Evaluation of Hypoglycemic Efficacy of Tangningtongluo Formula, a Traditional Chinese Miao Medicine, in Two Rodent Animal Models

Journal of Diabetes Research

Volumn 2014, Issue , 2014, Pages

  Cheng, Long ^a   Meng, Xiang Bao ^a   Lu, Shan ^b   Wang, Ting Ting ^c   Liu, Yue ^d   Sun, Gui Bo ^a   Sun, Xiao Bo ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^c HARBIN UNIVERSITY OF COMMERCE   (China)

^d XIYUAN HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; C PEPTIDE; CHINESE DRUG; CHOLESTEROL; CREATININE; GLICLAZIDE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; METFORMIN; PLANT EXTRACT; TANGNINGTONGLUO; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; HERBACEOUS AGENT; STREPTOZOCIN;

AGRIMONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; APOPTOSIS; ARTICLE; CHINESE MEDICINE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; DIET RESTRICTION; DISEASE SEVERITY; DRUG EFFICACY; DRUG FORMULATION; FLUORESCENCE ANGIOGRAPHY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HISTOPATHOLOGY; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; KIDNEY FUNCTION; LIPID DIET; LIVER CELL DAMAGE; LIVER FUNCTION; LONICERA; MALE; MOUSE; MOUSE MODEL; NONHUMAN; OPTIC NERVE FIBER; OPTICAL COHERENCE TOMOGRAPHY; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL HYPERPLASIA; PANCREAS NECROSIS; PLANTAGINACEAE; PRIORITY JOURNAL; RAT; RAT MODEL; RETINA NEOVASCULARIZATION; RETINAL NERVE FIBER LAYER THICKNESS; RISK REDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL; ANIMAL; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DRUG EFFECTS; METABOLISM; NECROSIS; PATHOLOGY; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; BIOMARKERS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DIABETIC RETINOPATHY; DIET, HIGH-FAT; DRUGS, CHINESE HERBAL; HEMOGLOBIN A, GLYCOSYLATED; HYPOGLYCEMIC AGENTS; ISLETS OF LANGERHANS; MALE; METFORMIN; MICE, INBRED C57BL; NECROSIS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; TIME FACTORS;

EID: 84928401233     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2014/745419     Document Type: Article

References (28)

