SCOPUS 정보 검색 플랫폼

Angewandte Chemie - International Edition

Volumn 54, Issue 24, 2015, Pages 7022-7027

Multiformat T-Cell-engaging bispecific antibodies targeting human breast cancers

(17) Cao, Yu a Axup, Jun Y a Ma, Jennifer S Y b Wang, Rongsheng E a Choi, Seihyun a Tardif, Virginie a Lim, Reyna K V b Pugh, Holly M b Lawson, Brian R a Welzel, Gus b Kazane, Stephanie A b Sun, Ying c Tian, Feng c Srinagesh, Shailaja c Javahishvili, Tsotne c Schultz, Peter G a Kim, Chan Hyuk b

a SCRIPPS RESEARCH INSTITUTE (United States)

b California Institute for Biomedical Research (United States)

c AMBRX INC (United States)

Author keywords

antibody drug conjugates; bispecific antibodies; breast cancers; noncanonical amino acids; T cell activation

Indexed keywords

AMINO ACIDS; ANTIGENS; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; CYTOTOXICITY; DISEASES; T-CELLS;

ANTI-TUMOR EFFICACY; ANTIBODY-DRUG CONJUGATES; BREAST CANCER; BREAST CANCER CELLS; CYTOTOXIC ACTIVITIES; HUMAN BREAST CANCER; NON-CANONICAL AMINO ACIDS; T CELL ACTIVATION;

ANTIBODIES;

BISPECIFIC ANTIBODY; CD3 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN; FC RECEPTOR; TRASTUZUMAB;

ANIMAL; BREAST NEOPLASMS; CHEMISTRY; DRUG SCREENING; FEMALE; HUMAN; IMMUNOLOGY; JURKAT CELL LINE; METABOLISM; MONONUCLEAR CELL; MOUSE; PATHOLOGY; T LYMPHOCYTE; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTIGENS, CD3; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HUMANS; JURKAT CELLS; LEUKOCYTES, MONONUCLEAR; MICE; RECEPTOR, ERBB-2; RECEPTORS, FC; T-LYMPHOCYTES; TRASTUZUMAB; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84928693378 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201500799 Document Type: Article

Times cited : (35)

References (41)

1
- 0036467826
- C. L. Vogel, M. A. Cobleigh, D. Tripathy, J. C. Gutheil, L. N. Harris, L. Fehrenbacher, D. J. Slamon, M. Murphy, W. F. Novotny, M. Burchmore, S. Shak, S. J. Stewart, M. Press, J. Clin. Oncol. 2002, 20, 719-726.
- (2002) J. Clin. Oncol. , vol.20 , pp. 719-726
- Vogel, C.L.¹ Cobleigh, M.A.² Tripathy, D.³ Gutheil, J.C.⁴ Harris, L.N.⁵ Fehrenbacher, L.⁶ Slamon, D.J.⁷ Murphy, M.⁸ Novotny, W.F.⁹ Burchmore, M.¹⁰ Shak, S.¹¹ Stewart, S.J.¹² Press, M.¹³

2
- 84892168048
- I. Krop, E. P. Winer, Clin. Cancer Res. 2014, 20, 15-20.
- (2014) Clin. Cancer Res. , vol.20 , pp. 15-20
- Krop, I.¹ Winer, E.P.²

3
- 84856716249
- G. M. Keating, Drugs 2012, 72, 353-360.
- (2012) Drugs , vol.72 , pp. 353-360
- Keating, G.M.¹

4
- 3042622482
- M. A. Owens, B. C. Horten, M. M. Da Silva, Clin. Breast Cancer 2004, 5, 63-69.
- (2004) Clin. Breast Cancer , vol.5 , pp. 63-69
- Owens, M.A.¹ Horten, B.C.² Da Silva, M.M.³

