The JAK-STAT signaling pathway is differentially activated in CALR-positive compared with JAK2V617F-positive ET patients

Blood

Volumn 125, Issue 10, 2015, Pages 1679-1681

  Lau, Winnie W Y ^a   Hannah, Rebecca ^a   Green, Anthony R ^a,b   Göttgens, Bertie ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALR PROTEIN; JANUS KINASE 2; PROTEIN; SHORT HAIRPIN RNA; STAT1 PROTEIN; STAT3 PROTEIN; STAT5A PROTEIN; THROMBOPOIETIN; UNCLASSIFIED DRUG; CALRETICULIN; CALRETICULIN, HUMAN; JAK2 PROTEIN, HUMAN; MUTANT PROTEIN; STAT PROTEIN;

CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; EMBRYONIC STEM CELL; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE ONTOLOGY; GRANULOCYTE; HUMAN; LETTER; MEGAKARYOCYTE; MICROARRAY ANALYSIS; MYELOPROLIFERATIVE NEOPLASM; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WILD TYPE; AMINO ACID SUBSTITUTION; GENETICS; METABOLISM; MUTATION; THROMBOCYTHEMIA;

AMINO ACID SUBSTITUTION; CALRETICULIN; GENE ONTOLOGY; HUMANS; JANUS KINASE 2; MEGAKARYOCYTES; MUTANT PROTEINS; MUTATION; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; THROMBOCYTHEMIA, ESSENTIAL;

EID: 84928430930     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-12-618074     Document Type: Letter

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