1. World Health Organization, http://www.who.int/diabetes/action online/basics/zh/index3.html.
2. M. Marcovecchio, A. Mohn, and F. Chiarelli, "Type 2 diabetes mellitus in children and adolescents, " Journal of Endocrinological Investigation, vol. 28, no. 9, pp. 853-863, 2005.
3. J. C. N. Chan, V. Malik, W. Jia et al., "Diabetes in Asia: epidemiology, risk factors, and pathophysiology, " Journal of the American Medical Association, vol. 301, no. 20, pp. 2129-2140, 2009.
4. A. R. Saltiel and C. R. Kahn, "Insulin signalling and the regulation of glucose and lipid metabolism, " Nature, vol. 414, no. 6865, pp. 799-806, 2001.
5. S. Wild, G. Roglic, A. Green, R. Sicree, and H. King, "Global prevalence of diabetes: estimates for the year 2000 and projections for 2030, " Diabetes Care, vol. 27, no. 5, pp. 1047-1053, 2004.
6. W. Xie, Y. Zhao, and Y. Zhang, "Traditional Chinese medicines in treatment of patients with type 2 diabetes mellitus, " Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 726723, 13 pages, 2011.
7. D. R.Whiting, L.Guariguata, C.Weil, andJ.Shaw, "IDFdiabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030, " Diabetes Research and Clinical Practice, vol. 94, no. 3, pp. 311-321, 2011.
8. International Diabetes Federation, http://www.idf.org/worlddiabetesday/toolkit/gp/facts-figures.
9. American Diabetes Association, "Economic costs of diabetes in the U.S. in 2007, " Diabetes Care, vol. 31, no. 3, pp. 3596-3615, 2008.
10. American Diabetes Association, "Standards of medical care in diabetes - 2012, " Diabetes Care, vol. 35, supplement 1, pp. S11-S63, 2012.
11. Z. Wang, J. Wang, and P. Chan, "Treating type 2 diabetes mellitus with traditional Chinese and indian medicinal herbs, " Evidence-based Complementary and Alternative Medicine, vol. 2013, Article ID 343594, 17 pages, 2013.
12. B. Maggie, "Traditional Chinese medicine in the treatment of diabetes, " Diabetes Spectrum, vol. 14, no. 3, pp. 154-159, 2001.
13. L. Cheng, G.-F. Pan, X.-B. Sun, Y.-X. Huang, Y.-S. Peng, and L.-Y. Zhou, "Evaluation of anxiolytic-like effect of aqueous extract of asparagus stemin mice, " Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 587260, 10 pages, 2013.
14. V. E. Tyler, "Herbalmedicine: fromthe past to the future, " Public Health Nutrition, vol. 3, no. 4, pp. 447-452, 2000.
15. M. J. Reed, K. Meszaros, L. J. Entes et al., "A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat, " Metabolism: Clinical and Experimental, vol. 49, no. 11, pp. 1390-1394, 2000.
16. F. L. Zhang, C. Ye, G. Li et al., "The rat model of type 2 diabetic mellitus and its glycometabolism characters, " Experimental Animals, vol. 52, no. 5, pp. 401-407, 2003.
17. H. Chen, O. Charlat, L. A. Tartaglia et al., "Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice, " Cell, vol. 84, no. 3, pp. 491-495, 1996.
18. K. Kaku, M. Province, and M. A. Permutt, "Genetic analysis of obesity-induced diabetes associated with a limited capacity to synthesize insulin in C57BL/KS mice: evidence for polygenic control, " Diabetologia, vol. 32, no. 9, pp. 636-643, 1989.
19. H. Kodama, M. Fujita, and I. Yamaguchi, "Development of hyperglycaemia and insulin resistance in conscious genetically diabetic (C57BL/KsJ-db/db) mice, " Diabetologia, vol. 37, no. 8, pp. 739-744, 1994.
20. UNESCO, http://portal.unesco.org/en/ev.php-URL ID=28188 &URL DO=DO TOPIC&URL SECTION=201.html.
21. P. S. Sona, "Nanoparticulate drug delivery systems for the treatment of diabetes, " Digest Journal of Nanomaterials and Biostructures, vol. 5, no. 2, pp. 411-418, 2010.
22. A.-G.Meng and L.-L. Jiang, "Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway, " Acta Pharmacologica Sinica, vol. 30, no. 4, pp. 442-450, 2009.
23. WHO, WHO Monographs on Selected Medicinal Plants, vol. 1, WHO, Geneva, Switzerland, 1999.
24. W.-Y. Jiang, "Therapeutic wisdom in traditional Chinese medicine: a perspective from modern science, " Trends in Pharmacological Sciences, vol. 26, no. 11, pp. 558-563, 2005.
25. R. Yuan and Y. Lin, "Traditional Chinese medicinean approach to scientific proof and clinical validation, " Pharmacology and Therapeutics, vol. 86, no. 2, pp. 191-198, 2000.
26. National Center for Complementary and AlternativeMedicine, http://nccam.nih.gov/health/whatiscam/chinesemed.htm.
27. WHO, "Definition and diagnosis of diabetes mellitus and intermediate hyperglycaemia, " (Report of a WHO/IDF Consultation), http://whqlibdoc.who.int/publications/2006/9241594934 eng.pdf.
28. M. Motshakeri, M. Ebrahimi, Y. M. Goh, H. H. Othman, M. Hair-Bejo, and S. Mohamed, "Effects of brown seaweed (Sargassum polycystum) extracts on kidney, liver, and pancreas of type 2 diabetic rat model, " Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 379407, 11 pages, 2014.