5
- 56449129810
- G. D. Lewis Phillips, G. Li, D. L. Dugger, L. M. Crocker, K. L. Parsons, E. Mai, W. A. Blattler, J. M. Lambert, R. V. Chari, R. J. Lutz, W. L. Wong, F. S. Jacobson, H. Koeppen, R. H. Schwall, S. R. Kenkare-Mitra, S. D. Spencer, M. X. Sliwkowski, Cancer Res. 2008, 68, 9280-9290.
- (2008) Cancer Res. , vol.68 , pp. 9280-9290
- Lewis Phillips, G.D.¹ Li, G.² Dugger, D.L.³ Crocker, L.M.⁴ Parsons, K.L.⁵ Mai, E.⁶ Blattler, W.A.⁷ Lambert, J.M.⁸ Chari, R.V.⁹ Lutz, R.J.¹⁰ Wong, W.L.¹¹ Jacobson, F.S.¹² Koeppen, H.¹³ Schwall, R.H.¹⁴ Kenkare-Mitra, S.R.¹⁵ Spencer, S.D.¹⁶ Sliwkowski, M.X.¹⁷

6
- 77749239974
- D. Müller, R. E. Kontermann, BioDrugs 2010, 24, 89-98.
- (2010) BioDrugs , vol.24 , pp. 89-98
- Müller, D.¹ Kontermann, R.E.²

7
- 74949107560
- L. Ducry, B. Stump, Bioconjugate Chem. 2010, 21, 5-13.
- (2010) Bioconjugate Chem. , vol.21 , pp. 5-13
- Ducry, L.¹ Stump, B.²

8
- 66249126868
- M. Jager, A. Schoberth, P. Ruf, J. Hess, H. Lindhofer, Cancer Res. 2009, 69, 4270-4276.
- (2009) Cancer Res. , vol.69 , pp. 4270-4276
- Jager, M.¹ Schoberth, A.² Ruf, P.³ Hess, J.⁴ Lindhofer, H.⁵

9
- 84907494587
- T. T. Junttila, J. Li, J. Johnston, M. Hristopoulos, R. Clark, D. Ellerman, B. E. Wang, Y. Li, M. Mathieu, G. Li, J. Young, E. Luis, P. G. Lewis, E. Stefanich, C. Spiess, A. Polson, B. Irving, J. M. Scheer, M. R. Junttila, M. S. Dennis, R. Kelley, K. Totpal, A. Ebens, Cancer Res. 2014, 74, 5561-5571.
- (2014) Cancer Res. , vol.74 , pp. 5561-5571
- Junttila, T.T.¹ Li, J.² Johnston, J.³ Hristopoulos, M.⁴ Clark, R.⁵ Ellerman, D.⁶ Wang, B.E.⁷ Li, Y.⁸ Mathieu, M.⁹ Li, G.¹⁰ Young, J.¹¹ Luis, E.¹² Lewis, P.G.¹³ Stefanich, E.¹⁴ Spiess, C.¹⁵ Polson, A.¹⁶ Irving, B.¹⁷ Scheer, J.M.¹⁸ Junttila, M.R.¹⁹ Dennis, M.S.²⁰ more..

10
- 77955433583
- R. Lutterbuese, T. Raum, R. Kischel, P. Hoffmann, S. Mangold, B. Rattel, M. Friedrich, O. Thomas, G. Lorenczewski, D. Rau, E. Schaller, I. Herrmann, A. Wolf, T. Urbig, P. A. Baeuerle, P. Kufer, Proc. Natl. Acad. Sci. USA 2010, 107, 12605-12610.
- (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 12605-12610
- Lutterbuese, R.¹ Raum, T.² Kischel, R.³ Hoffmann, P.⁴ Mangold, S.⁵ Rattel, B.⁶ Friedrich, M.⁷ Thomas, O.⁸ Lorenczewski, G.⁹ Rau, D.¹⁰ Schaller, E.¹¹ Herrmann, I.¹² Wolf, A.¹³ Urbig, T.¹⁴ Baeuerle, P.A.¹⁵ Kufer, P.¹⁶

11
- 84856007019
- M. Cioffi, J. Dorado, P. A. Baeuerle, C. Heeschen, Clin. Cancer Res. 2012, 18, 465-474.
- (2012) Clin. Cancer Res. , vol.18 , pp. 465-474
- Cioffi, M.¹ Dorado, J.² Baeuerle, P.A.³ Heeschen, C.⁴

