Generation of mutant uukuniemi viruses lacking the nonstructural protein nss by reverse genetics indicates that NSs is a weak interferon antagonist

Journal of Virology

Volumn 89, Issue 9, 2015, Pages 4849-4856

  Rezelj, Veronica V ^a   överby, Anna K ^b   Elliott, Richard M ^a  

^a MRC UNIVERSITY OF GLASGOW CENTRE FOR VIRUS RESEARCH   (United Kingdom)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERFERON; NONSTRUCTURAL PROTEIN NS; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA; COMPLEMENTARY DNA; VIRUS DNA;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; GENE DELETION; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; NS GENE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; REVERSE GENETICS; UUKUNIEMI VIRUS; VIROGENESIS; VIRUS ATTENUATION; VIRUS GENE; VIRUS GENOME; VIRUS INFECTION; VIRUS MORPHOLOGY; VIRUS MUTANT; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE; WILD TYPE; ANTAGONISTS AND INHIBITORS; CELL LINE; GENETIC RECOMBINATION; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

BUNYAVIRIDAE; IXODIDA; ORTHOBUNYAVIRUS; PHLEBOVIRUS; UUKUNIEMI VIRUS;

CELL LINE; DNA, COMPLEMENTARY; DNA, VIRAL; GENE DELETION; HUMANS; INTERFERONS; RECOMBINATION, GENETIC; REVERSE GENETICS; UUKUNIEMI VIRUS; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84928543269     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03511-14     Document Type: Article

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