Deletion of the major bullous pemphigoid epitope region of collagen XVII induces blistering, autoimmunization, and itching in mice

Journal of Investigative Dermatology

Volumn 135, Issue 5, 2015, Pages 1303-1310

  Hurskainen, Tiina ^a,b   Kokkonen, Nina ^a,b   Sormunen, Raija ^a   Jackow, Joanna ^c   Löffek, Stefanie ^d   Soininen, Raija ^a   Franzke, Claus Werner ^d   Bruckner Tuderman, Leena ^d   Tasanen, Kaisa ^a,b  

^a UNIVERSITY OF OULU   (Finland)

^b OULU UNIVERSITY HOSPITAL   (Finland)

^c IMAGINE INSTITUTE   (France)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; COLLAGEN TYPE 17; COLLAGENASE; EPITOPE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G ANTIBODY; NONCOLLAGENOUS 16A; PROTEIN; UNCLASSIFIED DRUG; AUTOANTIGEN; NONFIBRILLAR COLLAGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; BASEMENT MEMBRANE; BULLOUS PEMPHIGOID; CELL INFILTRATION; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; EOSINOPHILIA; FEMALE; GENE DELETION; GENETICALLY ENGINEERED MOUSE STRAIN; HEMIDESMOSOME; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOLOGICAL TOLERANCE; MALE; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PRURITUS; ANIMAL; BLISTER; BLOOD; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; GENETICS; KERATINOCYTE; KNOCKOUT MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNITY; BLISTER; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPITOPES; GENE DELETION; KERATINOCYTES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NON-FIBRILLAR COLLAGENS; PEMPHIGOID, BULLOUS; PHENOTYPE; PRURITUS; SKIN;

EID: 84928407752     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.443     Document Type: Article

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