12
- 1542713413
- Y. Gao, D. Xiong, M. Yang, H. Liu, H. Peng, X. Shao, Y. Xu, C. Xu, D. Fan, L. Qin, C. Yang, Z. Zhu, Leukemia 2004, 18, 513-520.
- (2004) Leukemia , vol.18 , pp. 513-520
- Gao, Y.¹ Xiong, D.² Yang, M.³ Liu, H.⁴ Peng, H.⁵ Shao, X.⁶ Xu, Y.⁷ Xu, C.⁸ Fan, D.⁹ Qin, L.¹⁰ Yang, C.¹¹ Zhu, Z.¹²

13
- 84897568616
- S. L. Maude, D. Barrett, D. T. Teachey, S. A. Grupp, Cancer J. 2014, 20, 119-122.
- (2014) Cancer J. , vol.20 , pp. 119-122
- Maude, S.L.¹ Barrett, D.² Teachey, D.T.³ Grupp, S.A.⁴

14
- 84873353521
- P. Fournier, V. Schirrmacher, BioDrugs 2013, 27, 35-53.
- (2013) BioDrugs , vol.27 , pp. 35-53
- Fournier, P.¹ Schirrmacher, V.²

15
- 77951523463
- P. Chames, D. Baty, MAbs 2009, 1, 539-547.
- (2009) MAbs , vol.1 , pp. 539-547
- Chames, P.¹ Baty, D.²

16
- 84862538751
- C. H. Kim, J. Y. Axup, A. Dubrovska, S. A. Kazane, B. A. Hutchins, E. D. Wold, V. V. Smider, P. G. Schultz, J. Am. Chem. Soc. 2012, 134, 9918-9921.
- (2012) J. Am. Chem. Soc. , vol.134 , pp. 9918-9921
- Kim, C.H.¹ Axup, J.Y.² Dubrovska, A.³ Kazane, S.A.⁴ Hutchins, B.A.⁵ Wold, E.D.⁶ Smider, V.V.⁷ Schultz, P.G.⁸

17
- 33847648384
- W. Liu, A. Brock, S. Chen, S. Chen, P. G. Schultz, Nat. Methods 2007, 4, 239-244.
- (2007) Nat. Methods , vol.4 , pp. 239-244
- Liu, W.¹ Brock, A.² Chen, S.³ Chen, S.⁴ Schultz, P.G.⁵

18
- 0035917812
- L. Wang, A. Brock, B. Herberich, P. G. Schultz, Science 2001, 292, 498-500.
- (2001) Science , vol.292 , pp. 498-500
- Wang, L.¹ Brock, A.² Herberich, B.³ Schultz, P.G.⁴

19
- 79951678678
- B. M. Hutchins, S. A. Kazane, K. Staflin, J. S. Forsyth, B. Felding-Habermann, P. G. Schultz, V. V. Smider, J. Mol. Biol. 2011, 406, 595-603.
- (2011) J. Mol. Biol. , vol.406 , pp. 595-603
- Hutchins, B.M.¹ Kazane, S.A.² Staflin, K.³ Forsyth, J.S.⁴ Felding-Habermann, B.⁵ Schultz, P.G.⁶ Smider, V.V.⁷

20
- 84867040452
- J. Y. Axup, K. M. Bajjuri, M. Ritland, B. M. Hutchins, C. H. Kim, S. A. Kazane, R. Halder, J. S. Forsyth, A. F. Santidrian, K. Stafin, Y. Lu, H. Tran, A. J. Seller, S. L. Biroc, A. Szydlik, J. K. Pinkstaff, F. Tian, S. C. Sinha, B. Felding-Habermann, V. V. Smider, P. G. Schultz, Proc. Natl. Acad. Sci. USA 2012, 109, 16101-16106.
- (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 16101-16106
- Axup, J.Y.¹ Bajjuri, K.M.² Ritland, M.³ Hutchins, B.M.⁴ Kim, C.H.⁵ Kazane, S.A.⁶ Halder, R.⁷ Forsyth, J.S.⁸ Santidrian, A.F.⁹ Stafin, K.¹⁰ Lu, Y.¹¹ Tran, H.¹² Seller, A.J.¹³ Biroc, S.L.¹⁴ Szydlik, A.¹⁵ Pinkstaff, J.K.¹⁶ Tian, F.¹⁷ Sinha, S.C.¹⁸ Felding-Habermann, B.¹⁹ Smider, V.V.²⁰ Schultz, P.G.²¹ more..

