both the institutionalised and free-living frail elderly (double-blind, randomised clinical trial). BMC Public Health 2009, 9:39.
28. Fiatarone M.A., O'Neill E.F., Ryan N.D., et al. Exercise training and nutritional supplementation for physical frailty in very elderly people. NEngl J Med 1994, 330:1769-1775.
29. Guralnik J.M., Simonsick E.M., Ferrucci L., et al. Ashort physical performance battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. JGerontol 1994, 49:M85-M94.
30. Kwon S., Perera S., Pahor M., et al. What is a meaningful change in physical performance? Findings from a clinical trial in older adults (The LIFE-P Study). JNutr Health Aging 2009, 13:538-544.
31. Abizanda P., López-Jiménez M., López-Torres J., et al. Validation of the Spanish version of the short-form late-life function and disability instrument. JAm Geriatr Soc 2011, 59:893-899.
32. Chumbler N.R., Quigley P., Li X., et al. Effects of telerehabilitation on physical function and disability for stroke patients: A randomized, controlled trial. Stroke 2012, 43:2168-2174.
33. EuroQol, a new facility for the measurement of health related quality of life. Health Policy 1990, 16:199-208. The EuroQol Group.
34. Pérez Llamas F., Moregó A., Tóbaruela M., et al. Prevalence of malnutrition and influence of oral nutritional supplementation on nutritional status in institutionalized elderly. Nutr Hosp 2011, 26:1134-1140.
35. Rodríguez-Mañas L., Bayer A.J., Kelly M., et al. An evaluation of the effectiveness of a multi-modal intervention in frail and pre-frail older people with type 2 diabetes-the MID-Frail study: Study protocol for a randomised controlled trial. Trials 2014, 15:34.
36. Clegg A., Young J., Iliffe S., et al. Frailty in elderly people. Lancet 2013, 381:752-762.
37. Fairhall N., Langron C., Sherrington C., et al. Treating frailty-a practical guide. BMC Med 2011, 9:83.
38. Girgis C.M., Mokbel N., Cha K.M., et al. The vitamin D receptor (VDR) is expressed in skeletal muscle of male mice and modulates 25-hydroxyvitamin D (25OHD) uptake in myofibers. Endocrinology 2014, 155:3227-3237.
39. Ceglia L., Harris S.S. Vitamin D and its role in skeletal muscle. Calcif Tissue Int 2013, 92:151-162.
40. Freijer K., Bours M.J., Nuijten M.J., et al. The economic value of enteral medical nutrition in the management of disease-related malnutrition: A systematic review. JAm Med Dir Assoc 2014, 15:17-29.
41. Tamura B.K., Bell C.L., Masaki K.H., Amella E.J. Factors associated with weight loss, low BMI, and malnutrition among nursing home patients: A systematic review of the literature. JAm Med Dir Assoc 2013, 14:649-655.
42. Slaughter S.E., Wagg A.S., Jones C.A., et al. Mobility of vulnerable elders study: Effect of the sit-to-stand activity on mobility, function, and quality of life. JAm Med Dir Assoc 2015, 16:138-143.