21
- 78650102483
- J. Dommerholt, S. Schmidt, R. Temming, L. J. Hendriks, F. P. Rutjes, J. C. van Hest, D. J. Lefeber, P. Friedl, F. L. van Delft, Angew. Chem. Int. Ed. 2010, 49, 9422-9425
- (2010) Angew. Chem. Int. Ed. , vol.49 , pp. 9422-9425
- Dommerholt, J.¹ Schmidt, S.² Temming, R.³ Hendriks, L.J.⁴ Rutjes, F.P.⁵ Van Hest, J.C.⁶ Lefeber, D.J.⁷ Friedl, P.⁸ Van Delft, F.L.⁹

22
- 79954572120
- Angew. Chem. 2010, 122, 9612-9615.
- (2010) Angew. Chem. , vol.122 , pp. 9612-9615

23
- 84859992212
- J. E. Hudak, R. M. Barfield, G. W. de Hart, P. Grob, E. Nogales, C. R. Bertozzi, D. Rabuka, Angew. Chem. Int. Ed. 2012, 51, 4161-4165
- (2012) Angew. Chem. Int. Ed. , vol.51 , pp. 4161-4165
- Hudak, J.E.¹ Barfield, R.M.² De Hart, G.W.³ Grob, P.⁴ Nogales, E.⁵ Bertozzi, C.R.⁶ Rabuka, D.⁷

24
- 84871936058
- Angew. Chem. 2012, 124, 4237-4241.
- (2012) Angew. Chem. , vol.124 , pp. 4237-4241

25
- 84864310710
- D. M. Collins, N. O'Donovan, P. M. McGowan, F. O'Sullivan, M. J. Duffy, J. Crown, Ann. Oncol. 2012, 23, 1788-1795.
- (2012) Ann. Oncol. , vol.23 , pp. 1788-1795
- Collins, D.M.¹ O'Donovan, N.² McGowan, P.M.³ O'Sullivan, F.⁴ Duffy, M.J.⁵ Crown, J.⁶

26
- 57249094344
- K. McLarty, B. Cornelissen, D. A. Scollard, S. J. Done, K. Chun, R. M. Reilly, Eur. J. Nucl. Med. Mol. Imaging 2009, 36, 81-93.
- (2009) Eur. J. Nucl. Med. Mol. Imaging , vol.36 , pp. 81-93
- McLarty, K.¹ Cornelissen, B.² Scollard, D.A.³ Done, S.J.⁴ Chun, K.⁵ Reilly, R.M.⁶

27
- 0036554863
- J. W. Park, K. Hong, D. B. Kirpotin, G. Colbern, R. Shalaby, J. Baselga, Y. Shao, U. B. Nielsen, J. D. Marks, D. Moore, D. Papahadjopoulos, C. C. Benz, Clin. Cancer Res. 2002, 8, 1172-1181.
- (2002) Clin. Cancer Res. , vol.8 , pp. 1172-1181
- Park, J.W.¹ Hong, K.² Kirpotin, D.B.³ Colbern, G.⁴ Shalaby, R.⁵ Baselga, J.⁶ Shao, Y.⁷ Nielsen, U.B.⁸ Marks, J.D.⁹ Moore, D.¹⁰ Papahadjopoulos, D.¹¹ Benz, C.C.¹²

28
- 79955088678
- L. DeFazio-Eli, K. Strommen, T. Dao-Pick, G. Parry, L. Goodman, J. Winslow, Breast Cancer Res. 2011, 13, R 44.
- (2011) Breast Cancer Res. , vol.13 , pp. R44
- DeFazio-Eli, L.¹ Strommen, K.² Dao-Pick, T.³ Parry, G.⁴ Goodman, L.⁵ Winslow, J.⁶

29
- 82255167636
- J. L. Nordstrom, S. Gorlatov, W. Zhang, Y. Yang, L. Huang, S. Burke, H. Li, V. Ciccarone, T. Zhang, J. Stavenhagen, S. Koenig, S. J. Stewart, P. A. Moore, S. Johnson, E. Bonvini, Breast Cancer Res. 2011, 13, R 123.
- (2011) Breast Cancer Res. , vol.13 , pp. R123
- Nordstrom, J.L.¹ Gorlatov, S.² Zhang, W.³ Yang, Y.⁴ Huang, L.⁵ Burke, S.⁶ Li, H.⁷ Ciccarone, V.⁸ Zhang, T.⁹ Stavenhagen, J.¹⁰ Koenig, S.¹¹ Stewart, S.J.¹² Moore, P.A.¹³ Johnson, S.¹⁴ Bonvini, E.¹⁵

30
- 79954614868
- L. D. Tan, Y. Y. Xu, Y. Yu, X. Q. Li, Y. Chen, Y. M. Feng, PLoS One 2011, 6, e 18764.
- (2011) PLoS One , vol.6
- Tan, L.D.¹ Xu, Y.Y.² Yu, Y.³ Li, X.Q.⁴ Chen, Y.⁵ Feng, Y.M.⁶

31
- 1542511907
- I. O. Ellis, J. Bartlett, M. Dowsett, S. Humphreys, B. Jasani, K. Miller, S. E. Pinder, A. Rhodes, R. Walker, J. Clin. Pathol. 2004, 57, 233-237.
- (2004) J. Clin. Pathol. , vol.57 , pp. 233-237
- Ellis, I.O.¹ Bartlett, J.² Dowsett, M.³ Humphreys, S.⁴ Jasani, B.⁵ Miller, K.⁶ Pinder, S.E.⁷ Rhodes, A.⁸ Walker, R.⁹

32
- 0034864020
- J. Baselga, Ann. Oncol. 2001, 12 Suppl 1, S 49 -S 55.
- (2001) Ann. Oncol. , vol.12 , pp. S49-S55
- Baselga, J.¹

33
- 0000351142
- D. A. Cantrell, A. A. Davies, M. J. Crumpton, Proc. Natl. Acad. Sci. USA 1985, 82, 8158-8162.
- (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8158-8162
- Cantrell, D.A.¹ Davies, A.A.² Crumpton, M.J.³

34
- 77954472387
- D. A. Schmid, M. B. Irving, V. Posevitz, M. Hebeisen, A. Posevitz-Fejfar, J. C. Sarria, R. Gomez-Eerland, M. Thome, T. N. Schumacher, P. Romero, D. E. Speiser, V. Zoete, O. Michielin, N. Rufer, J. Immunol. 2010, 184, 4936-4946.
- (2010) J. Immunol. , vol.184 , pp. 4936-4946
- Schmid, D.A.¹ Irving, M.B.² Posevitz, V.³ Hebeisen, M.⁴ Posevitz-Fejfar, A.⁵ Sarria, J.C.⁶ Gomez-Eerland, R.⁷ Thome, M.⁸ Schumacher, T.N.⁹ Romero, P.¹⁰ Speiser, D.E.¹¹ Zoete, V.¹² Michielin, O.¹³ Rufer, N.¹⁴

35
- 20044375937
- K. C. Herold, S. E. Gitelman, U. Masharani, W. Hagopian, B. Bisikirska, D. Donaldson, K. Rother, B. Diamond, D. M. Harlan, J. A. Bluestone, Diabetes 2005, 54, 1763-1769.
- (2005) Diabetes , vol.54 , pp. 1763-1769
- Herold, K.C.¹ Gitelman, S.E.² Masharani, U.³ Hagopian, W.⁴ Bisikirska, B.⁵ Donaldson, D.⁶ Rother, K.⁷ Diamond, B.⁸ Harlan, D.M.⁹ Bluestone, J.A.¹⁰

36
- 0031806536
- B. K. Link, S. A. Kostelny, M. S. Cole, W. P. Fusselman, J. Y. Tso, G. J. Weiner, Int. J. Cancer 1998, 77, 251-256.
- (1998) Int. J. Cancer , vol.77 , pp. 251-256
- Link, B.K.¹ Kostelny, S.A.² Cole, M.S.³ Fusselman, W.P.⁴ Tso, J.Y.⁵ Weiner, G.J.⁶

37
- 0028883642
- R. Belani, G. J. Weiner, J. Hematother. 1995, 4, 395-402.
- (1995) J. Hematother. , vol.4 , pp. 395-402
- Belani, R.¹ Weiner, G.J.²

38
- 33744803712
- P. Kiewe, S. Hasmuller, S. Kahlert, M. Heinrigs, B. Rack, A. Marme, A. Korfel, M. Jager, H. Lindhofer, H. Sommer, E. Thiel, M. Untch, Clin. Cancer Res. 2006, 12, 3085-3091.
- (2006) Clin. Cancer Res. , vol.12 , pp. 3085-3091
- Kiewe, P.¹ Hasmuller, S.² Kahlert, S.³ Heinrigs, M.⁴ Rack, B.⁵ Marme, A.⁶ Korfel, A.⁷ Jager, M.⁸ Lindhofer, H.⁹ Sommer, H.¹⁰ Thiel, E.¹¹ Untch, M.¹²

39
- 84893452692
- F. Tian, Y. Lu, A. Manibusan, A. Sellers, H. Tran, Y. Sun, T. Phuong, R. Barnett, B. Hehli, F. Song, M. J. DeGuzman, S. Ensari, J. K. Pinkstaff, L. M. Sullivan, S. L. Biroc, H. Cho, P. G. Schultz, J. DiJoseph, M. Dougher, D. Ma, R. Dushin, M. Leal, L. Tchistiakova, E. Feyfant, H. P. Gerber, P. Sapra, Proc. Natl. Acad. Sci. USA 2014, 111, 1766-1771.
- (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 1766-1771
- Tian, F.¹ Lu, Y.² Manibusan, A.³ Sellers, A.⁴ Tran, H.⁵ Sun, Y.⁶ Phuong, T.⁷ Barnett, R.⁸ Hehli, B.⁹ Song, F.¹⁰ Deguzman, M.J.¹¹ Ensari, S.¹² Pinkstaff, J.K.¹³ Sullivan, L.M.¹⁴ Biroc, S.L.¹⁵ Cho, H.¹⁶ Schultz, P.G.¹⁷ Dijoseph, J.¹⁸ Dougher, M.¹⁹ Ma, D.²⁰ more..

40
- 84898005371
- D. Jackson, J. Atkinson, C. I. Guevara, C. Zhang, V. Kery, S. J. Moon, C. Virata, P. Yang, C. Lowe, J. Pinkstaff, H. Cho, N. Knudsen, A. Manibusan, F. Tian, Y. Sun, Y. Lu, A. Sellers, X. C. Jia, I. Joseph, B. Anand, K. Morrison, D. S. Pereira, D. Stover, PLoS One 2014, 9, e83865.
- (2014) PLoS One , vol.9
- Jackson, D.¹ Atkinson, J.² Guevara, C.I.³ Zhang, C.⁴ Kery, V.⁵ Moon, S.J.⁶ Virata, C.⁷ Yang, P.⁸ Lowe, C.⁹ Pinkstaff, J.¹⁰ Cho, H.¹¹ Knudsen, N.¹² Manibusan, A.¹³ Tian, F.¹⁴ Sun, Y.¹⁵ Lu, Y.¹⁶ Sellers, A.¹⁷ Jia, X.C.¹⁸ Joseph, I.¹⁹ Anand, B.²⁰ more..

41
- 84897018652
- Y. Cao, J. W. Marks, Z. Liu, L. H. Cheung, W. N. Hittelman, M. G. Rosenblum, Oncogene 2014, 33, 429-439.
- (2014) Oncogene , vol.33 , pp. 429-439
- Cao, Y.¹ Marks, J.W.² Liu, Z.³ Cheung, L.H.⁴ Hittelman, W.N.⁵ Rosenblum, M.G.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.